| scholarly article | Q13442814 |
| P50 | author | Richard A Cohen | Q73490259 |
| Ogyi Park | Q117248955 | ||
| Etienne Lefai | Q37382840 | ||
| Mengwei Zang | Q39942539 | ||
| Zhijun Luo | Q39942581 | ||
| P2093 | author name string | Yu Li | |
| Maria M Mihaylova | |||
| Reuben J Shaw | |||
| Bin Gao | |||
| Bin Zheng | |||
| Tony J Verbeuren | |||
| John Y-J Shyy | |||
| Michel Wierzbicki | |||
| Bingbing Jiang | |||
| Shanqin Xu | |||
| Xiuyun Hou | |||
| P2860 | cites work | LDL receptor but not apolipoprotein E deficiency increases diet-induced obesity and diabetes in mice | Q43819543 |
| A crystallized view of AMPK activation. | Q45936851 | ||
| Control of lipid metabolism by phosphorylation-dependent degradation of the SREBP family of transcription factors by SCF(Fbw7). | Q46626421 | ||
| The thromboxane A2 receptor antagonist S18886 prevents enhanced atherogenesis caused by diabetes mellitus | Q46783978 | ||
| Role of AMP-activated protein kinase in mechanism of metformin action | Q22241898 | ||
| ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs | Q24290776 | ||
| Hepatic PCSK9 expression is regulated by nutritional status via insulin and sterol regulatory element-binding protein 1c | Q24300790 | ||
| AMPK phosphorylation of raptor mediates a metabolic checkpoint | Q24329244 | ||
| Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells | Q24561820 | ||
| Overexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesis | Q24631468 | ||
| Resveratrol improves health and survival of mice on a high-calorie diet | Q27860950 | ||
| TSC2 mediates cellular energy response to control cell growth and survival | Q27860970 | ||
| SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation | Q28365331 | ||
| SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver | Q29547646 | ||
| Molecular mediators of hepatic steatosis and liver injury | Q29616709 | ||
| AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism | Q29617261 | ||
| Inhibition of SREBP by a Small Molecule, Betulin, Improves Hyperlipidemia and Insulin Resistance and Reduces Atherosclerotic Plaques | Q30054591 | ||
| AMP-activated protein kinase-deficient mice are resistant to the metabolic effects of resveratrol | Q33688533 | ||
| Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis | Q33734679 | ||
| Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP. | Q33953637 | ||
| Expression of fatty acid synthase in nonalcoholic fatty liver disease. | Q33962008 | ||
| Insulin resistance and atherosclerosis | Q34698887 | ||
| 5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments | Q35070875 | ||
| SREBPs: the crossroads of physiological and pathological lipid homeostasis | Q37091373 | ||
| From fatty streak to fatty liver: 33 years of joint publications in the JCI | Q37126009 | ||
| Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lep(ob)/Lep(ob) mice | Q38290693 | ||
| Short-term overexpression of a constitutively active form of AMP-activated protein kinase in the liver leads to mild hypoglycemia and fatty liver | Q38327316 | ||
| Use of cells expressing gamma subunit variants to identify diverse mechanisms of AMPK activation | Q39697365 | ||
| Role of NMDA receptor-dependent activation of SREBP1 in excitotoxic and ischemic neuronal injuries. | Q39766248 | ||
| AMP-activated protein kinase suppresses LXR-dependent sterol regulatory element-binding protein-1c transcription in rat hepatoma McA-RH7777 cells | Q39898336 | ||
| SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase | Q39981968 | ||
| Polyphenols stimulate AMP-activated protein kinase, lower lipids, and inhibit accelerated atherosclerosis in diabetic LDL receptor-deficient mice | Q40250591 | ||
| Sterol regulatory element-binding protein 1 is negatively modulated by PKA phosphorylation | Q40335539 | ||
| The role of AMP-activated protein kinase in the action of ethanol in the liver | Q40485116 | ||
| AMP-activated protein kinase is required for the lipid-lowering effect of metformin in insulin-resistant human HepG2 cells | Q40515180 | ||
| S17834, a new inhibitor of cell adhesion and atherosclerosis that targets nadph oxidase | Q43764578 | ||
| P433 | issue | 4 | |
| P921 | main subject | phosphorylation | Q242736 |
| insulin resistance | Q1053470 | ||
| atherosclerosis | Q12252367 | ||
| steatosis | Q1365091 | ||
| preproinsulin | Q7240673 | ||
| Protein kinase, AMP-activated, alpha 1 catalytic subunit | Q21498728 | ||
| Protein kinase, AMP-activated, alpha 2 catalytic subunit | Q21498733 | ||
| Sterol regulatory element binding transcription factor 1 | Q21988573 | ||
| P304 | page(s) | 376-388 | |
| P577 | publication date | 2011-04-01 | |
| P1433 | published in | Cell Metabolism | Q1254684 |
| P1476 | title | AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice | |
| P478 | volume | 13 |
| Q36611690 | (-)-Hydroxycitric acid reduced fat deposition via regulating lipid metabolism-related gene expression in broiler chickens |
| Q58766921 | -Limonene Enhances Differentiation and 2-Deoxy-D-Glucose Uptake in 3T3-L1 Preadipocytes by Activating the Akt Signaling Pathway |
| Q53795044 | 1-Deoxynojirimycin Alleviates Liver Injury and Improves Hepatic Glucose Metabolism in db/db Mice. |
| Q64093625 | 2, 3, 4′, 5-tetrahydroxystilbene-2-0-β-d Glycoside Attenuates Age- and Diet-Associated Non-Alcoholic Steatohepatitis and Atherosclerosis in LDL Receptor Knockout Mice and Its Possible Mechanisms |
| Q35289357 | 2-(3-Benzoylthioureido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid ameliorates metabolic disorders in high-fat diet-fed mice |
| Q43808610 | 3-Caffeoyl, 4-dihydrocaffeoylquinic acid from Salicornia herbacea attenuates high glucose-induced hepatic lipogenesis in human HepG2 cells through activation of the liver kinase B1 and silent information regulator T1/AMPK-dependent pathway |
| Q39341396 | 4'-Hydroxyflavanone suppresses activation of sterol regulatory element-binding proteins and de novo lipid synthesis |
| Q37608516 | 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) effect on glucose production, but not energy metabolism, is independent of hepatic AMPK in vivo |
| Q55512003 | A Controlled Fermented Samjunghwan Herbal Formula Ameliorates Non-alcoholic Hepatosteatosis in HepG2 Cells and OLETF Rats. |
| Q50931635 | A corn oil-based diet protects against combined ethanol and iron-induced liver injury in a mouse model of hemochromatosis. |
| Q64079567 | A functional interaction between Hippo-YAP signalling and SREBPs mediates hepatic steatosis in diabetic mice |
| Q38308630 | A nexus for cellular homeostasis: the interplay between metabolic and signal transduction pathways |
| Q36114705 | A novel inverse relationship between metformin-triggered AMPK-SIRT1 signaling and p53 protein abundance in high glucose-exposed HepG2 cells |
| Q38091672 | A pathway approach to investigate the function and regulation of SREBPs |
| Q37635755 | A redox-resistant sirtuin-1 mutant protects against hepatic metabolic and oxidant stress. |
| Q39124486 | A spatiotemporal hypothesis for the regulation, role, and targeting of AMPK in prostate cancer. |
| Q60915789 | A769662 Inhibits Insulin-Stimulated Akt Activation in Human Macrovascular Endothelial Cells Independent of AMP-Activated Protein Kinase |
| Q35560768 | AICAR-Induced Activation of AMPK Inhibits TSH/SREBP-2/HMGCR Pathway in Liver |
| Q58607160 | AMP-Activated Protein Kinase (AMPK)-Dependent Regulation of Renal Transport |
| Q51628179 | AMP-Activated Protein Kinase Alpha 2 Deletion Induces VSMC Phenotypic Switching and Reduces Features of Atherosclerotic Plaque Stability. |
