Plasmodium falciparum Secretome in Erythrocyte and Beyond

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Plasmodium falciparum Secretome in Erythrocyte and Beyond is …
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P356DOI10.3389/FMICB.2016.00194
P932PMC publication ID4759260
P698PubMed publication ID26925057

P2093author name stringDrista Sharma
Rani Soni
Tarun K Bhatt
P2860cites workThe mature-parasite-infected erythrocyte surface antigen (MESA) of Plasmodium falciparum associates with the erythrocyte membrane skeletal protein, band 4.1.Q68503086
Plasmodium falciparum: protease inhibitors and inhibition of erythrocyte invasionQ68916531
Plasmodium falciparum: the Pf332 antigen is secreted from the parasite by a brefeldin A-dependent pathway and is translocated to the erythrocyte membrane via the Maurer's cleftsQ72798331
Plasmepsin V licenses Plasmodium proteins for export into the host erythrocyteQ24644157
A newly discovered protein export machine in malaria parasitesQ24653443
Ion and nutrient uptake by malaria parasite-infected erythrocytesQ27025767
Merozoite surface protein 1 recognition of host glycophorin A mediates malaria parasite invasion of red blood cellsQ27230075
The malaria secretome: from algorithms to essential function in blood stage infectionQ27318607
Identification of new PNEPs indicates a substantial non-PEXEL exportome and underpins common features in Plasmodium falciparum protein exportQ27334032
Malaria parasite tyrosyl-tRNA synthetase secretion triggers pro-inflammatory responsesQ27675456
A Plasmodium falciparum PHIST protein binds the virulence factor PfEMP1 and comigrates to knobs on the host cell surfaceQ27684513
Structural basis for plasmepsin V inhibition that blocks export of malaria proteins to human erythrocytesQ27701661
Rifins: a second family of clonally variant proteins expressed on the surface of red cells infected with Plasmodium falciparumQ27972160
Knob proteins in falciparum malariaQ27972543
STEVOR is a Plasmodium falciparum erythrocyte binding protein that mediates merozoite invasion and rosettingQ27972547
PTEX component HSP101 mediates export of diverse malaria effectors into host erythrocytesQ27972589
Processing of Plasmodium falciparum Merozoite Surface Protein MSP1 Activates a Spectrin-Binding Function Enabling Parasite Egress from RBCsQ27972787
Subcellular localization of adenylate kinases in Plasmodium falciparumQ27972936
Functional alteration of red blood cells by a megadalton protein of Plasmodium falciparumQ27973442
Alternative Protein Secretion in the Malaria Parasite Plasmodium falciparumQ27973664
A cluster of ring stage-specific genes linked to a locus implicated in cytoadherence in Plasmodium falciparum codes for PEXEL-negative and PEXEL-positive proteins exported into the host cellQ27974142
Na(+) regulation in the malaria parasite Plasmodium falciparum involves the cation ATPase PfATP4 and is a target of the spiroindolone antimalarialsQ27976482
N-terminal processing of proteins exported by malaria parasitesQ28282814
Interaction of Plasmodium falciparum knob-associated histidine-rich protein (KAHRP) with erythrocyte ankyrin R is required for its attachment to the erythrocyte membraneQ28299744
Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasitesQ28540204
The pathogenic basis of malariaQ29615020
A proteomic view of the Plasmodium falciparum life cycleQ29618807
A host-targeting signal in virulence proteins reveals a secretome in malarial infectionQ29619928
Targeting malaria virulence and remodeling proteins to the host erythrocyteQ29620631
Skeleton-binding protein 1 functions at the parasitophorous vacuole membrane to traffic PfEMP1 to the Plasmodium falciparum-infected erythrocyte surfaceQ30038747
Maurer's clefts: a novel multi-functional organelle in the cytoplasm of Plasmodium falciparum-infected erythrocytesQ30039037
The role of palmitoylation for protein recruitment to the inner membrane complex of the malaria parasiteQ30039084
Perforin-like protein PPLP2 permeabilizes the red blood cell membrane during egress of Plasmodium falciparum gametocytesQ30041353
PTEX is an essential nexus for protein export in malaria parasitesQ30042849
A member of the Plasmodium falciparum PHIST family binds to the erythrocyte cytoskeleton component band 4.1Q30043144
Structural and functional studies of interaction between Plasmodium falciparum knob-associated histidine-rich protein (KAHRP) and erythrocyte spectrinQ30046785
A brief illustrated guide to the ultrastructure of Plasmodium falciparum asexual blood stagesQ30929856
Identification of proteins secreted by malaria parasite into erythrocyte using SVM and PSSM profilesQ33328691
Prediction of extracellular proteases of the human pathogen Helicobacter pylori reveals proteolytic activity of the Hp1018/19 protein HtrAQ33378901
Secretome: clues into pathogen infection and clinical applicationsQ33600144
An aspartyl protease directs malaria effector proteins to the host cellQ33639304
