AMPK activation caused by reduced liver lactate metabolism protects against hepatic steatosis in MCT1 haploinsufficient mice.

scientific article published on 20 October 2017

AMPK activation caused by reduced liver lactate metabolism protects against hepatic steatosis in MCT1 haploinsufficient mice. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.MOLMET.2017.10.005
P932PMC publication ID5699913
P698PubMed publication ID29092796

P50authorLuc PellerinQ41241332
François R JornayvazQ47154382
Corinne LeloupQ52147279
Lionel CarneiroQ57542612
P2093author name stringMohamed Asrih
Christine Sempoux
Jean-Christophe Stehle
Cendrine Repond
P2860cites workA RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATIONQ25939000
Energy metabolism in the liverQ26996783
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesityQ28512778
AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant miceQ28591122
Resistance to diet-induced obesity and associated metabolic perturbations in haploinsufficient monocarboxylate transporter 1 miceQ28594538
Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exerciseQ28610612
Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in miceQ29615055
Molecular mediators of hepatic steatosis and liver injuryQ29616709
Evolution of inflammation in nonalcoholic fatty liver disease: the multiple parallel hits hypothesisQ29619888
Hepatic insulin resistance in mice with hepatic overexpression of diacylglycerol acyltransferase 2Q34804981
A monocarboxylate transporter required for hepatocyte secretion of ketone bodies during fastingQ35755173
Deficiency in myeloid differentiation factor-2 and toll-like receptor 4 expression attenuates nonalcoholic steatohepatitis and fibrosis in miceQ35825858
Diacylglycerol activation of protein kinase Cε and hepatic insulin resistanceQ35964800
cDNA cloning of MCT2, a second monocarboxylate transporter expressed in different cells than MCT1.Q36713248
AMPK, insulin resistance, and the metabolic syndromeQ36966839
Tissue-selective estrogen complexes with bazedoxifene prevent metabolic dysfunction in female mice.Q37636428
High-fat diet-induced obesity in animal modelsQ37803278
Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitisQ37953770
Current treatment options for nonalcoholic fatty liver disease and nonalcoholic steatohepatitisQ38020492
Mitochondrial adaptations and dysfunctions in nonalcoholic fatty liver diseaseQ38072666
The SLC16 gene family - structure, role and regulation in health and diseaseQ38090778
Obesity-associated nonalcoholic fatty liver disease.Q38166052
Monocarboxylate transporters: new players in body weight regulation.Q38329499
A concise review of non-alcoholic fatty liver diseaseQ38330913
Non-alcoholic Fatty Liver Disease (NAFLD)--A ReviewQ38653520
Targeting ceramide metabolism in obesityQ38887432
Exercise Inducible Lactate Dehydrogenase B Regulates Mitochondrial Function in Skeletal MuscleQ46354018
Overproduction of large VLDL particles is driven by increased liver fat content in man.Q46931621
A common bicyclic protein kinase cascade inactivates the regulatory enzymes of fatty acid and cholesterol biosynthesisQ69907652
Nonalcoholic fatty liver diseaseQ80865584
P433issue12
P921main subjectHaploinsufficiencyQ852654
steatosisQ1365091
P304page(s)1625-1633
P577publication date2017-10-20
P1433published inMolecular MetabolismQ27724805
P1476titleAMPK activation caused by reduced liver lactate metabolism protects against hepatic steatosis in MCT1 haploinsufficient mice
P478volume6

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cites work (P2860)
Q89939659Guidelines and Considerations for Metabolic Tolerance Tests in Mice
Q64091126Insulin Controls Triacylglycerol Synthesis through Control of Glycerol Metabolism and Despite Increased Lipogenesis
Q55482826Neonatal overfeeding induced glucocorticoid overexposure accelerates hepatic lipogenesis in male rats.
Q92621899The long-term protective effects of neonatal administration of curcumin against nonalcoholic steatohepatitis in high-fructose-fed adolescent rats

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