| Q35908579 | AMP-Activated Protein Kinase Regulates Oxidative Metabolism in Caenorhabditis elegans through the NHR-49 and MDT-15 Transcriptional Regulators |
| Q38150151 | AMP-activated protein kinase (AMPK) beyond metabolism: a novel genomic stress sensor participating in the DNA damage response pathway |
| Q38214392 | AMP-activated protein kinase activators in diabetic ulcers: from animal studies to Phase II drugs under investigation |
| Q47912246 | AMP-activated protein kinase attenuates oxLDL uptake in macrophages through PP2A/NF-κB/LOX-1 pathway |
| Q46399403 | AMP-activated protein kinase α1 promotes atherogenesis by increasing monocyte-to-macrophage differentiation |
| Q38205759 | AMP-activated protein kinase: An emerging target for ginseng |
| Q38211516 | AMP-activated protein kinase: a key regulator of energy balance with many roles in human disease |
| Q26864424 | AMP-activated protein kinase: a target for drugs both ancient and modern |
| Q38026549 | AMP-activated protein kinase: an emerging drug target to regulate imbalances in lipid and carbohydrate metabolism to treat cardio-metabolic diseases |
| Q26865723 | AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function |
| Q38213662 | AMP-activated protein kinase: maintaining energy homeostasis at the cellular and whole-body levels |
| Q64883770 | AMPK Activation Mediated by Hinokitiol Inhibits Adipogenic Differentiation of Mesenchymal Stem Cells through Autophagy Flux. |
| Q38292405 | AMPK Activation by Metformin Suppresses Abnormal Extracellular Matrix Remodeling in Adipose Tissue and Ameliorates Insulin Resistance in Obesity |
| Q39754893 | AMPK Negatively Regulates Peripheral Myelination via Activation of c-Jun |
| Q42429527 | AMPK Phosphorylates Desnutrin/ATGL and Hormone-Sensitive Lipase To Regulate Lipolysis and Fatty Acid Oxidation within Adipose Tissue |
| Q49990861 | AMPK Re-Activation Suppresses Hepatic Steatosis but its Downregulation Does Not Promote Fatty Liver Development. |
| Q38998395 | AMPK Regulation of Cell Growth, Apoptosis, Autophagy, and Bioenergetics. |
| Q47109961 | AMPK activation caused by reduced liver lactate metabolism protects against hepatic steatosis in MCT1 haploinsufficient mice. |
| Q33689169 | AMPK activation--protean potential for boosting healthspan |
| Q98158781 | AMPK activator C24 inhibits hepatic lipogenesis and ameliorates dyslipidemia in HFHC diet-induced animal models |
| Q38998415 | AMPK as a Pro-longevity Target. |
| Q26829427 | AMPK as a potential anticancer target - friend or foe? |
| Q34871517 | AMPK at the nexus of energetics and aging. |
| Q36661543 | AMPK governs lineage specification through Tfeb-dependent regulation of lysosomes |
| Q38998405 | AMPK in Neurodegenerative Diseases |
| Q36532941 | AMPK is a negative regulator of the Warburg effect and suppresses tumor growth in vivo |
| Q38410304 | AMPK is involved in the differential neonatal performance of chicks hatching at different time |
| Q36302525 | AMPK modulatory activity of olive-tree leaves phenolic compounds: Bioassay-guided isolation on adipocyte model and in silico approach |
| Q92566859 | AMPK promotes induction of the tumor suppressor FLCN through activation of TFEB independently of mTOR |
| Q35793842 | AMPK-mediated energy homeostasis and associated metabolic effects on cancer cell response and resistance to cetuximab |
| Q39378752 | AMPK: Mechanisms of Cellular Energy Sensing and Restoration of Metabolic Balance |
| Q60927924 | AMPK: Regulation of Metabolic Dynamics in the Context of Autophagy |
| Q29615410 | AMPK: a nutrient and energy sensor that maintains energy homeostasis |
| Q45982416 | AMPK: guardian of metabolism and mitochondrial homeostasis. |
| Q54123251 | AMPKα inactivation destabilizes atherosclerotic plaque in streptozotocin-induced diabetic mice through AP-2α/miRNA-124 axis. |
| Q58604120 | AMPKα pathway involved in hepatic triglyceride metabolism disorder in diet-induced obesity mice following Infection |
| Q64945501 | Aberrant lipid metabolism as a therapeutic target in liver cancer. |
| Q34358489 | Abnormal unsaturated fatty acid metabolism in cystic fibrosis: biochemical mechanisms and clinical implications |
| Q34826374 | Acetic acid activates the AMP-activated protein kinase signaling pathway to regulate lipid metabolism in bovine hepatocytes |
| Q54980729 | Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical Models. |
| Q34795007 | Activation of sterol regulatory element binding protein and NLRP3 inflammasome in atherosclerotic lesion development in diabetic pigs |
| Q26745623 | Adenosine monophosphate-activated protein kinase in diabetic nephropathy |
| Q55619181 | Adiponectin Signaling Pathways in Liver Diseases. |
| Q58603859 | Adiponectin as a novel biomarker for liver fibrosis |
| Q28242180 | Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways |
| Q27690220 | Alcoholic liver disease: pathogenesis and new therapeutic targets |
| Q26861620 | Alcoholic liver disease: pathogenesis, management, and novel targets for therapy |
| Q92391926 | Alisol A attenuates high-fat-diet-induced obesity and metabolic disorders via the AMPK/ACC/SREBP-1c pathway |
| Q91658646 | Allomyrina dichotoma Larva Extract Ameliorates the Hepatic Insulin Resistance of High-Fat Diet-Induced Diabetic Mice |
| Q38798594 | Allyl isothiocyanate suppresses the proteolytic activation of sterol regulatory element-binding proteins and de novo fatty acid and cholesterol synthesis |
| Q93045588 | Alpha-ketoglutarate extends Drosophila lifespan by inhibiting mTOR and activating AMPK |
| Q35111400 | Alpha-lipoic acid reduces LDL-particle number and PCSK9 concentrations in high-fat fed obese Zucker rats |
| Q54311934 | Alpha-lipoic acid supplementation reduces mTORC1 signaling in skeletal muscle from high fat fed, obese Zucker rats. |
| Q51045917 | Ameliorative effects of pepsin-digested chicken liver hydrolysates on development of alcoholic fatty livers in mice. |
| Q37556607 | Analyzing the study of using acupuncture in delivery in the past ten years in china |
| Q26748844 | Androgen control of lipid metabolism in prostate cancer: novel insights and future applications |
| Q57110533 | Anti-Obesity Effects of Collagen Peptide Derived from Skate () Skin Through Regulation of Lipid Metabolism |
| Q42321603 | Anti-obesity effects of Boussingaulti gracilis Miers var. pseudobaselloides Bailey via activation of AMP-activated protein kinase in 3T3-L1 cells |
| Q95792983 | Antidiabetic and Antihyperlipidemic Effects of Clitocybe nuda on Glucose Transporter 4 and AMP-Activated Protein Kinase Phosphorylation in High-Fat-Fed Mice |
| Q90419651 | Aqueous Extract of Pepino (Solanum muriactum Ait) Leaves Ameliorate Lipid Accumulation and Oxidative Stress in Alcoholic Fatty Liver Disease |
| Q37021836 | Argininosuccinate synthetase regulates hepatic AMPK linking protein catabolism and ureagenesis to hepatic lipid metabolism |
| Q36251303 | Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach |
| Q53689698 | Astragaloside IV Inhibits Triglyceride Accumulation in Insulin-Resistant HepG2 Cells via AMPK-Induced SREBP-1c Phosphorylation. |
| Q53511517 | Astragaloside IV attenuates free fatty acid-induced ER stress and lipid accumulation in hepatocytes via AMPK activation. |
| Q61796504 | Attenuated Lymphatic Proliferation Ameliorates Diabetic Nephropathy and High-Fat Diet-Induced Renal Lipotoxicity |
