The Role of the Reactive Oxygen Species and Oxidative Stress in the Pathomechanism of the Age-Related Ocular Diseases and Other Pathologies of the Anterior and Posterior Eye Segments in Adults

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The Role of the Reactive Oxygen Species and Oxidative Stress in the Pathomechanism of the Age-Related Ocular Diseases and Other Pathologies of the Anterior and Posterior Eye Segments in Adults is …
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review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1155/2016/3164734
P3181OpenCitations bibliographic resource ID2210181
P932PMC publication ID4736974
P698PubMed publication ID26881021
P5875ResearchGate publication ID289984613

P50authorAndrzej GrzybowskiQ20029006
Małgorzata NitaQ125100911
P2860cites workReactive species and oxidative stress in optic nerve vulnerable to secondary degeneration.Q46879402
Potential role of A2A adenosine receptor in traumatic optic neuropathyQ46987515
Retinal ganglion cell axotomy induces an increase in intracellular superoxide anion.Q48604572
Oxidative stress and glaucoma: injury in the anterior segment of the eye.Q48875855
Differential production of superoxide by neuronal mitochondriaQ21262044
Accelerated aging in glaucoma: immunohistochemical assessment of advanced glycation end products in the human retina and optic nerve headQ22306304
Autophagy, mitochondria and oxidative stress: cross-talk and redox signallingQ24608960
Oxidative stress, mitochondrial dysfunction, and agingQ24635310
SIRT6 in DNA repair, metabolism and ageingQ24653962
Oxygen and blood flow: players in the pathogenesis of glaucomaQ24654000
The number of people with glaucoma worldwide in 2010 and 2020Q24679554
Oxidative stress induces autophagy in response to multiple noxious stimuli in retinal ganglion cellsQ27024171
Free radicals in the physiological control of cell functionQ27860480
Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domainsQ28114920
Evidence of oxidative stress in human corneal diseasesQ28201957
The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells.Q50511473
Mitochondria induce oxidative stress, generation of reactive oxygen species and redox state unbalance of the eye lens leading to human cataract formation: disruption of redox lens organization by phospholipid hydroperoxides as a common basis for catQ52608791
Alterations of ocular nitric oxide synthase in human glaucoma.Q54005097
Age-Related Macular DegenerationQ54263427
Genetics and clinical characteristics of keratoconusQ54417995
Microsomal Lipid Peroxidation: Morphological CharacterizationQ67274599
Region and age-dependent variation in susceptibility of the human retina to lipid peroxidationQ67964942
Effect of oxidized glutathione on the barrier function of the corneal endotheliumQ67970562
Lipid peroxidation in rod outer segments. Role of hydroxyl radical and lipid hydroperoxidesQ68158782
Lens opacity induced by lipid peroxidation products as a model of cataract associated with retinal diseaseQ69647914
Trabecular meshwork cellularity in primary open-angle glaucoma and nonglaucomatous normalsQ70571024
Over-expression of a gelatinase A activity in keratoconusQ71584147
Glutathione in calf trabecular meshwork and its relation to aqueous humor outflow facilityQ71827897
Light exposure and the risk of cortical, nuclear, and posterior subcapsular cataracts: the Pathologies Oculaires Liées à l'Age (POLA) studyQ73559511
Amyloid and non-amyloid forms of 5q31-linked corneal dystrophy resulting from kerato-epithelin mutations at Arg-124 are associated with abnormal turnover of the proteinQ73643381
Diabetic retinopathyQ75217418
Oxidative stress affects cytoskeletal structure and cell-matrix interactions in cells from an ocular tissue: the trabecular meshworkQ77966075
Expressions of angiopoietins and Tie2 in human choroidal neovascular membranesQ78106435
A comparison of the environment of thiol groups in bovine and human gamma crystallins using raman spectroscopyQ78384926
Protein oxidation and agingQ79336883
Involvement of oxidative stress on corneal epithelial alterations in a blink-suppressed dry eyeQ80050218
Primary open-angle glaucomaQ80122027
The cross-talk between NF-kappaB and HIF-1: further evidence for a significant liaisonQ81324446
Age-related macular degenerationQ81448353
Melatonin protects against oxidative stress in granular corneal dystrophy type 2 corneal fibroblasts by mechanisms that involve membrane melatonin receptorsQ83581018
