Neuroprotective effect of lidocaine: is there clinical potential?

scientific article

Neuroprotective effect of lidocaine: is there clinical potential? is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P932PMC publication ID4859874
P698PubMed publication ID27186318

P2093author name stringJun Lin
Tiandong Leng
Xiuren Gao
James P Dilger
P2860cites workCerebral protection by lidocaine during cardiac operationsQ48216002
Intravenous antiarrhythmic doses of lidocaine increase the survival rate of CA1 neurons and improve cognitive outcome after transient global cerebral ischemia in ratsQ48246040
Cerebral protection by lidocaine during cardiac operations: a follow-up studyQ48447016
The effect of lidocaine on early postoperative cognitive dysfunction after coronary artery bypass surgeryQ49023484
Lidocaine prolongs the safe duration of circulatory arrest during deep hypothermia in dogs.Q51503939
The importance of sodium for anoxic transmission damage in rat hippocampal slices: mechanisms of protection by lidocaine.Q51585599
Damage from oxygen and glucose deprivation in hippocampal slices is prevented by tetrodotoxin, lidocaine and phenytoin without blockade of action potentials.Q51619927
Continuous lidocaine infusion and focal feline cerebral ischemia.Q51741984
Meta-analytic evidence against prophylactic use of lidocaine in acute myocardial infarction.Q51744873
Effect of lidocaine after experimental cerebral ischemia induced by air embolism.Q51758459
The effect of intravenous lidocaine on experimental brain edema and neural activities.Q51763724
The effects of a prophylactic bolus of lidocaine in focal cerebral ischaemia.Q51768297
Effect of intravenous lidocaine on experimental spinal cord injury.Q51847842
Protective effect of lidocaine in acute cerebral ischemia induced by air embolism.Q51848363
Lidocaine for reducing propofol-induced pain on induction of anaesthesia in adultsQ24186126
Prophylactic lidocaine for myocardial infarctionQ24187816
Pharmacological perioperative brain neuroprotection: a qualitative review of randomized clinical trialsQ27016568
Long-term postoperative cognitive dysfunction in the elderly ISPOCD1 study. ISPOCD investigators. International Study of Post-Operative Cognitive DysfunctionQ28266358
Delayed treatment with lidocaine reduces mouse microglial cell injury and cytokine production after stimulation with lipopolysaccharide and interferon γ.Q30420168
A brief review of innovative uses for local anestheticsQ30446881
Effects of delayed administration of low-dose lidocaine on transient focal cerebral ischemia in ratsQ30872384
The clinical pharmacology of lidocaine as an antiarrhythymic drugQ34214645
Neuroprotection in ischemia: blocking calcium-permeable acid-sensing ion channels.Q34348555
Cytotoxicity of local anesthetics in human neuronal cellsQ34947470
Trends in Door-to-Thrombolysis Time in the Safe Implementation of Stroke Thrombolysis Registry: Effect of Center Volume and Duration of Registry Membership.Q35591355
Neuroprotection in cerebral ischaemia: facts and fancies--the need for new approachesQ35615757
Inhibition of acid sensing ion channel currents by lidocaine in cultured mouse cortical neuronsQ36070252
Randomized, double-blinded, placebo controlled study of neuroprotection with lidocaine in cardiac surgeryQ37032255
The use of lidocaine as an anti-inflammatory substance: a systematic review.Q37342000
Postoperative delirium and cognitive dysfunctionQ37470591
A key role for TRPM7 channels in anoxic neuronal deathQ40603687
Adverse neurologic events: risks of intracardiac versus extracardiac surgeryQ40961123
Lidocaine Did Not Reduce Neuropsychological-Cognitive Decline in Patients 6 Months After Supratentorial Tumor Surgery: A Randomized, Controlled TrialQ41662833
Lidocaine accelerates neuroelectrical recovery after incomplete global ischemia in rabbitsQ43418075
Neuroprotective effect of low-dose lidocaine in a rat model of transient focal cerebral ischemiaQ43707757
Sodium influx blockade and hypoxic damage to CA1 pyramidal neurons in rat hippocampal slicesQ43814471
Lidocaine attenuates apoptosis in the ischemic penumbra and reduces infarct size after transient focal cerebral ischemia in ratsQ44852860
Local anesthetic lidocaine inhibits TRPM7 current and TRPM7-mediated zinc toxicityQ44853137
Neuroprotective mechanisms of lidocaine against in vitro ischemic insult of the rat hippocampal CA1 pyramidal neuronsQ46652381
Effects of lignocaine on pressor response to laryngoscopy and endotracheal intubation during general anaesthesia in rigid suspension laryngoscopyQ47775565
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectlidocaineQ216935
P304page(s)9-13
P577publication date2016-01-01
P1476titleNeuroprotective effect of lidocaine: is there clinical potential?
P478volume8

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cites work (P2860)
Q49458929Anesthetic Preconditioning as Endogenous Neuroprotection in Glaucoma
Q64921432Postoperative Cognitive Decline After Cardiac Surgery: A Narrative Review of Current Knowledge in 2019.

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