| Q47392861 | Averrhoa carambola free phenolic extract ameliorates nonalcoholic hepatic steatosis by modulating mircoRNA-34a, mircoRNA-33 and AMPK pathways in leptin receptor-deficient db/db mice |
| Q36210910 | BNip3 regulates mitochondrial function and lipid metabolism in the liver. |
| Q90244721 | BabaoDan attenuates high-fat diet-induced non-alcoholic fatty liver disease via activation of AMPK signaling |
| Q37000389 | Bax Inhibitor-1 regulates hepatic lipid accumulation via ApoB secretion |
| Q36645454 | Berberine Ameliorates Hepatic Steatosis and Suppresses Liver and Adipose Tissue Inflammation in Mice with Diet-induced Obesity |
| Q42258667 | Berberine activates AMPK to suppress proteolytic processing, nuclear translocation and target DNA binding of SREBP-1c in 3T3-L1 adipocytes |
| Q47610112 | Berberine attenuates hepatic steatosis and enhances energy expenditure in mice by inducing autophagy and fibroblast growth factor 21. |
| Q64084960 | Berberine in Cardiovascular and Metabolic Diseases: From Mechanisms to Therapeutics |
| Q35935053 | Berberine-loaded solid lipid nanoparticles are concentrated in the liver and ameliorate hepatosteatosis in db/db mice |
| Q64091161 | Beta-Aminoisobutyric Acid as a Novel Regulator of Carbohydrate and Lipid Metabolism |
| Q55060254 | Betaine alleviates hepatic lipid accumulation via enhancing hepatic lipid export and fatty acid oxidation in rats fed with a high-fat diet. |
| Q55016760 | Betaine in Inflammation: Mechanistic Aspects and Applications. |
| Q90217010 | Biguanides Induce Acute de novo Lipogenesis in Human Primary Sebocytes |
| Q90383354 | Bilobalide Suppresses Adipogenesis in 3T3-L1 Adipocytes via the AMPK Signaling Pathway |
| Q36148555 | Bisphenol A and Bisphenol S Induce Distinct Transcriptional Profiles in Differentiating Human Primary Preadipocytes. |
| Q64117111 | Blockade of MCU-Mediated Ca Uptake Perturbs Lipid Metabolism via PP4-Dependent AMPK Dephosphorylation |
| Q34733841 | Butyrate-producing probiotics reduce nonalcoholic fatty liver disease progression in rats: new insight into the probiotics for the gut-liver axis |
| Q58549544 | CB1 receptor blockade ameliorates hepatic fat infiltration and inflammation and increases Nrf2-AMPK pathway in a rat model of severely uncontrolled diabetes |
| Q41900013 | CNX-012-570, a direct AMPK activator provides strong glycemic and lipid control along with significant reduction in body weight; studies from both diet-induced obese mice and db/db mice models |
| Q28537870 | COH-SR4 reduces body weight, improves glycemic control and prevents hepatic steatosis in high fat diet-induced obese mice |
| Q47448026 | Cafeteria diet overfeeding in young male rats impairs the adaptive response to fed/fasted conditions and increases adiposity independent of body weight. |
| Q42825794 | Calebin-A inhibits adipogenesis and hepatic steatosis in high-fat diet-induced obesity via activation of AMPK signaling |
| Q38044956 | Cannabinoid 1 receptor in fatty liver |
| Q61456088 | Cannabinoid-1 Receptor Antagonism Improves Glycemic Control and Increases Energy Expenditure via Sirt1/mTORC2 and AMPK Signaling |
| Q64080416 | Capsaicin Targets Lipogenesis in HepG2 Cells Through AMPK Activation, AKT Inhibition and PPARs Regulation |
| Q39379798 | Cardiovascular disease and cancer: Evidence for shared disease pathways and pharmacologic prevention. |
| Q60953865 | Carnosic Acid Modulates Increased Hepatic Lipogenesis and Adipocytes Differentiation in Ovariectomized Mice Fed Normal or High-Fat Diets |
| Q37536508 | Casein kinase 1 regulates sterol regulatory element-binding protein (SREBP) to control sterol homeostasis |
| Q95265626 | Catalpol Attenuates Hepatic Steatosis by Regulating Lipid Metabolism via AMP-Activated Protein Kinase Activation |
| Q37571401 | Celastrol ameliorates liver metabolic damage caused by a high-fat diet through Sirt1. |
| Q27013561 | Cellular and molecular mechanisms of metformin: an overview |
| Q50052083 | Chalcones suppress fatty acid-induced lipid accumulation through a LKB1/AMPK signaling pathway in HepG2 cells |
| Q57940190 | Chemoproteomics reveals baicalin activates hepatic CPT1 to ameliorate diet-induced obesity and hepatic steatosis |
| Q49951009 | Chinese olive extract ameliorates hepatic lipid accumulation in vitro and in vivo by regulating lipid metabolism |
| Q36918682 | Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function |
| Q89728169 | Circadian Rhythms in the Pathogenesis and Treatment of Fatty Liver Disease |
| Q38187003 | Circadian clocks and energy metabolism |
| Q41420644 | Coenzyme Q10 Improves Lipid Metabolism and Ameliorates Obesity by Regulating CaMKII-Mediated PDE4 Inhibition |
| Q98178002 | Colchicine Alleviates Cholesterol Crystal-Induced Endothelial Cell Pyroptosis through Activating AMPK/SIRT1 Pathway |
| Q36773746 | Combined pharmacological activation of AMPK and PPARδ potentiates the effects of exercise in trained mice |
| Q38297306 | Combining citrulline with atorvastatin preserves glucose homeostasis in a murine model of diet-induced obesity |
| Q38072272 | Coming full circle in diabetes mellitus: from complications to initiation. |
| Q41620998 | Comparative transcriptome analysis of the Pacific White Shrimp (Litopenaeus vannamei) muscle reveals the molecular basis of residual feed intake |
| Q90112589 | Compounds that modulate AMPK activity and hepatic steatosis impact the biosynthesis of microRNAs required to maintain lipid homeostasis in hepatocytes |
| Q37240377 | Conserved versatile master regulators in signalling pathways in response to stress in plants. |
| Q59034641 | Consumption of Chinese tea-flavor liquor improves circulating insulin levels without affecting hepatic lipid metabolism-related gene expression in Sprague-Dawley rats |
| Q34477493 | Counteracting roles of AMP deaminase and AMP kinase in the development of fatty liver |
| Q92253219 | Critical role of AMPK in redox regulation under glucose starvation |
| Q34479148 | Cross regulation of sirtuin 1, AMPK, and PPARγ in conjugated linoleic acid treated adipocytes |
| Q49982517 | Crosstalk of Hyperglycemia and Dyslipidemia in Diabetic Kidney Disease |
| Q33809697 | Crude extracts from Lycium barbarum suppress SREBP-1c expression and prevent diet-induced fatty liver through AMPK activation |
| Q35982174 | Crude triterpenoid saponins from Ilex latifolia (Da Ye Dong Qing) ameliorate lipid accumulation by inhibiting SREBP expression via activation of AMPK in a non-alcoholic fatty liver disease model |
| Q51076181 | Curcumin attenuates diet-induced hepatic steatosis by activating AMP-activated protein kinase. |
| Q97526776 | Current Evidences and Future Perspectives for AMPK in the Regulation of Milk Production and Mammary Gland Biology |
| Q93016060 | Cytochrome P450 endoplasmic reticulum-associated degradation (ERAD): therapeutic and pathophysiological implications |
| Q49850633 | DEPTOR Suppresses Lipogenesis and Ameliorates Hepatic Steatosis and Acute-on-Chronic Liver Injury in Alcoholic Liver Disease |
| Q38162438 | Dealing with hunger: Metabolic stress responses in tumors |
| Q53752831 | Decreased lipid metabolism but increased FA biosynthesis are coupled with changes in liver microRNAs in obese subjects with NAFLD. |
| Q92709339 | Deletion of OSBPL2 in auditory cells increases cholesterol biosynthesis and drives reactive oxygen species production by inhibiting AMPK activity |
| Q58789506 | Delphinidin Ameliorates Hepatic Triglyceride Accumulation in Human HepG2 Cells, but Not in Diet-Induced Obese Mice |
