Suppression of Rho-kinase 1 is responsible for insulin regulation of the AMPK/SREBP-1c pathway in skeletal muscle cells exposed to palmitate

scientific article published on 7 March 2017

Suppression of Rho-kinase 1 is responsible for insulin regulation of the AMPK/SREBP-1c pathway in skeletal muscle cells exposed to palmitate is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1084022803
P356DOI10.1007/S00592-017-0976-Z
P698PubMed publication ID28265821

P2093author name stringWenjun Wu
Hongdong Wang
Yan Bi
Dalong Zhu
Ting Hong
Sunyinyan Tang
Zhijuan Ge
Wenjuan Tang
P2860cites workRho-kinase inhibition ameliorates metabolic disorders through activation of AMPK pathway in miceQ28544668
Effect of early insulin therapy on nuclear factor kappaB and cytokine gene expressions in the liver and skeletal muscle of high-fat diet, streptozotocin-treated diabetic ratsQ28580360
AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant miceQ28591122
Inhibition of obesity-induced hepatic ER stress by early insulin therapy in obese diabetic ratsQ34103753
Lipid-induced Muscle Insulin Resistance Is Mediated by GGPPS via Modulation of the RhoA/Rho Kinase Signaling PathwayQ35953069
p70S6 kinase phosphorylates AMPK on serine 491 to mediate leptin's effect on food intakeQ36125261
Expanding roles for SREBP in metabolismQ36303731
AMP-activated protein kinase and the regulation of glucose transportQ36528251
Ablation of AMP-activated protein kinase alpha2 activity exacerbates insulin resistance induced by high-fat feeding of miceQ36943709
Increased Rho kinase activity in a Taiwanese population with metabolic syndromeQ37041722
Insulin resistance and fuel homeostasis: the role of AMP-activated protein kinaseQ37401940
ROCK1 isoform-specific deletion reveals a role for diet-induced insulin resistanceQ37575422
The Akt-SREBP nexus: cell signaling meets lipid metabolism.Q37684518
Insulin therapy stimulates lipid synthesis and improves endocrine functions of adipocytes in dietary obese C57BL/6 miceQ37728180
Rho kinase inhibitors: potential treatments for diabetes and diabetic complicationsQ38008742
Oxidative stress and macrophage foam cell formation during diabetes mellitus-induced atherogenesis: role of insulin therapyQ38034386
Free fatty acids and skeletal muscle insulin resistanceQ38174294
In vivo regulation of SREBP-1c in skeletal muscle: effects of nutritional status, glucose, insulin, and leptinQ38344056
Role of Rho-kinase in regulation of insulin action and glucose homeostasis.Q40385744
Insulin signaling: inositol phosphates get into the Akt.Q41841387
Role for sterol regulatory element binding protein-1c activation in mediating skeletal muscle insulin resistance via repression of rat insulin receptor substrate-1 transcriptionQ42247586
Intramyocitic lipid accumulation and SREBP-1c expression are related to insulin resistance and cardiovascular risk in morbid obesityQ44574966
Increased carnitine palmitoyl transferase 1 expression and decreased sterol regulatory element-binding protein 1c expression are associated with reduced intramuscular triglyceride accumulation after insulin therapy in high-fat-diet and streptozotociQ46046290
Effects of glucagon-like peptide-1 on advanced glycation endproduct-induced aortic endothelial dysfunction in streptozotocin-induced diabetic rats: possible roles of Rho kinase- and AMP kinase-mediated nuclear factor κB signaling pathwaysQ46611689
Intensive insulin therapy reduces small dense low-density lipoprotein particles in patients with type 2 diabetes mellitus: relationship to triglyceride-rich lipoprotein subspecies.Q51496235
Opposing roles of nitric oxide and rho-kinase in lipid metabolism in mice.Q54285467
P433issue7
P921main subjectskeletal muscle cellQ66505052
P304page(s)635-644
P577publication date2017-03-07
P1433published inActa DiabetologicaQ15749690
P1476titleSuppression of Rho-kinase 1 is responsible for insulin regulation of the AMPK/SREBP-1c pathway in skeletal muscle cells exposed to palmitate
P478volume54

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cites work (P2860)
Q96607232Effects of Agaricus blazei Murrill polysaccharides on hyperlipidemic rats by regulation of intestinal microflora
Q89944024Modulation of Fatty Acid-Related Genes in the Response of H9c2 Cardiac Cells to Palmitate and n-3 Polyunsaturated Fatty Acids
Q64935603Rho GTPases-Emerging Regulators of Glucose Homeostasis and Metabolic Health.

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