scholarly article | Q13442814 |
P50 | author | Ian P Salt | Q56876361 |
Timothy M Palmer | Q60975831 | ||
George Baillie | Q73827461 | ||
P2093 | author name string | Sarah J Mancini | |
Anastasiya Strembitska | |||
Jonathan M Gamwell | |||
P2860 | cites work | Phosphorylation of Janus kinase 1 (JAK1) by AMP-activated protein kinase (AMPK) links energy sensing to anti-inflammatory signaling. | Q51284981 |
AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965. | Q52309562 | ||
Effects of endurance training on activity and expression of AMP-activated protein kinase isoforms in rat muscles. | Q53668959 | ||
Canagliflozin inhibits interleukin-1β-stimulated cytokine and chemokine secretion in vascular endothelial cells by AMP-activated protein kinase-dependent and -independent mechanisms. | Q54119005 | ||
Vascular nitric oxide: Beyond eNOS | Q26779400 | ||
Structural basis of AMPK regulation by small molecule activators | Q27680957 | ||
The alpha1 and alpha2 isoforms of the AMP-activated protein kinase have similar activities in rat liver but exhibit differences in substrate specificity in vitro | Q28582647 | ||
AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice | Q28591122 | ||
The Akt kinase signals directly to endothelial nitric oxide synthase | Q28609847 | ||
Resveratrol inhibits inflammation and ameliorates insulin resistant endothelial dysfunction via regulation of AMP-activated protein kinase and sirtuin 1 activities | Q29347074 | ||
VEGF receptor signalling - in control of vascular function | Q29617256 | ||
Towards a knowledge-based Human Protein Atlas | Q29617987 | ||
Enhancement of insulin-mediated rat muscle glucose uptake and microvascular perfusion by 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside | Q30406455 | ||
Activation of AMP-activated protein kinase by vascular endothelial growth factor mediates endothelial angiogenesis independently of nitric-oxide synthase | Q33796165 | ||
Endothelial dysfunction in diabetes mellitus: molecular mechanisms and clinical implications | Q33901576 | ||
Activation of AMPK stimulates heme oxygenase-1 gene expression and human endothelial cell survival | Q34502017 | ||
Endothelial AMPK activation induces mitochondrial biogenesis and stress adaptation via eNOS-dependent mTORC1 signaling. | Q34518725 | ||
Elevated NF-κB activation is conserved in human myocytes cultured from obese type 2 diabetic patients and attenuated by AMP-activated protein kinase | Q35405108 | ||
Insulin, IGF-1 and longevity | Q35806709 | ||
Activation of AMP-activated protein kinase inhibits the proliferation of human endothelial cells | Q36174159 | ||
The AMPK Activator A769662 Blocks Voltage-Gated Sodium Channels: Discovery of a Novel Pharmacophore with Potential Utility for Analgesic Development | Q36258703 | ||
Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase. | Q36301403 | ||
Vasoprotective effects of resveratrol and SIRT1: attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations | Q36906571 | ||
Selective Insulin Resistance and the Development of Cardiovascular Diseases in Diabetes: The 2015 Edwin Bierman Award Lecture | Q36930826 | ||
Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells | Q37358571 | ||
Protein kinase C phosphorylates AMP-activated protein kinase α1 Ser487. | Q37488514 | ||
Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptor-associated kinase-4 phosphorylation | Q37582435 | ||
Metformin and salicylate synergistically activate liver AMPK, inhibit lipogenesis and improve insulin sensitivity | Q37583668 | ||
Lack of Adipocyte AMPK Exacerbates Insulin Resistance and Hepatic Steatosis through Brown and Beige Adipose Tissue Function. | Q37588539 | ||
Benzimidazole derivative small-molecule 991 enhances AMPK activity and glucose uptake induced by AICAR or contraction in skeletal muscle | Q37590986 | ||
Enhanced activation of cellular AMPK by dual-small molecule treatment: AICAR and A769662. | Q37629041 | ||
Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression. | Q37736322 | ||
Insulin and its analogues and their affinities for the IGF1 receptor. | Q37993843 | ||
Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome | Q38312576 | ||
A small molecule AMPK activator protects the heart against ischemia-reperfusion injury. | Q39100111 | ||
AKT/PKB Signaling: Navigating the Network | Q39255027 | ||
