| scholarly article | Q13442814 |
| review article | Q7318358 |
| P50 | author | Hongli Wu | Q96169568 |
| Iok-Hou Pang | Q96169572 | ||
| P2093 | author name string | Yang Liu | |
| Christy Xavier | |||
| Shehzad Batliwala | |||
| P2860 | cites work | Chylomicrons promote intestinal absorption and systemic dissemination of dietary antigen (ovalbumin) in mice | Q21090039 |
| NRF2 cysteine residues are critical for oxidant/electrophile-sensing, Kelch-like ECH-associated protein-1-dependent ubiquitination-proteasomal degradation, and transcription activation | Q23923915 | ||
| The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1 | Q24300456 | ||
| A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8 | Q24544001 | ||
| Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain | Q24609907 | ||
| Digenic inheritance of early-onset glaucoma: CYP1B1, a potential modifier gene | Q24633005 | ||
| The Role of the Reactive Oxygen Species and Oxidative Stress in the Pathomechanism of the Age-Related Ocular Diseases and Other Pathologies of the Anterior and Posterior Eye Segments in Adults | Q26765813 | ||
| Barriers to Cataract Surgery in Africa: A Systematic Review | Q26767083 | ||
| Inflammation and its role in age-related macular degeneration | Q26768520 | ||
| Antioxidant responses and cellular adjustments to oxidative stress | Q26800229 | ||
| The proteomics of drusen | Q26997523 | ||
| Redox regulation in the lens | Q28191230 | ||
| The Keap1 BTB/POZ dimerization function is required to sequester Nrf2 in cytoplasm | Q28216217 | ||
| Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis | Q28242612 | ||
| Mechanistic studies of the Nrf2-Keap1 signaling pathway | Q28277182 | ||
| The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity | Q28296400 | ||
| Correlation of nuclear color and opalescence with protein S-thiolation in human lenses | Q28376061 | ||
| Antioxidant-induced modification of INrf2 cysteine 151 and PKC-delta-mediated phosphorylation of Nrf2 serine 40 are both required for stabilization and nuclear translocation of Nrf2 and increased drug resistance | Q28392399 | ||
| Targeting the Nrf2 Signaling Pathway in the Retina With a Gene-Delivered Secretable and Cell-Penetrating Peptide | Q28394174 | ||
| Oxidative lipidomics coming of age: advances in analysis of oxidized phospholipids in physiology and pathology | Q28397441 | ||
| Cytotoxic effects of curcumin in human retinal pigment epithelial cells | Q28488956 | ||
| Epigenetic modification of Sod2 in the development of diabetic retinopathy and in the metabolic memory: role of histone methylation | Q28578457 | ||
| Drusen, choroidal neovascularization, and retinal pigment epithelium dysfunction in SOD1-deficient mice: a model of age-related macular degeneration | Q28590177 | ||
| Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway | Q29547371 | ||
| Hydroperoxide metabolism in mammalian organs | Q29614205 | ||
| Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression | Q29615644 | ||
| Redox proteomics in selected neurodegenerative disorders: from its infancy to future applications. | Q30446460 | ||
| NRF2 plays a protective role in diabetic retinopathy in mice | Q30579323 | ||
| α-Tocopherol is an effective Phase II enzyme inducer: protective effects on acrolein-induced oxidative stress and mitochondrial dysfunction in human retinal pigment epithelial cells | Q39739875 | ||
| Modulation of Nrf2-dependent antioxidant functions in the RPE by Zip2, a zinc transporter protein | Q39995617 | ||
| Heme oxygenase 1 controls early innate immune response of macrophages to Salmonella Typhimurium infection. | Q40004886 | ||
| Association between the 25129A > C polymorphism of the nuclear respiratory factor 2 gene and age-related macular degeneration | Q40139126 | ||
| Self-assembly of protein aggregates in ageing disorders: the lens and cataract model | Q40183669 | ||
| Inter-rater and intra-rater reliability outcomes of a rapid bacteria counting system with pressure ulcer samples. | Q40338780 | ||
| The role of free radicals in disease. | Q40449745 | ||
| Smad3-ATF3 signaling mediates TGF-beta suppression of genes encoding Phase II detoxifying proteins. | Q40475326 | ||
| Molecular mechanism of the regulation of glutathione synthesis by tumor necrosis factor-alpha and dexamethasone in human alveolar epithelial cells | Q40973608 | ||
| Electrical responses from diabetic retina | Q41736666 | ||
