| scholarly article | Q13442814 |
| review article | Q7318358 |
| P356 | DOI | 10.14348/MOLCELLS.2015.0294 |
| P8608 | Fatcat ID | release_vwticemttncfhdajhvd6k5d2za |
| P932 | PMC publication ID | 4673406 |
| P698 | PubMed publication ID | 26552488 |
| P5875 | ResearchGate publication ID | 283687620 |
| P2093 | author name string | Jungeun An | |
| Myunggon Ko | |||
| Jae-A Han | |||
| P2860 | cites work | Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations | Q42141882 |
| 5-formylcytosine and 5-carboxylcytosine reduce the rate and substrate specificity of RNA polymerase II transcription. | Q42267251 | ||
| Somatic RHOA mutation in angioimmunoblastic T cell lymphoma. | Q42808195 | ||
| TET1 is a DNA-binding protein that modulates DNA methylation and gene transcription via hydroxylation of 5-methylcytosine | Q42811756 | ||
| Regulation of TET protein stability by calpains. | Q42998566 | ||
| 5-Formylcytosine alters the structure of the DNA double helix | Q43096431 | ||
| Ascorbic acid enhances Tet-mediated 5-methylcytosine oxidation and promotes DNA demethylation in mammals | Q43929444 | ||
| Methylation of TET2, CBL and CEBPA in Ph-negative myeloproliferative neoplasms | Q44705028 | ||
| Association of common gene variants in the WNT/β-catenin pathway with colon cancer recurrence. | Q46014740 | ||
| TET2 is essential for survival and hematopoietic stem cell homeostasis | Q47951540 | ||
| Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives | Q48151931 | ||
| TET2 promoter methylation in low-grade diffuse gliomas lacking IDH1/2 mutations | Q49147715 | ||
| Tet2-mutated myeloid progenitors possess aberrant in vitro self-renewal capacity. | Q53054214 | ||
| Decreased expression of CXXC4 promotes a malignant phenotype in renal cell carcinoma by activating Wnt signaling. | Q53316745 | ||
| TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23). | Q55036452 | ||
| Clonal architecture of chronic myelomonocytic leukemias | Q57219718 | ||
| Mechanism and Stem-Cell Activity of 5-Carboxycytosine Decarboxylation Determined by Isotope Tracing | Q57376743 | ||
| Common 4q24 deletion in four cases of hematopoietic malignancy: early stem cell involvement? | Q81791345 | ||
| TET2 and DNMT3A mutations in human T-cell lymphoma | Q83175924 | ||
| Genomic 5-hydroxymethylcytosine levels correlate with TET2 mutations and a distinct global gene expression pattern in secondary acute myeloid leukemia | Q84228011 | ||
| ASXL1 mutation is associated with poor prognosis and acute transformation in chronic myelomonocytic leukaemia | Q85109789 | ||
| Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids | Q22064352 | ||
| Inhibition of the Wnt signaling pathway by Idax, a novel Dvl-binding protein | Q24290612 | ||
| Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain | Q24299862 | ||
| Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA | Q24305161 | ||
| Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2 | Q24306181 | ||
| Crystal structure of TET2-DNA complex: insight into TET-mediated 5mC oxidation | Q24311603 | ||
| Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1 | Q24316558 | ||
| Cancer-associated IDH1 mutations produce 2-hydroxyglutarate | Q24320239 | ||
| Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites | Q24328865 | ||
| UHRF1 plays a role in maintaining DNA methylation in mammalian cells | Q24336152 | ||
| The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate | Q24605258 | ||
| Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine | Q24614582 | ||
| Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA | Q24632387 | ||
| Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases | Q24632807 | ||
| An integrated genomic analysis of human glioblastoma multiforme | Q24648860 | ||
| IDH1 and IDH2 mutations in gliomas | Q24648948 | ||
| Connections between TET proteins and aberrant DNA modification in cancer | Q26865671 | ||
| Mechanism and function of oxidative reversal of DNA and RNA methylation | Q27002361 | ||
| Loss of function of TET2 cooperates with constitutively active KIT in murine and human models of mastocytosis | Q27334940 | ||