| Q40972365 | Dieckol, a major phlorotannin in Ecklonia cava, suppresses lipid accumulation in the adipocytes of high-fat diet-fed zebrafish and mice: Inhibition of early adipogenesis via cell-cycle arrest and AMPKα activation |
| Q91867502 | Dietary Bile Acids Enhance Growth, and Alleviate Hepatic Fibrosis Induced by a High Starch Diet via AKT/FOXO1 and cAMP/AMPK/SREBP1 Pathway in Micropterus salmoides |
| Q38595529 | Dietary Broccoli Lessens Development of Fatty Liver and Liver Cancer in Mice Given Diethylnitrosamine and Fed a Western or Control Diet. |
| Q48278156 | Dietary flavones counteract phorbol 12-myristate 13-acetate-induced SREBP-2 processing in hepatic cells |
| Q90098408 | Diosgenin ameliorates palmitic acid-induced lipid accumulation via AMPK/ACC/CPT-1A and SREBP-1c/FAS signaling pathways in LO2 cells |
| Q54976746 | Discovery of pancreastatin inhibitor PSTi8 for the treatment of insulin resistance and diabetes: studies in rodent models of diabetes mellitus. |
| Q59794101 | Disease-modifying effects of metabolic perturbations in ALS/FTLD |
| Q47217999 | Disruption of Adenosine 2A Receptor Exacerbates NAFLD through Increasing Inflammatory Responses and SREBP1c Activity |
| Q33682914 | Dissecting the role of AMP-activated protein kinase in human diseases |
| Q90597139 | Distinct Gut Microbiota Induced by Different Fat-to-Sugar-Ratio High-Energy Diets Share Similar Pro-obesity Genetic and Metabolite Profiles in Prediabetic Mice |
| Q42578957 | Down-regulation of HSP60 Suppresses the Proliferation of Glioblastoma Cells via the ROS/AMPK/mTOR Pathway |
| Q89992547 | Dysregulated lipid metabolism in hepatocellular carcinoma cancer stem cells |
| Q90640984 | Dysregulated liver lipid metabolism and innate immunity associated with hepatic steatosis in neonatal BBdp rats and NOD mice |
| Q47390509 | Dysregulation of mRNA translation and energy metabolism in cancer. |
| Q37033133 | E4BP4 is an insulin-induced stabilizer of nuclear SREBP-1c and promotes SREBP-1c-mediated lipogenesis. |
| Q35783538 | Effect of Creosote Bush-Derived NDGA on Expression of Genes Involved in Lipid Metabolism in Liver of High-Fructose Fed Rats: Relevance to NDGA Amelioration of Hypertriglyceridemia and Hepatic Steatosis |
| Q35965770 | Effect of Octreotide on Hepatic Steatosis in Diet-Induced Obesity in Rats |
| Q64282122 | Effect of ethanol on lipid metabolism |
| Q91972512 | Effect of resveratrol on non-alcoholic fatty liver disease |
| Q91645472 | Effects of Lespedeza Bicolor Extract on Regulation of AMPK Associated Hepatic Lipid Metabolism in Type 2 Diabetic Mice |
| Q58617696 | Effects of Metformin Combined with Lactoferrin on Lipid Accumulation and Metabolism in Mice Fed with High-Fat Diet |
| Q55231905 | Effects of Oleacein on High-Fat Diet-Dependent Steatosis, Weight Gain, and Insulin Resistance in Mice. |
| Q50641017 | Effects of Viola mandshurica on Atherosclerosis and Hepatic Steatosis in ApoE[Formula: see text] via the AMPK Pathway. |
| Q33563877 | Effects of resveratrol in experimental and clinical non-alcoholic fatty liver disease |
| Q64062459 | Efficacy and Metabolic Effect on Serum Lipids of Apremilast in Psoriatic Arthritis: A Case Report |
| Q64104666 | Eicosapentaenoic Acid Improves Hepatic Metabolism and Reduces Inflammation Independent of Obesity in High-Fat-Fed Mice and in HepG2 Cells |
| Q38705146 | Eicosapentaenoic acid down-regulates expression of the selenoprotein P gene by inhibiting SREBP-1c protein independently of the AMP-activated protein kinase pathway in H4IIEC3 hepatocytes |
| Q38026353 | Emerging role of AMP-activated protein kinase in endocrine control of metabolism in the liver |
| Q51593895 | Emodin alleviates hepatic steatosis by inhibiting sterol regulatory element binding protein 1 activity by way of the calcium/calmodulin-dependent kinase kinase-AMP-activated protein kinase-mechanistic target of rapamycin-p70 ribosomal S6 kinase sign |
| Q35979123 | Emodin, a Naturally Occurring Anthraquinone Derivative, Ameliorates Dyslipidemia by Activating AMP-Activated Protein Kinase in High-Fat-Diet-Fed Rats |
| Q26852572 | Endothelial dysfunction: the role of sterol regulatory element-binding protein-induced NOD-like receptor family pyrin domain-containing protein 3 inflammasome in atherosclerosis |
| Q36619432 | Energy metabolism and energy-sensing pathways in mammalian embryonic and adult stem cell fate |
| Q26996783 | Energy metabolism in the liver |
| Q39253844 | Epigallocatechin-3-gallate improves acne in humans by modulating intracellular molecular targets and inhibiting P. acnes |
| Q26861119 | Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement |
| Q36303731 | Expanding roles for SREBP in metabolism |
| Q90494043 | Expression of SREBP2 and cholesterol metabolism related genes in TCGA glioma cohorts |
| Q64102442 | Extract Attenuates Non-Alcoholic Fatty Liver Disease in Free Fatty Acid-Induced HepG2 Hepatocytes and in High Fat Diet-Fed Mice |
| Q90167128 | FAM13A Represses AMPK Activity and Regulates Hepatic Glucose and Lipid Metabolism |
| Q38966510 | FGF21 activates AMPK signaling: impact on metabolic regulation and the aging process |
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| Q92614731 | Fatty liver formation in fulminant type 1 diabetes |
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| Q58697142 | Flavonones from Ameliorate Hepatic Steatosis by Activating the SIRT1/AMPK Pathway in HepG2 Cells |
| Q34359084 | Function of SREBP1 in the milk fat synthesis of dairy cow mammary epithelial cells |
| Q38807302 | Functional characterization of AMP-activated protein kinase signaling in tumorigenesis |
| Q48042047 | Functional interplay between LXR and AMPKα inhibits atherosclerosis in apoE deficient mice - A new anti-atherogenic strategy. |
| Q28834044 | GPR40 agonist ameliorates liver X receptor-induced lipid accumulation in liver by activating AMPK pathway |
| Q42237860 | GSK-3-mediated phosphorylation couples ER-Golgi transport and nuclear stabilization of the CREB-H transcription factor to mediate apolipoprotein secretion |
| Q41046980 | Gain-of-function mutant p53 promotes cell growth and cancer cell metabolism via inhibition of AMPK activation. |
| Q33616651 | Gelidium elegans Regulates the AMPK-PRDM16-UCP-1 Pathway and Has a Synergistic Effect with Orlistat on Obesity-Associated Features in Mice Fed a High-Fat Diet |
| Q38217467 | Gene of the month. AMP kinase (PRKAA1). |
| Q47416884 | Genistein Ameliorates Fat Accumulation Through AMPK Activation in Fatty Acid-Induced BRL Cells |
| Q34549575 | Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer |
| Q42805009 | Germacrone inhibits adipogenesis and stimulates lipolysis via the AMP-activated protein kinase signalling pathway in 3T3-L1 preadipocytes |
| Q36356220 | Ginkgolic acid suppresses the development of pancreatic cancer by inhibiting pathways driving lipogenesis |
| Q38110276 | Ginseng and diabetes: the evidences from in vitro, animal and human studies |
| Q36057216 | Ginsenoside Rg3 reduces lipid accumulation with AMP-Activated Protein Kinase (AMPK) activation in HepG2 cells |
| Q38404438 | Glu-Phe from onion (Allium Cepa L.) attenuates lipogenesis in hepatocytes |
| Q36486178 | Glucose intolerance and lipid metabolic adaptations in response to intrauterine and postnatal calorie restriction in male adult rats. |
| Q36478902 | Glycogen synthase kinase-3-mediated phosphorylation of serine 73 targets sterol response element binding protein-1c (SREBP-1c) for proteasomal degradation |
| Q35832166 | Green Tea Extract Rich in Epigallocatechin-3-Gallate Prevents Fatty Liver by AMPK Activation via LKB1 in Mice Fed a High-Fat Diet |