| Tobacco smoke: involvement of reactive oxygen species and stable free radicals in mechanisms of oxidative damage, carcinogenesis and synergistic effects with other respirable particles. | Q41832548 | ||
| Curcumin inhibits human retinal pigment epithelial cell proliferation | Q41848097 | ||
| Sulforaphane-induced transcription of thioredoxin reductase in lens: possible significance against cataract formation. | Q42103995 | ||
| Hypoxia-inducible factor 1alpha in the glaucomatous retina and optic nerve head | Q42635765 | ||
| Antioxidants and the integrity of ocular tissues | Q42831147 | ||
| Compositional studies of human RPE lipofuscin | Q42880056 | ||
| Posttranslational modification of cysteine in redox signaling and oxidative stress: Focus on s-glutathionylation | Q43067716 | ||
| Effects of Rosa laevigata Michx. extract on reactive oxygen species production and mitochondrial membrane potential in lens epithelial cells cultured under high glucose | Q43156766 | ||
| Absence of glutaredoxin1 increases lens susceptibility to oxidative stress induced by UVR-B. | Q43296124 | ||
| Abnormalities of retinal metabolism in diabetes and experimental galactosemia. VII. Effect of long-term administration of antioxidants on the development of retinopathy | Q43687875 | ||
| SOD2 knockdown mouse model of early AMD. | Q44260720 | ||
| Oxidative deoxyribonucleic acid damage in the eyes of glaucoma patients | Q44472876 | ||
| Oxidative stress markers in aqueous humor of glaucoma patients | Q44710317 | ||
| Critical role of Nrf2 in oxidative stress-induced retinal ganglion cell death. | Q45391363 | ||
| Keap1/Nrf2 system regulates neuronal survival as revealed through study of keap1 gene-knockout mice | Q46148942 | ||
| Oxidative DNA damage in the human trabecular meshwork: clinical correlation in patients with primary open-angle glaucoma. | Q46433031 | ||
| Feeding preference of Plutella xylostella for leaves treated with plant extracts. | Q46452834 | ||
| May glutathione S-transferase M1 positive genotype afford protection against primary open-angle glaucoma? | Q46466834 | ||
| Escin activates AKT-Nrf2 signaling to protect retinal pigment epithelium cells from oxidative stress | Q46648440 | ||
| Assessment of structure, stability and aggregation of soluble lens proteins and alpha-crystallin upon non-enzymatic glycation: The pathomechanisms underlying cataract development in diabetic patients | Q46652338 | ||
| Salvianolic acid A protects RPE cells against oxidative stress through activation of Nrf2/HO-1 signaling | Q46937795 | ||
| Impact of lifelong exercise training on endothelial ischemia-reperfusion and ischemic preconditioning in humans | Q47944673 | ||
| Protein Corona of Magnetic Hydroxyapatite Scaffold Improves Cell Proliferation via Activation of Mitogen-Activated Protein Kinase Signaling Pathway. | Q48109753 | ||
| Human age‑related cataracts: epigenetic suppression of the nuclear factor erythroid 2‑related factor 2‑mediated antioxidant system | Q85910559 | ||
| Oxidative stress and its downstream signaling in aging eyes. | Q37708674 | ||
| Nrf2 has a protective role against neuronal and capillary degeneration in retinal ischemia-reperfusion injury | Q37719154 | ||
| The importance of mitochondria in age-related and inherited eye disorders. | Q37786972 | ||
| Free radicals, antioxidants and eye diseases: evidence from epidemiological studies on cataract and age-related macular degeneration | Q37786975 | ||
| Oxidation and age-related macular degeneration: insights from molecular biology | Q37801465 | ||
| The Nrf2 system as a potential target for the development of indirect antioxidants. | Q37802176 | ||
| Protective effect of sulforaphane against oxidative stress: recent advances | Q37815695 | ||
| Oxidative stress and Nrf2 in the pathophysiology of diabetic neuropathy: old perspective with a new angle | Q37858072 | ||
| AGEs, RAGE, and diabetic retinopathy | Q37876790 | ||
| Autophagy in the retina: a potential role in age-related macular degeneration | Q37969947 | ||
| Is sunlight exposure a risk factor for age-related macular degeneration? A systematic review and meta-analysis | Q38059178 | ||
| Environmental light and endogenous antioxidants as the main determinants of non-cancer ocular diseases | Q38075688 | ||
| Nrf2 signaling is impaired in the aging RPE given an oxidative insult | Q38161686 | ||
| Apoptosis and oxidative stress in neurodegenerative diseases. | Q38233295 | ||
| S-glutathionylation reactions in mitochondrial function and disease | Q38276703 | ||
