Alternative splicing of TGF-betas and their high-affinity receptors T beta RI, T beta RII and T beta RIII (betaglycan) reveal new variants in human prostatic cells

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Alternative splicing of TGF-betas and their high-affinity receptors T beta RI, T beta RII and T beta RIII (betaglycan) reveal new variants in human prostatic cells is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1030715253
P356DOI10.1186/1471-2164-8-318
P932PMC publication ID2075524
P698PubMed publication ID17845732
P5875ResearchGate publication ID5994258

P2093author name stringHeidrun Brandt
Rainer Hofmann
Gerhard Aumüller
Lutz Konrad
Ansgar Schmidt
Elke Völck-Badouin
Jonas A Scheiber
Leslie Laible
Marcel M Keilani
P2860cites workHuman transforming growth factor type beta 2: production by a prostatic adenocarcinoma cell line, purification, and initial characterizationQ68766834
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Genetic change in transforming growth factor beta (TGF-beta) receptor type I gene correlates with insensitivity to TGF-beta 1 in human prostate cancer cellsQ70866425
A human transforming growth factor-beta type II receptor that contains an insertion in the extracellular domainQ71090132
Alternative splicing within the TGF-beta type I receptor gene (ALK-5) generates two major functional isoforms in vascular smooth muscle cellsQ73422801
Transforming growth factor-beta receptors in human cancer cell lines: analysis of transcript, protein and proliferationQ73496643
Preoperative plasma levels of transforming growth factor beta(1) (TGF-beta(1)) strongly predict progression in patients undergoing radical prostatectomyQ73959218
Analysis of the mRNA expression of the TGF-Beta family in testicular cells and localization of the splice variant TGF-beta2B in testisQ79991870
Diversity and modulation of plasminogen activator activity in human prostate carcinoma cell linesQ93863628
Cloning of a cDNA encoding the human transforming growth factor-beta type II receptor: heterogeneity of the mRNAQ28116060
Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory diseaseQ28202655
Abnormal lung development and cleft palate in mice lacking TGF-beta 3 indicates defects of epithelial-mesenchymal interactionQ28284617
Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient miceQ28361871
Heart and liver defects and reduced transforming growth factor beta2 sensitivity in transforming growth factor beta type III receptor-deficient embryosQ28508310
TGFβ2 knockout mice have multiple developmental defects that are non-overlapping with other TGFβ knockout phenotypesQ28592444
Defective haematopoiesis and vasculogenesis in transforming growth factor-β1 knock out miceQ28594495
TGF-beta signaling in tumor suppression and cancer progressionQ29615427
A genomic view of alternative splicingQ29615892
Predicting splice variant from DNA chip expression dataQ30655443
Truncation of the TGF-beta type II receptor gene results in insensitivity to TGF-beta in human gastric cancer cellsQ30699198
Inferring alternative splicing patterns in mouse from a full-length cDNA library and microarray dataQ30713065
High frequency of serum DNA alterations in renal cell carcinoma detected by fluorescent microsatellite analysisQ30831493
ASDB: database of alternatively spliced genesQ33610198
Alternative splicing and genome complexityQ33956410
Protein diversity from alternative splicing: a challenge for bioinformatics and post-genome biologyQ34084341
Latency, activation, and binding proteins of TGF-betaQ34136471
Structural and sequence analysis of TGF-beta 2 cDNA clones predicts two different precursor proteins produced by alternative mRNA splicingQ34556702
Alternative splicing: multiple control mechanisms and involvement in human diseaseQ34586931
Integration of the TGF-beta pathway into the cellular signalling networkQ34929949
ASAP: the Alternative Splicing Annotation ProjectQ35158228
Functions and regulation of transforming growth factor-beta (TGF-beta) in the prostateQ36088804
Cloning of an isoform of mouse TGF-beta type II receptor gene.Q36726542
Molecular cloning of a mouse counterpart for human TGF-beta type I receptorQ36743213
Transforming growth factor-beta 3 is required for secondary palate fusionQ37373842
Tissue expression of transforming growth factor-beta1 and its receptors: correlation with pathologic features and biochemical progression in patients undergoing radical prostatectomyQ38447431
EASED: Extended Alternatively Spliced EST DatabaseQ40403653
In the absence of type III receptor, the transforming growth factor (TGF)-beta type II-B receptor requires the type I receptor to bind TGF-beta2.Q40583089
The role of transforming growth factor-beta and its receptors in human prostate smooth muscle cell fibronectin productionQ40795836
Cell lineage characteristics of human prostatic stromal cells cultured in vitroQ40892591
Regulation of prostatic stromal cell growth and function by transforming growth factor beta (TGFbeta).Q40930461
Fibronectin in human prostatic cells in vivo and in vitro: expression, distribution, and pathological significanceQ40933445
Prostate specific membrane antigen (PSM) is expressed in various human tissues: implication for the use of PSM reverse transcription polymerase chain reaction to detect hematogenous prostate cancer spreadQ40965186
The conventional transforming growth factor-beta (TGF-beta) receptor type I is not required for TGF-beta 1 signaling in a human prostate cancer cell line, LNCaP.Q41032532
Comparative studies of the mitogenic effects of epidermal growth factor and transforming growth factor-alpha and the expression of various growth factors in neoplastic and non-neoplastic prostatic cell linesQ41123032
Differential gene expression of transforming growth factors alpha and beta, epidermal growth factor, keratinocyte growth factor, and their receptors in fetal and adult human prostatic tissues and cancer cell linesQ41147991
TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesisQ41159403
Expression of Recombinant TGF-β2(442) Precursor and Detection in BSC-40 CellsQ41699785
Alterations of expression and regulation of transforming growth factor beta in human cancer prostate cell linesQ42437180
Isolation and molecular characterization of the porcine transforming growth factor beta type I receptor (TGFBR1) geneQ42597291
Alternative splicing in the human, mouse and rat genomes is associated with an increased frequency of exon creation and/or lossQ46234594
The expression and structure of TGF-beta2 transcripts in rat musclesQ47844964
cDNA cloning of porcine transforming growth factor-beta 1 mRNAs. Evidence for alternate splicing and polyadenylation.Q48309411
Expression and function of TbetaRII-B, a variant of the type II TGF-beta receptor, in human chondrocytes.Q54566748
Type III TGF-beta receptor-independent signalling of TGF-beta2 via TbetaRII-B, an alternatively spliced TGF-beta type II receptorQ24290737
Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early deathQ24563654
Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primerQ27860572
P407language of work or nameEnglishQ1860
P921main subjectalternative mRNA splicing, via spliceosomeQ21114084
P304page(s)318
P577publication date2007-09-11
P1433published inBMC GenomicsQ15765854
P1476titleAlternative splicing of TGF-betas and their high-affinity receptors T beta RI, T beta RII and T beta RIII (betaglycan) reveal new variants in human prostatic cells
P478volume8

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cites work (P2860)
Q30495758Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant
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Q42474780Distribution of mRNAs encoding transforming growth factors-beta1, -2, and -3 in the intact rat brain and after experimentally induced focal ischemia
Q41668059Diverse effects of ANXA7 and p53 on LNCaP prostate cancer cells are associated with regulation of SGK1 transcription and phosphorylation of the SGK1 target FOXO3A
Q38171229Hallmarks of alternative splicing in cancer
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Q35788686Transcriptome Bioinformatical Analysis of Vertebrate Stages of Schistosoma japonicum Reveals Alternative Splicing Events

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