| The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix | Q27651993 | ||
| Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1 | Q27651995 | ||
| Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism | Q27651997 | ||
| Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development | Q27675385 | ||
| IDH1 mutations in patients with myelodysplastic syndromes are associated with an unfavorable prognosis. | Q27851565 | ||
| Acquired mutations in the genes encoding IDH1 and IDH2 both are recurrent aberrations in acute myeloid leukemia: prevalence and prognostic value | Q27851569 | ||
| IDH2 mutations are frequent in angioimmunoblastic T-cell lymphoma | Q27851701 | ||
| Prognostic relevance of integrated genetic profiling in acute myeloid leukemia | Q27851726 | ||
| Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence | Q28117086 | ||
| DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia | Q28253465 | ||
| WT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation | Q28255707 | ||
| TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis | Q28507642 | ||
| Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation | Q28508217 | ||
| Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice | Q28511594 | ||
| The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA | Q28589108 | ||
| Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies | Q28591763 | ||
| The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing | Q28749183 | ||
| Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation | Q29615366 | ||
| DNA methylation landscapes: provocative insights from epigenomics | Q29617144 | ||
| Mutation in TET2 in myeloid cancers | Q29619292 | ||
| Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo | Q30413034 | ||
| SRSF2 mutations in 275 cases with chronic myelomonocytic leukemia (CMML) | Q30420638 | ||
| Recurrent TET2 mutations in peripheral T-cell lymphomas correlate with TFH-like features and adverse clinical parameters | Q33402136 | ||
| SRSF2-p95 hotspot mutation is highly associated with advanced forms of mastocytosis and mutations in epigenetic regulator genes | Q33558793 | ||
| A screen for hydroxymethylcytosine and formylcytosine binding proteins suggests functions in transcription and chromatin regulation | Q33585142 | ||
| 5-Formylcytosine can be a stable DNA modification in mammals | Q33840288 | ||
| Natural history of eukaryotic DNA methylation systems | Q33878008 | ||
| Evaluation of allelic strength of human TET2 mutations and cooperation between Tet2 knockdown and oncogenic Nras mutation | Q33934784 | ||
| LCX, leukemia-associated protein with a CXXC domain, is fused to MLL in acute myeloid leukemia with trilineage dysplasia having t(10;11)(q22;q23). | Q33960274 | ||
| Dnmt3a is essential for hematopoietic stem cell differentiation | Q34237926 | ||
| Role of Tet proteins in enhancer activity and telomere elongation | Q34271341 | ||
| Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis | Q34301317 | ||
| The oncogenic microRNA miR-22 targets the TET2 tumor suppressor to promote hematopoietic stem cell self-renewal and transformation | Q34355585 | ||
| Single nucleotide polymorphism array lesions, TET2, DNMT3A, ASXL1 and CBL mutations are present in systemic mastocytosis. | Q34384728 | ||
| Activation-induced cytidine deaminase alters the subcellular localization of Tet family proteins | Q34427913 | ||
| Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1. | Q34574880 | ||
| A targeted mutational landscape of angioimmunoblastic T-cell lymphoma. | Q34663596 | ||
| Acquired mutations in TET2 are common in myelodysplastic syndromes | Q34984094 | ||
| CRL4(VprBP) E3 ligase promotes monoubiquitylation and chromatin binding of TET dioxygenases | Q35007645 | ||
| Proto-oncogenic role of mutant IDH2 in leukemia initiation and maintenance | Q35234477 | ||
| 5-Hydroxymethylcytosine is a predominantly stable DNA modification. | Q35244114 | ||
| Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors | Q35797589 | ||
| Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex | Q35907869 | ||
| TET1 is a tumor suppressor of hematopoietic malignancy | Q35983746 | ||
| Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation | Q36008141 | ||
