| scholarly article | Q13442814 |
| P2093 | author name string | Xu Y | |
| Birnbaum MJ | |||
| Buzzai M | |||
| Jones RG | |||
| Kubek S | |||
| Mu J | |||
| Plas DR | |||
| Thompson CB | |||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 283-93 | |
| P577 | publication date | 2005-04-29 | |
| P1433 | published in | Molecular Cell | Q3319468 |
| P1476 | title | AMP-activated protein kinase induces a p53-dependent metabolic checkpoint | |
| P478 | volume | 18 |
| Q33747374 | 2-Deoxy-d-Glucose Treatment Decreases Anti-inflammatory M2 Macrophage Polarization in Mice with Tumor and Allergic Airway Inflammation |
| Q35950107 | 5-Aminoimidazole-4-carboxyamide ribonucleoside induces G(1)/S arrest and Nanog downregulation via p53 and enhances erythroid differentiation |
| Q39251904 | 5-Fluorouracil signaling through a calcium-calmodulin-dependent pathway is required for p53 activation and apoptosis in colon carcinoma cells |
| Q89514232 | 6'-O-galloylpaeoniflorin regulates proliferation and metastasis of non-small cell lung cancer through AMPK/miR-299-5p/ATF2 axis |
| Q60957590 | A Contraction Stress Model of Hypertrophic Cardiomyopathy due to Sarcomere Mutations |
| Q51760784 | A RAS-CaMKKβ-AMPKα2 pathway promotes senescence by licensing post-translational activation of C/EBPβ through a novel 3'UTR mechanism. |
| Q38758189 | A Systems Survey of Progressive Host-Cell Reorganization during Rotavirus Infection |
| Q37249372 | A complex barcode underlies the heterogeneous response of p53 to stress |
| Q27659450 | A conserved mechanism of autoinhibition for the AMPK kinase domain: ATP-binding site and catalytic loop refolding as a means of regulation |
| Q35285480 | A divergent role of the SIRT1-TopBP1 axis in regulating metabolic checkpoint and DNA damage checkpoint. |
| Q52576454 | A germ line mutation in the death domain of DAPK-1 inactivates ERK-induced apoptosis. |
| Q30488844 | A hyperfused mitochondrial state achieved at G1-S regulates cyclin E buildup and entry into S phase |
| Q34035645 | A low-carb diet kills tumor cells with a mutant p53 tumor suppressor gene: the Atkins diet suppresses tumor growth |
| Q41352841 | A metabolic stress-induced cell cycle checkpoint in stem cells |
| Q24293006 | A new role of NUAK1: directly phosphorylating p53 and regulating cell proliferation |
| Q36114705 | A novel inverse relationship between metformin-triggered AMPK-SIRT1 signaling and p53 protein abundance in high glucose-exposed HepG2 cells |
| Q28389607 | A novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuroprogenitor and murine striatal models of Huntington's disease |
| Q37014884 | A novel mechanism by which SDF-1β protects cardiac cells from palmitate-induced endoplasmic reticulum stress and apoptosis via CXCR7 and AMPK/p38 MAPK-mediated interleukin-6 generation |
| Q39881896 | A nucleocytoplasmic malate dehydrogenase regulates p53 transcriptional activity in response to metabolic stress |
| Q36841610 | A pivotal role for p53: balancing aerobic respiration and glycolysis |
| Q47240106 | A reappraisal on metformin |
| Q51686167 | A short acidic motif in ARF guards against mitochondrial dysfunction and melanoma susceptibility. |
| Q36037994 | A small molecule Inauhzin inhibits SIRT1 activity and suppresses tumour growth through activation of p53. |
| Q39124486 | A spatiotemporal hypothesis for the regulation, role, and targeting of AMPK in prostate cancer. |
| Q47235068 | A systematic review of p53 regulation of oxidative stress in skeletal muscle. |
| Q46377922 | AICAR induces Bax/Bak-dependent apoptosis through upregulation of the BH3-only proteins Bim and Noxa in mouse embryonic fibroblasts |
| Q89551502 | AMP-Activated Protein Kinase (AMPK) at the Crossroads Between CO2 Retention and Skeletal Muscle Dysfunction in Chronic Obstructive Pulmonary Disease (COPD) |
| Q35641071 | AMP-Activated Protein Kinase Regulates the Cell Surface Proteome and Integrin Membrane Traffic |
| Q22241925 | AMP-Activated Protein Kinase in Metabolic Control and Insulin Signaling |
| Q37094565 | AMP-Activated Protein Kinase α 2 Isoform Suppression in Primary Breast Cancer Alters AMPK Growth Control and Apoptotic Signaling |
| Q36282831 | AMP-activated Protein Kinase (AMPK) Control of mTORC1 Is p53- and TSC2-independent in Pemetrexed-treated Carcinoma Cells |
| Q36776165 | AMP-activated protein kinase (AMPK) activation regulates in vitro bone formation and bone mass |
| Q38150151 | AMP-activated protein kinase (AMPK) beyond metabolism: a novel genomic stress sensor participating in the DNA damage response pathway |
| Q34333672 | AMP-activated protein kinase (AMPK) negatively regulates Nox4-dependent activation of p53 and epithelial cell apoptosis in diabetes. |
| Q46250581 | AMP-activated protein kinase (AMPK)/Ulk1-dependent autophagic pathway contributes to C6 ceramide-induced cytotoxic effects in cultured colorectal cancer HT-29 cells |
| Q37394486 | AMP-activated protein kinase adapts rRNA synthesis to cellular energy supply |
| Q37685196 | AMP-activated protein kinase and energy balance in breast cancer |
| Q36756228 | AMP-activated protein kinase and its downstream transcriptional pathways |
| Q33825016 | AMP-activated protein kinase antagonizes pro-apoptotic extracellular signal-regulated kinase activation by inducing dual-specificity protein phosphatases in response to glucose deprivation in HCT116 carcinoma |
| Q39948889 | AMP-activated protein kinase contributes to UV- and H2O2-induced apoptosis in human skin keratinocytes |
| Q37546075 | AMP-activated protein kinase induces p53 by phosphorylating MDMX and inhibiting its activity |
| Q41005568 | AMP-activated protein kinase inhibits Kv 1.5 channel currents of pulmonary arterial myocytes in response to hypoxia and inhibition of mitochondrial oxidative phosphorylation. |
| Q37856788 | AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan |
| Q53500309 | AMP-activated protein kinase inhibits transforming growth factor-beta-induced Smad3-dependent transcription and myofibroblast transdifferentiation. |
| Q37143228 | AMP-activated protein kinase phosphorylates retinoblastoma protein to control mammalian brain development |
| Q89295005 | AMP-activated protein kinase promotes epithelial-mesenchymal transition in cancer cells through Twist1 upregulation |
| Q37415957 | AMP-activated protein kinase promotes human prostate cancer cell growth and survival |
| Q39645465 | AMP-activated protein kinase regulates glucagon secretion from mouse pancreatic alpha cells. |
| Q59811660 | AMP-activated protein kinase regulates the expression of human telomerase reverse transcriptase |
| Q31158130 | AMP-activated protein kinase suppresses the in vitro and in vivo proliferation of hepatocellular carcinoma |
| Q37596326 | AMP-activated protein kinase α2 and E2F1 transcription factor mediate doxorubicin-induced cytotoxicity by forming a positive signal loop in mouse embryonic fibroblasts and non-carcinoma cells |
| Q24610297 | AMP-activated protein kinase, stress responses and cardiovascular diseases |
| Q36462587 | AMP-activated protein kinase--development of the energy sensor concept. |
| Q28074581 | AMP-activated protein kinase: a cellular energy sensor that comes in 12 flavours |
| Q26864424 | AMP-activated protein kinase: a target for drugs both ancient and modern |
| Q26865723 | AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function |
| Q38019034 | AMP-activated protein kinase: new regulation, new roles? |
| Q92342120 | AMP-activated protein kinase: the current landscape for drug development |
| Q29618101 | AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy |
| Q42291697 | AMPK Causes Cell Cycle Arrest in LKB1-Deficient Cells via Activation of CAMKK2 |
| Q36174103 | AMPK Promotes Aberrant PGC1β Expression To Support Human Colon Tumor Cell Survival |
| Q38998395 | AMPK Regulation of Cell Growth, Apoptosis, Autophagy, and Bioenergetics. |
| Q36906672 | AMPK Signaling in the Dorsal Hippocampus Negatively Regulates Contextual Fear Memory Formation |
| Q35986123 | AMPK activation by dihydrotestosterone reduces FSH-stimulated cell proliferation in rat granulosa cells by inhibiting ERK signaling pathway |
| Q64898547 | AMPK activation induced in pemetrexed-treated cells is associated with development of drug resistance independently of target enzyme expression. |
| Q30651985 | AMPK activation promotes lipid droplet dispersion on detyrosinated microtubules to increase mitochondrial fatty acid oxidation. |
| Q33689169 | AMPK activation--protean potential for boosting healthspan |
| Q26749158 | AMPK activators: mechanisms of action and physiological activities |
| Q38998413 | AMPK and Cancer |
| Q38853225 | AMPK and HIF signaling pathways regulate both longevity and cancer growth: the good news and the bad news about survival mechanisms |
| Q38792676 | AMPK and PKA interaction in the regulation of survival of liver cancer cells subjected to glucose starvation. |
| Q36448932 | AMPK and cell proliferation--AMPK as a therapeutic target for atherosclerosis and cancer |
| Q33789079 | AMPK as a metabolic tumor suppressor: control of metabolism and cell growth |
| Q26829427 | AMPK as a potential anticancer target - friend or foe? |
| Q42787867 | AMPK couples p73 with p53 in cell fate decision. |
| Q34235694 | AMPK directly inhibits NDPK through a phosphoserine switch to maintain cellular homeostasis. |
| Q38264144 | AMPK in lymphocyte metabolism and function |
| Q24629417 | AMPK in the brain: its roles in energy balance and neuroprotection |
| Q35094436 | AMPK inhibition in health and disease |
| Q44948044 | AMPK inhibits myoblast differentiation through a PGC-1alpha-dependent mechanism. |
| Q36532941 | AMPK is a negative regulator of the Warburg effect and suppresses tumor growth in vivo |
| Q42367828 | AMPK maintains energy homeostasis and survival in cancer cells via regulating p38/PGC-1α-mediated mitochondrial biogenesis |
| Q50290367 | AMPK phosphorylates TP53 |
| Q24329244 | AMPK phosphorylation of raptor mediates a metabolic checkpoint |
| Q36207311 | AMPK promotes p53 acetylation via phosphorylation and inactivation of SIRT1 in liver cancer cells. |
| Q36713683 | AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress |
| Q33683315 | AMPK signaling in the nucleus accumbens core mediates cue-induced reinstatement of cocaine seeking |
| Q38764024 | AMPK β1 reduces tumor progression and improves survival in p53 null mice. |
| Q36920118 | AMPK-dependent phosphorylation of ULK1 regulates ATG9 localization |