Coenzyme Q10 prevents human lens epithelial cells from light-induced apoptotic cell death by reducing oxidative stress and stabilizing BAX / Bcl-2 ratioQ84017840
Association of mitochondrial haplogroups H and R with keratoconus in Saudi Arabian patientsQ87659382
The cascade hypothesis of keratoconusQ36319815
Anti-inflammatory properties of sirtuin 6 in human umbilical vein endothelial cellsQ36364263
The role of inflammation in CNS injury and diseaseQ36364424
Epigallocatechin gallate protects against oxidative stress-induced mitochondria-dependent apoptosis in human lens epithelial cellsQ36493008
Oxygen-dependent diseases in the retina: role of hypoxia-inducible factorsQ36496079
Macular pigment: a review of current knowledgeQ36532658
Axons of retinal ganglion cells are insulted in the optic nerve early in DBA/2J glaucomaQ36639100
Glaucomatous outflow pathway and oxidative stress.Q36695696
Nitric oxide and choroidal blood flow regulationQ36698968
A compensatory mechanism protects retinal mitochondria from initial insult in diabetic retinopathyQ36783430
Mechanisms of immune system activation in glaucoma: oxidative stress-stimulated antigen presentation by the retina and optic nerve head gliaQ36808534
Balance between autophagic pathways preserves retinal homeostasisQ36847336
Neuronal and glial cell abnormality as predictors of progression of diabetic retinopathyQ36952309
Glycation and carboxymethyllysine levels in skin collagen predict the risk of future 10-year progression of diabetic retinopathy and nephropathy in the diabetes control and complications trial and epidemiology of diabetes interventions and complicatQ37054987
Oxidative and nitrative stress markers in glaucomaQ37167834
Oxidative stress in normal and impaired wound repairQ37212396
Sulforaphane decreases endothelial cell apoptosis in fuchs endothelial corneal dystrophy: a novel treatment.Q37232070
Oxidative stress in diseases of the human corneaQ37249036
Decreased catalase expression and increased susceptibility to oxidative stress in primary cultured corneal fibroblasts from patients with granular corneal dystrophy type II.Q37257164
Mitochondrial DNA damage and its potential role in retinal degenerationQ37291756
Role of antioxidant enzymes and small molecular weight antioxidants in the pathogenesis of age-related macular degeneration (AMD)Q37298565
Oxidative damage-induced inflammation initiates age-related macular degeneration.Q37357471
Role of nitric oxide, superoxide, peroxynitrite and PARP in diabetic retinopathyQ37410533
Heat shock proteins as gatekeepers of proteolytic pathways-Implications for age-related macular degeneration (AMD).Q37411023
Decreased expression of peroxiredoxins in Fuchs' endothelial dystrophy.Q37412775
Autophagy and human diseasesQ37429062
Advanced glycation end products in extracellular matrix proteins contribute to the failure of sensory nerve regeneration in diabetesQ37429192
Inner retinal ischaemia: current understanding and needs for further investigations.Q37470736
Regulatory role of HIF-1alpha in the pathogenesis of age-related macular degeneration (AMD).Q37546290
The 2-oxoacid dehydrogenase complexes in mitochondria can produce superoxide/hydrogen peroxide at much higher rates than complex IQ37653268
Macular edema. General pathophysiology.Q37779445
AGEs and diabetic retinopathy.Q37793745
Age-related macular degeneration (AMD): Alzheimer's disease in the eye?Q37836251
Mitochondrial reactive oxygen species drive proinflammatory cytokine productionQ37847792
HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxiaQ28300406
Cardiolipin deficiency leads to decreased cardiolipin peroxidation and increased resistance of cells to apoptosisQ28389113
Calpain-mediated cleavage of Beclin-1 and autophagy deregulation following retinal ischemic injury in vivoQ28566495
Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxiaQ28586744
The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alphaQ28588941
Signal transduction by reactive oxygen speciesQ29615230
The pathobiology of diabetic complications: a unifying mechanismQ29617766
Structure and function of matrix metalloproteinases and TIMPsQ30014818
Diabetic retinopathy: seeing beyond glucose-induced microvascular disease.Q30356505
Type 2 diabetes across generations: from pathophysiology to prevention and managementQ30404232
Mitochondrial dysfunction and oxidative stress in Parkinson's disease.Q30444758
Current surgical options for keratoconusQ30901887
Concomitant effect of topical ubiquinone Q10 and vitamin E to prevent keratocyte apoptosis after excimer laser photoablation in rabbits.Q31047719
