review article | Q7318358 |
scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1036364878 |
P356 | DOI | 10.1134/S0006297916020012 |
P698 | PubMed publication ID | 27260387 |
P2093 | author name string | A V Kulikov | |
B D Zhivotovsky | |||
V G Gogvadze | |||
P V Maximchik | |||
P2860 | cites work | Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria | Q22008484 |
Hallmarks of Cancer: The Next Generation | Q22252312 | ||
Reactive oxygen species mediate caspase activation and apoptosis induced by lipoic acid in human lung epithelial cancer cells through Bcl-2 down-regulation | Q23914984 | ||
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function | Q24293924 | ||
Hexokinase II: cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria | Q24595940 | ||
Understanding the Warburg effect: the metabolic requirements of cell proliferation | Q24604760 | ||
Hexokinase II detachment from the mitochondria potentiates cisplatin induced cytotoxicity through a caspase-2 dependent mechanism | Q24634709 | ||
Determinants of BH3 Binding Specificity for Mcl-1 versus Bcl-xL | Q27660407 | ||
p53 regulates mitochondrial respiration | Q28242400 | ||
Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt | Q28255373 | ||
Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis | Q28283313 | ||
A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth | Q28283339 | ||
Energy metabolism in tumor cells | Q28288377 | ||
Regulation of cancer cell metabolism | Q28303890 | ||
Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak | Q28572925 | ||
The pathophysiology of mitochondrial cell death | Q29547893 | ||
Absolute oxygen tension (pO(2)) in murine fatty and muscle tissue as determined by EPR. | Q47694426 | ||
Decreased affinity for oxygen of cytochrome-c oxidase in Leigh syndrome caused by SURF1 mutations | Q47952796 | ||
Oxidative metabolism and glycolysis in benign brain tumors | Q48216195 | ||
The energy blockers 3-bromopyruvate and lonidamine: effects on bioenergetics of brain mitochondria | Q48560205 | ||
Acetoacetate metabolism in AS-30D hepatoma cells. | Q51594509 | ||
Bid, but not Bax, regulates VDAC channels. | Q53849605 | ||
On the mechanism of the crabtree effect in mouse ascites tumor cells | Q67014148 | ||
Role of acetoin on the regulation of intermediate metabolism of Ehrlich ascites tumor mitochondria: its contribution to membrane cholesterol enrichment modifying passive proton permeability | Q68656978 | ||
Regulation of cellular energy metabolism: the Crabtree effect | Q71259962 | ||
Understanding the dynamics of cellular responsiveness to modifications of metabolic substrates in perifusion | Q72037241 | ||
Occurrence of the Crabtree effect in HeLa cells | Q74687772 | ||
Tumor hypoxia and gene expression--implications for malignant progression and therapy | Q77709035 | ||
Mitochondria in cancer | Q80066603 | ||
Glycolysis inhibition targets Mcl-1 to restore sensitivity of lymphoma cells to ABT-737-induced apoptosis | Q82468263 | ||
The combination of metformin and 2-deoxyglucose inhibits autophagy and induces AMPK-dependent apoptosis in prostate cancer cells | Q95804869 | ||
Greater cell cycle inhibition and cytotoxicity induced by 2-deoxy-d-glucose in tumor cells treated under hypoxic vs aerobic conditions | Q44647527 | ||
A novel Bim-BH3-derived Bcl-XL inhibitor: biochemical characterization, in vitro, in vivo and ex-vivo anti-leukemic activity | Q45357282 | ||
Immuno- and hepato-toxicity of dichloroacetic acid in MRL(+/+) and B(6)C(3)F(1) mice | Q46287362 | ||
Inhibition of energy-producing pathways of HepG2 cells by 3-bromopyruvate | Q46302698 | ||
Glucose metabolism heterogeneity in human and mouse malignant glioma cell lines | Q46727509 | ||
Aerobic glycolysis: meeting the metabolic requirements of cell proliferation | Q29615178 | ||
Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction | Q29616653 | ||