| Q92284495 | AMPK-mediated activation of MCU stimulates mitochondrial Ca2+ entry to promote mitotic progression |
| Q57810311 | AMPK: An Epigenetic Landscape Modulator |
| Q37153612 | AMPK: Lessons from transgenic and knockout animals |
| Q60927924 | AMPK: Regulation of Metabolic Dynamics in the Context of Autophagy |
| Q26995682 | AMPK: a cellular metabolic and redox sensor. A minireview |
| Q38104227 | AMPK: a contextual oncogene or tumor suppressor? |
| Q29615410 | AMPK: a nutrient and energy sensor that maintains energy homeostasis |
| Q27002908 | AMPK: a target for drugs and natural products with effects on both diabetes and cancer |
| Q45982416 | AMPK: guardian of metabolism and mitochondrial homeostasis. |
| Q37414462 | AMPKα modulation in cancer progression: multilayer integrative analysis of the whole transcriptome in Asian gastric cancer |
| Q33761719 | AMPKα phosphatase Ppm1E upregulation in human gastric cancer is required for cell proliferation |
| Q34614152 | AMPKα1 deficiency promotes cellular proliferation and DNA damage via p21 reduction in mouse embryonic fibroblasts |
| Q42269205 | AMPKα2 Suppresses Murine Embryonic Fibroblast Transformation and Tumorigenesis |
| Q36465010 | ATM and LKB1 dependent activation of AMPK sensitizes cancer cells to etoposide-induced apoptosis |
| Q53228637 | ATP-citrate lyase regulates cellular senescence via an AMPK- and p53-dependent pathway. |
| Q30618321 | Ablation of AMP-activated protein kinase alpha1 and alpha2 from mouse pancreatic beta cells and RIP2.Cre neurons suppresses insulin release in vivo |
| Q35861043 | Abrogation of de novo lipogenesis by stearoyl-CoA desaturase 1 inhibition interferes with oncogenic signaling and blocks prostate cancer progression in mice |
| Q28243076 | Accelerated cellular senescence phenotype of GAPDH-depleted human lung carcinoma cells |
| Q43077970 | Acetic acid effects on aging in budding yeast: are they relevant to aging in higher eukaryotes? |
| Q27930160 | Acetylation of yeast AMPK controls intrinsic aging independently of caloric restriction |
| Q39297835 | Activation of AMP-activated Protein Kinase by Metformin Induces Protein Acetylation in Prostate and Ovarian Cancer Cells |
| Q34412530 | Activation of AMP-activated Protein Kinase by Temozolomide Contributes to Apoptosis in Glioblastoma Cells via p53 Activation and mTORC1 Inhibition |
| Q41811796 | Activation of AMP-activated protein kinase in cerebella of Atm-/- mice is attributable to accumulation of reactive oxygen species |
| Q46868426 | Activation of AMP-activated protein kinase induces p53-dependent apoptotic cell death in response to energetic stress |
| Q36174159 | Activation of AMP-activated protein kinase inhibits the proliferation of human endothelial cells |
| Q33533561 | Activation of AMP-activated protein kinase stimulates the nuclear localization of glyceraldehyde 3-phosphate dehydrogenase in human diploid fibroblasts |
| Q37454154 | Activation of AMP-activated protein kinase suppresses oxidized low-density lipoprotein-induced macrophage proliferation |
| Q40452377 | Activation of p53/miR-34a Tumor Suppressor Axis by Chinese Herbal Formula JP-1 in A549 Lung Adenocarcinoma Cells. |
| Q28729157 | Activation of β-catenin by oncogenic PIK3CA and EGFR promotes resistance to glucose deprivation by inducing a strong antioxidant response |
| Q28482314 | Acute activation of AMP-activated protein kinase prevents H2O2-induced premature senescence in primary human keratinocytes |
| Q45837026 | Acute exercise induces tumour suppressor protein p53 translocation to the mitochondria and promotes a p53-Tfam-mitochondrial DNA complex in skeletal muscle |
| Q33911700 | Adaptation to HIF-1 deficiency by upregulation of the AMP/ATP ratio and phosphofructokinase activation in hepatomas |
| Q42541256 | Adaptation to metabolic stress: insights into a paradoxical Q. |
| Q39881905 | Adaptive response to l-serine deficiency is mediated by p38 MAPK activation via 1-deoxysphinganine in normal fibroblasts |
| Q37429979 | Additive interactions between PRKAA1 polymorphisms and Helicobacter pylori CagA infection associated with gastric cancer risk in Koreans |
| Q46837274 | Adenosine monophosphate-activated protein kinase modulates the activated phenotype of hepatic stellate cells. |
| Q36316592 | Advances in gas chromatographic methods for the identification of biomarkers in cancer. |
| Q42409336 | Aerobic Glycolysis Suppresses p53 Activity to Provide Selective Protection from Apoptosis upon Loss of Growth Signals or Inhibition of BCR-Abl |
| Q34568683 | Akt requires glucose metabolism to suppress puma expression and prevent apoptosis of leukemic T cells |
| Q37114404 | Akt-dependent and -independent mechanisms of mTOR regulation in cancer |
| Q36313173 | Akt-dependent transformation: there is more to growth than just surviving |
| Q37339508 | Altered metabolism in head and neck squamous cell carcinoma: an opportunity for identification of novel biomarkers and drug targets |
| Q27009377 | Amino acids and mTORC1: from lysosomes to disease |
| Q35091072 | Ammonia-induced autophagy is independent of ULK1/ULK2 kinases |
| Q40029015 | An E2F1-dependent gene expression program that determines the balance between proliferation and cell death |
| Q35195372 | Analysis of p53 transactivation domain mutants reveals Acad11 as a metabolic target important for p53 pro-survival function |
| Q28397372 | Anoikis resistance: an essential prerequisite for tumor metastasis |
| Q38761246 | Anti-proliferative Effect of Physcion on Human Gastric Cell Line via Inducing ROS-Dependent Apoptosis |
| Q36675898 | Anticancer Properties of PPARalpha-Effects on Cellular Metabolism and Inflammation |
| Q37564590 | Aqueous Oldenlandia diffusa extracts inhibits colorectal cancer cells via activating AMP-activated protein kinase signalings |
| Q52889753 | Arginine starvation in colorectal carcinoma cells: Sensing, impact on translation control and cell cycle distribution. |
| Q36780387 | Association of AMP-activated protein kinase with risk and progression of non-Hodgkin lymphoma |
| Q85633241 | Association of digestive organ disease with metabolic syndrome: role of adipocytokine and its molecular mechanisms |
| Q47100126 | Augmented O-GlcNAcylation of AMP-activated kinase promotes the proliferation of LoVo cells, a colon cancer cell line |
| Q60935363 | Autophagic and Apoptotic Pathways as Targets for Chemotherapy in Glioblastoma |
| Q90311831 | Autophagy Modulators: Mechanistic Aspects and Drug Delivery Systems |
| Q38796071 | Autophagy and p53. |
| Q37732086 | Autophagy and the Cell Cycle: A Complex Landscape. |
| Q38816591 | Autophagy compensates impaired energy metabolism in CLPXP-deficient Podospora anserina strains and extends healthspan |
| Q36609833 | Autophagy induction extends lifespan and reduces lipid content in response to frataxin silencing in C. elegans |
| Q35232272 | Autophagy regulation in cancer development and therapy |
| Q36227227 | Autophagy releases lipid that promotes fibrogenesis by activated hepatic stellate cells in mice and in human tissues. |
| Q26865873 | Axis of ageing: telomeres, p53 and mitochondria |
| Q37566231 | BAD: undertaker by night, candyman by day. |
| Q37381555 | Balancing the decision of cell proliferation and cell fate |
| Q28391478 | Benzopyrene and experimental stressors cause compensatory differentiation in placental trophoblast stem cells |
| Q27303169 | Biogenesis and dynamics of mitochondria during the cell cycle: significance of 3'UTRs |
| Q64885849 | Blockage of glutamine-dependent anaplerosis affects mTORC1/2 activity and ultimately leads to cellular senescence-like response. |
| Q50561688 | Blocking the utilization of glucose induces the switch from senescence to apoptosis in pseudolaric acid B-treated human lung cancer cells in vitro. |
| Q30484041 | Brain-derived neurotrophic factor functions as a metabotrophin to mediate the effects of exercise on cognition |
| Q36425522 | C. elegans AMPKs promote survival and arrest germline development during nutrient stress |
| Q38859558 | C6 ceramide dramatically increases vincristine sensitivity both in vivo and in vitro, involving AMP-activated protein kinase-p53 signaling |
| Q27317294 | CEP-1, the Caenorhabditis elegans p53 homolog, mediates opposing longevity outcomes in mitochondrial electron transport chain mutants |
| Q90236813 | CPT1 regulates the proliferation of pulmonary artery smooth muscle cells through the AMPK-p53-p21 pathway in pulmonary arterial hypertension |
| Q59792823 | Caffeine Protects Skin from Oxidative Stress-Induced Senescence through the Activation of Autophagy |
| Q44603723 | Calcium/calmodulin-dependent kinase kinase 2 regulates hematopoietic stem and progenitor cell regeneration |
| Q41982167 | Can metabolic plasticity be a cause for cancer? Warburg-Waddington legacy revisited. |
| Q38046274 | Cancer cell metabolism: one hallmark, many faces. |
| Q35723836 | Cancer metabolism: current perspectives and future directions |
| Q36401243 | Cancer's sweet tooth: the Janus effect of glucose metabolism in tumorigenesis |
| Q39100207 | Capsaicin induces apoptosis in human osteosarcoma cells through AMPK-dependent and AMPK-independent signaling pathways |
| Q93080654 | Capsaicin: Effects on the Pathogenesis of Hepatocellular Carcinoma |
| Q35861635 | Carbon source metabolism and its regulation in cancer cells |
| Q47265220 | Cardiac-specific ablation of the E3 ubiquitin ligase Mdm2 leads to oxidative stress, broad mitochondrial deficiency and early death |
| Q34976658 | Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress |
| Q42316726 | Celecoxib inhibits proliferation and survival of chronic myelogeous leukemia (CML) cells via AMPK-dependent regulation of β-catenin and mTORC1/2. |
| Q28383069 | Cell cycle arrest and cell survival induce reverse trends of cardiolipin remodeling |
| Q37035849 | Cell cycle arrest in Metformin treated breast cancer cells involves activation of AMPK, downregulation of cyclin D1, and requires p27Kip1 or p21Cip1. |
| Q42592610 | Cell cycle progression is regulated by intertwined redox oscillators |
| Q34440592 | Cell metabolism: an essential link between cell growth and apoptosis |
| Q28081013 | Cellular and molecular biology of aging endothelial cells |
| Q27013561 | Cellular and molecular mechanisms of metformin: an overview |
| Q38896922 | Cellular lifespan and senescence: a complex balance between multiple cellular pathways |
| Q35915928 | Cellular metabolism and disease: what do metabolic outliers teach us? |