Depth and age-dependent distribution of keratocytes in healthy human corneas: a study using scanning-slit confocal microscopy in vivoQ31048615
Reduced foveolar choroidal blood flow in eyes with increasing AMD severityQ31149680
Oxygen distribution and consumption within the retina in vascularised and avascular retinas and in animal models of retinal diseaseQ31926355
Foveolar choroidal circulation and choroidal neovascularization in age-related macular degenerationQ33313067
Polymorphisms in COL4A3 and COL4A4 genes associated with keratoconusQ33552075
Neurodegenerative influence of oxidative stress in the retina of a murine model of diabetesQ33773287
Mitochondrial damage in the trabecular meshwork occurs only in primary open-angle glaucoma and in pseudoexfoliative glaucomaQ33809220
Structural characterization of bisretinoid A2E photocleavage products and implications for age-related macular degenerationQ33842052
The sites and topology of mitochondrial superoxide productionQ33888976
The genetics of keratoconusQ33956722
Oxidative stress in keratoconus?Q34039265
Oxidative stress: implications for the development of diabetic retinopathy and antioxidant therapeutic perspectives.Q34081808
The biology of the receptor for advanced glycation end products and its ligandsQ34100112
Vasospasm, its role in the pathogenesis of diseases with particular reference to the eye.Q34207821
Evidence of oxidative stress in the pathogenesis of fuchs endothelial corneal dystrophy.Q34254400
Increased levels of catalase and cathepsin V/L2 but decreased TIMP-1 in keratoconus corneas: evidence that oxidative stress plays a role in this disorderQ34397200
Photo-oxidation of proteins and its role in cataractogenesis.Q34421881
Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid beta-peptideQ34456855
DNA damage and base excision repair in mitochondria and their role in aging.Q34479569
Oxidative DNA damage and total antioxidant status in glaucoma patientsQ34493838
Oxidative stress and neurodegeneration in prion diseasesQ34497458
Damaged mitochondrial DNA replication system and the development of diabetic retinopathyQ36001839
Mitochondria impairment correlates with increased sensitivity of aging RPE cells to oxidative stressQ36024307
Understanding age-related macular degeneration (AMD): relationships between the photoreceptor/retinal pigment epithelium/Bruch's membrane/choriocapillaris complexQ36083881
RPE lipofuscin and its role in retinal pathobiologyQ36111032
Age-related nuclear cataract-oxidation is the key.Q36111043
Reactive oxygen species in the control of hypoxia-inducible factor-mediated gene expression.Q36132882
Breaking barriers: insight into the pathogenesis of neovascular age-related macular degenerationQ36178019
Lens epithelial cell apoptosis appears to be a common cellular basis for non-congenital cataract development in humans and animalsQ36235809
Protein aggregation, metals and oxidative stress in neurodegenerative diseasesQ36295336
The pleiotropic role of autophagy: from protein metabolism to bactericide.Q36296171
Incidence of cystoid macular oedema in diabetic patients after phacoemulsification and free radical link to its pathogenesisQ45198101
Systemic reduction in glutathione levels occurs in patients with primary open-angle glaucomaQ45280860
Sensitivity of ocular anterior chamber tissues to oxidative damage and its relevance to the pathogenesis of glaucoma.Q45974184
Relationship between glyco-oxidation, antioxidant status and microalbuminuria in type 2 diabetic patients.Q46032762
Endoplasmic reticulum stress induced by oxidative stress in retinal pigment epithelial cellsQ46173130
Secondary degeneration of the optic nerve following partial transection: the benefits of lomerizineQ46177834
The evaluation of the oxidative stress parameters in nondiabetic and diabetic senile cataract patients.Q46266103
Effect of lutein on retinal neurons and oxidative stress in a model of acute retinal ischemia/reperfusionQ46308372
Accumulation of mitochondrial DNA damage in keratoconus corneas.Q46337164
Protective effect of ascorbic Acid against corneal damage by ultraviolet B irradiation: a pilot studyQ46413411
Oxidative DNA damage in the human trabecular meshwork: clinical correlation in patients with primary open-angle glaucoma.Q46433031
Hyperoxia and thyroxine treatment and the relationships between reactive oxygen species generation, mitochondrial membrane potential, and cardiolipin in human lens epithelial cell culturesQ46502339
Effects of different types of oxidative stress in RPE cellsQ46555871
Hypersensitive response to oxidative stress in keratoconus corneal fibroblastsQ46564957