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism | Q29617213 | ||
Spatial heterogeneity and oxygen dependence of glucose consumption in R3230Ac and fibrosarcomas of the Fischer 344 rat. | Q33217203 | ||
Oncogenic alterations of metabolism | Q33546892 | ||
Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria | Q33959022 | ||
BH3 mimetics: status of the field and new developments | Q34037924 | ||
Targeting mitochondria for cancer therapy | Q34115304 | ||
Nitric oxide inhibition of respiration involves both competitive (heme) and noncompetitive (copper) binding to cytochrome c oxidase | Q34270791 | ||
Energy substrate modulates mitochondrial structure and oxidative capacity in cancer cells | Q34297004 | ||
Hexokinase 1 blocks apoptotic signals at the mitochondria | Q34369759 | ||
Effect of extracellular AMP on cell proliferation and metabolism of breast cancer cell lines with high and low glycolytic rates | Q34416216 | ||
3-Thiomorpholin-8-oxo-8H-acenaphtho [1,2-b] pyrrole-9-carbonitrile (S1) derivatives as pan-Bcl-2-inhibitors of Bcl-2, Bcl-xL and Mcl-1. | Q34498717 | ||
Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells. | Q34645070 | ||
Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane | Q34647032 | ||
Mitochondrial intermembrane junctional complexes and their involvement in cell death | Q34648830 | ||
Hypoxia-inducible factor-1alpha and the glycolytic phenotype in tumors. | Q34768392 | ||
BCL-2 family antagonists for cancer therapy | Q34891196 | ||
Multiple BH3 mimetics antagonize antiapoptotic MCL1 protein by inducing the endoplasmic reticulum stress response and up-regulating BH3-only protein NOXA. | Q35107469 | ||
PI3K/Akt and apoptosis: size matters | Q35603373 | ||
Cancer metabolism: facts, fantasy, and fiction | Q35617179 | ||
The TCA cycle and tumorigenesis: the examples of fumarate hydratase and succinate dehydrogenase. | Q35622053 | ||
Deviant energetic metabolism of glycolytic cancer cells | Q35653177 | ||
Tumor Mitochondria and the Bioenergetics of Cancer Cells | Q35681852 | ||
Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production | Q35748754 | ||
Stressing out over survival: glutamine as an apoptotic modulator. | Q36254208 | ||
The role of the mitochondrial permeability transition in cell death | Q36578744 | ||
Rheostat control of gene expression by metabolites | Q36612424 | ||
Glucose metabolism and cancer | Q36625786 | ||
Mitochondria-targeted drugs synergize with 2-deoxyglucose to trigger breast cancer cell death | Q36979129 | ||
Mitocans: mitochondrial targeted anti-cancer drugs as improved therapies and related patent documents | Q37066949 | ||
Mitochondria in cancer cells: what is so special about them? | Q37093125 | ||
Alpha-tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II. | Q37158312 | ||
Regulation of hexokinase binding to VDAC | Q37235994 | ||
Roles of p53, MYC and HIF-1 in regulating glycolysis - the seventh hallmark of cancer | Q37259237 | ||
Metabolic transformation in cancer. | Q37423585 | ||
Proapoptotic N-truncated BCL-xL protein activates endogenous mitochondrial channels in living synaptic terminals | Q37535121 | ||
Pyruvate into lactate and back: from the Warburg effect to symbiotic energy fuel exchange in cancer cells. | Q37552177 | ||
The Warburg effect and mitochondrial stability in cancer cells | Q37648867 | ||
Bioenergetic pathways in tumor mitochondria as targets for cancer therapy and the importance of the ROS-induced apoptotic trigger | Q37660632 | ||
Rethinking the Warburg effect with Myc micromanaging glutamine metabolism | Q37677940 | ||
The pivotal roles of mitochondria in cancer: Warburg and beyond and encouraging prospects for effective therapies | Q37728362 | ||
Waves of gene regulation suppress and then restore oxidative phosphorylation in cancer cells | Q37749030 | ||