AMP-Activated Protein Kinase: An Ubiquitous Signaling Pathway With Key Roles in the Cardiovascular System. | Q39331294 | ||
AMPK as a Therapeutic Target for Treating Metabolic Diseases | Q39396294 | ||
Use of cells expressing gamma subunit variants to identify diverse mechanisms of AMPK activation | Q39697365 | ||
AMP-activated protein kinase activator A-769662 is an inhibitor of the Na(+)-K(+)-ATPase | Q39787435 | ||
A769662, a novel activator of AMP-activated protein kinase, inhibits non-proteolytic components of the 26S proteasome by an AMPK-independent mechanism | Q39966490 | ||
Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states | Q40250572 | ||
AMP-activated protein kinase is required for the lipid-lowering effect of metformin in insulin-resistant human HepG2 cells | Q40515180 | ||
Characterization of multiple signaling pathways of insulin in the regulation of vascular endothelial growth factor expression in vascular cells and angiogenesis | Q40643912 | ||
Insulin-stimulated activation of eNOS is independent of Ca2+ but requires phosphorylation by Akt at Ser(1179). | Q40799734 | ||
Bavachalcone-induced manganese superoxide dismutase expression through the AMP-activated protein kinase pathway in human endothelial cells | Q41232659 | ||
The role of AMP-activated protein kinase in the functional effects of vascular endothelial growth factor-A and -B in human aortic endothelial cells. | Q42098498 | ||
AMP-activated protein kinase (AMPK) activator A-769662 increases intracellular calcium and ATP release from astrocytes in an AMPK-independent manner | Q42505826 | ||
Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release. | Q42701436 | ||
AMP-activated protein kinase (AMPK) as a potential therapeutic target independent of PI3K/Akt signaling in prostate cancer. | Q43091920 | ||
Insulin-stimulated phosphorylation of endothelial nitric oxide synthase at serine-615 contributes to nitric oxide synthesis. | Q43238697 | ||
A-769662 activates AMPK beta1-containing complexes but induces glucose uptake through a PI3-kinase-dependent pathway in mouse skeletal muscle. | Q43298108 | ||
Hyperglycemia-induced apoptosis in human umbilical vein endothelial cells: inhibition by the AMP-activated protein kinase activation | Q43833571 | ||
Signaling pathways mediating phosphorylation and inactivation of glycogen synthase kinase-3β by the recombinant human δ-opioid receptor stably expressed in Chinese hamster ovary cells. | Q44349226 | ||
The AMP-Dependent Protein Kinase (AMPK) Activator A-769662 Causes Arterial Relaxation by Reducing Cytosolic Free Calcium Independently of an Increase in AMPK Phosphorylation | Q44405235 | ||
Direct activation of AMP-activated protein kinase stimulates nitric-oxide synthesis in human aortic endothelial cells | Q44468960 | ||
Synergistic activation of endothelial nitric-oxide synthase (eNOS) by HSP90 and Akt: calcium-independent eNOS activation involves formation of an HSP90-Akt-CaM-bound eNOS complex | Q44473651 | ||
Knockout of the alpha2 but not alpha1 5'-AMP-activated protein kinase isoform abolishes 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranosidebut not contraction-induced glucose uptake in skeletal muscle. | Q44628501 | ||
Acute renal ischemia rapidly activates the energy sensor AMPK but does not increase phosphorylation of eNOS-Ser1177. | Q46508470 | ||
Rosiglitazone stimulates nitric oxide synthesis in human aortic endothelial cells via AMP-activated protein kinase. | Q46731659 | ||
A-769662 potentiates the effect of other AMP-activated protein kinase activators on cardiac glucose uptake | Q46903583 | ||
Activation of the AMP-activated kinase by antidiabetes drug metformin stimulates nitric oxide synthesis in vivo by promoting the association of heat shock protein 90 and endothelial nitric oxide synthase | Q46917092 | ||
Obesity, type 2 diabetes, and impaired insulin-stimulated blood flow: role of skeletal muscle NO synthase and endothelin-1. | Q50333291 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 12 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 3886 | |
P577 | publication date | 2018-12-05 | |
P1433 | published in | International Journal of Molecular Sciences | Q3153277 |
P1476 | title | A769662 Inhibits Insulin-Stimulated Akt Activation in Human Macrovascular Endothelial Cells Independent of AMP-Activated Protein Kinase | |
P478 | volume | 19 |
Search more.