Neuroprotective effect of sulfhydryl reduction in a rat optic nerve crush model.Q46722440
Mitochondrial DNA copy number, but not haplogroup is associated with keratoconus in Han Chinese populationQ46783470
Inhibition of adenosine kinase attenuates inflammation and neurotoxicity in traumatic optic neuropathy.Q46805659
Traumatic optic neuropathy: an evolving understandingQ37870252
Inflammation in diabetic retinopathyQ37884176
Proliferative capacity of corneal endothelial cellsQ37929952
Neural degeneration in the retina of the streptozotocin-induced type 1 diabetes modelQ37965160
Corneal collagen cross-linking: an introduction and literature reviewQ37966299
Reactive oxygen species (ROS)--a family of fate deciding molecules pivotal in constructive inflammation and wound healing.Q38046135
Potential of epigenetic mechanisms in AMD pathologyQ38070599
Reactive oxygen species, Nox and angiotensin II in angiogenesis: implications for retinopathyQ38078985
Insights into keratoconus from a genetic perspectiveQ38079593
Nox4 and diabetic nephropathy: with a friend like this, who needs enemies?Q38092960
AGEs, rather than hyperglycemia, are responsible for microvascular complications in diabetes: a "glycoxidation-centric" point of viewQ38115856
Age-related macular degeneration and changes in the extracellular matrixQ38221023
Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysisQ38358203
Histologic analysis of photochemical lesions produced in rhesus retina by short-wave-length lightQ38537823
Heritability of cilioretinal arteries: a twin studyQ39731257
Reactive oxygen species mediate a cellular 'memory' of high glucose stress signallingQ40131838
Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2.Q40179972
Glutathione depletion in antioxidant defense of differentiated NT2-LHON cybridsQ40196311
Glycation-induced inactivation of antioxidant enzymes and modulation of cellular redox status in lens cellsQ40244655
Nitric oxide: a physiologic messenger moleculeQ40394921
Aqueous humor stimulates the migration of human trabecular meshwork cells in vitroQ40831899
Age-related macular degeneration in the aspect of chronic low-grade inflammation (pathophysiological parainflammation).Q41856043
Purification and partial characterization of a lutein-binding protein from human retinaQ42025555
Genome-wide expression profile of human trabecular meshwork cultured cells, nonglaucomatous and primary open angle glaucoma tissue.Q42126987
The alpha-secretase-derived N-terminal product of cellular prion, N1, displays neuroprotective function in vitro and in vivoQ42151993
Quantitative assessment of DNA damage directly in lens epithelial cells from senile cataract patientsQ42154213
Oxidative stress, hypoxia, and autophagy in the neovascular processes of age-related macular degeneration.Q42413400
Differential expression of collagen types XVIII/endostatin and XV in normal, keratoconus, and scarred human corneas.Q42493791
Increased stress-induced generation of reactive oxygen species and apoptosis in human keratoconus fibroblasts.Q42493920
Influence of oxygen free radicals on the tone of ciliary arteries: a model of vasospasms of ocular vasculatureQ42610117
Optic neuropathy induced by reductions in mitochondrial superoxide dismutaseQ42804864
Oxidative stress induces endothelial cell senescence via downregulation of Sirt6.Q42819649
Induction of IL-6 expression by mechanical stress in the trabecular meshworkQ42859421
Sustained stress response after oxidative stress in trabecular meshwork cellsQ42870720
A new insight into the cellular regulation of aqueous outflow: how trabecular meshwork endothelial cells drive a mechanism that regulates the permeability of Schlemm's canal endothelial cellsQ43006718
Mitochondrial damage in the trabecular meshwork of patients with glaucoma.Q43023445
Prevention of UV-induced damage to the anterior segment using class I UV-absorbing hydrogel contact lenses.Q43285277
Involvement of oxidative mechanisms in blue-light-induced damage to A2E-laden RPE.Q43940061
"Unscheduled" DNA synthesis in lens epithelium following ultraviolet irradiationQ44129523
Cell sorting experiments link persistent mitochondrial DNA damage with loss of mitochondrial membrane potential and apoptotic cell deathQ44211070
SOD2 knockdown mouse model of early AMD.Q44260720
Mechanisms of ocular toxicity using the in vitro bovine lens and sodium dodecyl sulfate as a chemical model.Q44406878
DNA Is a Target of the Photodynamic Effects Elicited in A2E-Laden RPE by Blue-Light IlluminationQ44417333
