Downregulation of Sostdc1 in Testicular Sertoli Cells is Prerequisite for Onset of Robust Spermatogenesis at Puberty

scientific article published on 07 August 2019

Downregulation of Sostdc1 in Testicular Sertoli Cells is Prerequisite for Onset of Robust Spermatogenesis at Puberty is …
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scholarly articleQ13442814

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P356DOI10.1038/S41598-019-47930-X
P932PMC publication ID6686024
P698PubMed publication ID31391487

P50authorBhola Shankar PradhanQ61161619
P2093author name stringSubeer S Majumdar
Indrashis Bhattacharya
Rajesh Sarkar
P2860cites workBmp4 is required for the generation of primordial germ cells in the mouse embryoQ24608134
Distinct modes of inhibition by sclerostin on bone morphogenetic protein and Wnt signaling pathwaysQ24621990
Dickkopf homolog 3 (DKK3) plays a crucial role upstream of WNT/β-CATENIN signaling for Sertoli cell mediated regulation of spermatogenesisQ27320201
Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knotQ28185030
Wnt4 is required for proper male as well as female sexual developmentQ28513410
Wise regulates bone deposition through genetic interactions with Lrp5Q33553692
Id2 promotes apoptosis by a novel mechanism independent of dimerization to basic helix-loop-helix factorsQ33778826
The circadian clock protein BMAL1 is necessary for fertility and proper testosterone production in miceQ33821636
Neonatal gonadotropin therapy in male congenital hypogonadotropic hypogonadism.Q34225321
Consequences of knocking out BMP signaling in the mouseQ35025212
Regulation of spermatogenesis by paracrine/autocrine testicular factors.Q35845587
Sperm counts and fertility in men: a rocky road ahead. Science & Society Series on Sex and ScienceQ35931812
Inactivation of the dual Bmp/Wnt inhibitor Sostdc1 enhances pancreatic islet functionQ36309205
A human bone morphogenetic protein antagonist is down-regulated in renal cancerQ36438780
All in the family: TGF-beta family action in testis development.Q36555345
SOSTDC1 differentially modulates Smad and beta-catenin activation and is down-regulated in breast cancerQ36936190
The biology of infertility: research advances and clinical challengesQ37206451
Early versus late maturation arrest: reproductive outcomes of testicular failureQ37206479
An Efficient Method for Generation of Transgenic Rats Avoiding Embryo ManipulationQ37238776
Characterization of wise protein and its molecular mechanism to interact with both Wnt and BMP signalsQ37371753
A method for rapid generation of transgenic animals to evaluate testis genes during sexual maturationQ37625476
Loss of microRNA-7a2 induces hypogonadotropic hypogonadism and infertilityQ37672092
Genomic and post-genomic leads toward regulation of spermatogenesisQ38078643
The roles and regulation of Sertoli cells in fate determinations of spermatogonial stem cells and spermatogenesisQ38203438
Mechanical regulation of cancer cell apoptosis and autophagy: roles of bone morphogenetic protein receptor, Smad1/5, and p38 MAPK.Q39097851
A switch in Sertoli cell responsiveness to FSH may be responsible for robust onset of germ cell differentiation during prepubartal testicular maturation in rats.Q39304598
Role of TGF beta s and BMPs as signals controlling the position of the digits and the areas of interdigital cell death in the developing chick limb autopod.Q39427720
Wise retained in the endoplasmic reticulum inhibits Wnt signaling by reducing cell surface LRP6.Q40086323
BMP-7 opposes TGF-beta1-mediated collagen induction in mouse pulmonary myofibroblasts through Id2.Q40380725
Expression of the TGF-beta1 system in human testicular pathologiesQ41462009
Negative regulation of bone morphogenetic protein/Smad signaling by Cas-interacting zinc finger protein in osteoblastsQ42521645
Pem homeobox gene promoter sequences that direct transcription in a Sertoli cell-specific, stage-specific, and androgen-dependent manner in the testis in vivoQ44294694
The gene expression analysis of paracrine/autocrine factors in patients with spermatogenetic failure compared with normal spermatogenesis.Q44459374
The aryl hydrocarbon receptor is important for proper seminiferous tubule architecture and sperm development in miceQ45236147
Follicle-stimulating hormone-independent functions of primate Sertoli cells: potential implications in the diagnosis and management of male infertility.Q46861760
Testicular cells exhibit similar molecular responses to cigarette smoke condensate ex vivo and in vivoQ47787814
Hormone induced differential transcriptome analysis of Sertoli cells during postnatal maturation of rat testesQ48226555
Defective Wnt3 expression by testicular Sertoli cells compromise male fertilityQ48265176
Regulated Wnt/beta-catenin signaling sustains adult spermatogenesis in mice.Q50708161
Loss of Wnt5a disrupts primordial germ cell migration and male sexual development in mice.Q51854769
Inhibition of Wnt signaling by Wise (Sostdc1) and negative feedback from Shh controls tooth number and patterning.Q51901609
SMAD expression in the testis: an insight into BMP regulation of spermatogenesis.Q51970103
Role of BMP-2 and OP-1 (BMP-7) in programmed cell death and skeletogenesis during chick limb development.Q52195974
Low Sperm Counts May Be PreventableQ64447718
BMP-2/-4 mediate programmed cell death in chicken limb budsQ73023240
Epidemiology and aetiology of male infertilityQ74777194
The central role of Sertoli cells in spermatogenesisQ77545583
Short photoperiods evoke testicular apoptosis in white-footed mice (Peromyscus leucopus)Q77932827
Enhanced BMP signaling results in supernumerary tooth formation in USAG-1 deficient mouseQ80842466
Reduced numbers of Sertoli, germ, and spermatogonial stem cells in impaired spermatogenesisQ84391919
Advantages of pulsatile hormone treatment for assessing hormone-induced gene expression by cultured rat Sertoli cellsQ89356747
P433issue1
P304page(s)11458
P577publication date2019-08-07
P1433published inScientific ReportsQ2261792
P1476titleDownregulation of Sostdc1 in Testicular Sertoli Cells is Prerequisite for Onset of Robust Spermatogenesis at Puberty
P478volume9