| Cell line donor genotype and its influence on experimental phenotype: Toll-like receptor SNPs and potential variability in innate immunity. | Q38379684 | ||
| The role of methylglyoxal and the glyoxalase system in diabetes and other age-related diseases | Q38394355 | ||
| Sulfhydryl-mediated redox signaling in inflammation: role in neurodegenerative diseases | Q38397575 | ||
| Photo-damage, photo-protection and age-related macular degeneration. | Q38551646 | ||
| Lens Development and Crystallin Gene Expression | Q38574366 | ||
| Lens Biology and Biochemistry | Q38574368 | ||
| Introduction to the Retina | Q38574392 | ||
| Tools to fight the cataract epidemic: A review of experimental animal models that mimic age related nuclear cataract | Q38590594 | ||
| The Outflow Pathway: A Tissue With Morphological and Functional Unity. | Q38692787 | ||
| Simultaneous activation of Nrf2 and elevation of antioxidant compounds for reducing oxidative stress and chronic inflammation in human Alzheimer's disease | Q38712027 | ||
| The role of glutathione reductase and related enzymes on cellular redox homoeostasis network. | Q38753585 | ||
| A review of toxicity and mechanisms of individual and mixtures of heavy metals in the environment. | Q38769141 | ||
| Inhibition of DNA methyltransferase or histone deacetylase protects retinal pigment epithelial cells from DNA damage induced by oxidative stress by the stimulation of antioxidant enzymes. | Q38792149 | ||
| Quercetin phospholipid complex significantly protects against oxidative injury in ARPE-19 cells associated with activation of Nrf2 pathway | Q38813929 | ||
| Acetyl-l-carnitine prevents homocysteine-induced suppression of Nrf2/Keap1 mediated antioxidation in human lens epithelial cells | Q38899129 | ||
| Protective effects of resveratrol against UVA-induced damage in ARPE19 cells | Q38899406 | ||
| The mechanism of UVB irradiation induced-apoptosis in cataract | Q38935989 | ||
| Pinosylvin-mediated protection against oxidative stress in human retinal pigment epithelial cells | Q38983537 | ||
| Sulforaphane can protect lens cells against oxidative stress: implications for cataract prevention. | Q39132964 | ||
| A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62. | Q39710585 | ||
| Glutaredoxin 2 knockout increases sensitivity to oxidative stress in mouse lens epithelial cells | Q39723694 | ||
| The Keap1/Nrf2 pathway in health and disease: from the bench to the clinic. | Q53186549 | ||
| Nrf2-encoding NFE2L2 haplotypes influence disease progression but not risk in Alzheimer's disease and age-related cataract. | Q53306943 | ||
| Cytoprotective Effects of a Novel Nrf2 Activator, RS9, in Rhodopsin Pro347Leu Rabbits. | Q53324074 | ||
| Corneal damage and lacrimal gland dysfunction in a smoking rat model. | Q53402212 | ||
| Further observations on the association between smoking and the long-term incidence and progression of age-related macular degeneration: the Beaver Dam Eye Study. | Q53441660 | ||
| Immunostaining of heat shock proteins in the retina and optic nerve head of normal and glaucomatous eyes. | Q53913933 | ||
| Polymorphism of GST and FTO Genes in Risk Prediction of Cataract among a North Indian Population. | Q54212091 | ||
| Glutaredoxin 1 (Grx1) Protects Human Retinal Pigment Epithelial Cells From Oxidative Damage by Preventing AKT Glutathionylation. | Q54283658 | ||
| Antioxidant-induced modification of INrf2 cysteine 151 and PKC-δ-mediated phosphorylation of Nrf2 serine 40 are both required for stabilization and nuclear translocation of Nrf2 and increased drug resistance. | Q55611195 | ||
| Protein profiles in cortical and nuclear regions of aged human donor lenses: A confocal Raman microspectroscopic and imaging study | Q57157031 | ||
| Effect of opacification and pigmentation on human lens protein thiol/disulfide and solubility | Q69748533 | ||
| Further studies on the dynamic changes of glutathione and protein-thiol mixed disulfides in H2O2 induced cataract in rat lenses: distributions and effect of aging | Q70867347 | ||
| Genetic association of manganese superoxide dismutase with exudative age-related macular degeneration | Q73314203 | ||
| Relationship of protein-glutathione mixed disulfide and thioltransferase in H2O2-induced cataract in cultured pig lens | Q73562114 | ||
| Age-related accumulation of free polyunsaturated fatty acids in human retina | Q77745120 | ||
| Antioxidant enzymes in the macular retinal pigment epithelium of eyes with neovascular age-related macular degeneration | Q77893987 | ||