Oxidative stress markers in aqueous humor of glaucoma patientsQ44710317
Elements of the nitric oxide pathway can degrade TIMP-1 and increase gelatinase activity.Q44857232
An estimation of the worldwide economic and health burden of visual impairment.Q44872122
Lipid peroxidation products mediate the formation of 8-hydroxydeoxyguanosine in DNAQ45052758
Retinal oxidative stress induced by high intraocular pressureQ45071741
Caspase-independent component of retinal ganglion cell death, in vitroQ45124551
Oestrogens ameliorate mitochondrial dysfunction in Leber's hereditary optic neuropathy.Q34514611
A2E-epoxides damage DNA in retinal pigment epithelial cells. Vitamin E and other antioxidants inhibit A2E-epoxide formationQ34532224
Fuchs endothelial corneal dystrophyQ34624570
Transcript profile of cellular senescence-related genes in Fuchs endothelial corneal dystrophyQ34656965
Interleukin-1alpha downregulates extracellular-superoxide dismutase in human corneal keratoconus stromal cellsQ34659975
Mitochondrial DNA damage as a potential mechanism for age-related macular degenerationQ34701955
Vitamins E and C, beta-carotene, and other carotenoids as antioxidantsQ34719115
Mitochondrial DNA repair and agingQ34994585
Oxidative stress, mitochondrial dysfunction and calcium overload in human lamina cribrosa cells from glaucoma donorsQ35007216
Focus on molecular events in the anterior chamber leading to glaucoma.Q35021454
Genetic polymorphisms of superoxide dismutases, catalase, and glutathione peroxidase in age-related cataractQ35209197
Proposed international clinical diabetic retinopathy and diabetic macular edema disease severity scalesQ35226427
Role of ultraviolet irradiation and oxidative stress in cataract formation-medical prevention by nutritional antioxidants and metabolic agonistsQ35235050
Mitochondrial proteomics of the retinal pigment epithelium at progressive stages of age-related macular degenerationQ35423355
Expression of endoplasmic reticulum stress markers GRP78 and CHOP induced by oxidative stress in blue light-mediated damage of A2E-containing retinal pigment epithelium cells.Q35428964
Mitochondrial biogenesis and the development of diabetic retinopathyQ35457777
Mutation analysis of VSX1 and SOD1 in Iranian patients with keratoconusQ35606654
The susceptibility of the retina to photochemical damage from visible lightQ35624040
p53-regulated increase in oxidative-stress--induced apoptosis in Fuchs endothelial corneal dystrophy: a native tissue modelQ35647348
Oxidative stress in glaucomatous neurodegeneration: mechanisms and consequencesQ35677091
Diabetic retinopathy and damage to mitochondrial structure and transport machineryQ35687928
Morphological changes in keratoconus: pathology or pathogenesis.Q35739730
Molecular bases of corneal endothelial dystrophiesQ35739942
Current concepts in the pathogenesis of age-related macular degenerationQ35743919
Impaired expression of thrombospondin-1 in eyes with age related macular degenerationQ35761496
Glaucoma progression is associated with decreased blood flow velocities in the short posterior ciliary arteryQ35762615
Human glaucoma and neural degeneration in intracranial optic nerve, lateral geniculate nucleus, and visual cortexQ35769429
Oxidative stress and diabetic retinopathyQ35819297
Oxidative DNA damage and disease: induction, repair and significanceQ35876708
Altered stability of mRNAs associated with glaucoma progression in human trabecular meshwork cells following oxidative stressQ35929964
Ultraviolet radiation: cellular antioxidant response and the role of ocular aldehyde dehydrogenase enzymes.Q35974377
Nuclear ferritin in corneal epithelial cells: tissue-specific nuclear transport and protection from UV-damageQ35989966
Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cellsQ36001244
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjecteye diseaseQ3041498
pathogenesisQ372016
reactive oxygen speciesQ424361
keratoconusQ611984
oxidative stressQ898814
Fuchs' endothelial dystrophyQ1464888
corneal dystrophyQ2044949
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)3164734
P577publication date2016-01-10
P1433published inOxidative medicine and cellular longevityQ26840015
P1476titleThe Role of the Reactive Oxygen Species and Oxidative Stress in the Pathomechanism of the Age-Related Ocular Diseases and Other Pathologies of the Anterior and Posterior Eye Segments in Adults
P478volume2016

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cites work (P2860)
Q387554461H NMR-based serum metabolomics reveals erythromycin-induced liver toxicity in albino Wistar rats.