| Q37367844 | Group X secreted phospholipase A(2) induces lipid droplet formation and prolongs breast cancer cell survival. |
| Q41075841 | Growth hormone reverses dyslipidemia in adult offspring after maternal undernutrition |
| Q52594706 | Hepatic CREBZF Couples Insulin to Lipogenesis by Inhibiting Insig activity and Contributes to Hepatic Steatosis in Diet-Induced Insulin-Resistant Mice. |
| Q98566205 | Hepatic CREBZF as a novel transcriptional regulator of the lipogenic pathway |
| Q34494080 | Hepatic SIRT1 attenuates hepatic steatosis and controls energy balance in mice by inducing fibroblast growth factor 21. |
| Q90227054 | Hepatic Transcriptomics Reveals that Lipogenesis Is a Key Signaling Pathway in Isocitrate Dehydrogenase 2 Deficient Mice |
| Q40404141 | Hepatic fatty acid biosynthesis is more responsive to protein than carbohydrate in rainbow trout during acute stimulations |
| Q52583858 | Hepatocellular Carcinoma-associated Protein TD26 Interacts and Enhances SREBP1 Activity to Promote Tumor Cell Proliferation and Growth. |
| Q64056394 | Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα |
| Q92219736 | Hepatoprotective Effects of a Ruthenium(II) Schiff Base Complex in Rats with Diet-Induced Prediabetes |
| Q55642037 | Hexane-Isopropanolic Extract of Tungrymbai, a North-East Indian fermented soybean food prevents hepatic steatosis via regulating AMPK-mediated SREBP/FAS/ACC/HMGCR and PPARα/CPT1A/UCP2 pathways. |
| Q43529289 | Hibiscus sabdariffa L. aqueous extract attenuates hepatic steatosis through down-regulation of PPAR-γ and SREBP-1c in diet-induced obese mice |
| Q92861151 | Hierarchical activation of compartmentalized pools of AMPK depends on severity of nutrient or energy stress |
| Q37287417 | Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development |
| Q54318307 | Houttuynia cordata alleviates high-fat diet-induced non-alcoholic fatty liver in experimental rats. |
| Q51479221 | Hypolipidemic Activity of Peony Seed Oil Rich in α-Linolenic, is Mediated Through Inhibition of Lipogenesis and Upregulation of Fatty Acid β-Oxidation. |
| Q35273295 | Hypoxia induces a lipogenic cancer cell phenotype via HIF1α-dependent and -independent pathways |
| Q41627727 | IMM-H007, a new therapeutic candidate for nonalcoholic fatty liver disease, improves hepatic steatosis in hamsters fed a high-fat diet |
| Q39051113 | Identification of miR-185 as a regulator of de novo cholesterol biosynthesis and low density lipoprotein uptake |
| Q92803859 | Immunometabolic cross-talk in the inflamed heart |
| Q38998439 | In Vitro Methods to Study AMPK. |
| Q91831900 | In vitro anti-obesity effects of sesamol mediated by adenosine monophosphate-activated protein kinase and mitogen-activated protein kinase signaling in 3T3-L1 cells |
| Q36368338 | Inactivation of MARK4, an AMP-activated protein kinase (AMPK)-related kinase, leads to insulin hypersensitivity and resistance to diet-induced obesity |
| Q54977313 | Increased intracellular iron in mouse primary hepatocytes in vitro causes activation of the Akt pathway but decreases its response to insulin. |
| Q33570114 | Increased subcutaneous adipose tissue expression of genes involved in glycerolipid-fatty acid cycling in obese insulin-resistant versus -sensitive individuals |
| Q90044608 | Indole-3-propionic acid inhibits gut dysbiosis and endotoxin leakage to attenuate steatohepatitis in rats |
| Q38908236 | Inhibition of AMP Kinase by the Protein Phosphatase 2A Heterotrimer, PP2APpp2r2d |
| Q116165456 | Inhibition of AMP-activated protein kinase in respiratory syncytial virus infection activates lipid metabolism |
| Q64896938 | Inhibition of Adenosine Monophosphate-Activated Protein Kinase-3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Signaling Leads to Hypercholesterolemia and Promotes Hepatic Steatosis and Insulin Resistance. |
| Q33612522 | Inhibition of NAMPT aggravates high fat diet-induced hepatic steatosis in mice through regulating Sirt1/AMPKα/SREBP1 signaling pathway |
| Q64907904 | Inhibitory effect of esculetin on free-fatty-acid-induced lipid accumulation in human HepG2 cells through activation of AMP-activated protein kinase. |
| Q38827616 | Inhibitory effects of Aster spathulifolius extract on adipogenesis and lipid accumulation in 3T3-L1 preadipocytes |
| Q89783547 | Insights into Stearoyl-CoA Desaturase-1 Regulation of Systemic Metabolism |
| Q98165147 | Insulin and Metformin Control Cell Proliferation by Regulating TDG-Mediated DNA Demethylation in Liver and Breast Cancer Cells |
| Q28072521 | Insulin-Sensitizers, Polycystic Ovary Syndrome and Gynaecological Cancer Risk |
| Q90198375 | Insulin-induced de novo lipid synthesis occurs mainly via mTOR-dependent regulation of proteostasis of SREBP-1c |
| Q58114512 | Interactive Roles for AMPK and Glycogen from Cellular Energy Sensing to Exercise Metabolism |
| Q36336508 | Intestinal GATA4 deficiency protects from diet-induced hepatic steatosis |
| Q42216601 | Involvement of insulin resistance in the protective effect of metformin against alcoholic liver injury |
| Q54979795 | Iron overload promotes mitochondrial fragmentation in mesenchymal stromal cells from myelodysplastic syndrome patients through activation of the AMPK/MFF/Drp1 pathway. |
| Q46331739 | Isofraxidin, a coumarin component improves high-fat diet induced hepatic lipid homeostasis disorder and macrophage inflammation in mice |
| Q38963320 | Isoprenylcysteine carboxylmethyltransferase regulates mitochondrial respiration and cancer cell metabolism |
| Q60947803 | Isoquercetin Improves Hepatic Lipid Accumulation by Activating AMPK Pathway and Suppressing TGF-β Signaling on an HFD-Induced Nonalcoholic Fatty Liver Disease Rat Model |
| Q47674391 | Keeping the home fires burning: AMP-activated protein kinase. |
| Q35675145 | Korean Red Ginseng attenuates ethanol-induced steatosis and oxidative stress via AMPK/Sirt1 activation |
| Q38034266 | LKB1 and AMPK: central regulators of lymphocyte metabolism and function |
| Q64251353 | LKB1 and Tumor Metabolism: The Interplay of Immune and Angiogenic Microenvironment in Lung Cancer |
| Q48234896 | LKB1/AMPK-Mediated Regulation by Gentiopicroside Ameliorates P2x7R-Dependent Alcoholic Hepatosteatosis. |
| Q43218291 | La mort de la lipogenèse: RNF20 lashes ubiquitin to SREBP-1c |
| Q98241464 | Lack of Augmenter of Liver Regeneration Disrupts Cholesterol Homeostasis of Liver in Mice by Inhibiting the AMPK Pathway |
| Q28572488 | Leucine improves glucose and lipid status in offspring from obese dams, dependent on diet type, but not caloric intake |
| Q33554328 | Licochalcone Suppresses LXRα-Induced Hepatic Lipogenic Gene Expression through AMPK/Sirt1 Pathway Activation |
| Q39071340 | Lipid Synthesis Is a Metabolic Liability of Non-Small Cell Lung Cancer |
| Q38735369 | Lipid desaturation - the next step in targeting lipogenesis in cancer? |
| Q44835133 | Lipid metabolism fattens up hedgehog signaling |
| Q90193411 | Liraglutide Inhibits Hepatitis C Virus Replication Through an AMP Activated Protein Kinase Dependent Mechanism |
| Q42972408 | Liraglutide reduces oxidized LDL-induced oxidative stress and fatty degeneration in Raw 264.7 cells involving the AMPK/SREBP1 pathway |
| Q36255938 | Liver AMP-Activated Protein Kinase Is Unnecessary for Gluconeogenesis but Protects Energy State during Nutrient Deprivation |
| Q36898227 | Liver MicroRNA-291b-3p Promotes Hepatic Lipogenesis through Negative Regulation of Adenosine 5'-Monophosphate (AMP)-activated Protein Kinase α1. |