| Q64272067 | Cellular senescence: a promising strategy for cancer therapy |
| Q28254513 | Chemical genetic screen for AMPKα2 substrates uncovers a network of proteins involved in mitosis |
| Q39261999 | Chemotherapeutic agents induce the expression and activity of their clearing enzyme CYP3A4 by activating p53. |
| Q28389330 | Chemotherapy Drug Induced Discoordination of Mitochondrial Life Cycle Detected by Cardiolipin Fluctuation |
| Q28481422 | Chlorogenic acid stimulates glucose transport in skeletal muscle via AMPK activation: a contributor to the beneficial effects of coffee on diabetes |
| Q26749399 | Circulating adiponectin levels in various malignancies: an updated meta-analysis of 107 studies |
| Q46291702 | Citrobacter rodentium Subverts ATP Flux and Cholesterol Homeostasis in Intestinal Epithelial Cells In Vivo |
| Q37820312 | Clinical and molecular insights into tuberous sclerosis complex renal disease. |
| Q49358639 | Clinorotation-induced autophagy via HDM2-p53-mTOR pathway enhances cell migration in vascular endothelial cells |
| Q38748407 | Co-exposure to amorphous silica nanoparticles and benzo[a]pyrene at low level in human bronchial epithelial BEAS-2B cells |
| Q27323698 | Cofilin/Twinstar phosphorylation levels increase in response to impaired coenzyme a metabolism |
| Q91669823 | Combination therapy with androgen deprivation for hormone sensitive prostate cancer: A new frontier |
| Q92756232 | Compound C Inhibits B16-F1 Tumor Growth in a Syngeneic Mouse Model Via the Blockage of Cell Cycle Progression and Angiogenesis |
| Q61965595 | Comprehensive evaluation of coding region point mutations in microsatellite‐unstable colorectal cancer |
| Q40811649 | Constitutive mTOR activation in TSC mutants sensitizes cells to energy starvation and genomic damage via p53. |
| Q58805589 | Control of metabolism by p53 - Cancer and beyond |
| Q39967749 | Coordination of mitochondrial bioenergetics with G1 phase cell cycle progression |
| Q38984847 | Critical role for p53-serine 15 phosphorylation in stimulating transactivation at p53-responsive promoters |
| Q46976979 | Cryptotanshinone induces G1 cell cycle arrest and autophagic cell death by activating the AMP-activated protein kinase signal pathway in HepG2 hepatoma |
| Q92359638 | Curcumin induces multiple signaling pathways leading to vascular smooth muscle cell senescence |
| Q34556943 | Cyclin D1 Restrains Oncogene-Induced Autophagy by Regulating the AMPK-LKB1 Signaling Axis. |
| Q35070938 | Cyclin D1 determines mitochondrial function in vivo |
| Q34299294 | Cytosolic malate dehydrogenase regulates senescence in human fibroblasts. |
| Q35940027 | Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapy |
| Q33314701 | DAPK-1 binding to a linear peptide motif in MAP1B stimulates autophagy and membrane blebbing. |
| Q33740063 | DNA damage related crosstalk between the nucleus and mitochondria |
| Q34720959 | DNA replication stress, genome instability and aging |
| Q36906231 | DNA replication stress-induced loss of reproductive capacity in S. cerevisiae and its inhibition by caloric restriction |
| Q38162438 | Dealing with hunger: Metabolic stress responses in tumors |
| Q35801388 | Deconvoluting mTOR biology |
| Q51825409 | Defining the pathogenicity of creatine deficiency syndrome. |
| Q42276010 | Degradation of AMPK by a cancer-specific ubiquitin ligase |
| Q33697747 | Delayed correlation of mRNA and protein expression in rapamycin-treated cells and a role for Ggc1 in cellular sensitivity to rapamycin |
| Q36557347 | Deoxypodophyllotoxin suppresses tumor vasculature in HUVECs by promoting cytoskeleton remodeling through LKB1-AMPK dependent Rho A activatio |
| Q36678362 | Depletion of the novel p53-target gene carnitine palmitoyltransferase 1C delays tumor growth in the neurofibromatosis type I tumor model |
| Q36813221 | Deubiquitination and Activation of AMPK by USP10 |
| Q36475846 | Developing a head for energy sensing: AMP-activated protein kinase as a multifunctional metabolic sensor in the brain |
| Q33316556 | Development of a human mitochondrial oligonucleotide microarray (h-MitoArray) and gene expression analysis of fibroblast cell lines from 13 patients with isolated F1Fo ATP synthase deficiency. |
| Q34017353 | Development of head organizer of the mouse embryo depends on a high level of mitochondrial metabolism |
| Q43255957 | Development of hepatic fibrosis occurs normally in AMPK-deficient mice |
| Q38003249 | Developmental decisions: balancing genetics and the environment by C. elegans |
| Q90687221 | Dichloroacetic acid (DCA) synergizes with the SIRT2 inhibitor Sirtinol and AGK2 to enhance anti-tumor efficacy in non-small cell lung cancer |
| Q54631030 | Diet and tumor LKB1 expression interact to determine sensitivity to anti-neoplastic effects of metformin in vivo. |
| Q33587322 | Dietary curcumin supplementation counteracts reduction in levels of molecules involved in energy homeostasis after brain trauma |
| Q36556345 | Dietary downregulation of mutant p53 levels via glucose restriction: mechanisms and implications for tumor therapy |
| Q47861796 | Differences in p53 status significantly influence the cellular response and cell survival to 1,25-dihydroxyvitamin D3-metformin cotreatment in colorectal cancer cells. |
| Q38954598 | Differential effects of AMPK agonists on cell growth and metabolism |
| Q37543714 | Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK. |
| Q34049279 | Disruption of G1-phase phospholipid turnover by inhibition of Ca2+-independent phospholipase A2 induces a p53-dependent cell-cycle arrest in G1 phase |
| Q33682914 | Dissecting the role of AMP-activated protein kinase in human diseases |
| Q36117542 | Distinct p53 acetylation cassettes differentially influence gene-expression patterns and cell fate. |
| Q57809462 | Do polymorphisms in protein kinase catalytic subunit alpha-1 gene associated with cancer susceptibility? a meta-analysis and systematic review |
| Q39845982 | Down-regulation of AMP-activated protein kinase sensitizes DU145 carcinoma to Fas-induced apoptosis via c-FLIP degradation |
| Q39222558 | Down-regulation of adenosine monophosphate-activated protein kinase activity: A driver of cancer |
| Q38150426 | Doxorubicin-induced death in tumour cells and cardiomyocytes: is autophagy the key to improving future clinical outcomes? |
| Q64107799 | Drugging in the absence of p53 |
| Q35613319 | Dual inhibition of tumor energy pathway by 2-deoxyglucose and metformin is effective against a broad spectrum of preclinical cancer models |
| Q38327525 | Dysregulated glycolysis as an oncogenic event |
| Q91750497 | Dysregulation of Glucose Metabolism by Oncogenes and Tumor Suppressors in Cancer Cells |
| Q58091174 | Effect of ghost pepper on cell proliferation, apoptosis, senescence and global proteomic profile in human renal adenocarcinoma cells |
| Q54565254 | Effects of DPP-4 inhibition on cardiac metabolism and function in mice. |
| Q39043221 | Effects of metformin on breast cancer cell proliferation, the AMPK pathway and the cell cycle |
| Q36203076 | Elongation of Long-Chain Fatty Acid Family Member 6 (Elovl6)-Driven Fatty Acid Metabolism Regulates Vascular Smooth Muscle Cell Phenotype Through AMP-Activated Protein Kinase/Krüppel-Like Factor 4 (AMPK/KLF4) Signaling |
| Q90446586 | Embigin Promotes Prostate Cancer Progression by S100A4-Dependent and-Independent Mechanisms |
| Q52727888 | Emerging Roles of p53 Family Members in Glucose Metabolism. |
| Q99402564 | Emerging Roles of the MAGE Protein Family in Stress Response Pathways |
| Q37666015 | Emerging roles of p53 and other tumour-suppressor genes in immune regulation |
| Q37745507 | Endogenous AMPK acts as a detrimental factor in fulminant hepatitis via potentiating JNK-dependent hepatocyte apoptosis |
| Q34148526 | Energy metabolism in adult neural stem cell fate |
| Q26770341 | Energy metabolism in neuroblastoma and Wilms tumor |
| Q36340092 | Estrogen deprivation and excess energy supply accelerate 7,12-dimethylbenz(a)anthracene-induced mammary tumor growth in C3H/HeN mice |
| Q55069976 | Evaluation of Novel N-(piperidine-4-yl)benzamide Derivatives as Potential Cell Cycle Inhibitors in HepG2 Cells. |
| Q41435904 | Evidence for biological effects of metformin in operable breast cancer: biomarker analysis in a pre-operative window of opportunity randomized trial |
| Q39662076 | Exogenous cell-permeable C6 ceramide sensitizes multiple cancer cell lines to Doxorubicin-induced apoptosis by promoting AMPK activation and mTORC1 inhibition |
| Q35679387 | Exploring long-term protection of normal human fibroblasts and epithelial cells from chemotherapy in cell culture |
| Q36853115 | Expression of CD39 on Activated T Cells Impairs their Survival in Older Individuals |
| Q44800847 | Expression of cell proliferation cycle negative regulators in fibroblasts of an ischemic diabetic foot ulcer. A clinical case report. |
| Q24652381 | Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted |
| Q39115386 | Extra-low-frequency magnetic fields alter cancer cells through metabolic restriction |
| Q33815880 | Extracellular cystatin SN and cathepsin B prevent cellular senescence by inhibiting abnormal glycogen accumulation |
| Q38845499 | Fatsioside A‑induced apoptotic death of HepG2 cells requires activation of AMP‑activated protein kinase |
| Q37092037 | Fatty acid degradation plays an essential role in proliferation of mouse female primordial germ cells via the p53-dependent cell cycle regulation. |
| Q57475967 | Finely-tuned regulation of AMP-activated protein kinase (AMPK) is crucial for human adult erythropoiesis |
| Q37106662 | Follicle-stimulating hormone inhibits adenosine 5'-monophosphate-activated protein kinase activation and promotes cell proliferation of primary granulosa cells in culture through an Akt-dependent pathway |
| Q37015516 | From Ancient Pathways to Aging Cells-Connecting Metabolism and Cellular Senescence |
| Q36292868 | Fuel feeds function: energy metabolism and the T-cell response |
| Q27025284 | Fueling immunity: insights into metabolism and lymphocyte function |
| Q51024961 | Function of specialized regulatory proteins and signaling pathways in exercise-induced muscle mitochondrial biogenesis. |
| Q38807302 | Functional characterization of AMP-activated protein kinase signaling in tumorigenesis |
| Q38106130 | Furthering the design and the discovery of small molecule ATP-competitive mTOR inhibitors as an effective cancer treatment |
| Q39739729 | Fyn-phosphorylated PIKE-A binds and inhibits AMPK signaling, blocking its tumor suppressive activity |