Q927037248-Oxo-7,8-Dihydro-2'-Deoxyguanosine (8-oxodG) and 8-Hydroxy-2'-Deoxyguanosine (8-OHdG) as a Potential Biomarker for Gestational Diabetes Mellitus (GDM) Development
Q41014437A Case-Control Study on the Oxidative Balance of 50% Autologous Serum Eye Drops
Q98613411A Mitochondrial Genome-Wide Association Study of Cataract in a Latino Population
Q92354023A Novel Role of Ascorbic Acid in Anti-Inflammatory Pathway and ROS Generation in HEMA Treated Dental Pulp Stem Cells
Q64101933A Review of Structural and Biomechanical Changes in the Cornea in Aging, Disease, and Photochemical Crosslinking
Q91713954A Review of Various Antioxidant Compounds and their Potential Utility as Complementary Therapy in Multiple Sclerosis
Q90394938A comparison between the effects of ochratoxin A and aristolochic acid on the inflammation and oxidative stress in the liver and kidney of weanling piglets
Q55078338A hypothesis for treating inflammation and oxidative stress with hydrogen sulfide during age-related macular degeneration.
Q91624186A thermodynamically-constrained mathematical model for the kinetics and regulation of NADPH oxidase 2 complex-mediated electron transfer and superoxide production
Q50091811A2E-associated cell death and inflammation in retinal pigmented epithelial cells from human induced pluripotent stem cells.
Q64268877ARPE-19-derived VEGF-containing exosomes promote neovascularization in HUVEC: the role of the melanocortin receptor 5
Q91864307Achyranthes bidentata polypeptides prevent apoptosis by inhibiting the glutamate current in cultured hippocampal neurons
Q92922785Activation of the TRAAK two-pore domain potassium channels in rd1 mice protects photoreceptor cells from apoptosis
Q52730712Anti-inflammatory Activity of β-Carotene, Lycopene and Tri-n-butylborane, a Scavenger of Reactive Oxygen Species.
Q92997555Antioxidant and Anti-Inflammatory Properties of Anthocyanins Extracted from Oryza sativa L. in Primary Dermal Fibroblasts
Q58554131Antioxidant and Oxidative Stress: A Mutual Interplay in Age-Related Diseases
Q91646547Antioxidants and Retinal Diseases
Q92507571Antiproliferative Effect of Elastin-Derived Peptide VGVAPG on SH-SY5Y Neuroblastoma Cells
Q90446470Assessing the Antioxidant Properties of Larrea tridentata Extract as a Potential Molecular Therapy against Oxidative Stress
Q90229793Assessment of Antioxidant and Cytotoxic Activities of Extracts of Dendrobium crepidatum
Q55084525Association of increased levels of plasma tumor necrosis factor alpha with primary open-angle glaucoma.
Q37531877CLOCK Promotes Endothelial Damage by Inducing Autophagy through Reactive Oxygen Species
Q92422872Cannabidiol Regulates the Expression of Keratinocyte Proteins Involved in the Inflammation Process through Transcriptional Regulation
Q99629126Cannabidiol protects keratinocyte cell membranes following exposure to UVB and hydrogen peroxide
Q91612082Carbon-Doped TiO2 Activated by X-Ray Irradiation for the Generation of Reactive Oxygen Species to Enhance Photodynamic Therapy in Tumor Treatment
Q98293147Chemical Transformatioen of Astaxanthin from Haematococcus pluvialis Improves Its Antioxidative and Anti-inflammatory Activities
Q92899164Clinical Role of Epigenetics and Network Analysis in Eye Diseases: A Translational Science Review
Q97882641Cordycepin attenuates Salivary Hypofunction through the Prevention of Oxidative Stress in Human Submandibular Gland Cells
Q64266437Counter effects of Asiaticosids-D through putative neurotransmission on rotenone induced cerebral ganglionic injury in Lumbricus terrestris
Q98771718Crude Cell-Free Extract From Deinococcus radiodurans Exhibit Anticancer Activity by Inducing Apoptosis in Triple-Negative Breast Cancer Cells
Q52647690Dammarane-type triterpene ginsenoside-Rg18 inhibits human non-small cell lung cancer A549 cell proliferation via G1 phase arrest.
Q93155608Dapagliflozin Prevents NOX- and SGLT2-Dependent Oxidative Stress in Lens Cells Exposed to Fructose-Induced Diabetes Mellitus
Q104130763Design and evaluation of ciprofloxacin loaded collagen chitosan oxygenating scaffold for skin tissue engineering
Q37535413Dietary Compound Chrysin Inhibits Retinal Neovascularization with Abnormal Capillaries in db/db Mice
Q61443219Differential effects of N-acetylcysteine on retinal degeneration in two mouse models of normal tension glaucoma
Q59340793Effect of Myricetin on Primary Open-angle Glaucoma
Q64230377Effects and Underlying Mechanisms of Bioactive Compounds on Type 2 Diabetes Mellitus and Alzheimer's Disease
Q47132583Effects of Fuchs uveitis syndrome on the ultrastructure of the anterior lens epithelium: A transmission electron microscopic study
Q57091289Effects of cadmium exposure on expression of glutathione synthetase system genes in Acidithiobacillus ferrooxidans
Q90135282Effects of enalapril and paricalcitol treatment on diabetic nephropathy and renal expressions of TNF-α, p53, caspase-3 and Bcl-2 in STZ-induced diabetic rats
Q92157877Effects of etanercept on the apoptosis of ganglion cells and expression of Fas, TNF-α, caspase-8 in the retina of diabetic rats
Q48300005Electron microscopic evaluation of anterior lens epithelium in patients with idiopathic congenital cataract.