| Q37015068 | Liver kinase b1 is required for white adipose tissue growth and differentiation |
| Q90192279 | Liver-expressed antimicrobial peptide 2 antagonizes the effect of ghrelin in rodents |
| Q46270590 | Loss of miR-141/200c ameliorates hepatic steatosis and inflammation by reprogramming multiple signaling pathways in NASH. |
| Q37547671 | Low-ω3 Fatty Acid and Soy Protein Attenuate Alcohol-Induced Fatty Liver and Injury by Regulating the Opposing Lipid Oxidation and Lipogenic Signaling Pathways. |
| Q42293291 | Lung Adenocarcinoma Distally Rewires Hepatic Circadian Homeostasis |
| Q38995005 | Luteolin alleviates alcoholic liver disease induced by chronic and binge ethanol feeding in mice |
| Q90700017 | Lysosomes: Signaling Hubs for Metabolic Sensing and Longevity |
| Q37310248 | MSP is a negative regulator of inflammation and lipogenesis in ex vivo models of non-alcoholic steatohepatitis |
| Q28511498 | Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3 |
| Q54981861 | Mangiferin Improves Hepatic Lipid Metabolism Mainly Through Its Metabolite-Norathyriol by Modulating SIRT-1/AMPK/SREBP-1c Signaling. |
| Q37163024 | Map4k4 suppresses Srebp-1 and adipocyte lipogenesis independent of JNK signaling |
| Q41682399 | Maternal resveratrol intake during lactation attenuates hepatic triglyceride and fatty acid synthesis in adult male rat offspring |
| Q92059973 | Mechanisms and regulation of cholesterol homeostasis |
| Q47330256 | Mechanisms of AMPK in the maintenance of ATP balance during energy metabolism |
| Q64059484 | Mechanisms of Adiponectin Action: Implication of Adiponectin Receptor Agonism in Diabetic Kidney Disease |
| Q37180829 | Mechanisms of current therapies for diabetes mellitus type 2 |
| Q89495857 | Mechanisms underlying the attenuation of chronic inflammatory diseases by aged garlic extract: Involvement of the activation of AMP-activated protein kinase |
| Q58705769 | Metabolic Plasticity of Tumor Cell Mitochondria |
| Q51835057 | Metabolic adaptations to HFHS overfeeding: how whole body and tissues postprandial metabolic flexibility adapt in Yucatan mini-pigs. |
| Q92701392 | Metabolic and Epigenetic Action Mechanisms of Antidiabetic Medicinal Plants |
| Q38862319 | Metabolic control of the proteotoxic stress response: implications in diabetes mellitus and neurodegenerative disorders |
| Q38674284 | Metabolic reprogramming: a hallmark of viral oncogenesis. |
| Q40065267 | Metabolism in Immune Cell Differentiation and Function. |
| Q27330478 | Metabolism. AMP-activated protein kinase mediates mitochondrial fission in response to energy stress |
| Q92776030 | Metformin Attenuates Liver Fat Content: Finding from Schizophrenia Patients with Olanzapine-induced Weight Gain |
| Q39225251 | Metformin Reduces Lipogenesis Markers in Obese Mice Fed a Low-Carbohydrate and High-Fat Diet |
| Q44630049 | Metformin Suppressed CXCL8 Expression and Cell Migration in HEK293/TLR4 Cell Line. |
| Q35123211 | Metformin ameliorates hepatic steatosis and inflammation without altering adipose phenotype in diet-induced obesity |
| Q28082736 | Metformin and metabolic diseases: a focus on hepatic aspects |
| Q64080514 | Metformin attenuates the onset of non-alcoholic fatty liver disease and affects intestinal microbiota and barrier in small intestine |
| Q54979135 | Metformin attenuates triglyceride accumulation in HepG2 cells through decreasing stearyl-coenzyme A desaturase 1 expression. |
| Q60914133 | Metformin exhibited anticancer activity by lowering cellular cholesterol content in breast cancer cells |
| Q22242884 | Metformin in reproductive health, pregnancy and gynaecological cancer: established and emerging indications |
| Q64083613 | Metformin inhibits both oleic acid-induced and CB1R receptor agonist-induced lipid accumulation in Hep3B cells: The preliminary report |
| Q37570847 | Metformin inhibits skin tumor promotion in overweight and obese mice |
| Q35793665 | Metformin prevents aggressive ovarian cancer growth driven by high-energy diet: similarity with calorie restriction |
| Q38393435 | Metformin, an old drug, brings a new era to cancer therapy |
| Q36021086 | Metformin-induced energy deficiency leads to the inhibition of lipogenesis in prostate cancer cells |
| Q38756907 | Metformin: A Hopeful Promise in Aging Research |
| Q48267205 | MicroRNA-7 mediates cross-talk between metabolic signaling pathways in the liver. |
| Q41850658 | MicroRNAs in metabolism and metabolic diseases |
| Q33612997 | MicroRNAs in metabolism and metabolic disorders |
| Q39042066 | Modulation of lipogenesis and glucose consumption in HepG2 cells and C2C12 myotubes by sophoricoside. |
| Q95841469 | Molecular Mechanisms of Adipogenesis: The Anti-adipogenic Role of AMP-Activated Protein Kinase |
| Q36049827 | Molecular mechanisms of estrogen receptors' suppression of lipogenesis in pancreatic β-cells |
| Q96304541 | NF- κ B/HDAC1/SREBP1c pathway mediates the inflammation signal in progression of hepatic steatosis |
| Q49325511 | Natural products, an important resource for discovery of multitarget drugs and functional food for regulation of hepatic glucose metabolism |
| Q98222131 | Neohesperidin enhances PGC-1α-mediated mitochondrial biogenesis and alleviates hepatic steatosis in high fat diet fed mice |
| Q58121145 | New insights into oxidative stress and inflammation during diabetes mellitus-accelerated atherosclerosis |
| Q33757267 | New therapeutic targets in alcoholic hepatitis |
| Q35929036 | Nicotinamide N-methyltransferase regulates hepatic nutrient metabolism through Sirt1 protein stabilization. |
| Q47904028 | Nischarin inhibition alters energy metabolism by activating AMP-activated protein kinase |
| Q52725877 | Nobiletin Inhibits Hepatic Lipogenesis via Activation of AMP-Activated Protein Kinase. |
| Q42674175 | Nogo-B receptor deficiency increases liver X receptor alpha nuclear translocation and hepatic lipogenesis through an adenosine monophosphate-activated protein kinase alpha-dependent pathway |
| Q44748085 | Non-esterified fatty acids activate the AMP-activated protein kinase signaling pathway to regulate lipid metabolism in bovine hepatocytes |
| Q36527942 | Nordihydroguaiaretic acid improves metabolic dysregulation and aberrant hepatic lipid metabolism in mice by both PPARα-dependent and -independent pathways |
| Q46754499 | Novel effect of ezetimibe to inhibit the development of non-alcoholic fatty liver disease in Fatty Liver Shionogi mouse |
| Q37660915 | Novel osmotin inhibits SREBP2 via the AdipoR1/AMPK/SIRT1 pathway to improve Alzheimer's disease neuropathological deficits |
| Q33680596 | Nox2 mediates high fat high sucrose diet-induced nitric oxide dysfunction and inflammation in aortic smooth muscle cells |
| Q36732028 | Nuclear receptors reverse McGarry's vicious cycle to insulin resistance |
| Q27024772 | Nutrient sensing, metabolism, and cell growth control |
| Q47616537 | Nutrient sensor O-GlcNAc transferase controls cancer lipid metabolism via SREBP-1 regulation |
| Q27011433 | Nutrient-sensing pathways and metabolic regulation in stem cells |
| Q49980779 | O-GlcNAcylation: key regulator of glycolytic pathways |
| Q33919545 | OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin. |
| Q92253378 | OSBPL2 deficiency upregulate SQLE expression increasing intracellular cholesterol and cholesteryl ester by AMPK/SP1 and SREBF2 signalling pathway |
| Q34297407 | Obesity-dependent dysregulation of glucose homeostasis in kinase suppressor of ras 2-/- mice |