Molecular mechanisms of cytoadherence in malaria.Q33654265
Cytoadherence, pathogenesis and the infected red cell surface in Plasmodium falciparum.Q33730132
Adhesion of Plasmodium falciparum-infected erythrocytes to human cells: molecular mechanisms and therapeutic implications.Q33884983
Immune mimicry in malaria: Plasmodium falciparum secretes a functional histamine-releasing factor homolog in vitro and in vivoQ33943881
Investigating the function of Fc-specific binding of IgM to Plasmodium falciparum erythrocyte membrane protein 1 mediating erythrocyte rosettingQ39490520
PfEMP1 expression is reduced on the surface of knobless Plasmodium falciparum infected erythrocytesQ39718337
Plasmodium falciparum rosetting is associated with malaria severity in KenyaQ39822248
Malaria pathogenesisQ40659853
Endoplasmic reticulum PI(3)P lipid binding targets malaria proteins to the host cellQ40741294
The proteases and pathogenicity of parasitic protozoaQ40788600
Membrane modifications in erythrocytes parasitized by Plasmodium falciparumQ41214287
Plasmodium falciparum-infected erythrocytes form spontaneous erythrocyte rosettesQ42573749
Characterization of N-myristoyltransferase from Plasmodium falciparumQ42626598
stevor and rif are Plasmodium falciparum multicopy gene families which potentially encode variant antigensQ42689345
Recombinant falcipain-2 cleaves erythrocyte membrane ankyrin and protein 4.1.Q43681696
A malaria scavenger receptor-like protein essential for parasite development.Q44149219
Infection of human macrophages and dendritic cells with Mycobacterium tuberculosis induces a differential cytokine gene expression that modulates T cell responseQ44178645
Morphology and kinetics of the three distinct phases of red blood cell invasion by Plasmodium falciparum merozoitesQ44299001
Mapping the binding domains involved in the interaction between the Plasmodium falciparum knob-associated histidine-rich protein (KAHRP) and the cytoadherence ligand P. falciparum erythrocyte membrane protein 1 (PfEMP1).Q47851406
Arresting malaria parasite egress from infected red blood cells.Q47860541
A cysteine protease activity from Plasmodium falciparum cleaves human erythrocyte ankyrinQ47873809
Short report: Positive correlation between rosetting and parasitemia in Plasmodium falciparum clinical isolates.Q47911242
Membrane transport proteins of the malaria parasiteQ47915147
Generation of an erythrocyte vesicle transport system by Plasmodium falciparum malaria parasitesQ47932506
Malaria and the permeability of the host erythrocyteQ47945242
Moving in and renovating: exporting proteins from Plasmodium into host erythrocytesQ47950208
The fine structure of trophozoites and gametocytes in Plasmodium coatneyiQ47954146
Plasmodium falciparum induces reorganization of host membrane proteins during intraerythrocytic growthQ47970169
Permselectivity changes in malaria (Plasmodium falciparum) infected human red blood cell membranesQ47975922
New permeability pathways induced in membranes of Plasmodium falciparum infected erythrocytesQ47976906
Plasmodium knowlesi: studies on invasion of rhesus erythrocytes by merozoites in the presence of protease inhibitorsQ47988661
Clinical disease and pathogenesis in malariaQ47990034
Protein unfolding is an essential requirement for transport across the parasitophorous vacuolar membrane of Plasmodium falciparumQ50116191
Both LCCL-domains of human CRISPLD2 have high affinity for lipid A.Q50718172
Trafficking determinants for PfEMP3 export and assembly under the Plasmodium falciparum-infected red blood cell membrane.Q50748873
Deciphering the export pathway of malaria surface proteinsQ36537326
Changes in the plasmodial surface anion channel reduce leupeptin uptake and can confer drug resistance in Plasmodium falciparum-infected erythrocytes.Q36744868
The fine structure of Plasmodium falciparum and its host erythrocytes in natural malarial infections in man.Q36779334
Erythrocyte remodeling by malaria parasitesQ36783455
Protein transport across the parasitophorous vacuole of Plasmodium falciparum: into the great wide openQ36974914
Protein export in malaria parasites: many membranes to crossQ37126101
Helminth immunoregulation: the role of parasite secreted proteins in modulating host immunity.Q37253393
Parasite antigens on the infected red cell surface are targets for naturally acquired immunity to malaria.Q37331646
Proteome analysis of Plasmodium falciparum extracellular secretory antigens at asexual blood stages reveals a cohort of proteins with possible roles in immune modulation and signalingQ37343084
Malaria parasite proteins that remodel the host erythrocyteQ37445490
The Plasmodium falciparum translationally controlled tumor protein (TCTP) is incorporated more efficiently into B cells than its human homologueQ37490702
Protein export in malaria parasites: do multiple export motifs add up to multiple export pathways?Q37625114
Variant antigens and endothelial receptor adhesion in Plasmodium falciparumQ37659498