Q49337447Elevated levels of plasma tumor necrosis factor alpha in patients with pseudoexfoliation glaucoma.
Q92662962Embryonic Thermal Manipulation Affects the Antioxidant Response to Post-Hatch Thermal Exposure in Broiler Chickens
Q91768552Eugenol prevents fMLF-induced superoxide anion production in human neutrophils by inhibiting ERK1/2 signaling pathway and p47phox phosphorylation
Q64065677Evaluation of colloidal platinum on cytotoxicity, oxidative stress and barrier permeability across the gut epithelium
Q58803874Evaluation of serum sphingolipids and the influence of genetic risk factors in age-related macular degeneration
Q37476133First insight into the proteome landscape of the porcine short posterior ciliary arteries: Key signalling pathways maintaining physiologic functions
Q90597003Gastroprotective Effects of Fermented Lotus Root against Ethanol/HCl-Induced Gastric Mucosal Acute Toxicity in Rats
Q90642708Gene Expression Profiling of B Cell Lymphoma in Dogs Reveals Dichotomous Metabolic Signatures Distinguished by Oxidative Phosphorylation
Q92861797Genetic Analysis of Four Sexual Differentiation Process Proteins (isp4/SDPs) in Chaetomium thermophilum and Thermomyces lanuginosus Reveals Their Distinct Roles in Development
Q51763045Grape Seed Proanthocyanidin Extract Prevents Ovarian Aging by Inhibiting Oxidative Stress in the Hens.
Q42358229HDAC6 inhibition by tubastatin A is protective against oxidative stress in a photoreceptor cell line and restores visual function in a zebrafish model of inherited blindness
Q64982077Hepatic DNA Damage Induced by Electronic Cigarette Exposure Is Associated With the Modulation of NAD+/PARP1/SIRT1 Axis.
Q92696488Hepatoprotective effect of silver nanoparticles synthesized using aqueous leaf extract of Rhizophora apiculata
Q92860000Hydrogen Gas in Cancer Treatment
Q98566248Hyperoxia affects the lung tissue: A porcine histopathological and metabolite study using five hours of apneic oxygenation
Q91646668Hypoxia-Induced Degenerative Protein Modifications Associated with Aging and Age-Associated Disorders
Q92404834IL-1 Family Members Mediate Cell Death, Inflammation and Angiogenesis in Retinal Degenerative Diseases
Q100518818Immunopathological features of air pollution and its impact on inflammatory airway diseases (IAD)
Q38769454Impact of reactive oxygen species generation on Helicobacter pylori-related extragastric diseases: a hypothesis.
Q92550183Impairment of Mitochondrial-Nuclear Cross Talk in Lymphocytes Exposed to Landfill Leachate
Q92157021Increased Plasma Levels of 8-Hydroxy-2'-deoxyguanosine (8-OHdG) in Patients with Pseudoexfoliation Glaucoma
Q55424095Inflammatory and cytotoxic effects of bifenthrin in primary microglia and organotypic hippocampal slice cultures.
Q90565894Inhibiting microRNA-144 potentiates Nrf2-dependent antioxidant signaling in RPE and protects against oxidative stress-induced outer retinal degeneration
Q90134529Inhibition of JNJ-26481585-mediated autophagy induces apoptosis via ROS activation and mitochondrial membrane potential disruption in neuroblastoma cells
Q38798527Inhibition of malic enzyme 1 disrupts cellular metabolism and leads to vulnerability in cancer cells in glucose-restricted conditions
Q41233506Inhibitory effect of ethanol extract of Nannochloropsis oceanica on lipopolysaccharide-induced neuroinflammation, oxidative stress, amyloidogenesis and memory impairment
Q39039446Integrated Approaches to Drug Discovery for Oxidative Stress-Related Retinal Diseases.
Q52681162Intravitreal Stanniocalcin-1 Enhances New Blood Vessel Growth in a Rat Model of Laser-Induced Choroidal Neovascularization.
