Activation of AMP-activated protein kinase inhibits the proliferation of human endothelial cells

scientific article

Activation of AMP-activated protein kinase inhibits the proliferation of human endothelial cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1124/JPET.112.194712
P932PMC publication ID3422516
P698PubMed publication ID22700432
P5875ResearchGate publication ID225375220

P2093author name stringWilliam Durante
Kelly J Peyton
Xiao-ming Liu
Yajie Yu
Benjamin Yates
P2860cites workRole of AMP-activated protein kinase in mechanism of metformin actionQ22241898
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AMP-activated kinase regulates cytoplasmic HuR.Q24537360
Metformin and reduced risk of cancer in diabetic patientsQ29616275
5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells?Q29618095
AMP-activated protein kinase induces a p53-dependent metabolic checkpointQ29618123
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Metformin associated with lower cancer mortality in type 2 diabetes: ZODIAC-16Q33602223
Activation of AMP-activated protein kinase by vascular endothelial growth factor mediates endothelial angiogenesis independently of nitric-oxide synthaseQ33796165
AMP-activated protein kinase activation as a strategy for protecting vascular endothelial functionQ33848040
Adenosine monophosphate-activated protein kinase induces cholesterol efflux from macrophage-derived foam cells and alleviates atherosclerosis in apolipoprotein E-deficient miceQ34236808
Activation of AMPK stimulates heme oxygenase-1 gene expression and human endothelial cell survivalQ34502017
Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.Q34506457
Antidiabetic therapies affect risk of pancreatic cancerQ34976430
Compound C inhibits vascular smooth muscle cell proliferation and migration in an AMP-activated protein kinase-independent fashionQ35122850
Adiponectin stimulates angiogenesis by promoting cross-talk between AMP-activated protein kinase and Akt signaling in endothelial cellsQ35218922
AMPKα2 deletion exacerbates neointima formation by upregulating Skp2 in vascular smooth muscle cellsQ35606335
Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase.Q36301403
Prevention of neonatal hyperbilirubinemia by tin protoporphyrin IX, a potent competitive inhibitor of heme oxidationQ36375988
Effect of metformin on the proliferation, migration, and MMP-2 and -9 expression of human umbilical vein endothelial cellsQ36383300
AMP-activated protein kinase--development of the energy sensor concept.Q36462587
Arginase promotes neointima formation in rat injured carotid arteriesQ37143923
AMP-activated protein kinase promotes the differentiation of endothelial progenitor cellsQ37332718
Activation of the AMPK-FOXO3 pathway reduces fatty acid-induced increase in intracellular reactive oxygen species by upregulating thioredoxinQ37360483
Hypochlorous acid-induced heme oxygenase-1 gene expression promotes human endothelial cell survivalQ37406247
Novel concepts in atherogenesis: angiogenesis and hypoxia in atherosclerosisQ37421663
AICAR preconditioning prevents postischemic leukocyte rolling and adhesion: role of K(ATP) channels and heme oxygenaseQ37445112
Activation of AMP-activated protein kinase suppresses oxidized low-density lipoprotein-induced macrophage proliferationQ37454154
Pharmacological AMP-kinase activators have compartment-specific effects on cell physiologyQ39473711
Role of the energy sensor adenosine monophosphate-activated protein kinase in the regulation of immature gonadotropin-releasing hormone neuron migrationQ39519862
Use of cells expressing gamma subunit variants to identify diverse mechanisms of AMPK activationQ39697365
AMPK-mediated phosphorylation of murine p27 at T197 promotes binding of 14-3-3 proteins and increases p27 stabilityQ39741365
Metformin inhibits cytokine-induced nuclear factor kappaB activation via AMP-activated protein kinase activation in vascular endothelial cellsQ40331177
Activators of the energy sensing kinase AMPK inhibit random cell movement and chemotaxis in U937 cellsQ40331830
5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinaseQ40370485
Cell cycle regulation via p53 phosphorylation by a 5'-AMP activated protein kinase activator, 5-aminoimidazole- 4-carboxamide-1-beta-D-ribofuranoside, in a human hepatocellular carcinoma cell lineQ40780866
The role of AMP-activated protein kinase in the functional effects of vascular endothelial growth factor-A and -B in human aortic endothelial cells.Q42098498
Roles of AMP-activated protein kinase in diabetes-induced retinal inflammationQ42725397
Hyperglycemia-induced apoptosis in human umbilical vein endothelial cells: inhibition by the AMP-activated protein kinase activationQ43833571
Heme oxygenase-1-derived carbon monoxide is an autocrine inhibitor of vascular smooth muscle cell growthQ44010394
Direct activation of AMP-activated protein kinase stimulates nitric-oxide synthesis in human aortic endothelial cellsQ44468960
AMP-activated protein kinase inhibits angiotensin II-stimulated vascular smooth muscle cell proliferationQ44985604
Inhibition of tumor necrosis factor alpha-stimulated monocyte adhesion to human aortic endothelial cells by AMP-activated protein kinaseQ46359191
Role of AMP-activated protein kinase in autophagy and proteasome functionQ46711950
Activation of the AMP-activated kinase by antidiabetes drug metformin stimulates nitric oxide synthesis in vivo by promoting the association of heat shock protein 90 and endothelial nitric oxide synthaseQ46917092
AMPKalpha1 regulates the antioxidant status of vascular endothelial cellsQ47801068
AMP-activated protein kinase (AMPK) signaling in endothelial cells is essential for angiogenesis in response to hypoxic stressQ47858200
AngiogenesisQ56689455
L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxationQ68431098
Inhibitors of nucleoside and nucleotide metabolismQ69458404
5'-AMP-activated protein kinase activation prevents postischemic leukocyte-endothelial cell adhesive interactionsQ80174822
AMP-activated protein kinase mediates erythropoietin-induced activation of endothelial nitric oxide synthaseQ82158092
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectendotheliumQ111140
P304page(s)827-834
P577publication date2012-06-13
P1433published inJournal of Pharmacology and Experimental TherapeuticsQ1500272
P1476titleActivation of AMP-activated protein kinase inhibits the proliferation of human endothelial cells
P478volume342

