Intracellular replication of the well-armed pathogen Burkholderia pseudomallei

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Intracellular replication of the well-armed pathogen Burkholderia pseudomallei is …
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scholarly articleQ13442814

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P356DOI10.1016/J.MIB.2015.11.007
P3181OpenCitations bibliographic resource ID3448248
P698PubMed publication ID26803404
P5875ResearchGate publication ID291419596

P50authorBrendan W WrenQ65559586
P2093author name stringHelen S Atkins
Sam J Willcocks
Carmen C Denman
P2860cites workGenomic plasticity of the causative agent of melioidosis, Burkholderia pseudomalleiQ24564168
From crystal structure to in silico epitope discovery in the Burkholderia pseudomallei flagellar hook-associated protein FlgKQ27697853
The Type VI secretion system spike protein VgrG5 mediates membrane fusion during intercellular spread by pseudomallei group Burkholderia speciesQ28305769
The condition-dependent transcriptional landscape of Burkholderia pseudomalleiQ28533374
Toll-like receptor 2 impairs host defense in gram-negative sepsis caused by Burkholderia pseudomallei (Melioidosis)Q28757205
Dissection of the Burkholderia intracellular life cycle using a photothermal nanobladeQ30502767
Toll-like receptor 4 region genetic variants are associated with susceptibility to melioidosis.Q30527785
The role of NOD2 in murine and human melioidosisQ30560623
Analysis of the prevalence, secretion and function of a cell cycle-inhibiting factor in the melioidosis pathogen Burkholderia pseudomalleiQ31160722
Burkholderia pseudomallei genome plasticity associated with genomic island variationQ33331035
Activation of Toll-like receptors by Burkholderia pseudomalleiQ33358960
Differential intracellular fate of Burkholderia pseudomallei 844 and Burkholderia thailandensis UE5 in human monocyte-derived dendritic cells and macrophagesQ33435686
Global transcriptional profiling of Burkholderia pseudomallei under salt stress reveals differential effects on the Bsa type III secretion systemQ33602104
Type three secretion system-mediated escape of Burkholderia pseudomallei into the host cytosol is critical for the activation of NFκBQ33634322
Identification of Burkholderia mallei and Burkholderia pseudomallei adhesins for human respiratory epithelial cellsQ33709714
A high-content imaging assay for the quantification of the Burkholderia pseudomallei induced multinucleated giant cell (MNGC) phenotype in murine macrophages.Q33828635
The Burkholderia pseudomallei type III secretion system and BopA are required for evasion of LC3-associated phagocytosisQ33849013
Characterization of BPSS1521 (bprD), a regulator of Burkholderia pseudomallei virulence gene expression in the mouse model.Q34027655
Proteomic analysis of the Burkholderia pseudomallei type II secretome reveals hydrolytic enzymes, novel proteins, and the deubiquitinase TssMQ34059012
Actin-Based Motility of Burkholderia thailandensis Requires a Central Acidic Domain of BimA That Recruits and Activates the Cellular Arp2/3 ComplexQ34150670
Superoxide dismutase C is required for intracellular survival and virulence of Burkholderia pseudomalleiQ34191386
Transcriptional profiles of Burkholderia pseudomallei reveal the direct and indirect roles of Sigma E under oxidative stress conditions.Q34246403
Branched-chain fatty acids promote Listeria monocytogenes intracellular infection and virulence.Q34290837
Genetic and transcriptional analysis of the siderophore malleobactin biosynthesis and transport genes in the human pathogen Burkholderia pseudomallei K96243.Q34353807
Characterization and analysis of the Burkholderia pseudomallei BsaN virulence regulonQ34538165
Mechanism and inhibition of the FabI enoyl-ACP reductase from Burkholderia pseudomalleiQ34566539
Identification of Burkholderia pseudomallei genes required for the intracellular life cycle and in vivo virulence.Q34681050
The cluster 1 type VI secretion system is a major virulence determinant in Burkholderia pseudomalleiQ34740016