Mitochondrially targeted anti-cancer agents | Q37769939 | ||
Oxidative phosphorylation in cancer cells | Q37789810 | ||
Choosing between glycolysis and oxidative phosphorylation: A tumor's dilemma? | Q37801026 | ||
Pro-apoptotic activity of BH3-only proteins and BH3 mimetics: from theory to potential cancer therapy | Q37977487 | ||
Many players in BCL-2 family affairs | Q38185804 | ||
Small molecule Mcl-1 inhibitors for the treatment of cancer | Q38244767 | ||
Mitochondrial substrates in cancer: drivers or passengers? | Q38245420 | ||
Mitochondrially targeted vitamin E succinate modulates expression of mitochondrial DNA transcripts and mitochondrial biogenesis | Q38921197 | ||
Why to compare absolute numbers of mitochondria. | Q38980806 | ||
3-Bromopyruvate induces apoptosis in breast cancer cells by downregulating Mcl-1 through the PI3K/Akt signaling pathway | Q39027590 | ||
Targeting cisplatin-resistant human tumor cells with metabolic inhibitors | Q39042043 | ||
Impact of 2-deoxy-D-glucose on the target metabolome profile of a human endometrial cancer cell line | Q39067055 | ||
Glutamine deprivation enhances antitumor activity of 3-bromopyruvate through the stabilization of monocarboxylate transporter-1. | Q39317923 | ||
The BH3 mimetic S1 induces autophagy through ER stress and disruption of Bcl-2/Beclin 1 interaction in human glioma U251 cells | Q39349641 | ||
Targeting mitochondria by α-tocopheryl succinate kills neuroblastoma cells irrespective of MycN oncogene expression | Q39404881 | ||
Targeting cancer cell metabolism: the combination of metformin and 2-deoxyglucose induces p53-dependent apoptosis in prostate cancer cells | Q39730167 | ||
Inhibition of glycolysis enhances cisplatin-induced apoptosis in ovarian cancer cells | Q39742722 | ||
The role of high rates of glycolysis and glutamine utilization in rapidly dividing cells | Q39826882 | ||
Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c. | Q39912742 | ||
Mitochondrial-targeted active Akt protects SH-SY5Y neuroblastoma cells from staurosporine-induced apoptotic cell death | Q39961067 | ||
Increased ROS generation and p53 activation in alpha-lipoic acid-induced apoptosis of hepatoma cells. | Q40202620 | ||
pO2- and pH-gradients in multicellular spheroids and their relationship to cellular metabolism and radiation sensitivity of malignant human tumor cells. | Q40647638 | ||
Characterization of porin isoforms expressed in tumor cells | Q40853637 | ||
Glucose and phosphate inhibit respiration and oxidative metabolism in cultured hamster eight-cell embryos: evidence for the "crabtree effect". | Q41171991 | ||
VDAC closure increases calcium ion flux | Q41816375 | ||
The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized. | Q42064781 | ||
Apoptosis of B-cell chronic lymphocytic leukemia cells induced by a novel BH3 peptidomimetic | Q42448236 | ||
Oxidative phosphorylation is impaired by prolonged hypoxia in breast and possibly in cervix carcinoma | Q42960308 | ||
Akt activation protects hippocampal neurons from apoptosis by inhibiting transcriptional activity of p53. | Q43508981 | ||
Cytochrome c release occurs via Ca2+-dependent and Ca2+-independent mechanisms that are regulated by Bax. | Q43551075 | ||
Multisite control of the Crabtree effect in ascites hepatoma cells. | Q43572428 | ||
Role of protonatable groups of bovine heart bc(1) complex in ubiquinol binding and oxidation | Q43808628 | ||
Bcl-2 and Bax regulate the channel activity of the mitochondrial adenine nucleotide translocator | Q44273379 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 65-79 | |
P577 | publication date | 2016-02-01 | |
P1433 | published in | Biochemistry | Q4086944 |
P1476 | title | Cellular Energetics as a Target for Tumor Cell Elimination | |
P478 | volume | 81 |
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