| Q37426264 | GAMT, a p53-inducible modulator of apoptosis, is critical for the adaptive response to nutrient stress |
| Q41046980 | Gain-of-function mutant p53 promotes cell growth and cancer cell metabolism via inhibition of AMPK activation. |
| Q38217467 | Gene of the month. AMP kinase (PRKAA1). |
| Q33901605 | Germ-line variation at a functional p53 binding site increases susceptibility to breast cancer development |
| Q34158129 | Germline variation in TP53 regulatory network genes associates with breast cancer survival and treatment outcome |
| Q36850426 | Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses |
| Q36708904 | Glucagon-like peptide-1 prevents methylglyoxal-induced apoptosis of beta cells through improving mitochondrial function and suppressing prolonged AMPK activation |
| Q41427795 | Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells |
| Q37620721 | Glucose metabolism and hexosamine pathway regulate oncogene-induced senescence. |
| Q24643422 | Glucose metabolism attenuates p53 and Puma-dependent cell death upon growth factor deprivation |
| Q37973332 | Glucose signaling-mediated coordination of cell growth and cell cycle in Saccharomyces cerevisiae. |
| Q55712083 | Glucose starvation induces LKB1-AMPK-mediated MMP-9 expression in cancer cells. |
| Q34348701 | Glucose substitution prolongs maintenance of energy homeostasis and lifespan of telomere dysfunctional mice |
| Q38947274 | Glucose transporter 1-mediated glucose uptake is limiting for B-cell acute lymphoblastic leukemia anabolic metabolism and resistance to apoptosis. |
| Q36995837 | Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways. |
| Q93047778 | Glucose-dependent GPER1 expression modulates tamoxifen-induced IGFBP-1 accumulation |
| Q37596851 | Glutamine sensitivity analysis identifies the xCT antiporter as a common triple-negative breast tumor therapeutic target |
| Q35857078 | Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1. |
| Q34361242 | Growth signaling promotes chronological aging in budding yeast by inducing superoxide anions that inhibit quiescence |
| Q37352957 | Guardian of corpulence: a hypothesis on p53 signaling in the fat cell |
| Q36195037 | Hepatoma cells from mice deficient in glycine N-methyltransferase have increased RAS signaling and activation of liver kinase B1. |
| Q40020653 | High molecular weight adiponectin inhibits proliferation of hepatic stellate cells via activation of adenosine monophosphate-activated protein kinase |
| Q37107268 | Homeostatic functions of the p53 tumor suppressor: regulation of energy metabolism and antioxidant defense |
| Q27003901 | Hormesis in aging and neurodegeneration-a prodigy awaiting dissection |
| Q98166067 | How do cancer cells replenish their fuel supply? |
| Q38116857 | How metabolism generates signals during innate immunity and inflammation. |
| Q41913041 | Human embryonic and induced pluripotent stem cells maintain phenotype but alter their metabolism after exposure to ROCK inhibitor. |
| Q38958241 | Human mitochondrial NAD(P)(+)-dependent malic enzyme participates in cutaneous melanoma progression and invasion |
| Q24625882 | Human pyruvate kinase M2: a multifunctional protein |
| Q34627179 | Hunk is required for HER2/neu-induced mammary tumorigenesis |
| Q26787065 | Hydrogen peroxide - production, fate and role in redox signaling of tumor cells |
| Q37123940 | Hyperoxia-induced premature senescence requires p53 and pRb, but not mitochondrial matrix ROS. |
| Q51451285 | Hypoglycemia Enhances Epithelial-Mesenchymal Transition and Invasiveness, and Restrains the Warburg Phenotype, in Hypoxic HeLa Cell Cultures and Microspheroids. |
| Q92918176 | Hypoxia and aging |
| Q36895405 | Hypoxia, glucose metabolism and the Warburg's effect. |
| Q35155445 | Hypoxia-induced energy stress regulates mRNA translation and cell growth |
| Q24302481 | IFI16 induction by glucose restriction in human fibroblasts contributes to autophagy through activation of the ATM/AMPK/p53 pathway |
| Q28553394 | Identification of KCa3.1 Channel as a Novel Regulator of Oxidative Phosphorylation in a Subset of Pancreatic Carcinoma Cell Lines |
| Q38304316 | Identification of a dominant negative functional domain on DAPK-1 that degrades DAPK-1 protein and stimulates TNFR-1-mediated apoptosis |
| Q52659506 | Identification of a novel 2-oxindole fluorinated derivative as in vivo antitumor agent for prostate cancer acting via AMPK activation. |
| Q35000816 | Identification of a novel AMPK-PEA15 axis in the anoikis-resistant growth of mammary cells. |
| Q36493649 | Identification of aneuploidy-selective antiproliferation compounds |
| Q38851848 | Immature Colon Carcinoma Transcript 1 Is Essential for Prostate Cancer Cell Viability and Proliferation |
| Q33800755 | Impact of Aging and Exercise on Mitochondrial Quality Control in Skeletal Muscle |
| Q39863992 | Inactivation of AMPK alters gene expression and promotes growth of prostate cancer cells. |
| Q28513487 | Inactivation of S6 ribosomal protein gene in T lymphocytes activates a p53-dependent checkpoint response. |
| Q38759079 | Independent AMP and NAD signaling regulates C2C12 differentiation and metabolic adaptation |
| Q39428439 | Induction of autophagy in hepatocellular carcinoma cells by SB203580 requires activation of AMPK and DAPK but not p38 MAPK. |
| Q41768449 | Induction of autophagy supports the bioenergetic demands of quiescent muscle stem cell activation |
| Q38310171 | Induction of transcription factor CEBP homology protein mediates hypoglycaemia-induced necrotic cell death in human neuroblastoma cells |
| Q37418190 | Influence of anthropometric factors on tumour biological characteristics of colorectal cancer in men and women: a cohort study |
| Q38752920 | Inhibiting Mitochondrial DNA Ligase IIIα Activates Caspase 1-Dependent Apoptosis in Cancer Cells |
| Q40051802 | Inhibition of AMP-activated protein kinase protects pancreatic beta-cells from cytokine-mediated apoptosis and CD8+ T-cell-induced cytotoxicity. |
| Q40035672 | Inhibition of AMP-activated protein kinase sensitizes cancer cells to cisplatin-induced apoptosis via hyper-induction of p53. |
| Q35868154 | Inhibition of AMP-activated protein kinase α (AMPKα) by doxorubicin accentuates genotoxic stress and cell death in mouse embryonic fibroblasts and cardiomyocytes: role of p53 and SIRT1. |
| Q57110813 | Inhibition of Casein Kinase 2 Protects Oligodendrocytes From Excitotoxicity by Attenuating JNK/p53 Signaling Cascade |
| Q39852820 | Inhibition of de novo purine synthesis in human prostate cells results in ATP depletion, AMPK activation and induces senescence |
| Q34042731 | Inhibition of polo-like kinase 1 (Plk1) enhances the antineoplastic activity of metformin in prostate cancer |
| Q38503112 | Inhibitory effect of (-)-epigallocatechin-3-gallate on lipid accumulation of 3T3-L1 cells |
| Q28072521 | Insulin-Sensitizers, Polycystic Ovary Syndrome and Gynaecological Cancer Risk |
| Q39096530 | Integrins and Cell Metabolism: An Intimate Relationship Impacting Cancer |
| Q40185102 | Interference with energy metabolism by 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside induces HPV suppression in cervical carcinoma cells and apoptosis in the absence of LKB1. |
| Q37022223 | Inverse agonist of estrogen-related receptor α suppresses the growth of triple negative breast cancer cells through ROS generation and interaction with multiple cell signaling pathways |
| Q38849601 | Involvement of AMP-activated protein kinase in mediating pyrrolo-1,5-benzoxazepine-induced apoptosis in neuroblastoma cells |
| Q54514341 | Involvement of AMPK and MAPK signaling during the progression of experimental autoimmune myocarditis in rats and its blockade using a novel antioxidant. |
| Q37305385 | Is cancer a disease of abnormal cellular metabolism? New angles on an old idea |
| Q38215034 | Is it time to test biguanide metformin in the treatment of melanoma? |
| Q37615064 | Is p53 Involved in Tissue-Specific Insulin Resistance Formation? |
| Q28817206 | Isoorientin induces apoptosis, decreases invasiveness, and downregulates VEGF secretion by activating AMPK signaling in pancreatic cancer cells |
| Q47156516 | Jujube leaf green tea extracts inhibits hepatocellular carcinoma cells by activating AMPK. |
| Q52691555 | KRAB-type zinc-finger proteins PITA and PISA specifically regulate p53-dependent glycolysis and mitochondrial respiration. |
| Q45175810 | Kaempferol induces autophagic cell death of hepatocellular carcinoma cells via activating AMPK signaling |
| Q33392580 | Kinase activity-independent suppression of p73alpha by AMP-activated kinase alpha (AMPKalpha). |
| Q39313598 | Kinase suppressor of Ras 2 (KSR2) regulates tumor cell transformation via AMPK |
| Q37383513 | LKB1 and AMP-activated protein kinase control of mTOR signalling and growth |
| Q34669215 | LKB1 and AMPK and the cancer-metabolism link - ten years after |
| Q38034266 | LKB1 and AMPK: central regulators of lymphocyte metabolism and function |
| Q37850361 | LKB1 in lung cancerigenesis: a serine/threonine kinase as tumor suppressor |
| Q35226548 | LKB1 reduces ROS-mediated cell damage via activation of p38. |
| Q36865568 | LKB1/STK11 inactivation leads to expansion of a prometastatic tumor subpopulation in melanoma |
| Q37333592 | LKB1; linking cell structure and tumor suppression |
| Q41619824 | Lack of chemopreventive efficacy of metformin in rodent models of urinary bladder, head and neck, and colon/intestine cancer |
| Q34993832 | Large-scale cytological profiling for functional analysis of bioactive compounds. |
| Q55350394 | Liver kinase B1/adenosine monophosphate-activated protein kinase signaling axis induces p21/WAF1 expression in a p53-dependent manner. |
| Q37589839 | Liver p53 is stabilized upon starvation and required for amino acid catabolism and gluconeogenesis |
| Q91286534 | Lnc-THOR silencing inhibits human glioma cell survival by activating MAGEA6-AMPK signaling |
| Q34998627 | Long-term use of metformin and colorectal cancer risk in type II diabetics: a population-based case-control study |
| Q34717352 | Loss of abhd5 promotes colorectal tumor development and progression by inducing aerobic glycolysis and epithelial-mesenchymal transition |
| Q34409141 | Loss of p53 induces cell proliferation via Ras-independent activation of the Raf/Mek/Erk signaling pathway |
| Q37599925 | Loss of the tumor suppressor LKB1 promotes metabolic reprogramming of cancer cells via HIF-1α. |