| Does glutathione-S-transferase dethiolate lens protein-thiol mixed disulfides?-A comparative study with thioltransferase | Q77901366 | ||
| Identification of novel mutations causing familial primary congenital glaucoma in Indian pedigrees | Q78020075 | ||
| Thiolation of the gammaB-crystallins in intact bovine lens exposed to hydrogen peroxide | Q78168297 | ||
| Primary congenital glaucoma: a novel single-nucleotide deletion and varying phenotypic expression for the 1,546-1,555dup mutation in the GLC3A (CYP1B1) gene in 2 families of different ethnic origin | Q78884712 | ||
| Protective effect of the thioltransferase gene on in vivo UVR-300 nm-induced cataract | Q82942597 | ||
| Compositional studies of human RPE lipofuscin: mechanisms of molecular modifications | Q83015581 | ||
| Promoter demethylation of Keap1 gene in human diabetic cataractous lenses | Q84343395 | ||
| Autophagy and exosomes in the aged retinal pigment epithelium: possible relevance to drusen formation and age-related macular degeneration | Q30856906 | ||
| Oxidative stress and mitochondrial dysfunction across broad-ranging pathologies: toward mitochondria-targeted clinical strategies | Q33625254 | ||
| Nrf2 amplifies oxidative stress via induction of Klf9. | Q33726837 | ||
| Oxidative damage and age-related macular degeneration | Q33774187 | ||
| Age-related retinopathy in NRF2-deficient mice. | Q33894963 | ||
| Thiol regulation in the lens | Q33913855 | ||
| NSAIDs inhibit neovascularization of choroid through HO-1-dependent pathway | Q33944298 | ||
| Mitochondrial oxidative stress in the retinal pigment epithelium leads to localized retinal degeneration | Q33957336 | ||
| The generation of induced pluripotent stem cells for macular degeneration as a drug screening platform: identification of curcumin as a protective agent for retinal pigment epithelial cells against oxidative stress | Q33984724 | ||
| The role of oxidative stress in the pathogenesis of age-related macular degeneration. | Q34060719 | ||
| Duffy antigen receptor for chemokines mediates chemokine endocytosis through a macropinocytosis-like process in endothelial cells | Q34117806 | ||
| Glutaredoxin 2 prevents H(2)O(2)-induced cell apoptosis by protecting complex I activity in the mitochondria | Q34120771 | ||
| Drusen proteome analysis: an approach to the etiology of age-related macular degeneration. | Q34378842 | ||
| Clinical risk factors for age-related macular degeneration: a systematic review and meta-analysis | Q34437319 | ||
| Molecular basis of the Keap1-Nrf2 system. | Q34482586 | ||
| Epigenetic modifications of Keap1 regulate its interaction with the protective factor Nrf2 in the development of diabetic retinopathy | Q34511162 | ||
| Increased glutathione synthesis through an ARE-Nrf2-dependent pathway by zinc in the RPE: implication for protection against oxidative stress | Q34530340 | ||
| Flavonoids protect human retinal pigment epithelial cells from oxidative-stress-induced death | Q34568613 | ||
| Mitochondrial thioltransferase (glutaredoxin 2) has GSH-dependent and thioredoxin reductase-dependent peroxidase activities in vitro and in lens epithelial cells. | Q34576642 | ||
| Oxidatively modified proteins in aging and disease | Q34615830 | ||
| Epigenetic changes in mitochondrial superoxide dismutase in the retina and the development of diabetic retinopathy | Q34718901 | ||
| Expression and distribution of thiol-regulating enzyme glutaredoxin 2 (GRX2) in porcine ocular tissues. | Q34771614 | ||
| Glutaredoxin 2 (Grx2) gene deletion induces early onset of age-dependent cataracts in mice | Q34774548 | ||
| Lipid peroxidation in aging brain and Alzheimer's disease | Q34809194 | ||
| Heme oxygenase-2 deletion impairs macrophage function: implication in wound healing | Q34847907 | ||
| Valproic acid suppresses Nrf2/Keap1 dependent antioxidant protection through induction of endoplasmic reticulum stress and Keap1 promoter DNA demethylation in human lens epithelial cells | Q34940575 | ||
| Low levels of hydrogen peroxide stimulate corneal epithelial cell adhesion, migration, and wound healing | Q35005956 | ||
| TNFalpha is required for late BRB breakdown in diabetic retinopathy, and its inhibition prevents leukostasis and protects vessels and neurons from apoptosis | Q35005977 | ||
| Loss of thiol repair systems in human cataractous lenses | Q35012811 | ||