Interrogation of the Burkholderia pseudomallei genome to address differential virulence among isolates.Q34764795
Mechanisms of membrane fusion: disparate players and common principles.Q34780589
Type 3 secretion system cluster 3 is a critical virulence determinant for lung-specific melioidosisQ34875425
Current molecular models for NADPH oxidase regulation by Rac GTPaseQ34915029
Sequence-defined transposon mutant library of Burkholderia thailandensisQ35032203
Toll-like receptor signaling in airborne Burkholderia thailandensis infectionQ39588062
Migration of dendritic cells facilitates systemic dissemination of Burkholderia pseudomallei.Q39595676
Nucleotide-binding oligomerization domain-containing protein 2 regulates suppressor of cytokine signaling 3 expression in Burkholderia pseudomallei-infected mouse macrophage cell line RAW 264.7.Q39630066
Suppression of host innate immune response by Burkholderia pseudomallei through the virulence factor TssM.Q39723299
Involvement of beta interferon in enhancing inducible nitric oxide synthase production and antimicrobial activity of Burkholderia pseudomallei-infected macrophagesQ39755072
A Burkholderia pseudomallei type III secreted protein, BopE, facilitates bacterial invasion of epithelial cells and exhibits guanine nucleotide exchange factor activityQ39793977
Inactivation of Burkholderia pseudomallei bsaQ results in decreased invasion efficiency and delayed escape of bacteria from endocytic vesiclesQ39957458
Interleukin-8 induction by Burkholderia pseudomallei can occur without Toll-like receptor signaling but requires a functional type III secretion systemQ39991050
Caspase-1 dependent macrophage death induced by Burkholderia pseudomalleiQ40375447
Identification of a bacterial factor required for actin-based motility of Burkholderia pseudomalleiQ40445669
Plasticity of the malleobactin pathway and its impact on siderophore action in human pathogenic bacteriaQ41334964
Intracellular bacteria find the right motionQ41345991
A polar-localized iron-binding protein determines the polar targeting of Burkholderia BimA autotransporter and actin tail formationQ41712159
Deficiency of protease-activated receptor-1 limits bacterial dissemination during severe Gram-negative sepsis (melioidosis).Q42240421
Multinucleated giant cell formation and apoptosis in infected host cells is mediated by Burkholderia pseudomallei type III secretion protein BipB.Q42283500
Induction of protective immunity against Burkholderia pseudomallei using attenuated mutants with defects in the intracellular life cycleQ43838811
Activation of NADPH oxidase is essential, but not sufficient, in controlling intracellular multiplication of Burkholderia pseudomallei in primary human monocytesQ45072986
The pathogenesis of Staphylococcus aureus infection in the diabetic NOD mouseQ46722508
Type III secretion system cluster 3 is required for maximal virulence of Burkholderia pseudomallei in a hamster infection model.Q50094281
Compensatory increase in ahpC gene expression and its role in protecting Burkholderia pseudomallei against reactive nitrogen intermediates.Q52552488
Molecular characterization of putative virulence determinants in Burkholderia pseudomalleiQ59100523
Multiple mechanisms involved in diabetes protection by lipopolysaccharide in non-obese diabetic miceQ87158357
Genome-wide saturation mutagenesis of Burkholderia pseudomallei K96243 predicts essential genes and novel targets for antimicrobial developmentQ35092525
Variable virulence factors in Burkholderia pseudomallei (melioidosis) associated with human diseaseQ35117710
Caspase-1-dependent and -independent cell death pathways in Burkholderia pseudomallei infection of macrophagesQ35120217
Regulation of type VI secretion system during Burkholderia pseudomallei infectionQ35139359
Strategies for Intracellular Survival of Burkholderia pseudomallei.Q35173801
Burkholderia pseudomallei type III secretion system cluster 3 ATPase BsaS, a chemotherapeutic target for small-molecule ATPase inhibitors.Q35187657