Q33573617Involvement of Nrf2 in Ocular Diseases
Q91712082Karrikin Improves Osmotic and Salt Stress Tolerance via the Regulation of the Redox Homeostasis in the Oil Plant Sapium sebiferum
Q92454573Lycopene Modulates Pathophysiological Processes of Non-Alcoholic Fatty Liver Disease in Obese Rats
Q46288090Melatonin application in targeting oxidative-induced liver injuries: A review
Q28078927Melatonin in Retinal Physiology and Pathology: The Case of Age-Related Macular Degeneration
Q32186021Mesenchymal stem cells attenuate hydrogen peroxide-induced oxidative stress and enhance neuroprotective effects in retinal ganglion cells
Q92429255Mitochondrial dysfunction in human primary alveolar type II cells in emphysema
Q64950657Mitochondrial electron transport chain, ROS generation and uncoupling (Review).
Q91875897Molecular Mechanism of Cytotoxicity, Genotoxicity, and Anticancer Potential of Green Gold Nanoparticles on Human Liver Normal and Cancerous Cells
Q92588999Molecular Mechanisms of Zinc as a Pro-Antioxidant Mediator: Clinical Therapeutic Implications
Q91674977N-Acetyl cysteine ameliorates hyperglycemia-induced cardiomyocyte toxicity by improving mitochondrial energetics and enhancing endogenous Coenzyme Q9/10 levels
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Q92925020Novel fluorine-containing chiral hydrazide-hydrazones: Design, synthesis, structural elucidation, antioxidant and anticholinesterase activity, and in silico studies
Q90163588Ocular toxicity of intravitreal Golimumab in a rabbit model
Q46247554Oxidative Stress in the Development of Genetic Generalised Epilepsy: An Observational Study in Southern Indian Population
Q91646409Oxidative Stress-Induced Pentraxin 3 Expression Human Retinal Pigment Epithelial Cells is Involved in the Pathogenesis of Age-Related Macular Degeneration
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Q90074733Potent Impact of Plastic Nanomaterials and Micromaterials on the Food Chain and Human Health
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Q92066735Quantitative analysis by reversed-phase high-performance liquid chromatography and retinal neuroprotection after topical administration of moxonidine
Q92850032RNA-Seq analysis revealed genes associated with UV-induced cell necrosis through MAPK/TNF-α pathways in human dermal fibroblast cells as an inducer of premature photoaging
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Q89623750Recent Advances in Fluorescent Probes for Detection of HOCl and HNO
Q46246399Resveratrol Prevents ROS-Induced Apoptosis in High Glucose-Treated Retinal Capillary Endothelial Cells via the Activation of AMPK/Sirt1/PGC-1α Pathway.
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Q93005137Rosmarinic and Sinapic Acids May Increase the Content of Reduced Glutathione in the Lenses of Estrogen-Deficient Rats
Q92064949Screening for Novel LOX and SOD1 Variants in Keratoconus Patients from Brazil
Q41694174Selective cytotoxicity of vanadium complexes on human pancreatic ductal adenocarcinoma cell line by inducing necroptosis, apoptosis and mitotic catastrophe process.
Q92825632Short-Term Betanin Intake Reduces Oxidative Stress in Wistar Rats
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Q90448222Stronger antioxidant enzyme immunoreactivity of Populus tomentiglandulosa extract than ascorbic acid in rat liver and kidney
Q91739424Surface tethering of stem cells with H2O2-responsive anti-oxidizing colloidal particles for protection against oxidation-induced death
Q98161425The ACE2-deficient mouse: A model for a cytokine storm-driven inflammation
Q92406209The Ameliorative Effects of the Ethyl Acetate Extract of Salicornia europaea L. and Its Bioactive Candidate, Irilin B, on LPS-Induced Microglial Inflammation and MPTP-Intoxicated PD-Like Mouse Model
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Q64951349The Physiological Functions of Universal Stress Proteins and Their Molecular Mechanism to Protect Plants From Environmental Stresses.
Q92711415The Potential Role of Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) in Glaucoma: A Review
Q90627752The Role of SKQ1 (Visomitin) in Inflammation and Wound Healing of the Ocular Surface
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Q48547168The ultrastructural alterations in the lens capsule and epithelium in eyes with traumatic white cataract.
Q91597541Trends in Research Related to Keratoconus From 2009 to 2018: A Bibliometric and Knowledge Mapping Analysis
Q64859161Understanding multifactorial architecture of Parkinson's disease: pathophysiology to management
Q48127539Unexpected potential protective associations between outdoor air pollution and cataracts
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