review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Hiroki Mizukami | |
Soroku Yagihashi | |||
Wataru Inaba | |||
P2860 | cites work | Immunoassay of endogenous plasma insulin in man | Q22306302 |
Significant human beta-cell turnover is limited to the first three decades of life as determined by in vivo thymidine analog incorporation and radiocarbon dating | Q28742133 | ||
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes | Q29615593 | ||
Interleukin-1-receptor antagonist in type 2 diabetes mellitus | Q29619001 | ||
Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes | Q29619192 | ||
β-Cell failure in type 2 diabetes | Q33588325 | ||
Age-associated changes of islet endocrine cells and the effects of body mass index in Japanese | Q33628658 | ||
Ontogeny, differentiation and growth of the endocrine pancreas | Q33985105 | ||
Reduced beta-cell mass and expression of oxidative stress-related DNA damage in the islet of Japanese Type II diabetic patients. | Q53979441 | ||
Resident macrophages mediate islet amyloid polypeptide-induced islet IL-1β production and β-cell dysfunction. | Q54614933 | ||
Cell cycle control of β-cell replication in the prenatal and postnatal human pancreas | Q54638182 | ||
Selective β-Cell Loss and α-Cell Expansion in Patients with Type 2 Diabetes Mellitus in Korea | Q57214866 | ||
Early phase glucagon and insulin secretory abnormalities, but not incretin secretion, are similarly responsible for hyperglycemia after ingestion of nutrients | Q57591270 | ||
Obesity and type 2 diabetes in Japanese patients | Q58207650 | ||
Immunochemical Distinction between Insulins with Identical Amino-Acid Sequences | Q59000512 | ||
Expression of an islet regenerating (reg) gene in isolated rat islets: effects of nutrient and non-nutrient growth factors | Q67534160 | ||
Cellular composition of the human diabetic pancreas | Q70269326 | ||
DNA synthesis in cultured neonatal rat islets — a comparison of two methods | Q71864464 | ||
Quantitation of Endocrine Cell Content in the Pancreas of Nondiabetic and Diabetic Humans | Q72546157 | ||
Quantitative estimation of the pancreatic islet tissue in diabetic subjects | Q73849716 | ||
Macrophages and pancreatic islet amyloidosis | Q74483148 | ||
Involvement of oxidative stress-induced DNA damage, endoplasmic reticulum stress, and autophagy deficits in the decline of β-cell mass in Japanese type 2 diabetic patients | Q87622984 | ||
Paracrinology of islets and the paracrinopathy of diabetes | Q34136529 | ||
Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover | Q34244209 | ||
Islet amyloid with macrophage migration correlates with augmented β-cell deficits in type 2 diabetic patients | Q34336126 | ||
Pancreatic alpha cell mass in European subjects with type 2 diabetes | Q35031657 | ||
Islet amyloid polypeptide demonstrates a persistent capacity to disrupt membrane integrity | Q35034994 | ||
β-cell loss and β-cell apoptosis in human type 2 diabetes are related to islet amyloid deposition | Q35070534 | ||
Human-IAPP disrupts the autophagy/lysosomal pathway in pancreatic β-cells: protective role of p62-positive cytoplasmic inclusions | Q35092842 | ||
Reduced Ki67 Staining in the Postmortem State Calls Into Question Past Conclusions About the Lack of Turnover of Adult Human β-Cells | Q35532309 | ||
Islet amyloid: a complication of islet dysfunction or an aetiological factor in Type 2 diabetes? | Q35628614 | ||
Quo vadis: Where have the β-cells gone? | Q35879292 | ||
Pathophysiologic differences among Asians, native Hawaiians, and other Pacific Islanders and treatment implications | Q35898378 | ||
Formation of a human β-cell population within pancreatic islets is set early in life | Q36201514 | ||
Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure | Q36241895 | ||
β-cell mass and turnover in humans: effects of obesity and aging | Q36477911 | ||
Expansion of beta-cell mass in response to pregnancy | Q36768314 | ||
Beta-cell replication is the primary mechanism subserving the postnatal expansion of beta-cell mass in humans | Q36971500 | ||
Adult diffuse nesidioblastosis: genetically or environmentally induced? | Q37028417 | ||
Amyloid formation in human IAPP transgenic mouse islets and pancreas, and human pancreas, is not associated with endoplasmic reticulum stress | Q37324652 | ||
Insulin resistance alters islet morphology in nondiabetic humans | Q37597046 | ||
Amyloid in the islets of Langerhans: thoughts and some historical aspects | Q37864338 | ||