| Inhibition of APE1/Ref-1 redox activity rescues human retinal pigment epithelial cells from oxidative stress and reduces choroidal neovascularization | Q35119433 | ||
| Activation of the UPR protects against cigarette smoke-induced RPE apoptosis through up-regulation of Nrf2. | Q35126587 | ||
| Methylglyoxal induces endoplasmic reticulum stress and DNA demethylation in the Keap1 promoter of human lens epithelial cells and age-related cataracts | Q35542218 | ||
| Neuroprotective role of Nrf2 for retinal ganglion cells in ischemia-reperfusion | Q35551091 | ||
| Chromosomal DNA fragmentation in apoptosis and necrosis induced by oxidative stress | Q35557636 | ||
| Investigating mitochondria as a target for treating age-related macular degeneration | Q35572570 | ||
| Association study of detoxification genes in age related macular degeneration | Q35593100 | ||
| Age-related macular degeneration: evaluation and treatment. | Q35611832 | ||
| An association between polymorphism of the heme oxygenase-1 and -2 genes and age-related macular degeneration. | Q35730294 | ||
| The novel triterpenoid RTA 408 protects human retinal pigment epithelial cells against H2O2-induced cell injury via NF-E2-related factor 2 (Nrf2) activation | Q35895835 | ||
| Age-related macular degeneration: anti-vascular endothelial growth factor treatment | Q35933831 | ||
| Glutathione depletion-induced chromosomal DNA fragmentation associated with apoptosis and necrosis. | Q35985532 | ||
| How does the macula protect itself from oxidative stress? | Q36083959 | ||
| Effect of curcumin on aging retinal pigment epithelial cells | Q36111186 | ||
| The retinal pigment epithelium in visual function | Q36178984 | ||
| Oxidative stress response and Nrf2 signaling in aging | Q36236785 | ||
| Ultraviolet radiation-induced cataract in mice: the effect of age and the potential biochemical mechanism. | Q36338106 | ||
| Unfolded protein response is activated in aged retinas | Q36372969 | ||
| Activation of the Nrf2-ARE pathway by siRNA knockdown of Keap1 reduces oxidative stress and provides partial protection from MPTP-mediated neurotoxicity | Q36464631 | ||
| DL-3-n-butylphthalide delays the onset and progression of diabetic cataract by inhibiting oxidative stress in rat diabetic model | Q36497828 | ||
| Oxidative stress in cataracts | Q36502288 | ||
| On the relation of oxidative stress to neuroinflammation: lessons learned from the G93A-SOD1 mouse model of amyotrophic lateral sclerosis | Q36620598 | ||
| Induction of phase 2 genes by sulforaphane protects retinal pigment epithelial cells against photooxidative damage | Q36672378 | ||
| Nrf2--a therapeutic target for the treatment of neurodegenerative diseases | Q36732766 | ||
| Transcription factor Nrf2-mediated antioxidant defense system in the development of diabetic retinopathy | Q36911967 | ||
| Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia | Q36916418 | ||
| Using LC3 to monitor autophagy flux in the retinal pigment epithelium | Q36992034 | ||
| Heme oxygenase-1 deficiency leads to disrupted response to acute stress in stem cells and progenitors | Q37001954 | ||
| Increased Nrf2 activation in livers from Keap1-knockdown mice increases expression of cytoprotective genes that detoxify electrophiles more than those that detoxify reactive oxygen species | Q37101549 | ||
| Epidemiology of diabetes and diabetes-related complications. | Q37273009 | ||
| Essential roles of the PI3 kinase/Akt pathway in regulating Nrf2-dependent antioxidant functions in the RPE. | Q37276044 | ||
| Molecular regulation of cigarette smoke induced-oxidative stress in human retinal pigment epithelial cells: implications for age-related macular degeneration | Q37421027 | ||
| Morphological patterns of lip prints in an Iranian population | Q37491516 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P921 | main subject | transcription factor | Q407384 |
| signal transduction | Q828130 | ||
| oxidative stress | Q898814 | ||
| DNA-binding protein | Q2252764 | ||
| eye disease | Q3041498 | ||
| nuclear factor erythroid 2-related factor 2 | Q24788604 | ||
| physiological phenomenon | Q66615932 | ||
| P5008 | on focus list of Wikimedia project | ScienceSource | Q55439927 |
| P304 | page(s) | 1703810 | |
| P577 | publication date | 2017-03-27 | |
| P1433 | published in | Oxidative medicine and cellular longevity | Q26840015 |
| P1476 | title | Involvement of Nrf2 in Ocular Diseases | |
| P478 | volume | 2017 |
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