Reduced numbers of Sertoli, germ, and spermatogonial stem cells in impaired spermatogenesis

scientific article published on 17 June 2011

Reduced numbers of Sertoli, germ, and spermatogonial stem cells in impaired spermatogenesis is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1004991689
P356DOI10.1038/MODPATHOL.2011.97
P698PubMed publication ID21685910

P2093author name stringSabine Kliesch
Martin Bergmann
Lutz Konrad
Georg H Lüers
Martin Wolter
Anna Hentrich
Carolin Szardening-Kirchner
P2860cites workQuantitative analysis of testicle biopsy: determination of partial obstruction and prediction of sperm count after surgery for obstructionQ70941351
Germinal cell loss during human spermatogenesisQ71776073
Quantitation of the cells of the seminiferous epithelium of the human testis employing the sertoli cell as a constantQ71785644
Meiotic events at the centromeric heterochromatin: histone H3 phosphorylation, topoisomerase II alpha localization and chromosome condensationQ73399875
Maturation phenotype of Sertoli cells in testicular biopsies of azoospermic menQ73942947
Testicular cAMP responsive element modulator (CREM) protein is expressed in round spermatids but is absent or reduced in men with round spermatid maturation arrestQ74335953
Absence of cyclic adenosine 3':5' monophosphate responsive element modulator expression at the spermatocyte arrest stageQ74413795
Quantitative investigations on human testicular biopsies. II. Infertility and other conditionsQ74492498
Key role for cyclin-dependent kinases in the first and second meiotic divisions of rat spermatocytesQ75208794
Spermatogonial proliferation and apoptosis in hypospermatogenesis associated with nonobstructive azoospermiaQ77156777
Spermatogonial proliferation patterns in men with azoospermia of different etiologiesQ79273355
Detection of calretinin expression in abnormal immature Sertoli cells in non-obstructive azoospermiaQ81837897
Changes in the expression profile of the meiosis-involved mismatch repair genes in impaired human spermatogenesisQ82520555
Presumed pluripotency markers UTF-1 and REX-1 are expressed in human adult testes and germ cell neoplasmsQ24314617
UTF1, a novel transcriptional coactivator expressed in pluripotent embryonic stem cells and extra-embryonic cellsQ24533198
Alteration of transforming growth factor-beta signaling system expression in adult rat germ cells with a chronic apoptotic cell death process after fetal androgen disruptionQ28569512
Reversion of the differentiated phenotype and maturation block in Sertoli cells in pathological human testis.Q30321201
The proliferation of spermatogonia in normal and pathological human seminiferous epithelium: an immunohistochemical study using monoclonal antibodies against Ki-67 protein and proliferating cell nuclear antigen.Q30321281
Alternative splicing of TGF-betas and their high-affinity receptors T beta RI, T beta RII and T beta RIII (betaglycan) reveal new variants in human prostatic cellsQ33298457
Androgens and spermatogenesis: lessons from transgenic mouse models.Q33856942
Proliferation and functional maturation of Sertoli cells, and their relevance to disorders of testis function in adulthoodQ34200910
Testicular expression of synaptonemal complex protein 3 (SYCP3) messenger ribonucleic acid in 110 patients with nonobstructive azoospermiaQ34545268
Phosphorylation of serine 10 in histone H3, what for?Q35199083
Testis-specific transcription mechanisms promoting male germ-cell differentiationQ35825421
Meiotic abnormalities in infertile males.Q36271592
Histological evaluation of the human testis--approaches to optimizing the clinical value of the assessment: mini reviewQ36556325
A tale of two proteins: differential roles and regulation of Smad2 and Smad3 in TGF-beta signalingQ36752829
Role of Sertoli cell number and function on regulation of spermatogenesisQ37074841
Surfing the wave, cycle, life history, and genes/proteins expressed by testicular germ cells. Part 5: intercellular junctions and contacts between germs cells and Sertoli cells and their regulatory interactions, testicular cholesterol, and genes/proQ37639265
Expression of the pluripotency marker UTF1 is restricted to a subpopulation of early A spermatogonia in rat testis.Q38292040
Isolation, characterization, and culture of human spermatogoniaQ42117420
Developmental and stage-specific expression of Smad2 and Smad3 in rat testisQ44360250
Normal expression of isoforms activating cyclic adenosine monophosphate responsive element modulator in patients with spermatid maturation arrestQ45098046
Germ cell-specific cyclic adenosine 3',5'-monophosphate response element modulator expression in rodent and primate testis is maintained despite gonadotropin deficiencyQ46559756
Stereological analysis of the human testis after vasectomy indicates impairment of spermatogenic efficiency with increasing obstructive intervalQ47355734
Age-related variation in seminiferous tubules in men. A stereologic evaluation.Q50907743
Abnormal meiotic recombination in infertile men and its association with sperm aneuploidy.Q53531556
Abnormal progression through meiosis in men with nonobstructive azoospermia.Q53585199
Screening for biomarkers of spermatogonia within the human testis: a whole genome approach.Q54438354
Quantitative pathologic changes in the human testis after vasectomy. A controlled study.Q54683990
Cytogenetic and Molecular Genetic InvestigationsQ62128410
Endocrine Laboratory DiagnosisQ62128413
Meiotic studies in a series of 1100 infertile and sterile malesQ63279602
Quantitative analysis of the seminiferous epithelium in human testicular biopsies, and the relation of spermatogenesis to sperm densityQ67403782
Quantification of human seminiferous epithelium. I. Histological studies in twenty-one fertile men with normal chromosome complementsQ69492533
Quantification of human seminiferous epithelium. II. Histological studies in eight 47,XYY menQ69492537
Quantitative analysis of testicular histology in patients with vas deferens obstruction caused by childhood inguinal herniorrhaphy: comparison to vasectomized menQ70892517
P433issue10
P304page(s)1380-1389
P577publication date2011-06-17
P1433published inModern PathologyQ15724578
P1476titleReduced numbers of Sertoli, germ, and spermatogonial stem cells in impaired spermatogenesis
P478volume24

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cites work (P2860)
Q38876440Causes and Clinical Features of Infertile Men With Nonobstructive Azoospermia and Histopathologic Diagnosis of Hypospermatogenesis
Q92483354Downregulation of Sostdc1 in Testicular Sertoli Cells is Prerequisite for Onset of Robust Spermatogenesis at Puberty
Q36093773Highly Conserved Testicular Localization of Claudin-11 in Normal and Impaired Spermatogenesis
Q41942551Pathological changes of testicular tissue in normal adult mice: A retrospective analysis
Q100425535Personalized Medicine for the Infertile Male
Q41415082RIPK1-RIPK3-MLKL-dependent necrosis promotes the aging of mouse male reproductive system.
Q92603190Retinoid-related orphan nuclear receptor alpha (RORα)-deficient mice display morphological testicular defects
Q36359253Sertoli-cell-specific knockout of connexin 43 leads to multiple alterations in testicular gene expression in prepubertal mice
Q26744780Spermatogonial stem cell autotransplantation and germline genomic editing: a future cure for spermatogenic failure and prevention of transmission of genomic diseases
Q34424014Testicular cell indices and peripheral blood testosterone concentrations in relation to age and semen quality in crossbred (holstein friesian×tharparkar) bulls.
Q90739537miRNA-31-5p Mediates the Proliferation and Apoptosis of Human Spermatogonial Stem Cells via Targeting JAZF1 and Cyclin A2

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