AMPK couples p73 with p53 in cell fate decision.

scientific article published on 30 May 2014

AMPK couples p73 with p53 in cell fate decision. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1031066003
P356DOI10.1038/CDD.2014.60
P932PMC publication ID4131177
P698PubMed publication ID24874608
P5875ResearchGate publication ID262787398

P50authorNina ReuvenQ85894640
P2093author name stringJ Adler
Y Shaul
V Meltser
Y Adamovich
P2860cites workComplexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascadeQ21245891
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damageQ22010200
p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damageQ22010201
Role of AMP-activated protein kinase in mechanism of metformin actionQ22241898
Physical interaction with Yes-associated protein enhances p73 transcriptional activityQ24291023
The ubiquitin-protein ligase Itch regulates p73 stabilityQ24293071
ASPP1 and ASPP2: common activators of p53 family membersQ24305256
Yap1 phosphorylation by c-Abl is a critical step in selective activation of proapoptotic genes in response to DNA damageQ24314457
Mdm2 promotes the rapid degradation of p53Q24322597
AMPK phosphorylation of raptor mediates a metabolic checkpointQ24329244
Regulation of p53 stability by Mdm2Q27860744
A serine/threonine kinase gene defective in Peutz-Jeghers syndromeQ28119198
Interaction of c-Abl and p73alpha and their collaboration to induce apoptosisQ28138604
Interaction between ATM protein and c-Abl in response to DNA damageQ28239339
Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinaseQ28258611
E1A activates transcription of p73 and Noxa to induce apoptosisQ28295846
A mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73Q28305429
LKB1 is the upstream kinase in the AMP-activated protein kinase cascadeQ28610414
p73 as a pharmaceutical target for cancer therapyQ28611414
Requirement for p53 and p21 to sustain G2 arrest after DNA damageQ29547667
The LKB1-AMPK pathway: metabolism and growth control in tumour suppressionQ29617506
5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells?Q29618095
AMP-activated protein kinase induces a p53-dependent metabolic checkpointQ29618123
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alphaQ29620443
Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiationQ29871427
Phosphoprotein analysis using antibodies broadly reactive against phosphorylated motifsQ31100056
AMP-activated protein kinase: the energy charge hypothesis revisitedQ33183179
Kinase activity-independent suppression of p73alpha by AMP-activated kinase alpha (AMPKalpha).Q33392580
AMP-activated protein kinase-deficient mice are resistant to the metabolic effects of resveratrolQ33688533
The transcriptional coactivator Yes-associated protein drives p73 gene-target specificity in response to DNA Damage.Q34418866
The Yes-associated protein 1 stabilizes p73 by preventing Itch-mediated ubiquitination of p73.Q34582482
Regulation of p73 activity by post-translational modificationsQ35865249
Ubiquitin-dependent degradation of p73 is inhibited by PML.Q36399088
p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress.Q36443527
AMPK and cell proliferation--AMPK as a therapeutic target for atherosclerosis and cancerQ36448932
RETRACTED: p73alpha regulation by Chk1 in response to DNA damageQ37056579
AMP-activated protein kinase and human cancer: cancer metabolism revisitedQ37249341
The p53 family protein p73 provides new insights into cancer chemosensitivity and targeting.Q37622615
LKB1/AMPK/mTOR signaling pathway in hematological malignancies: from metabolism to cancer cell biology.Q37875635
Nuclear import and export signals in control of the p53-related protein p73.Q38292032
p73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2.Q38333104
PML, YAP, and p73 are components of a proapoptotic autoregulatory feedback loop.Q38357857
A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domainQ39458140
The regulation of p53 by phosphorylation: a model for how distinct signals integrate into the p53 pathwayQ39739160
ATM-dependent nuclear accumulation of IKK-alpha plays an important role in the regulation of p73-mediated apoptosis in response to cisplatinQ40093533
p73 Induces apoptosis via PUMA transactivation and Bax mitochondrial translocationQ40614201
Regulation of p73 by c-Abl through the p38 MAP kinase pathway.Q40751506
Cell cycle regulation via p53 phosphorylation by a 5'-AMP activated protein kinase activator, 5-aminoimidazole- 4-carboxamide-1-beta-D-ribofuranoside, in a human hepatocellular carcinoma cell lineQ40780866
Regulation of p73-mediated apoptosis by c-Jun N-terminal kinaseQ43075879
Protein kinase substrate recognition studied using the recombinant catalytic domain of AMP-activated protein kinase and a model substrate.Q43922758
Activation of AMP-activated protein kinase induces p53-dependent apoptotic cell death in response to energetic stressQ46868426
c-Abl tyrosine kinase selectively regulates p73 nuclear matrix associationQ47807561
Physical and Functional Interaction between p53 Mutants and Different Isoforms of p73Q58073315
p73β Is Regulated by Protein Kinase Cδ Catalytic Fragment Generated in the Apoptotic Response to DNA DamageQ58662170
P433issue9
P304page(s)1451-1459
P577publication date2014-05-30
P1433published inCell Death & DifferentiationQ2943974
P1476titleAMPK couples p73 with p53 in cell fate decision
P478volume21

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cites work (P2860)
Q38266299A balancing act: orchestrating amino-truncated and full-length p73 variants as decisive factors in cancer progression
Q38998413AMPK and Cancer
Q50290367AMPK phosphorylates TP53
Q38764024AMPK β1 reduces tumor progression and improves survival in p53 null mice.
Q60927924AMPK: Regulation of Metabolic Dynamics in the Context of Autophagy
Q36866479Activation of PPARγ/P53 signaling is required for curcumin to induce hepatic stellate cell senescence
Q40452377Activation of p53/miR-34a Tumor Suppressor Axis by Chinese Herbal Formula JP-1 in A549 Lung Adenocarcinoma Cells.
Q58129865Cancer driver mutations in endometriosis: Variations on the major theme of fibrogenesis
Q90600922Context-dependent AMPK activation distinctly regulates TAp73 stability and transcriptional activity
Q26775866DNA repair and aging: the impact of the p53 family
Q93047778Glucose-dependent GPER1 expression modulates tamoxifen-induced IGFBP-1 accumulation
Q37327366Metabolic pathways regulated by TAp73 in response to oxidative stress
Q26774960Neuroblastoma: oncogenic mechanisms and therapeutic exploitation of necroptosis
Q26771603P53 functional abnormality in mesenchymal stem cells promotes osteosarcoma development
Q93148944Role of p53 Family Proteins in Metformin Anti-Cancer Activities
Q38252591Screening for E3-ubiquitin ligase inhibitors: challenges and opportunities
Q37301684Setdb1, a novel interactor of ΔNp63, is involved in breast tumorigenesis
Q36182254TAp73 transcriptionally represses BNIP3 expression.
Q40548355The E3 ligase Itch knockout mice show hyperproliferation and wound healing alteration.
Q33829275Ultraconserved long non-coding RNA uc.63 in breast cancer
Q41842526p73 promotes glioblastoma cell invasion by directly activating POSTN (periostin) expression
Q36545105p73 regulates basal and starvation-induced liver metabolism in vivo

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