Vesicle-mediated transport of membrane and proteins in malaria-infected erythrocytesQ38008940
Identification of Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) as the rosetting ligand of the malaria parasite P. falciparumQ38340612
Ion Regulation in the Malaria ParasiteQ38612987
Host ICAMs play a role in cell invasion by Mycobacterium tuberculosis and Plasmodium falciparumQ38920235
Transition state mimetics of the Plasmodium export element are potent inhibitors of Plasmepsin V from P. falciparum and P. vivaxQ38962132
Uncovering common principles in protein export of malaria parasitesQ39034758
The Maurer's cleft protein MAHRP1 is essential for trafficking of PfEMP1 to the surface of Plasmodium falciparum-infected erythrocytesQ39483851
The Caenorhabditis elegans sel-1 gene, a negative regulator of lin-12 and glp-1, encodes a predicted extracellular protein.Q33967319
Trafficking and assembly of the cytoadherence complex in Plasmodium falciparum-infected human erythrocytesQ34082841
Platelet-mediated clumping of Plasmodium falciparum-infected erythrocytes is a common adhesive phenotype and is associated with severe malariaQ34105789
Malaria: Protein-export pathway illuminatedQ34118939
A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cellsQ34276770
Maurer's clefts, the enigma of Plasmodium falciparumQ34388395
Targeted gene disruption shows that knobs enable malaria-infected red cells to cytoadhere under physiological shear stress.Q34422119
The malaria-infected red blood cell: structural and functional changesQ34470655
The role of KAHRP domains in knob formation and cytoadherence of P falciparum-infected human erythrocytesQ34498333
How protozoan parasites evade the immune responseQ34661000
Protein and lipid trafficking induced in erythrocytes infected by malaria parasitesQ34725818
Band 3 is a host receptor binding merozoite surface protein 1 during thePlasmodium falciparuminvasion of erythrocytesQ34982236
Evasion of innate immunity by parasitic protozoaQ34983845
Malaria parasite clag3 genes determine channel-mediated nutrient uptake by infected red blood cellsQ35017627
Suppression of adaptive immunity to heterologous antigens during Plasmodium infection through hemozoin-induced failure of dendritic cell functionQ35019935
Identification of important interacting proteins (IIPs) in Plasmodium falciparum using large-scale interaction network analysis and in-silico knock-out studiesQ35097316
Impairment of T cell function in parasitic infectionsQ35097790
Maurer's clefts--a novel secretory organelle?Q35561783
A CLAG3 mutation in an amphipathic transmembrane domain alters malaria parasite nutrient channels and confers leupeptin resistanceQ35609409
Multiple stiffening effects of nanoscale knobs on human red blood cells infected with Plasmodium falciparum malaria parasiteQ35616004
Effect of plasmodial RESA protein on deformability of human red blood cells harboring Plasmodium falciparum.Q35803544
α2-Macroglobulin Can Crosslink Multiple Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) Molecules and May Facilitate Adhesion of Parasitized ErythrocytesQ35811289
Dendritic cells, pro-inflammatory responses, and antigen presentation in a rodent malaria infectionQ35884189
Plasmodium falciparum Infection of Human Volunteers Activates Monocytes and CD16+ Dendritic Cells and Induces Upregulation of CD16 and CD1c ExpressionQ35947450
Malaria: immune evasion by parasitesQ36032308
Multiple Plasmodium falciparum Erythrocyte Membrane Protein 1 Variants per Genome Can Bind IgM via Its Fc Fragment FcμQ36053493
TLRs innate immunereceptors and Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) CIDR1α-driven human polyclonal B-cell activationQ36121797
Targets of antibodies against Plasmodium falciparum-infected erythrocytes in malaria immunityQ36190707
Malaria infection changes the ability of splenic dendritic cell populations to stimulate antigen-specific T cellsQ36228661
Signal-mediated export of proteins from the malaria parasite to the host erythrocyte.Q36318864
Cytoadherence by Plasmodium falciparum-infected erythrocytes is correlated with the expression of a family of variable proteins on infected erythrocytesQ36355465
LCCL proteins of apicomplexan parasites.Q36398137
Solute restriction reveals an essential role for clag3-associated channels in malaria parasite nutrient acquisitionQ36412823
The long and winding road: protein trafficking mechanisms in the Plasmodium falciparum infected erythrocyteQ36422380
P407language of work or nameEnglishQ1860
P921main subjectPlasmodium falciparumQ311383
secretomeQ17042943
P304page(s)194
P577publication date2016-01-01
P1433published inFrontiers in MicrobiologyQ27723481
P1476titlePlasmodium falciparum Secretome in Erythrocyte and Beyond
P478volume7

Reverse relations

Q48021242Correlation of APRIL with production of inflammatory cytokines during acute malaria in the Brazilian Amazon.cites workP2860

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