| Q40623445 | Ogg1-Dependent DNA Repair Regulates NLRP3 Inflammasome and Prevents Atherosclerosis |
| Q38876119 | Omics-based approaches to understand mechanosensitive endothelial biology and atherosclerosis |
| Q50212100 | Optimized Analysis of In Vivo and In Vitro Hepatic Steatosis |
| Q58800011 | Paeoniflorin Ameliorates Fructose-Induced Insulin Resistance and Hepatic Steatosis by Activating LKB1/AMPK and AKT Pathways |
| Q94461629 | Partial impairment of insulin receptor expression mimics fasting to prevent diet-induced fatty liver disease |
| Q34449857 | Pathogenesis and therapeutic approaches for non-alcoholic fatty liver disease |
| Q46484710 | Perilipin-2 Deletion Impairs Hepatic Lipid Accumulation by Interfering with Sterol Regulatory Element-binding Protein (SREBP) Activation and Altering the Hepatic Lipidome |
| Q90036169 | Peroxiredoxin 5 ameliorates obesity-induced non-alcoholic fatty liver disease through the regulation of oxidative stress and AMP-activated protein kinase signaling |
| Q46708537 | Phosphorylation of PRAS40-Thr246 involved in renal lipid accumulation of diabetes |
| Q48044638 | Phosphorylation of WRINKLED1 by KIN10 Results in Its Proteasomal Degradation, Providing a Link between Energy Homeostasis and Lipid Biosynthesis. |
| Q90663261 | Plasmodium Infection Induces Dyslipidemia and a Hepatic Lipogenic State in the Host through the Inhibition of the AMPK-ACC Pathway |
| Q91710772 | Polyphenol-rich Trapa quadrispinosa pericarp extract ameliorates high-fat diet induced non-alcoholic fatty liver disease by regulating lipid metabolism and insulin resistance in mice |
| Q61798021 | Post-translational regulation of lipogenesis via AMPK-dependent phosphorylation of insulin-induced gene |
| Q48199112 | Potential of rooibos, its major C-glucosyl flavonoids, and Z-2-(β-D-glucopyranosyloxy)-3-phenylpropenoic acid in prevention of metabolic syndrome |
| Q34182797 | Preventing phosphorylation of sterol regulatory element-binding protein 1a by MAP-kinases protects mice from fatty liver and visceral obesity |
| Q39014997 | Protective effect of resveratrol derivatives on high-fat diet induced fatty liver by activating AMP-activated protein kinase |
| Q39014996 | Protein kinases: mechanisms and downstream targets in inflammation-mediated obesity and insulin resistance |
| Q40756895 | Protein phosphatase 2A (PP2A) regulates low density lipoprotein uptake through regulating sterol response element-binding protein-2 (SREBP-2) DNA binding |
| Q92099759 | Pterostilbene reduces endothelial cell injury in vascular arterial walls by regulating the Nrf2-mediated AMPK/STAT3 pathway in an atherosclerosis rat model |
| Q60925304 | Quercetin induces cell death in cervical cancer by reducing O-GlcNAcylation of adenosine monophosphate-activated protein kinase |
| Q91635371 | Recent Insights Into SREBP as a Direct Mediator of Kidney Fibrosis via Lipid-Independent Pathways |
| Q58117073 | Reciprocal Regulation of AMPK/SNF1 and Protein Acetylation |
| Q59812725 | Red pepper seed water extract inhibits preadipocyte differentiation and induces mature adipocyte apoptosis in 3T3-L1 cells |
| Q57065546 | Regulation and Metabolic Significance of Lipogenesis in Adipose Tissues |
| Q26740291 | Regulation and function of AMPK in physiology and diseases |
| Q38998393 | Regulation of Carbohydrate Metabolism, Lipid Metabolism, and Protein Metabolism by AMPK. |
| Q26766488 | Regulation of glucose metabolism from a liver-centric perspective |
| Q35659167 | Regulation of hepatic lipin-1 by ethanol: role of AMP-activated protein kinase/sterol regulatory element-binding protein 1 signaling in mice |
| Q91813163 | Regulatory T cells suppress excessive lipid accumulation in alcoholic liver disease |
| Q36291200 | Resveratrol as a calorie restriction mimetic: therapeutic implications |
| Q42701853 | Resveratrol improves hepatic steatosis by inducing autophagy through the cAMP signaling pathway |
| Q46317478 | Resveratrol improves high-fat diet induced fatty liver and insulin resistance by concomitantly inhibiting proteolytic cleavage of sterol regulatory element-binding proteins, free fatty acid oxidation, and intestinal triglyceride absorption |
| Q36760335 | Retinoic acid receptor β stimulates hepatic induction of fibroblast growth factor 21 to promote fatty acid oxidation and control whole-body energy homeostasis in mice |
| Q53394107 | Retinoic acid receptor-related orphan receptor α-induced activation of adenosine monophosphate-activated protein kinase results in attenuation of hepatic steatosis. |
| Q34643735 | Ring finger protein20 regulates hepatic lipid metabolism through protein kinase A-dependent sterol regulatory element binding protein1c degradation |
| Q42247586 | Role for sterol regulatory element binding protein-1c activation in mediating skeletal muscle insulin resistance via repression of rat insulin receptor substrate-1 transcription |
| Q57066893 | Role of SREBPs in Liver Diseases: A Mini-review |
| Q26746981 | Role of Transcription Factors in Steatohepatitis and Hypertension after Ethanol: The Epicenter of Metabolism |
| Q36545745 | Role of cystathionine beta synthase in lipid metabolism in ovarian cancer |
| Q38639953 | Roles of leptin, adiponectin and resistin in the transcriptional regulation of steroidogenic genes contributing to decreased Leydig cells function in obesity. |
| Q46254073 | Root bark of Ulmus davidiana var. japonica restrains acute alcohol-induced hepatic steatosis onset in mice by inhibiting ROS accumulation. |
| Q64966841 | SCAP/SREBPs are Central Players in Lipid Metabolism and Novel Metabolic Targets in Cancer Therapy. |
| Q36406416 | SREBP and MDT-15 protect C. elegans from glucose-induced accelerated aging by preventing accumulation of saturated fat |
| Q34506085 | SREBP-1 transcription factors regulate skeletal muscle cell size by controlling protein synthesis through myogenic regulatory factors |
| Q60306278 | SREBP-2, a new target of metformin? |
| Q47094029 | SREBP-2-driven transcriptional activation of human SND1 oncogene |
| Q47692117 | SREBP-regulated lipid metabolism: convergent physiology - divergent pathophysiology |
| Q37966406 | SREBPs: metabolic integrators in physiology and metabolism |
| Q49991307 | Safety and efficacy of metformin up-titration in Japanese patients with type 2 diabetes mellitus treated with vildagliptin and low-dose metformin |
| Q35536371 | Salicylate improves macrophage cholesterol homeostasis via activation of Ampk. |
| Q35846190 | Salidroside ameliorates insulin resistance through activation of a mitochondria-associated AMPK/PI3K/Akt/GSK3β pathway. |
| Q60920829 | Salt Induces Adipogenesis/Lipogenesis and Inflammatory Adipocytokines Secretion in Adipocytes |
| Q54982120 | Scutellaria baicalensis regulates FFA metabolism to ameliorate NAFLD through the AMPK-mediated SREBP signaling pathway. |
| Q92012498 | Semen Cuscutae Administration Improves Hepatic Lipid Metabolism and Adiposity in High Fat Diet-Induced Obese Mice |
| Q93007541 | Sesamol Alleviates Obesity-Related Hepatic Steatosis via Activating Hepatic PKA Pathway |
| Q34372569 | Sestrins orchestrate cellular metabolism to attenuate aging |
| Q41484686 | Silencing of solute carrier family 13 member 5 disrupts energy homeostasis and inhibits proliferation of human hepatocarcinoma cells |
| Q38949811 | Silibinin inhibits aberrant lipid metabolism, proliferation and emergence of androgen-independence in prostate cancer cells via primarily targeting the sterol response element binding protein 1. |