| Q38610330 | Lysosomotropism depends on glucose: a chloroquine resistance mechanism |
| Q35188786 | MIF family members cooperatively inhibit p53 expression and activity |
| Q39262984 | MYC and AMPK-Save Energy or Die! |
| Q35153207 | Maintenance of mouse hematopoietic stem cells ex vivo by reprogramming cellular metabolism |
| Q24302448 | Mammalian polynucleotide phosphorylase is an intermembrane space RNase that maintains mitochondrial homeostasis |
| Q37670612 | Mammalian target of rapamycin complex 2 (mTORC2) coordinates pulmonary artery smooth muscle cell metabolism, proliferation, and survival in pulmonary arterial hypertension |
| Q36640334 | Matched and mismatched metabolic fuels in lymphocyte function |
| Q47817362 | Maternal high-fat diet consumption enhances offspring susceptibility to DSS-induced colitis in mice. |
| Q37020571 | Mechanisms and methods in glucose metabolism and cell death |
| Q88712420 | Mechanisms of skeletal muscle wasting in a mouse model for myotonic dystrophy type 1 |
| Q43855228 | Medically managed hypercholesterolemia and insulin-dependent diabetes mellitus preoperatively predicts poor survival after surgery for pancreatic cancer |
| Q38969211 | Metabolic Regulation of Apoptosis in Cancer. |
| Q39297355 | Metabolic Reprogramming in Glioma. |
| Q91975334 | Metabolic Reprogramming in Triple-Negative Breast Cancer |
| Q90288192 | Metabolic aspects in NAFLD, NASH and hepatocellular carcinoma: the role of PGC1 coactivators |
| Q35928543 | Metabolic consideration of epiphyseal growth: survival responses in a taxing environment |
| Q38442728 | Metabolic control of signalling pathways and metabolic auto-regulation |
| Q38181405 | Metabolic implication of tumor:stroma crosstalk in breast cancer |
| Q39546982 | Metabolic oxidative stress elicited by the copper(II) complex [Cu(isaepy)2] triggers apoptosis in SH-SY5Y cells through the induction of the AMP-activated protein kinase/p38MAPK/p53 signalling axis: evidence for a combined use with 3-bromopyruvate i |
| Q37077388 | Metabolic plasticity and hematopoietic stem cell biology |
| Q37298047 | Metabolic regulation by p53 family members. |
| Q37845740 | Metabolic regulation by p53. |
| Q36783485 | Metabolic regulation by the mitochondrial phosphatase PTPMT1 is required for hematopoietic stem cell differentiation |
| Q37333099 | Metabolic regulation of the cell cycle |
| Q34482056 | Metabolic reprogramming and dysregulated metabolism: cause, consequence and/or enabler of environmental carcinogenesis? |
| Q27002421 | Metabolic reprogramming as a novel regulator of skeletal muscle development and regeneration |
| Q37974518 | Metabolic reprogramming of the tumor. |
| Q99629120 | Metabolic reprogramming sustains cancer cell survival following extracellular matrix detachment |
| Q29617612 | Metabolic reprogramming: a cancer hallmark even warburg did not anticipate |
| Q39441847 | Metabolic restriction of cancer cells in vitro causes karyotype contraction--an indicator of cancer promotion? |
| Q38171577 | Metabolic stress and cancer: is autophagy the common denominator and a feasible target? |
| Q36192905 | Metabolic stress in autophagy and cell death pathways |
| Q38074586 | Metabolism of inflammation limited by AMPK and pseudo-starvation |
| Q35031827 | Metabolite and transcriptome analysis during fasting suggest a role for the p53-Ddit4 axis in major metabolic tissues |
| Q28551227 | Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis |
| Q49887272 | Metformin Enhanced in Vitro Radiosensitivity Associates with G2/M Cell Cycle Arrest and Elevated Adenosine-5'-monophosphate-activated Protein Kinase Levels in Glioblastoma |
| Q35702142 | Metformin Induced AMPK Activation, G0/G1 Phase Cell Cycle Arrest and the Inhibition of Growth of Esophageal Squamous Cell Carcinomas In Vitro and In Vivo |
| Q93059348 | Metformin Modulates Cyclin D1 and P53 Expression to Inhibit Cell Proliferation and to Induce Apoptosis in Cervical Cancer Cell Lines |
| Q48831355 | Metformin Promotes AMP-activated Protein Kinase-independent Suppression of ΔNp63α Protein Expression and Inhibits Cancer Cell Viability |
| Q36078840 | Metformin Treatment for the Prevention and/or Treatment of Breast/Mammary Tumorigenesis |
| Q33890763 | Metformin against cancer stem cells through the modulation of energy metabolism: special considerations on ovarian cancer |
| Q43015031 | Metformin and cancer: licence to heal? |
| Q37837675 | Metformin and cancer: new applications for an old drug |
| Q64103318 | Metformin and glucose starvation decrease the migratory ability of hepatocellular carcinoma cells: targeting AMPK activation to control migration |
| Q38415035 | Metformin attenuates graft-versus-host disease via restricting mammalian target of rapamycin/signal transducer and activator of transcription 3 and promoting adenosine monophosphate-activated protein kinase-autophagy for the balance between T helper |
| Q37293802 | Metformin attenuates ovarian cancer cell growth in an AMP-kinase dispensable manner |
| Q37313880 | Metformin displays in vitro and in vivo antitumor effect against osteosarcoma |
| Q33683560 | Metformin disrupts malignant behavior of oral squamous cell carcinoma via a novel signaling involving Late SV40 factor/Aurora-A. |
| Q39340562 | Metformin elicits anticancer effects through the sequential modulation of DICER and c-MYC. |
| Q39583558 | Metformin exposure affects human and mouse fetal testicular cells. |
| Q36297833 | Metformin in non-diabetic patients presenting with ST elevation myocardial infarction: rationale and design of the glycometabolic intervention as adjunct to primary percutaneous intervention in ST elevation myocardial infarction (GIPS)-III trial |
| Q61796175 | Metformin inhibits lithocholic acid-induced interleukin 8 upregulation in colorectal cancer cells by suppressing ROS production and NF-kB activity |
| Q35269865 | Metformin inhibits melanoma development through autophagy and apoptosis mechanisms. |
| Q38682430 | Metformin is associated with fewer major adverse cardiac events among patients with a new diagnosis of type 2 diabetes mellitus: A propensity score-matched nationwide study |
| Q35793665 | Metformin prevents aggressive ovarian cancer growth driven by high-energy diet: similarity with calorie restriction |
| Q36361245 | Metformin produces growth inhibitory effects in combination with nutlin-3a on malignant mesothelioma through a cross-talk between mTOR and p53 pathways |
| Q50742738 | Metformin reduces TGF-β1-induced extracellular matrix production in nasal polyp-derived fibroblasts. |
| Q37582441 | Metformin suppresses adipogenesis through both AMP-activated protein kinase (AMPK)-dependent and AMPK-independent mechanisms |
| Q58790135 | Metformin, an Anti-diabetic Drug to Target Leukemia |
| Q58728932 | Metformin: Focus on Melanoma |
| Q37608817 | Metformin: On Ongoing Journey across Diabetes, Cancer Therapy and Prevention |
| Q37728510 | Methotrexate and 5-aminoimidazole-4-carboxamide riboside exert synergistic anticancer action against human breast cancer and hepatocellular carcinoma. |
| Q38695207 | Methyl pyruvate protects a normal lung fibroblast cell line from irinotecan-induced cell death: Potential use as adjunctive to chemotherapy. |
| Q100750272 | MicroRNA dynamics during hibernation of the Australian central bearded dragon (Pogona vitticeps) |
| Q33635798 | Minireview: Obesity and breast cancer: a tale of inflammation and dysregulated metabolism |
| Q36557994 | Mitochondria and cancer: is there a morphological connection? |
| Q37535535 | Mitochondria and energetic depression in cell pathophysiology |
| Q38647795 | Mitochondria and the hallmarks of cancer. |
| Q37970025 | Mitochondria at the interface between danger signaling and metabolism: role of unfolded protein responses in chronic inflammation |
| Q49748248 | Mitochondrial (Dys) Function in Inflammaging: Do MitomiRs Influence the Energetic, Oxidative, and Inflammatory Status of Senescent Cells? |
| Q36568015 | Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype |
| Q37408996 | Mitochondrial Ribosomal Protein L10 Associates with Cyclin B1/Cdk1 Activity and Mitochondrial Function |
| Q39294200 | Mitochondrial determinants of cancer health disparities |
| Q39837656 | Mitochondrial dysfunction contributes to oncogene-induced senescence. |
| Q58556263 | Mitochondrial dysfunction in cancer |
| Q35027745 | Mitochondrial effectors of cellular senescence: beyond the free radical theory of aging |
| Q38128781 | Mitochondrial fission-fusion as an emerging key regulator of cell proliferation and differentiation |
| Q30581882 | Mitochondrial hyperfusion induced by loss of the fission protein Drp1 causes ATM-dependent G2/M arrest and aneuploidy through DNA replication stress |
| Q24311397 | Mitochondrial pyrimidine nucleotide carrier (PNC1) regulates mitochondrial biogenesis and the invasive phenotype of cancer cells |
| Q37941864 | Mitochondrial regulation of cell cycle and proliferation |
| Q30458185 | Mitochondrial stress engages E2F1 apoptotic signaling to cause deafness |
| Q40030805 | Mitochondrial stress-induced p53 attenuates HIF-1α activity by physical association and enhanced ubiquitination |
| Q24644257 | Modulation of intracellular ROS levels by TIGAR controls autophagy |
| Q36023587 | Molecular Pathways: Is AMPK a Friend or a Foe in Cancer? |
| Q26770105 | Molecular Regulation of Adipogenesis and Potential Anti-Adipogenic Bioactive Molecules |
| Q47896414 | Molecular mechanisms of LKB1 induced cell cycle arrest |
| Q37824725 | Molecular mechanisms of tumor suppression by LKB1. |
| Q24620628 | Molecular pathological epidemiology of colorectal neoplasia: an emerging transdisciplinary and interdisciplinary field |
| Q36436702 | Mouse bites dogma: how mouse models are changing our views of how P53 is regulated in vivo |
| Q33554797 | Multifaceted roles of adiponectin in cancer |
| Q36033101 | Murine protein serine-threonine kinase 38 activates p53 function through Ser15 phosphorylation |
| Q38587970 | Muscle wasting as main evidence of energy impairment in cancer cachexia: future therapeutic approaches |
| Q37065314 | Mutation of Fnip1 is associated with B-cell deficiency, cardiomyopathy, and elevated AMPK activity. |
| Q36855285 | Myc-induced AMPK-phospho p53 pathway activates Bak to sensitize mitochondrial apoptosis |
| Q91691824 | NAD+ metabolism governs the proinflammatory senescence-associated secretome |
| Q33925325 | NDRG2 overexpression enhances glucose deprivation-mediated apoptosis in breast cancer cells via inhibition of the LKB1-AMPK pathway |