| TET proteins and 5-methylcytosine oxidation in hematological cancers | Q36197509 | ||
| The mammalian de novo DNA methyltransferases DNMT3A and DNMT3B are also DNA 5-hydroxymethylcytosine dehydroxymethylases | Q36286073 | ||
| Frequent TET2 mutations in systemic mastocytosis: clinical, KITD816V and FIP1L1-PDGFRA correlates | Q36303456 | ||
| Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6 | Q36420383 | ||
| Selective excision of 5-carboxylcytosine by a thymine DNA glycosylase mutant. | Q36674636 | ||
| Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX. | Q36815200 | ||
| HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis. | Q36932231 | ||
| TET1 plays an essential oncogenic role in MLL-rearranged leukemia | Q37031819 | ||
| MicroRNA-antagonism regulates breast cancer stemness and metastasis via TET-family-dependent chromatin remodeling. | Q37156452 | ||
| TETonic shift: biological roles of TET proteins in DNA demethylation and transcription | Q37244379 | ||
| MicroRNA-26a targets ten eleven translocation enzymes and is regulated during pancreatic cell differentiation | Q37276461 | ||
| An extensive network of TET2-targeting MicroRNAs regulates malignant hematopoiesis | Q37327706 | ||
| Clinical and biological implications of driver mutations in myelodysplastic syndromes | Q37334716 | ||
| Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells | Q37486341 | ||
| Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells | Q37543786 | ||
| Landscape of genetic lesions in 944 patients with myelodysplastic syndromes | Q37571585 | ||
| Mammalian cytosine methylation at a glance. | Q37573260 | ||
| Differential regulation of the ten-eleven translocation (TET) family of dioxygenases by O-linked β-N-acetylglucosamine transferase (OGT). | Q37608526 | ||
| Reversing DNA methylation: mechanisms, genomics, and biological functions | Q37609689 | ||
| Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomas | Q37658327 | ||
| IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics | Q37734751 | ||
| 5mC oxidation by Tet2 modulates enhancer activity and timing of transcriptome reprogramming during differentiation | Q38952550 | ||
| Ascorbate induces ten-eleven translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine | Q40601043 | ||
| Tet2 disruption leads to enhanced self-renewal and altered differentiation of fetal liver hematopoietic stem cells | Q41200952 | ||
| Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders | Q41775948 | ||
| Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia | Q41818692 | ||
| Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells | Q41960997 | ||
| P433 | issue | 11 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | regulation of gene expression | Q411391 |
| DNA methylation | Q874745 | ||
| dysplasia | Q1128996 | ||
| cell biology | Q7141 | ||
| DNA-binding protein | Q2252764 | ||
| lymphoid leukemia | Q6708277 | ||
| myeloid leukemia | Q11688946 | ||
| enzyme | Q8047 | ||
| genetic epigenesis | Q64443099 | ||
| P304 | page(s) | 925-35 | |
| P577 | publication date | 2015-11-01 | |
| P1433 | published in | Molecules and Cells | Q12623193 |
| P1476 | title | Functions of TET Proteins in Hematopoietic Transformation | |
| P478 | volume | 38 |
| Q37575781 | DNA Demethylation of the Foxp3 Enhancer Is Maintained through Modulation of Ten-Eleven-Translocation and DNA Methyltransferases |
| Q92702483 | Epigenetic Dysregulation at the Crossroad of Women's Cancer |
| Q47134267 | Gene-body hypermethylation controlled cryptic promoter and miR26A1-dependent EZH2 regulation of TET1 gene activity in chronic lymphocytic leukemia |
| Q60919331 | Global distribution of DNA hydroxymethylation and DNA methylation in chronic lymphocytic leukemia |
| Q53831450 | Inhibition of DNA methyltransferase leads to increased genomic 5-hydroxymethylcytosine levels in hematopoietic cells. |
| Q47108992 | Modeling Myeloid Malignancies Using Zebrafish. |
| Q39268149 | TET family dioxygenases and DNA demethylation in stem cells and cancers |
| Q33751122 | Tumor necrosis factor-α decreases EC-SOD expression through DNA methylation |
Search more.