Role for the Burkholderia pseudomallei type three secretion system cluster 1 bpscN gene in virulenceQ35191913
Role of inducible nitric oxide synthase and NADPH oxidase in early control of Burkholderia pseudomallei infection in miceQ35217529
Systematic mutagenesis of genes encoding predicted autotransported proteins of Burkholderia pseudomallei identifies factors mediating virulence in mice, net intracellular replication and a novel protein conferring serum resistanceQ35242077
T Cell Immunity to the Alkyl Hydroperoxide Reductase of Burkholderia pseudomallei: A Correlate of Disease Outcome in Acute MelioidosisQ35560710
Development of signature-tagged mutagenesis in Burkholderia pseudomallei to identify genes important in survival and pathogenesisQ35689501
Macroautophagy is essential for killing of intracellular Burkholderia pseudomallei in human neutrophilsQ35871486
Fate of a Burkholderia pseudomallei lipopolysaccharide mutant in the mouse macrophage cell line RAW 264.7: possible role for the O-antigenic polysaccharide moiety of lipopolysaccharide in internalization and intracellular survivalQ35947308
Comprehensive identification of virulence factors required for respiratory melioidosis using Tn-seq mutagenesisQ36245628
Extended loop region of Hcp1 is critical for the assembly and function of type VI secretion system in Burkholderia pseudomalleiQ36294134
Intracellular Mycobacterium tuberculosis exploits host-derived fatty acids to limit metabolic stressQ36666086
Impaired TLR5 functionality is associated with survival in melioidosisQ36713996
Human polymorphonuclear neutrophil responses to Burkholderia pseudomallei in healthy and diabetic subjectsQ37033064
Functional characterization of Burkholderia pseudomallei trimeric autotransportersQ37035962
Less is more: Burkholderia pseudomallei and chronic melioidosisQ37194316
Type II fatty acid synthesis is essential only for malaria parasite late liver stage developmentQ37208067
The Burkholderia pseudomallei enoyl-acyl carrier protein reductase FabI1 is essential for in vivo growth and is the target of a novel chemotherapeutic with efficacyQ37544698
VgrG-5 is a Burkholderia type VI secretion system-exported protein required for multinucleated giant cell formation and virulenceQ37713299
BPSS1504, a cluster 1 type VI secretion gene, is involved in intracellular survival and virulence of Burkholderia pseudomalleiQ37713394
Architecture and assembly of the Type VI secretion system.Q38200408
Virulent Burkholderia species mimic host actin polymerases to drive actin-based motilityQ38888936
Transcriptome analysis of Burkholderia pseudomallei T6SS identifies Hcp1 as a potential serodiagnostic markerQ38917037
Programmed death ligand 1 on Burkholderia pseudomallei-infected human polymorphonuclear neutrophils impairs T cell functionsQ38924981
Stimulation of autophagy suppresses the intracellular survival of Burkholderia pseudomallei in mammalian cell lines.Q38957659
Functional characterizations of effector protein BipC, a type III secretion system protein, in Burkholderia pseudomallei pathogenesis.Q38962209
The serine protease inhibitor Ecotin is required for full virulence of Burkholderia pseudomalleiQ39030833
Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutantsQ39407784
Spermidine acetyltransferase is required to prevent spermidine toxicity at low temperatures in Escherichia coliQ39585712
P407language of work or nameEnglishQ1860
P921main subjectBurkholderia pseudomalleiQ140475
P304page(s)94-103
P577publication date2016-02-01
P1433published inCurrent Opinion in MicrobiologyQ15752444
P1476titleIntracellular replication of the well-armed pathogen Burkholderia pseudomallei
P478volume29

Reverse relations

cites work (P2860)
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Q90243749Human Melioidosis
Q57094969Melioidosis
Q61699558Melioidosis
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Q40569998Trehalose metabolism: A sweet spot for Burkholderia pseudomallei virulence
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