DAPK-1 binding to a linear peptide motif in MAP1B stimulates autophagy and membrane blebbing. (scientific article)

A death-associated protein kinase (DAPK)-interacting protein, DIP-1, is an E3 ubiquitin ligase that promotes tumor necrosis factor-induced apoptosis and regulates the cellular levels of DAPK

Q24645599

Antisense Depletion of Death-associated Protein Kinase Promotes Apoptosis

Q24646487

Identification of a new form of death-associated protein kinase that promotes cell survival

Q24646510

ELM server: A new resource for investigating short functional sites in modular eukaryotic proteins

Q24672414

DAP-kinase induces apoptosis by suppressing integrin activity and disrupting matrix survival signals

Q24672929

DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death

Q24673427

Systematic discovery of new recognition peptides mediating protein interaction networks

Q24817114

Differential binding regulation of microtubule-associated proteins MAP1A, MAP1B, and MAP2 by tubulin polyglutamylation

Q28208458

Role of MAP1B in axonal retrograde transport of mitochondria

Q28507394

Microtubules facilitate autophagosome formation and fusion of autophagosomes with endosomes

Q28572782

The mouse kinome: discovery and comparative genomics of all mouse protein kinases

Q28588919

Chk1 and Chk2 kinases in checkpoint control and cancer

Q29617706

3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

Q29617843

AMP-activated protein kinase induces a p53-dependent metabolic checkpoint

Q29618123

The N-terminal interferon-binding domain (IBiD) homology domain of p300 binds to peptides with homology to the p53 transactivation domain

Q30839057

A functional genetic screen identifies regions at the C-terminal tail and death-domain of death-associated protein kinase that are critical for its proapoptotic activity

Q30839612

The Proline Repeat Domain of p53 Binds Directly to the Transcriptional Coactivator p300 and Allosterically Controls DNA-Dependent Acetylation of p53

Q31023819

Expansion of protein interaction maps by phage peptide display using MDM2 as a prototypical conformationally flexible target protein

Q33198816

The C-terminal regulatory domain of p53 contains a functional docking site for cyclin A.

Q33908542

Chk2-deficient mice exhibit radioresistance and defective p53-mediated transcription

Q34149479

ATM--a key determinant of multiple cellular responses to irradiation

Q34476600

Peptides mediating interaction networks: new leads at last

Q34564810

Microtubule Assembly in the Absence of Added Nucleotides

Q35098486

Microtubules and growth cone function.

Q35575888

The MAP1 family of microtubule-associated proteins

Q35605963

Autophagy as a cell death and tumor suppressor mechanism

Q35743138

New roles for the LKB1-->AMPK pathway.

Q36076064

Kinomics: methods for deciphering the kinome

Q36079218

Downregulation of death-associated protein kinase 1 (DAPK1) in chronic lymphocytic leukemia

Q36287377

Identification of a dominant negative functional domain on DAPK-1 that degrades DAPK-1 protein and stimulates TNFR-1-mediated apoptosis

Q38304316

Glycogen synthase kinase-3beta phosphorylation of MAP1B at Ser1260 and Thr1265 is spatially restricted to growing axons.

Q38330149

Evidence for the role of MAP1B in axon formation

Q39092885

A plant triterpenoid, avicin D, induces autophagy by activation of AMP-activated protein kinase

Q40095615

The MDM2 ubiquitination signal in the DNA-binding domain of p53 forms a docking site for calcium calmodulin kinase superfamily members

Q40163084

Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy

Q40250473

The tumor suppressor DAP kinase is a target of RSK-mediated survival signaling

Q40364004

MAP1B is required for Netrin 1 signaling in neuronal migration and axonal guidance.

Q40547702

DAP kinase activates a p19ARF/p53-mediated apoptotic checkpoint to suppress oncogenic transformation

Q40833586

Novel phosphorylation sites of human tumour suppressor protein p53 at Ser20 and Thr18 that disrupt the binding of mdm2 (mouse double minute 2) protein are modified in human cancers

Q40938040

DAP-kinase is a Ca2+/calmodulin-dependent, cytoskeletal-associated protein kinase, with cell death-inducing functions that depend on its catalytic activity

Q41848995

Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A.

Q42439288

The conformationally flexible S9-S10 linker region in the core domain of p53 contains a novel MDM2 binding site whose mutation increases ubiquitination of p53 in vivo

Q43941701

Patterns and clusters within the PSM column in TiBS, 1992-2004.

Q43967014

Overexpression of full-length but not N-terminal truncated isoform of microtubule-associated protein (MAP) 1B accelerates apoptosis of cultured cortical neurons

Q44177141

Signal transduction. Unexpected mediators of protein phosphorylation

Q45190367

The MAP kinase pathway is upstream of the activation of GSK3beta that enables it to phosphorylate MAP1B and contributes to the stimulation of axon growth.

Q45287460

MAP5: a novel brain microtubule-associated protein under strong developmental regulation

Q48266757

A germ line mutation in the death domain of DAPK-1 inactivates ERK-induced apoptosis.

Q52576454

P433

issue

P407

language of work or name

English

Q1860

P921