Proapoptotic N-truncated BCL-xL protein activates endogenous mitochondrial channels in living synaptic terminals

scholarly article

Proapoptotic N-truncated BCL-xL protein activates endogenous mitochondrial channels in living synaptic terminals is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2004PNAS..10113590J
P356DOI10.1073/PNAS.0401372101
P932PMC publication ID518799
P698PubMed publication ID15342906
P5875ResearchGate publication ID8369551

P2093author name stringElizabeth A Jonas
Leonard K Kaczmarek
J Marie Hardwick
Iva Ivanovska
Gorka Basañez
Joshua Zimmerberg
Kathleen W Kinnally
John A Hickman
Brian M Polster
Teresa A Brandt
Mushtaque Chachar
Yihru Fannjiang
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Modulation of synaptic transmission by the BCL-2 family protein BCL-xL.Q44580813
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Patch clamping VDAC in liposomes containing whole mitochondrial membranesQ67708793
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Pro-apoptotic cleavage products of Bcl-xL form cytochrome c-conducting pores in pure lipid membranesQ74001282
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Caspase-3-dependent cleavage of Bcl-2 promotes release of cytochrome cQ78010472
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptorsQ24310559
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosisQ24310597
bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell deathQ24312157
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X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell deathQ27733156
Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosisQ27734734
Import of proteins into mitochondria. Cytochrome b2 and cytochrome c peroxidase are located in the intermembrane space of yeast mitochondriaQ27935509
Multicopy suppressors of phenotypes resulting from the absence of yeast VDAC encode a VDAC-like proteinQ27937552
VDAC, a channel in the outer mitochondrial membraneQ28286293
bcl-x is expressed in embryonic and postnatal neural tissues and functions to prevent neuronal cell deathQ28513006
Characterization of the signal that directs Bcl-x(L), but not Bcl-2, to the mitochondrial outer membraneQ28580739
VDAC2 inhibits BAK activation and mitochondrial apoptosisQ28594000
Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membraneQ29616354
Modulation of a calcium-sensitive nonspecific cation channel by closely associated protein kinase and phosphatase activitiesQ30454273
Mechanisms underlying hypoxia-induced neuronal apoptosisQ33935219
Multiple conductance channel activity of wild-type and voltage-dependent anion-selective channel (VDAC)-less yeast mitochondriaQ34129593
VDAC regulation by the Bcl-2 family of proteinsQ34139328
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Breaking the mitochondrial barrierQ34286380
Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membraneQ34647032
BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and BakQ35079498
Outer mitochondrial membrane permeability can regulate coupled respiration and cell survivalQ35690379
Modulation of cell death by Bcl-XL through caspase interactionQ35739439
Bcl-xL protects adult septal cholinergic neurons from axotomized cell deathQ35931272
Bax-induced cytochrome C release from mitochondria is independent of the permeability transition pore but highly dependent on Mg2+ ionsQ36255553
Bax, but not Bcl-xL, decreases the lifetime of planar phospholipid bilayer membranes at subnanomolar concentrationsQ36353924
Caspase cleavage enhances the apoptosis-inducing effects of BAD.Q39458955
Mutagenesis of the BH3 domain of BAX identifies residues critical for dimerization and killingQ39576297
Cleavage of Bax enhances its cell death functionQ40885560
Conversion of Bcl-2 to a Bax-like death effector by caspasesQ41073693
Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosisQ42004487
MAS6 encodes an essential inner membrane component of the yeast mitochondrial protein import pathwayQ42111875
Immunohistochemical analysis of in vivo patterns of Bcl-X expressionQ42491717
BH3 death domain peptide induces cell type-selective mitochondrial outer membrane permeabilityQ43694405
P433issue37
P407language of work or nameEnglishQ1860
P921main subjectmitochondrionQ39572
P1104number of pages6
P304page(s)13590-13595
P577publication date2004-09-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleProapoptotic N-truncated BCL-xL protein activates endogenous mitochondrial channels in living synaptic terminals
P478volume101

Reverse relations

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