| Q36291524 | NF-κB controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration |
| Q38134102 | NLRP3 and IL-1β in macrophages as critical regulators of metabolic diseases |
| Q42549741 | NUAK1 links genomic instability and senescence. |
| Q35787759 | Nanocurcumin Prevents Hypoxia Induced Stress in Primary Human Ventricular Cardiomyocytes by Maintaining Mitochondrial Homeostasis. |
| Q92751113 | Nectandrin B-mediated activation of the AMPK pathway prevents cellular senescence in human diploid fibroblasts by reducing intracellular ROS levels |
| Q36368238 | Negative regulation of AMP-activated protein kinase (AMPK) activity by macrophage migration inhibitory factor (MIF) family members in non-small cell lung carcinomas |
| Q38389967 | New perspective on targeting the tumor suppressor p53 pathway in the tumor microenvironment to enhance the efficacy of immunotherapy. |
| Q34685830 | New plays in the p53 theater |
| Q92340915 | Nitrogen-dependent coordination of cell cycle, quiescence and TAG accumulation in Chlamydomonas |
| Q35907038 | Novel epigallocatechin gallate (EGCG) analogs activate AMP-activated protein kinase pathway and target cancer stem cells |
| Q24299137 | Novel nucleolar pathway connecting intracellular energy status with p53 activation |
| Q36683880 | Nuclear receptors and the Warburg effect in cancer |
| Q35252465 | Nutrient starvation affects expression of LC3 family at the feto-maternal interface during murine placentation |
| Q39663338 | Nutrient withdrawal rescues growth factor-deprived cells from mTOR-dependent damage |
| Q93016604 | Nutritional Stress in Head and Neck Cancer Originating Cell Lines: The Sensitivity of the NRF2-NQO1 Axis |
| Q37274568 | Oncogenic B-RAF negatively regulates the tumor suppressor LKB1 to promote melanoma cell proliferation |
| Q42590448 | Opposing function of mitochondrial prohibitin in aging. |
| Q38162447 | Optimizing intramuscular adaptations to aerobic exercise: effects of carbohydrate restriction and protein supplementation on mitochondrial biogenesis. |
| Q64923711 | Orange is the new black: Kinases are the new master regulators of tumor suppression. |
| Q61809550 | Oxygen in the tumor microenvironment: effects on dendritic cell function |
| Q92153225 | PARP1 Inhibition Augments UVB-Mediated Mitochondrial Changes-Implications for UV-Induced DNA Repair and Photocarcinogenesis |
| Q91657994 | PDK4-Deficiency Reprograms Intrahepatic Glucose and Lipid Metabolism to Facilitate Liver Regeneration in Mice |
| Q38711026 | PPARα regulates tumor cell proliferation and senescence via a novel target gene carnitine palmitoyltransferase 1C. |
| Q37371601 | PRKAA/AMPK restricts HBV replication through promotion of autophagic degradation |
| Q90313766 | PRKAA1 promotes proliferation and inhibits apoptosis of gastric cancer cells through activating JNK1 and Akt pathways |
| Q36432515 | PYCR1 and PYCR2 Interact and Collaborate with RRM2B to Protect Cells from Overt Oxidative Stress. |
| Q47745277 | Palbociclib-induced autophagy and senescence in gastric cancer cells |
| Q33664387 | Pannexin 3 regulates proliferation and differentiation of odontoblasts via its hemichannel activities |
| Q47958820 | Paraoxonase 2 Facilitates Pancreatic Cancer Growth and Metastasis by Stimulating GLUT1-Mediated Glucose Transport |
| Q89582628 | Pentatricopeptide repeat protein MID1 modulates nad2 intron 1 splicing and Arabidopsis development |
| Q37702988 | Perspectives of the AMP-activated kinase (AMPK) signalling pathway in thyroid cancer |
| Q36546637 | Pharmacologic regulation of AMPK in breast cancer affects cytoskeletal properties involved with microtentacle formation and re-attachment |
| Q64097637 | Pharmacological AMPK activation induces transcriptional responses congruent to exercise in skeletal and cardiac muscle, adipose tissues and liver |
| Q35832359 | Phenformin as prophylaxis and therapy in breast cancer xenografts |
| Q36573268 | Phosphatidylinositol ether lipid analogues induce AMP-activated protein kinase-dependent death in LKB1-mutant non small cell lung cancer cells |
| Q37482888 | Phosphorylation of BRAF by AMPK impairs BRAF-KSR1 association and cell proliferation |
| Q52375228 | Phosphorylation of CDC25C by AMP-activated protein kinase mediates a metabolic checkpoint during cell-cycle G2/M-phase transition. |
| Q28114977 | Phosphorylation of p53 by TAF1 inactivates p53-dependent transcription in the DNA damage response |
| Q26861053 | Plant sterols as anticancer nutrients: evidence for their role in breast cancer |
| Q44105853 | Polo-like kinase 1 coordinates biosynthesis during cell cycle progression by directly activating pentose phosphate pathway |
| Q42092020 | Positron emission tomography detection of human endothelial cell and fibroblast monolayers: effect of pretreament and cell density on 18FDG uptake. |
| Q33899450 | Posttranslational modification of p53: cooperative integrators of function |
| Q37123877 | Potential applications for biguanides in oncology |
| Q89144498 | Pro-tumorigenic AMPK in glioblastoma |
| Q35007074 | Prohibitin couples diapause signalling to mitochondrial metabolism during ageing in C. elegans |
| Q51427695 | Protein coingestion with alcohol following strenuous exercise attenuates alcohol-induced intramyocellular apoptosis and inhibition of autophagy. |
| Q35739018 | Protein kinase A contributes to the negative control of Snf1 protein kinase in Saccharomyces cerevisiae |
| Q37912205 | Proteomics revisits the cancer metabolome |
| Q39333766 | Quercetin enhances hypoxia-mediated apoptosis via direct inhibition of AMPK activity in HCT116 colon cancer |
| Q38619352 | Quercetin regulates the sestrin 2-AMPK-p38 MAPK signaling pathway and induces apoptosis by increasing the generation of intracellular ROS in a p53-independent manner |
| Q47232291 | ROS-Mediated Cell Cycle Arrest and Apoptosis Induced by Zearalenone in Mouse Sertoli Cells via ER Stress and the ATP/AMPK Pathway |
| Q48535054 | Radio-resistant Cervical Cancers Are Sensitive to Inhibition of Glycolysis and Redox Metabolism |
| Q39814876 | Re-sensitization of radiation resistant colorectal cancer cells to radiation through inhibition of AMPK pathway |
| Q42976643 | Re-thinking cell cycle regulators: the cross-talk with metabolism |
| Q34358845 | Recent progress on liver kinase B1 (LKB1): expression, regulation, downstream signaling and cancer suppressive function |
| Q35172644 | Reciprocal regulation of AMP-activated protein kinase and phospholipase D |
| Q40421522 | Reciprocal regulation of acetyl-CoA carboxylase 1 and senescence in human fibroblasts involves oxidant mediated p38 MAPK activation |
| Q24310386 | Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence |
| Q59812725 | Red pepper seed water extract inhibits preadipocyte differentiation and induces mature adipocyte apoptosis in 3T3-L1 cells |
| Q37093737 | Reduced activity of AMP-activated protein kinase protects against genetic models of motor neuron disease |
| Q96348276 | Regulating tumor suppressor genes: post-translational modifications |
| Q38884003 | Regulation of Cellular Metabolism and Hypoxia by p53. |
| Q39322285 | Regulation of Metabolic Activity by p53. |
| Q45316787 | Regulation of TP53 Activity through Phosphorylation |
| Q24651258 | Regulation of autophagy by cytoplasmic p53 |
| Q41889544 | Regulation of autophagy by glucose in Mammalian cells. |
| Q28303890 | Regulation of cancer cell metabolism |
| Q35612267 | Regulation of epithelial tight junction assembly and disassembly by AMP-activated protein kinase |
| Q24631421 | Regulation of glucose metabolism by p53: emerging new roles for the tumor suppressor |
| Q24548975 | Regulation of late G1/S phase transition and APC Cdh1 by reactive oxygen species |
| Q30499681 | Regulation of mitochondrial morphology by APC/CCdh1-mediated control of Drp1 stability |
| Q38693679 | Regulation of myoblast differentiation by metabolic perturbations induced by metformin. |
| Q24318723 | Regulation of ploidy and senescence by the AMPK-related kinase NUAK1 |
| Q33955739 | Regulation of the pentose phosphate pathway in cancer |
| Q27334113 | Relationship between mitochondrial electron transport chain dysfunction, development, and life extension in Caenorhabditis elegans |
| Q22250976 | Repurposing metformin: an old drug with new tricks in its binding pockets |
| Q41229658 | Requirement of the ATM/p53 tumor suppressor pathway for glucose homeostasis |
| Q86655110 | Resistance exercise with low glycogen increases p53 phosphorylation and PGC-1α mRNA in skeletal muscle |
| Q39156783 | Resveratrol enhances prostate cancer cell response to ionizing radiation. Modulation of the AMPK, Akt and mTOR pathways |
| Q36466614 | Resveratrol inhibits the proliferation of neural progenitor cells and hippocampal neurogenesis |
| Q48052882 | Reversible developmental stasis in response to nutrient availability in the Xenopus laevis central nervous system |
| Q36067769 | Reversible induction of translational isoforms of p53 in glucose deprivation. |
| Q24316273 | Ribavirin enhances interferon signaling via stimulation of mTOR and p53 activities |
| Q40246328 | Ribosomal stress couples the unfolded protein response to p53-dependent cell cycle arrest |
| Q33887047 | Risk of gastric cancer is associated with PRKAA1 gene polymorphisms in Koreans |
| Q38200018 | Role of AMP-activated protein kinase in cancer therapy |
| Q43848574 | Role of AMP-activated protein kinase in regulating hypoxic survival and proliferation of mesenchymal stem cells |
| Q36301101 | Role of AMPK in UVB-induced DNA damage repair and growth control |
| Q37716390 | Role of AMPK throughout meiotic maturation in the mouse oocyte: Evidence for promotion of polar body formation and suppression of premature activation |
| Q37690890 | Role of Autophagy and Apoptosis in Non-Small-Cell Lung Cancer |
| Q46252237 | Role of metformin on base excision repair pathway in p53 wild-type H2009 and HepG2 cancer cells |
| Q93148944 | Role of p53 Family Proteins in Metformin Anti-Cancer Activities |
| Q46184680 | Role of p53 in mitochondrial biogenesis and apoptosis in skeletal muscle. |
| Q36780731 | Role of stress-activated OCT4A in the cell fate decisions of embryonal carcinoma cells treated with etoposide. |
| Q27000504 | Rottlerin and cancer: novel evidence and mechanisms |
| Q37418460 | S-adenosylmethionine limitation induces p38 mitogen-activated protein kinase and triggers cell cycle arrest in G1. |
