| scholarly article | Q13442814 |
| P50 | author | Stefania Orecchioni | Q56992583 |
| Francesca Reggiani | Q57159678 | ||
| Martin Villalba | Q57425448 | ||
| Nerea Allende-Vega | Q64788606 | ||
| Francesco Bertolini | Q56850281 | ||
| P2093 | author name string | Jean-François Rossi | |
| Yosr Hicheri | |||
| Guillaume Cartron | |||
| Rodrigue Rossignol | |||
| Giovanna Talarico | |||
| Ewelina Krzywinska | |||
| Nuria Lopez-Royuela | |||
| P2860 | cites work | Role of AMP-activated protein kinase in mechanism of metformin action | Q22241898 |
| Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species | Q24305112 | ||
| Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function | Q24306243 | ||
| Glucose catabolism in cancer cells. The type II hexokinase promoter contains functionally active response elements for the tumor suppressor p53 | Q24308421 | ||
| MdmX is a substrate for the deubiquitinating enzyme USP2a | Q24336863 | ||
| Role of dichloroacetate in the treatment of genetic mitochondrial diseases | Q24630740 | ||
| p53 gene mutation in B-cell chronic lymphocytic leukemia is associated with drug resistance and is independent of MDR1/MDR3 gene expression | Q27853401 | ||
| p53 regulates mitochondrial respiration | Q28242400 | ||
| Mitochondrial activation by inhibition of PDKII suppresses HIF1a signaling and angiogenesis in cancer | Q28267156 | ||
| Metabolic modulation of glioblastoma with dichloroacetate | Q28282255 | ||
| A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth | Q28283339 | ||
| p53 mutations in human cancers | Q28302973 | ||
| Chemical metabolic inhibitors for the treatment of blood-borne cancers | Q28822335 | ||
| Blinded by the Light: The Growing Complexity of p53 | Q29547590 | ||
| On respiratory impairment in cancer cells | Q29617276 | ||
| AMP-activated protein kinase induces a p53-dependent metabolic checkpoint | Q29618123 | ||
| p53 mutation is associated with progression in follicular lymphomas | Q70482896 | ||
| The antioxidant function of the p53 tumor suppressor | Q29619231 | ||
| Sodium dichloroacetate exhibits anti-leukemic activity in B-chronic lymphocytic leukemia (B-CLL) and synergizes with the p53 activator Nutlin-3. | Q34100963 | ||
| The NF-κB member p65 controls glutamine metabolism through miR-23a. | Q34277479 | ||
| Functional inactivation of endogenous MDM2 and CHIP by HSP90 causes aberrant stabilization of mutant p53 in human cancer cells | Q34989395 | ||
| p53 mutant breast cancer patients expressing p53γ have as good a prognosis as wild-type p53 breast cancer patients. | Q35029530 | ||
| Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate. | Q35118915 | ||
| The anti-leukemic activity of sodium dichloroacetate in p53mutated/null cells is mediated by a p53-independent ILF3/p21 pathway | Q35273665 | ||
| Mutant p53: one name, many proteins | Q36070574 | ||
| The warburg effect in leukemia-stroma cocultures is mediated by mitochondrial uncoupling associated with uncoupling protein 2 activation | Q36925362 | ||
| ROS and p53: a versatile partnership | Q37085000 | ||
| Evaluation of long-term treatment of children with congenital lactic acidosis with dichloroacetate | Q37182886 | ||
| Tumor suppressors and cell metabolism: a recipe for cancer growth | Q37390879 | ||
| p53 regulation of metabolic pathways | Q37746471 | ||
| The Role of p53 in Metabolic Regulation | Q37903700 | ||
| From tumor cell metabolism to tumor immune escape | Q38008488 | ||
| p53 mutations in cancer | Q38069463 | ||
| Mutant p53 in cancer: new functions and therapeutic opportunities | Q38197826 | ||
| Hypoxia triggers AMPK activation through reactive oxygen species-mediated activation of calcium release-activated calcium channels | Q38284815 | ||
| Oxidative phosphorylation induces de novo expression of the MHC class I in tumor cells through the ERK5 pathway. | Q39664735 | ||
| Sodium dichloroacetate selectively targets cells with defects in the mitochondrial ETC. | Q39695465 | ||
| Dichloroacetate metabolically targeted therapy defeats cytotoxicity of standard anticancer drugs | Q39700283 | ||
| Therapeutic effect of lenalidomide in a novel xenograft mouse model of human blastic NK cell lymphoma/blastic plasmacytoid dendritic cell neoplasm. | Q39715692 | ||
| ERK5 knockdown generates mouse leukemia cells with low MHC class I levels that activate NK cells and block tumorigenesis. | Q39876512 | ||