Longevity of human islet α- and β-cells | Q37913504 | ||
Inflammation in obesity and diabetes: islet dysfunction and therapeutic opportunity. | Q38112934 | ||
Macrophages and islet inflammation in type 2 diabetes | Q38134112 | ||
Down-regulation of pancreatic transcription factors and incretin receptors in type 2 diabetes | Q38174889 | ||
Clinical staging of type 2 diabetes: The time has come | Q39403167 | ||
Participation of Akt, menin, and p21 in pregnancy-induced beta-cell proliferation | Q39793341 | ||
Beta-cell development and turnover during prenatal life in humans | Q39917634 | ||
High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated beta-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes | Q40137823 | ||
Differential volumetry of A,B and D cells in the pancreatic islets of diabetic and nondiabetic subjects | Q41151495 | ||
THE RELATION OE DIABETES MELLITUS TO LESIONS OF THE PANCREAS. HYALINE DEGENERATION OF THE ISLANDS OE LANGERHANS. | Q41786170 | ||
Accelerated loss of islet beta cells in sucrose-fed Goto-Kakizaki rats, a genetic model of non-insulin-dependent diabetes mellitus | Q41810412 | ||
Mechanisms of impaired fasting glucose and glucose intolerance induced by an approximate 50% pancreatectomy | Q42498875 | ||
The determination of blood-sugar: Critical analysis of the reduction of alkaline copper reagents by glucose and other substances | Q42573099 | ||
Prevalence and clinicopathological characteristics of islet amyloid in chinese patients with type 2 diabetes | Q44631818 | ||
Change in β-cell mass in Japanese nondiabetic obese individuals. | Q45984989 | ||
Pancreatic beta-cell mass in European subjects with type 2 diabetes | Q46332814 | ||
Partial pancreatectomy in adult humans does not provoke beta-cell regeneration | Q46932707 | ||
p27 Regulates the transition of beta-cells from quiescence to proliferation | Q46941946 | ||
WHO diagnostic criteria as a validation tool for the diagnosis of diabetes mellitus: a study in five European countries. | Q51489018 | ||
The long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation. | Q51780558 | ||
Type 2 diabetes-a matter of beta-cell life and death? | Q53873519 | ||
P275 | copyright license | Creative Commons Attribution-NonCommercial-NoDerivatives | Q6937225 |
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | pathology | Q7208 |
cell growth | Q189159 | ||
islet of Langerhans | Q728309 | ||
type 2 diabetes | Q3025883 | ||
insulin-secreting cells | Q70229258 | ||
P5008 | on focus list of Wikimedia project | ScienceSource | Q55439927 |
P304 | page(s) | 155-65 | |
P577 | publication date | 2016-03-01 | |
P1433 | published in | Journal of Diabetes Investigation | Q28207066 |
P1476 | title | Dynamic pathology of islet endocrine cells in type 2 diabetes: β-Cell growth, death, regeneration and their clinical implications | |
P478 | volume | 7 |
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Q39069908 | Clinical relevance of epigenetics in the onset and management of type 2 diabetes mellitus |
Q41147348 | Culturing and transcriptome profiling of progenitor-like colonies derived from adult mouse pancreas |
Q57300294 | Effectiveness of Coenzyme Q10 Supplementation for Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis |
Q55394333 | Host-Parasite Interactions in Individuals with Type 1 and 2 Diabetes Result in Higher Frequency of Ascaris lumbricoides and Giardia lamblia in Type 2 Diabetic Individuals. |
Q93029127 | Pancreatic Islet Hyperplasia: A Potential Marker for Anabolic-Androgenic Steroid Use |
Q49795312 | Pancreatic and Islet Remodeling in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Knockout Ferrets |
Q92926186 | Proinsulin is sensitive to reflect glucose intolerance |
Q42876331 | Renoprotective Effects of the Dipeptidyl Peptidase-4 Inhibitor Sitagliptin: A Review in Type 2 Diabetes |
Q64103626 | Repetition of Prediabetes Enhances the Risk of Developing Diabetes |
Q89426717 | Reply to the comment of Wilbrink et al. on Retrospective analysis of liraglutide and basal insulin combination therapy in Japanese type 2 diabetes: The association between remaining β-cell function and the achievement of the HbA1c target 1 year afte |
Q42696994 | Sodium glucose co-transporter 2 inhibitor, tofogliflozin, shows better improvements of blood glucose and insulin secretion in patients with high insulin levels at baseline |
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