| Q52368871 | SESN2 negatively regulates cell proliferation and casein synthesis by inhibition the amino acid-mediated mTORC1 pathway in cow mammary epithelial cells. |
| Q24316768 | SIK1 couples LKB1 to p53-dependent anoikis and suppresses metastasis |
| Q37815730 | SIRT1 and AMPK in regulating mammalian senescence: a critical review and a working model |
| Q24301693 | SIRT1 promotes proliferation and prevents senescence through targeting LKB1 in primary porcine aortic endothelial cells |
| Q36563406 | SIRT6 deacetylates PKM2 to suppress its nuclear localization and oncogenic functions |
| Q94671664 | SIRT7 activates p53 by enhancing PCAF-mediated MDM2 degradation to arrest the cell cycle |
| Q38298547 | Screening methods for AMP-activated protein kinase modulators: a patent review |
| Q30728294 | Selective Vulnerability of Cancer Cells by Inhibition of Ca(2+) Transfer from Endoplasmic Reticulum to Mitochondria |
| Q37614869 | Senescence-inducing stress promotes proteolysis of phosphoglycerate mutase via ubiquitin ligase Mdm2. |
| Q37000179 | Sepsis and AMPK Activation by AICAR Differentially Regulate FoxO-1, -3 and -4 mRNA in Striated Muscle |
| Q54119411 | Ser-486/491 phosphorylation and inhibition of AMPKα activity is positively associated with Gleason score, metastasis, and castration-resistance in prostate cancer: A retrospective clinical study. |
| Q39225768 | Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells. |
| Q35832028 | Serum withdrawal up-regulates human SIRT1 gene expression in a p53-dependent manner. |
| Q36638236 | Sestrin2 is induced by glucose starvation via the unfolded protein response and protects cells from non-canonical necroptotic cell death |
| Q34171596 | Sestrin2 modulates AMPK subunit expression and its response to ionizing radiation in breast cancer cells |
| Q90225264 | Sestrins as a Therapeutic Bridge between ROS and Autophagy in Cancer |
| Q38214338 | Sex and gender influences on pharmacological response: an overview |
| Q35232589 | Siah1/SIP regulates p27(kip1) stability and cell migration under metabolic stress. |
| Q28588964 | Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation |
| Q90589491 | Signaling networks in immunometabolism |
| Q46970612 | Similar mitochondrial signaling responses to a single bout of continuous or small-sided-games-based exercise in sedentary men. |
| Q34028698 | Sirt3 protects in vitro-fertilized mouse preimplantation embryos against oxidative stress-induced p53-mediated developmental arrest |
| Q35224775 | Small molecule adenosine 5'-monophosphate activated protein kinase (AMPK) modulators and human diseases |
| Q27339789 | Sodium tanshinone IIA silate inhibits high glucose-induced vascular smooth muscle cell proliferation and migration through activation of AMP-activated protein kinase |
| Q36266670 | Sphingolipid-based drugs selectively kill cancer cells by down-regulating nutrient transporter proteins |
| Q37002476 | Springing into Action: Reg2 Negatively Regulates Snf1 Protein Kinase and Facilitates Recovery from Prolonged Glucose Starvation in Saccharomyces cerevisiae |
| Q37692294 | Sprint-interval but not continuous exercise increases PGC-1α protein content and p53 phosphorylation in nuclear fractions of human skeletal muscle |
| Q46118117 | Stabilization and activation of p53 downregulates mTOR signaling through AMPK in mantle cell lymphoma |
| Q34501203 | Starvation-induced activation of ATM/Chk2/p53 signaling sensitizes cancer cells to cisplatin |
| Q35008883 | Stimulation of mTORC1 with L-leucine rescues defects associated with Roberts syndrome. |
| Q36623669 | Stress and mTORture signaling |
| Q37780207 | Stress-responsive sestrins link p53 with redox regulation and mammalian target of rapamycin signaling |
| Q36643052 | Sugar and fat - that's where it's at: metabolic changes in tumors |
| Q37802748 | Sugar-free approaches to cancer cell killing |
| Q35110805 | Suppression of AMPK activation via S485 phosphorylation by IGF-I during hyperglycemia is mediated by AKT activation in vascular smooth muscle cells |
| Q38787620 | Suppression of B-Raf(V600E) cancers by MAPK hyper-activation |
| Q37718416 | Suppression of gain-of-function mutant p53 with metabolic inhibitors reduces tumor growth in vivo |
| Q21136155 | Suppression of lung tumorigenesis by leucine zipper/EF hand-containing transmembrane-1 |
| Q35116609 | Suppression of the HSF1-mediated proteotoxic stress response by the metabolic stress sensor AMPK |
| Q45863481 | Synergistic effects of eukaryotic coexpression plasmid carrying LKB1 and FUS1 genes on lung cancer in vitro and in vivo |
| Q39436606 | Synthesis of cytochrome C oxidase 2: a p53-dependent metabolic regulator that promotes respiratory function and protects glioma and colon cancer cells from hypoxia-induced cell death |
| Q47778719 | Synthetic lethal metabolic targeting of cellular senescence in cancer therapy. |
| Q37568665 | Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth |
| Q26766427 | T Cells and Cancer: How Metabolism Shapes Immunity |
| Q36956949 | T cell proliferation and adaptive immune responses are critically regulated by protein phosphatase 4. |
| Q39200157 | TAK1 activates AMPK-dependent cell death pathway in hydrogen peroxide-treated cardiomyocytes, inhibited by heat shock protein-70. |
| Q41872025 | TIGAR, TIGAR, burning bright. |
| Q49714600 | TP53 is required for BECN1- and ATG5-dependent cell death induced by sphingosine kinase 1 inhibition |
| Q91701493 | Taking up the reins of power: metabolic functions of p53 |
| Q35781311 | Targeting AMPK for cancer prevention and treatment |
| Q36949580 | Targeting AMPK signaling in combating ovarian cancers: opportunities and challenges. |
| Q47130471 | Targeting PP2A activates AMPK signaling to inhibit colorectal cancer cells |
| Q64976486 | Targeting autophagy using metallic nanoparticles: a promising strategy for cancer treatment. |
| Q41339882 | Targeting metabolism and AMP-activated kinase with metformin to sensitize non-small cell lung cancer (NSCLC) to cytotoxic therapy: translational biology and rationale for current clinical trials |
| Q38016107 | Targeting metabolism for cancer treatment and prevention: metformin, an old drug with multi-faceted effects |
| Q36897348 | Targeting mitochondria in the treatment of human cancer: a coordinated attack against cancer cell energy metabolism and signalling |
| Q38995015 | Targeting of AMP-activated protein kinase: prospects for computer-aided drug design |
| Q35988679 | Targeting of short TRPM8 isoforms induces 4TM-TRPM8-dependent apoptosis in prostate cancer cells. |
| Q38323902 | Targeting the 5'-AMP-activated protein kinase and related metabolic pathways for the treatment of prostate cancer |
| Q37011502 | Targeting the AMP-Activated Protein Kinase for Cancer Prevention and Therapy |
| Q37506032 | Targeting the LKB1 tumor suppressor |
| Q24616273 | The AMPK signalling pathway coordinates cell growth, autophagy and metabolism |
| Q35754698 | The AMPK stress response pathway mediates anoikis resistance through inhibition of mTOR and suppression of protein synthesis |
| Q95642016 | The Anti-Breast Cancer Effect and Mechanism of Glimepiride-Metformin Adduct |
| Q34590433 | The Caenorhabditis elegans AMP-activated protein kinase AAK-2 is phosphorylated by LKB1 and is required for resistance to oxidative stress and for normal motility and foraging behavior |
| Q42323049 | The Evolution of TP53 Mutations: From Loss-of-Function to Separation-of-Function Mutants |
| Q92857841 | The Human G Protein-Coupled ATP Receptor P2Y11 Is Associated With IL-10 Driven Macrophage Differentiation |
| Q41687394 | The IGF-1R/AKT pathway determines cell fate in response to p53. |
| Q37274443 | The Krebs cycle meets the cell cycle: mitochondria and the G1-S transition |
| Q29617506 | The LKB1-AMPK pathway: metabolism and growth control in tumour suppression |
| Q40163084 | The MDM2 ubiquitination signal in the DNA-binding domain of p53 forms a docking site for calcium calmodulin kinase superfamily members |
| Q34047799 | The NADPH oxidases NOX4 and DUOX2 regulate cell cycle entry via a p53-dependent pathway |
| Q36430168 | The P53 pathway: what questions remain to be explored? |
| Q38896065 | The Paradox of p53: What, How, and Why? |
| Q37539373 | The Redox Status of Cancer Cells Supports Mechanisms behind the Warburg Effect |
| Q35103161 | The Ribosomal Protein-Mdm2-p53 Pathway and Energy Metabolism: Bridging the Gap between Feast and Famine |
| Q27936856 | The Snf1 kinase and proteasome-associated Rad23 regulate UV-responsive gene expression |
| Q99708992 | The Undervalued Avenue to Reinstate Tumor Suppressor Functionality of the p53 Protein Family for Improved Cancer Therapy-Drug Repurposing |
| Q26770007 | The Warburg effect and drug resistance |
| Q36291117 | The activation of G protein-coupled receptor 30 (GPR30) inhibits proliferation of estrogen receptor-negative breast cancer cells in vitro and in vivo |
| Q39709119 | The apical (hPepT1) and basolateral peptide transport systems of Caco-2 cells are regulated by AMP-activated protein kinase |
| Q38056782 | The cellular decision between apoptosis and autophagy |
| Q38802318 | The codon 72 polymorphism of p53 influences cell fate following nutrient deprivation |
| Q34143940 | The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes |
| Q34669361 | The complexities of obesity and diabetes with the development and progression of pancreatic cancer |
| Q39278240 | The dark face of AMPK as an essential tumor promoter |
| Q37115437 | The dark side of a tumor suppressor: anti-apoptotic p53. |
| Q30984546 | The diverse roles of adiponectin in non-small-cell lung cancer: current data and future perspectives |
| Q28085138 | The effect of environmental chemicals on the tumor microenvironment |
| Q36453693 | The effect of metformin and thiazolidinedione use on lung cancer in diabetics |
| Q36221605 | The effects of a novel aliphatic-chain hydroxamate derivative WMJ-S-001 in HCT116 colorectal cancer cell death |
| Q29622875 | The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis |
| Q51004205 | The energy sensing LKB1-AMPKα1 pathway regulates IGF1 secretion and consequent activation of the IGF1R-PKB pathway in primary hepatocytes. |
| Q37791418 | The engine driving the ship: metabolic steering of cell proliferation and death. |
| Q40777614 | The family that eats together stays together: new p53 family transcriptional targets in autophagy |
| Q39947245 | The fine tuning of metabolism, autophagy and differentiation during in vitro myogenesis. |
| Q24645732 | The first 30 years of p53: growing ever more complex |