| Polygonatum cyrtonema lectin induces apoptosis and autophagy in human melanoma A375 cells through a mitochondria-mediated ROS-p38-p53 pathway | Q39916629 | ||
| Human acute leukemia cells injected in NOD/LtSz-scid/IL-2Rgamma null mice generate a faster and more efficient disease compared to other NOD/scid-related strains. | Q39952676 | ||
| The regulation of AMPK beta1, TSC2, and PTEN expression by p53: stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways | Q40149396 | ||
| Altered glucose metabolism in childhood pre-B acute lymphoblastic leukaemia | Q40220152 | ||
| Human leukemias with mutated FLT3 kinase are synergistically sensitive to FLT3 and Hsp90 inhibitors: the key role of the STAT5 signal transduction pathway | Q40395107 | ||
| Gain-of-function mutant p53 promotes cell growth and cancer cell metabolism via inhibition of AMPK activation. | Q41046980 | ||
| The clinical significance of mutations of the P53 tumour suppressor gene in haematological malignancies | Q41613728 | ||
| Non-Hodgkin's Lymphoma Reversal with Dichloroacetate | Q41893494 | ||
| Medullary thyroid carcinoma relapse reversed with dichloroacetate: A case report | Q42026891 | ||
| The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation | Q42953330 | ||
| Severe encephalopathy and polyneuropathy induced by dichloroacetate. | Q42969875 | ||
| Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translation. | Q43228472 | ||
| Monoallelic and biallelic inactivation of TP53 gene in chronic lymphocytic leukemia: selection, impact on survival, and response to DNA damage | Q43256441 | ||
| Rheb regulates mitophagy induced by mitochondrial energetic status | Q44267253 | ||
| FLT3 expressing leukemias are selectively sensitive to inhibitors of the molecular chaperone heat shock protein 90 through destabilization of signal transduction-associated kinases. | Q44615054 | ||
| Clinical significance of p53 mutations in relapsed T-cell acute lymphoblastic leukemia. | Q46121671 | ||
| Activation of AMP-activated protein kinase induces p53-dependent apoptotic cell death in response to energetic stress | Q46868426 | ||
| Targeting Hsp90 by 17-AAG in leukemia cells: mechanisms for synergistic and antagonistic drug combinations with arsenic trioxide and Ara-C. | Q46947497 | ||
| Extracellular-signal-regulated kinase 5 modulates the antioxidant response by transcriptionally controlling Sirtuin 1 expression in leukemic cells. | Q54348750 | ||
| P433 | issue | 22 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 19228-19245 | |
| P577 | publication date | 2015-08-01 | |
| P1433 | published in | Oncotarget | Q1573155 |
| P1476 | title | The presence of wild type p53 in hematological cancers improves the efficacy of combinational therapy targeting metabolism | |
| P478 | volume | 6 |
| Q35995708 | CD45 Isoform Profile Identifies Natural Killer (NK) Subsets with Differential Activity. |
| Q49303366 | Changes in metabolism affect expression of ABC transporters through ERK5 and depending on p53 status |
| Q58107754 | Dichloroacetate ameliorates cardiac dysfunction caused by ischemic insults through AMPK signal pathway- not only shifts metabolism |
| Q36538773 | Human Leukemic Cells performing Oxidative Phosphorylation (OXPHOS) Generate an Antioxidant Response Independently of Reactive Oxygen species (ROS) Production |
| Q41079477 | Identification of Anti-tumor Cells Carrying Natural Killer (NK) Cell Antigens in Patients With Hematological Cancers |
| Q64078232 | Metabolic stress controls mutant p53 R248Q stability in acute myeloid leukemia cells |
| Q55074297 | Mitochondrial Complex I activity signals antioxidant response through ERK5. |
| Q33752927 | Mitochondrial targeting by dichloroacetate improves outcome following hemorrhagic shock |
| Q92082570 | Mutations in the ND2 Subunit of Mitochondrial Complex I Are Sufficient to Confer Increased Tumorigenic and Metastatic Potential to Cancer Cells |
| Q40600575 | Newcastle disease virus, rituximab, and doxorubicin combination as anti-hematological malignancy therapy |
| Q41632623 | The PDK1 Inhibitor Dichloroacetate Controls Cholesterol Homeostasis Through the ERK5/MEF2 Pathway |
| Q89655653 | Venetoclax response is enhanced by selective inhibitor of nuclear export compounds in hematologic malignancies |
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