| Q34990117 | Simvastatin induced neurite outgrowth unveils role of cell surface cholesterol and acetyl CoA carboxylase in SH-SY5Y cells |
| Q99555718 | Sinensol-C Isolated from Spiranthes sinensis Inhibits Adipogenesis in 3T3-L1 Cells through the Regulation of Adipogenic Transcription Factors and AMPK Activation |
| Q34657137 | Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin. |
| Q52161914 | Snf1/AMPK is involved in the mitotic spindle alignment in Saccharomyces cerevisiae |
| Q53240953 | Sorghum extract exerts cholesterol-lowering effects through the regulation of hepatic cholesterol metabolism in hypercholesterolemic mice. |
| Q64063164 | Sterol regulatory element binding protein 1 couples mechanical cues and lipid metabolism |
| Q37233061 | Sterol regulatory element binding protein 2 activation of NLRP3 inflammasome in endothelium mediates hemodynamic-induced atherosclerosis susceptibility. |
| Q37608436 | Sterol regulatory element-binding protein-1 (SREBP-1) is required to regulate glycogen synthesis and gluconeogenic gene expression in mouse liver |
| Q38925816 | Suppression of Rho-kinase 1 is responsible for insulin regulation of the AMPK/SREBP-1c pathway in skeletal muscle cells exposed to palmitate |
| Q91619033 | Suppression of myopathic lamin mutations by muscle-specific activation of AMPK and modulation of downstream signaling |
| Q35116609 | Suppression of the HSF1-mediated proteotoxic stress response by the metabolic stress sensor AMPK |
| Q35857713 | Sustained antidiabetic effects of a berberine-containing Chinese herbal medicine through regulation of hepatic gene expression. |
| Q54117369 | Synergistic effect of phytochemicals on cholesterol metabolism and lipid accumulation in HepG2 cells. |
| Q28085535 | Systematic review: Preventive and therapeutic applications of metformin in liver disease |
| Q37116046 | TAK1 regulates hepatic lipid homeostasis through SREBP |
| Q37426665 | Tangshen formula attenuates hepatic steatosis by inhibiting hepatic lipogenesis and augmenting fatty acid oxidation in db/db mice |
| Q90287748 | Tankyrase disrupts metabolic homeostasis and promotes tumorigenesis by inhibiting LKB1-AMPK signalling |
| Q34345128 | Targeted inactivation of GPR26 leads to hyperphagia and adiposity by activating AMPK in the hypothalamus |
| Q53623815 | Targeting AMPK signalling pathway with natural medicines for atherosclerosis therapy: an integration of in silico screening and in vitro assay. |
| Q99712026 | Targeting SREBP-2-Regulated Mevalonate Metabolism for Cancer Therapy |
| Q36548517 | Targeting arginase-II protects mice from high-fat-diet-induced hepatic steatosis through suppression of macrophage inflammation |
| Q41339882 | Targeting metabolism and AMP-activated kinase with metformin to sensitize non-small cell lung cancer (NSCLC) to cytotoxic therapy: translational biology and rationale for current clinical trials |
| Q38995015 | Targeting of AMP-activated protein kinase: prospects for computer-aided drug design |
| Q37506032 | Targeting the LKB1 tumor suppressor |
| Q37981833 | Targeting tumor cell metabolism with statins. |
| Q38594411 | The AMPK enzyme-complex: from the regulation of cellular energy homeostasis to a possible new molecular target in the management of chronic inflammatory disorders |
| Q24616273 | The AMPK signalling pathway coordinates cell growth, autophagy and metabolism |
| Q41876453 | The Dipeptidyl Peptidase-4 Inhibitor Teneligliptin Attenuates Hepatic Lipogenesis via AMPK Activation in Non-Alcoholic Fatty Liver Disease Model Mice |
| Q93078996 | The ER-localized Ca2+-binding protein calreticulin couples ER stress to autophagy by associating with microtubule-associated protein 1A/1B light chain 3 |
| Q35753820 | The Flavone Luteolin Suppresses SREBP-2 Expression and Post-Translational Activation in Hepatic Cells |
| Q37216964 | The Hippo pathway, p53 and cholesterol |
| Q36127235 | The Korean herbal medicine, Do In Seung Gi-Tang, attenuates atherosclerosis via AMPK in high-fat diet-induced ApoE(-/-) mice |
| Q36783013 | The LATS2 tumor suppressor inhibits SREBP and suppresses hepatic cholesterol accumulation |
| Q47099823 | The MXL-3/SBP-1 Axis Is Responsible for Glucose-Dependent Fat Accumulation in C. elegans. |
| Q37201218 | The Med1 subunit of the mediator complex induces liver cell proliferation and is phosphorylated by AMP kinase |
| Q41632623 | The PDK1 Inhibitor Dichloroacetate Controls Cholesterol Homeostasis Through the ERK5/MEF2 Pathway |
| Q95855709 | The Potential Mechanism of Wuwei Qingzhuo San against Hyperlipidemia Based on TCM Network Pharmacology and Validation Experiments in Hyperlipidemia Hamster |
| Q28078754 | The Potential Mechanisms of Berberine in the Treatment of Nonalcoholic Fatty Liver Disease |
| Q60920750 | The Potential of Isoprenoids in Adjuvant Cancer Therapy to Reduce Adverse Effects of Statins |
| Q38936241 | The Role of Glucose and Lipid Metabolism in Growth and Survival of Cancer Cells |
| Q42128185 | The anti-adiposity effect of bitter melon seed oil is solely attributed to its fatty acid components. |
| Q51309204 | The anti-obesity and anti-diabetic effects of kaempferol glycosides from unripe soybean leaves in high-fat-diet mice. |
| Q37501673 | The cell-autonomous mechanisms underlying the activity of metformin as an anticancer drug |
| Q36216100 | The chemokine CCL5 regulates glucose uptake and AMP kinase signaling in activated T cells to facilitate chemotaxis |
| Q44764083 | The effect of black seed (Nigella sativa) extract on FOXO3 expression in HepG2 cells |
| Q38096735 | The fat side of prostate cancer |
| Q38874423 | The flavone apigenin blocks nuclear translocation of sterol regulatory element-binding protein-2 in the hepatic cells WRL-68. |
| Q34951495 | The g0/g1 switch gene 2 is an important regulator of hepatic triglyceride metabolism |
| Q50557388 | The heat-shock, or HSF1-mediated proteotoxic stress, response in cancer: from proteomic stability to oncogenesis. |
| Q26850858 | The hepatic cannabinoid 1 receptor as a modulator of hepatic energy state and food intake |
| Q58705856 | The implications of signaling lipids in cancer metastasis |
| Q38937455 | The interplay between cell signalling and the mevalonate pathway in cancer |
| Q92621899 | The long-term protective effects of neonatal administration of curcumin against nonalcoholic steatohepatitis in high-fructose-fed adolescent rats |
| Q64054208 | The mevalonate coordinates energy input and cell proliferation |
| Q38559901 | The opposing actions of target of rapamycin and AMP-activated protein kinase in cell growth control |
| Q52309402 | The p53 Tumor Suppressor in the Control of Metabolism and Ferroptosis. |
| Q38321405 | The role of lipin-1 in the pathogenesis of alcoholic fatty liver |
| Q91748821 | The strange case of AMPK and cancer: Dr Jekyll or Mr Hyde? † |
| Q94544716 | The whole-transcriptome landscape of muscle and adipose tissues reveals the ceRNA regulation network related to intramuscular fat deposition in yak |
| Q93147070 | Therapeutic Mechanisms of Herbal Medicines Against Insulin Resistance: A Review |
| Q33569654 | Thyroid dysfunction associated with follicular cell steatosis in obese male mice and humans |
| Q34076176 | Tissue-specific insulin signaling in the regulation of metabolism and aging |
| Q64993840 | Traditional Herbal Formula Taeeumjowi-Tang (TJ001) Inhibits p53-Mutant Prostate Cancer Cells Growth by Activating AMPK-Dependent Pathway. |
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