| Q27863460 | The genetics of the p53 pathway, apoptosis and cancer therapy |
| Q35215557 | The glycolytic shift in fumarate-hydratase-deficient kidney cancer lowers AMPK levels, increases anabolic propensities and lowers cellular iron levels |
| Q46253613 | The guardian of the genome p53 regulates exercise-induced mitochondrial plasticity beyond organelle biogenesis. |
| Q34411887 | The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism |
| Q38109711 | The impact of age on oncogenic potential: tumor-initiating cells and the brain microenvironment |
| Q34095570 | The impact of type 2 diabetes and antidiabetic drugs on cancer cell growth |
| Q34041919 | The increase of cell-membranous phosphatidylcholines containing polyunsaturated fatty acid residues induces phosphorylation of p53 through activation of ATR. |
| Q39858276 | The isatin-Schiff base copper(II) complex Cu(isaepy)2 acts as delocalized lipophilic cation, yields widespread mitochondrial oxidative damage and induces AMP-activated protein kinase-dependent apoptosis |
| Q37773430 | The metabolic life and times of a T-cell |
| Q36753310 | The mitochondrial transport protein SLC25A43 affects drug efficacy and drug-induced cell cycle arrest in breast cancer cell lines |
| Q47737436 | The mitochondrion: a central architect of copper homeostasis. |
| Q28580062 | The oncogene c-Myc coordinates regulation of metabolic networks to enable rapid cell cycle entry |
| Q38559901 | The opposing actions of target of rapamycin and AMP-activated protein kinase in cell growth control |
| Q58780971 | The p53/Adipose-Tissue/Cancer Nexus |
| Q90157375 | The paradox of metabolism in quiescent stem cells |
| Q36782275 | The pentacyclic triterpenoid, plectranthoic acid, a novel activator of AMPK induces apoptotic death in prostate cancer cells |
| Q43092036 | The phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2)-dependent Tup1 conversion (PIPTC) regulates metabolic reprogramming from glycolysis to gluconeogenesis |
| Q37317189 | The platelet isoform of phosphofructokinase contributes to metabolic reprogramming and maintains cell proliferation in clear cell renal cell carcinoma |
| Q36326369 | The presence of wild type p53 in hematological cancers improves the efficacy of combinational therapy targeting metabolism |
| Q44785984 | The prolyl isomerase Pin1 interacts with and downregulates the activity of AMPK leading to induction of tumorigenicity of hepatocarcinoma cells |
| Q37732831 | The regulation of energy metabolism and the IGF-1/mTOR pathways by the p53 protein |
| Q42098498 | The role of AMP-activated protein kinase in the functional effects of vascular endothelial growth factor-A and -B in human aortic endothelial cells. |
| Q37852162 | The role of LKB1 and AMPK in cellular responses to stress and damage |
| Q42174809 | The role of glucose metabolism and glucose-associated signalling in cancer. |
| Q93023448 | The role of glycolysis and mitochondrial respiration in the formation and functioning of endothelial tip cells during angiogenesis |
| Q38201044 | The role of mitochondria in the development and progression of lung cancer |
| Q38532744 | The role of mitochondrial disturbances in Alzheimer, Parkinson and Huntington diseases |
| Q37781688 | The role of p53 in cell metabolism |
| Q33814261 | The role of the DNA damage response in zebrafish and cellular models of Diamond Blackfan anemia. |
| Q27026481 | The role of the cilium in normal and abnormal cell cycles: emphasis on renal cystic pathologies |
| Q28079903 | The role of the p53 tumor suppressor in metabolism and diabetes |
| Q27027604 | The role of tumor suppressor p53 in the antioxidant defense and metabolism |
| Q38242060 | The roles of FoxOs in modulation of aging by calorie restriction |
| Q43211202 | The serine/threonine kinase LKB1 controls thymocyte survival through regulation of AMPK activation and Bcl-XL expression |
| Q91748821 | The strange case of AMPK and cancer: Dr Jekyll or Mr Hyde? † |
| Q38080278 | The tangled circuitry of metabolism and apoptosis |
| Q35017906 | The tumor suppressor protein p53 is required for neurite outgrowth and axon regeneration |
| Q30499819 | The zebrafish embryo as a dynamic model of anoxia tolerance |
| Q45374016 | Thiazolidinediones inhibit hepatocarcinogenesis in hepatitis B virus-transgenic mice by peroxisome proliferator-activated receptor gamma-independent regulation of nucleophosmin |
| Q40104707 | To Eat and to Be Eaten: Mutual Metabolic Adaptations of Immune Cells and Intracellular Bacterial Pathogens upon Infection |
| Q37670829 | To be, or not to be: functional dilemma of p53 metabolic regulation |
| Q42288158 | Toxicological effects of NCKU-21, a phenanthrene derivative, on cell growth and migration of A549 and CL1-5 human lung adenocarcinoma cells. |
| Q38225367 | Transcriptional regulation of the stress response by mTOR. |
| Q42758453 | Transcriptomic analysis reveals inhibition of androgen receptor activity by AMPK in prostate cancer cells |
| Q24338238 | Translational Upregulation of an Individual p21Cip1 Transcript Variant by GCN2 Regulates Cell Proliferation and Survival under Nutrient Stress |
| Q38259322 | Triple-negative breast cancer: investigating potential molecular therapeutic target |
| Q35785657 | Tumor TP53 expression status, body mass index and prognosis in colorectal cancer |
| Q36639286 | Tumor metabolism: new opportunities for cancer therapy |
| Q91272383 | Tumor necrosis factor induces rapid down-regulation of TXNIP in human T cells |
| Q37390879 | Tumor suppressors and cell metabolism: a recipe for cancer growth |
| Q37740336 | Tumor-associated mutant p53 promotes cancer cell survival upon glutamine deprivation through p21 induction. |
| Q37591937 | Tumour suppression by p53: a role for the DNA damage response? |
| Q27013594 | Two-way communication between the metabolic and cell cycle machineries: the molecular basis |
| Q38884723 | Tyr99 phosphorylation determines the regulatory milieu of tumor suppressor p73. |
| Q28474973 | Uncoupling of the LKB1-AMPKalpha energy sensor pathway by growth factors and oncogenic BRAF |
| Q47111189 | Updates from the TP53 universe |
| Q47588098 | Upregulation of the ALDOA/DNA-PK/p53 pathway by dietary restriction suppresses tumor growth. |
| Q36623657 | Upstream of the mammalian target of rapamycin: do all roads pass through mTOR? |
| Q37636467 | Ursolic Acid-Regulated Energy Metabolism-Reliever or Propeller of Ultraviolet-Induced Oxidative Stress and DNA Damage? |
| Q39038752 | Ursolic acid differentially modulates apoptosis in skin melanoma and retinal pigment epithelial cells exposed to UV-VIS broadband radiation |
| Q35466765 | Use of noninsulin anti diabetics for prevention and treatment of cancer- narrative review article |
| Q57054188 | Variation in genes coding for AMP-activated protein kinase (AMPK) and breast cancer risk in the European Prospective Investigation on Cancer (EPIC) |
| Q38164707 | Viruses as modulators of mitochondrial functions |
| Q42510090 | Vital staining with iodine solution in oral cancer: iodine infiltration, cell proliferation, and glucose transporter 1. |
| Q37156031 | Winter temperature and UV are tightly linked to genetic changes in the p53 tumor suppressor pathway in Eastern Asia |
| Q64272949 | mTOR Inhibitors in Advanced Biliary Tract Cancers |
| Q33348248 | mTOR and cancer: many loops in one pathway. |
| Q38034265 | mTOR, metabolism, and the regulation of T-cell differentiation and function |
| Q26864688 | mTOR-dependent cell survival mechanisms |
| Q24633662 | mTOR: from growth signal integration to cancer, diabetes and ageing |
| Q47262982 | miR-144/451 represses the LKB1/AMPK/mTOR pathway to promote red cell precursor survival during recovery from acute anemia |
| Q89907568 | miR-4999-5p Predicts Colorectal Cancer Survival Outcome and Reprograms Glucose Metabolism by Targeting PRKAA2 |
| Q42265677 | microRNA-135b expression silences Ppm1e to provoke AMPK activation and inhibit osteoblastoma cell proliferation |
| Q34357915 | microRNAs and cancer metabolism reprogramming: the paradigm of metformin |
| Q39610419 | p-HPEA-EDA, a phenolic compound of virgin olive oil, activates AMP-activated protein kinase to inhibit carcinogenesis |
| Q37379089 | p21 expression in colon cancer and modifying effects of patient age and body mass index on prognosis |
| Q92422648 | p21cip1/waf1 Coordinate Autophagy, Proliferation and Apoptosis in Response to Metabolic Stress |
| Q57161298 | p53 Functions in Adipose Tissue Metabolism and Homeostasis |
| Q34670488 | p53 Pro72Arg polymorphism and prostate cancer in men of African descent |
| Q90726562 | p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression |
| Q33936026 | p53 and ARF: unexpected players in autophagy |
| Q29617084 | p53 and metabolism |
| Q55002919 | p53 and metabolism: from mechanism to therapeutics. |
| Q36739079 | p53 and metabolism: old player in a new game |
| Q37407735 | p53 and regulation of tumor metabolism |
| Q51761242 | p53 as a Dichotomous Regulator of Liver Disease: The Dose Makes the Medicine. |
| Q79306638 | p53 downstream target genes and tumor suppression: a classical view in evolution |
| Q29619939 | p53 in health and disease |
| Q38268953 | p53 in liver pathologies-taking the good with the bad. |
| Q38540071 | p53 in survival, death and metabolic health: a lifeguard with a licence to kill |
| Q33586467 | p53 is an important factor for the radiosensitization effect of 2-deoxy-D-glucose |
| Q41942949 | p53 is necessary for the adaptive changes in cellular milieu subsequent to an acute bout of endurance exercise. |
| Q37698274 | p53 regulation of the IGF-1/AKT/mTOR pathways and the endosomal compartment |
| Q92276564 | p53 sensitizes chemoresistant non-small cell lung cancer via elevation of reactive oxygen species and suppression of EGFR/PI3K/AKT signaling |
| Q42750029 | p53, DNA damage, and NAD+ homeostasis |
| Q36724268 | p53-Dependent regulation of metabolic function through transcriptional activation of pantothenate kinase-1 gene |
| Q91787476 | p53-mediated control of aspartate-asparagine homeostasis dictates LKB1 activity and modulates cell survival |
| Q37315159 | p53/CEP-1 increases or decreases lifespan, depending on level of mitochondrial bioenergetic stress. |
| Q34127834 | p53: exercise capacity and metabolism |
| Q30417298 | α-SNAP inhibits AMPK signaling to reduce mitochondrial biogenesis and dephosphorylates Thr172 in AMPKα in vitro |
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