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cites work (P2860)
Q60915789A769662 Inhibits Insulin-Stimulated Akt Activation in Human Macrovascular Endothelial Cells Independent of AMP-Activated Protein Kinase
Q37175528AMP-activated protein kinase inhibits vascular smooth muscle cell proliferation and migration and vascular remodeling following injury
Q41819276AMPK knockdown in placental trophoblast cells results in altered morphology and function.
Q36359713Abnormal Glucose Metabolism in Alzheimer's Disease: Relation to Autophagy/Mitophagy and Therapeutic Approaches
Q57820854Angiogenesis: focusing on the effects of exercise in aging and cancer
Q64108633Canagliflozin Inhibits Human Endothelial Cell Proliferation and Tube Formation
Q34438700Colorectal and Prostate Cancer Risk in Diabetes: Metformin, an Actor behind the Scene
Q64376708Glutaminase-1 stimulates the proliferation, migration, and survival of human endothelial cells
Q37626018Heme oxygenase-1 counteracts contrast media-induced endothelial cell dysfunction
Q36835027Heme oxygenase-1-derived bilirubin counteracts HIV protease inhibitor-mediated endothelial cell dysfunction
Q28550674Metformin Induces Cell Cycle Arrest, Reduced Proliferation, Wound Healing Impairment In Vivo and Is Associated to Clinical Outcomes in Diabetic Foot Ulcer Patients
Q38662959Metformin Suppresses Proliferation and Viability of Rat Pheochromocytoma Cells
Q41999628Metformin impairs vascular endothelial recovery after stent placement in the setting of locally eluted mammalian target of rapamycin inhibitors via S6 kinase-dependent inhibition of cell proliferation
Q35027745Mitochondrial effectors of cellular senescence: beyond the free radical theory of aging
Q38829598New synthetic AICAR derivatives with enhanced AMPK and ACC activation
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Q47582689The branched-chain amino acid transaminase 1 sustains growth of antiestrogen-resistant and ERα-negative breast cancer
Q38152454p53 as an intervention target for cancer and aging

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