T Cells and Cancer: How Metabolism Shapes Immunity

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T Cells and Cancer: How Metabolism Shapes Immunity is …
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scholarly articleQ13442814

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P356DOI10.3389/FIMMU.2016.00020
P3181OpenCitations bibliographic resource ID1332881
P932PMC publication ID4740780
P698PubMed publication ID26870036
P5875ResearchGate publication ID292589675

P50authorAntonella ViolaQ50923744
Bianca CalìQ60984758
P2093author name stringBarbara Molon
P2860cites workHallmarks of Cancer: The Next GenerationQ22252312
Posttranscriptional control of T cell effector function by aerobic glycolysisQ24606942
Safety, activity, and immune correlates of anti-PD-1 antibody in cancerQ24633070
mTOR signaling in growth control and diseaseQ24634174
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3Q24672849
Trial watch: IDO inhibitors in cancer therapyQ27006866
Glutamine and cancer: cell biology, physiology, and clinical opportunitiesQ27011818
Spotlights on immunological effects of reactive nitrogen species: When inflammation says nitric oxideQ27694770
Targeting HIF-1 for cancer therapyQ27860504
Improved Survival with Ipilimumab in Patients with Metastatic MelanomaQ27861062
Metabolic Reprogramming of Immune Cells in Cancer ProgressionQ28081682
Type, density, and location of immune cells within human colorectal tumors predict clinical outcomeQ28131662
Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenaseQ28204166
Progress and promise of FDG-PET imaging for cancer patient management and oncologic drug developmentQ28245741
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survivalQ29547865
Regulation of immune responses by L-arginine metabolismQ29614284
Autophagy and metabolismQ29615974
The LKB1-AMPK pathway: metabolism and growth control in tumour suppressionQ29617506
AMP-activated protein kinase induces a p53-dependent metabolic checkpointQ29618123
The impact of O2 availability on human cancerQ29619884
Tumor metabolism as modulator of immune response and tumor progressionQ33353192
Complement Regulates Nutrient Influx and Metabolic Reprogramming during Th1 Cell ResponsesQ33423703
Signaling defects in T lymphocytes of patients with malignancyQ33740933
Higher FOXP3-TSDR demethylation rates in adjacent normal tissues in patients with colon cancer were associated with worse survival.Q33818673
The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector functionQ33838591
Anergic T cells are metabolically anergicQ33908515
Proteomic method identifies proteins nitrated in vivo during inflammatory challengeQ33947294
Cancer-induced defective cytotoxic T lymphocyte effector function: another mechanism how antigenic tumors escape immune-mediated killingQ34022805
The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activationQ34242691
Indoleamine 2,3 dioxygenase and metabolic control of immune responsesQ34308495
Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: in vivo persistence, migration, and antitumor effect of transferred T cellsQ34415738
mTOR- and HIF-1α-mediated aerobic glycolysis as metabolic basis for trained immunity.Q34481477
The CD28 signaling pathway regulates glucose metabolismQ34525357
Tryptophan-degrading enzymes in tumoral immune resistanceQ35042385
Melanoma-initiating cells exploit M2 macrophage TGFβ and arginase pathway for survival and proliferation.Q35067933
HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cellsQ35102340
Hypoxia-inducible factors as essential regulators of inflammationQ35130618
Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells.Q35237477
PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidationQ35311785
T cell metabolic fitness in antitumor immunityQ35371293
Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.Q35404457
Aryl hydrocarbon receptor ligands in cancer: friend and foe.Q35458027
Arginases I and II: do their functions overlap?Q35722017
Cytokine stimulation promotes glucose uptake via phosphatidylinositol-3 kinase/Akt regulation of Glut1 activity and traffickingQ35723690
Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.Q36054460
Altered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancerQ36260673
Boosting antitumor responses of T lymphocytes infiltrating human prostate cancers.Q36403503
Nitric oxide, a double edged sword in cancer biology: searching for therapeutic opportunitiesQ36601025
Metabolic regulation of T lymphocytesQ36711431
Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survivalQ37199519
Inhibitors of indoleamine-2,3-dioxygenase for cancer therapy: can we see the wood for the trees?Q37492248
Prognostic significance of regulatory T cells in tumorQ37754132
Indoleamine 2,3-dioxygenase expression in human cancers: clinical and immunologic perspectivesQ37954141
Lactate: a metabolic key player in cancerQ37956296
From tumor cell metabolism to tumor immune escapeQ38008488
Tryptophan catabolism in cancer: beyond IDO and tryptophan depletionQ38054472
Metabolism of stromal and immune cells in health and diseaseQ38227775
Deficiency of AMPK in CD8+ T cells suppresses their anti-tumor function by inducing protein phosphatase-mediated cell deathQ38901228
A mechanism of hypoxia-mediated escape from adaptive immunity in cancer cellsQ39043650
Glycolytic metabolism and tumour response to fractionated irradiation.Q39758697
Tumor-secreted lactic acid promotes IL-23/IL-17 proinflammatory pathwayQ39980595
Expression of indoleamine 2,3-dioxygenase in tumor endothelial cells correlates with long-term survival of patients with renal cell carcinomaQ40041177
Decreased serum tryptophan concentration predicts poor prognosis in malignant melanoma patientsQ40257073
The energy sensor AMPK regulates T cell metabolic adaptation and effector responses in vivoQ41530637
Glutaminolysis: Supplying carbon or nitrogen or both for cancer cells?Q42858457
Regulatory (FoxP3+) T-cell tumor infiltration is a favorable prognostic factor in advanced colon cancer patients undergoing chemo or chemoimmunotherapyQ43102151
Selective inhibition of IDO1 effectively regulates mediators of antitumor immunityQ43144666
The mTOR kinase determines effector versus memory CD8+ T cell fate by regulating the expression of transcription factors T-bet and EomesoderminQ43199035
Arginase I production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigen-specific T-cell responsesQ45020410
Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional toleranceQ47755230
Hypoxia and acidosis independently up-regulate vascular endothelial growth factor transcription in brain tumors in vivo.Q55474168
Tumor-Infiltrating FOXP3+ T Regulatory Cells Show Strong Prognostic Significance in Colorectal CancerQ57254166
High lactate levels predict likelihood of metastases, tumor recurrence, and restricted patient survival in human cervical cancersQ73519226
Peroxynitrite inhibits T lymphocyte activation and proliferation by promoting impairment of tyrosine phosphorylation and peroxynitrite-driven apoptotic deathQ74638430
THE VASCULAR SPACE OF GROWING TUMORSQ77070747
Inhibitory effect of tumor cell-derived lactic acid on human T cellsQ79666516
Modulation of human T-cell functions by reactive nitrogen speciesQ83823148
High frequency of tumor-infiltrating FOXP3(+) regulatory T cells predicts improved survival in mismatch repair-proficient colorectal cancer patientsQ84782027
P407language of work or nameEnglishQ1860
P304page(s)20
P577publication date2016-01-01
P1433published inFrontiers in ImmunologyQ27723748
P1476titleT Cells and Cancer: How Metabolism Shapes Immunity
P478volume7