The Role of Autophagy in Lupus Nephritis

scientific article

The Role of Autophagy in Lupus Nephritis is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.3390/IJMS161025154
P932PMC publication ID4632796
P698PubMed publication ID26506346
P5875ResearchGate publication ID283295025

P2093author name stringLinlin Wang
Helen Ka Wai Law
P2860cites workActivation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destructionQ24303900
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other lociQ24306903
Impairment of neutrophil extracellular trap degradation is associated with lupus nephritisQ24606320
A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosusQ24629130
Apolipoprotein L1, a novel Bcl-2 homology domain 3-only lipid-binding protein, induces autophagic cell deathQ24652950
Autophagy in the Pathogenesis of DiseaseQ27860558
Autophagy fights disease through cellular self-digestionQ27860902
mTOR activation is a biomarker and a central pathway to autoimmune disorders, cancer, obesity, and agingQ28081442
Autophagy is activated in systemic lupus erythematosus and required for plasmablast developmentQ28656075
Low dose rapamycin exacerbates autoimmune experimental uveitisQ28730115
Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in AsiansQ28943338
Autophagy: process and functionQ29547296
Regulation mechanisms and signaling pathways of autophagyQ29547416
Development by self-digestion: molecular mechanisms and biological functions of autophagyQ29547880
Autophagy-dependent viral recognition by plasmacytoid dendritic cellsQ29614177
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta productionQ29614472
The role of autophagy in neurodegenerative diseaseQ29614834
Autophagy in health and disease: a double-edged swordQ29618103
Early events in lupus humoral autoimmunity suggest initiation through molecular mimicryQ33364289
Aberrant Epstein-Barr viral infection in systemic lupus erythematosusQ33655378
Nuclear location of an endogenously expressed antigen, EBNA1, restricts access to macroautophagy and the range of CD4 epitope display.Q33719767
Autophagy promotes MHC class II presentation of peptides from intracellular source proteinsQ33841180
The role of PI3P phosphatases in the regulation of autophagyQ33914205
Microautophagy in mammalian cells: revisiting a 40-year-old conundrumQ34190348
Brief Report: identification of MTMR3 as a novel susceptibility gene for lupus nephritis in northern Han Chinese by shared-gene analysis with IgA nephropathy.Q34270321
HSC70 blockade by the therapeutic peptide P140 affects autophagic processes and endogenous MHCII presentation in murine lupus.Q34625909
Exposure to maternal smoking and incident SLE in a prospective cohort studyQ35088861
Chaperone-mediated autophagyQ35107699
Trehalose, an mTOR independent autophagy inducer, alleviates human podocyte injury after puromycin aminonucleoside treatment.Q35439721
UV Light Potentiates STING (Stimulator of Interferon Genes)-dependent Innate Immune Signaling through Deregulation of ULK1 (Unc51-like Kinase 1)Q35583137
Clinical Features and Histology of Apolipoprotein L1-Associated Nephropathy in the FSGS Clinical TrialQ35658566
The expression of EBV-encoded LMP1 in young patients with lupus nephritis.Q35792180
Knockdown of autophagy enhances the innate immune response in hepatitis C virus-infected hepatocytesQ35910776
The PI3K/Akt/mTOR pathway is activated in murine lupus nephritis and downregulated by rapamycin.Q51547435
DNase 1 activity in patients with systemic lupus erythematosus: relationship with epidemiological, clinical, immunological and therapeutical features.Q51752532
The pathogenesis of lupus nephritis.Q51868414
Plasma cells require autophagy for sustainable immunoglobulin production.Q53122740
Systemic lupus erythematosus.Q53202066
Epstein-Barr virus and systemic lupus erythematosusQ58908905
Neutrophil Extracellular Traps That Are Not Degraded in Systemic Lupus Erythematosus Activate Complement Exacerbating the DiseaseQ60250015
Systemic lupus erythematosus and the neutrophilQ84816491
The Atg5 Atg12 conjugate associates with innate antiviral immune responsesQ35956883
Endothelial cell and podocyte autophagy synergistically protect from diabetes-induced glomerulosclerosis.Q36111664
Macroautophagy is deregulated in murine and human lupus T lymphocytesQ36194783
Autophagy in immunity: implications in etiology of autoimmune/autoinflammatory diseasesQ36235457
Ultraviolet light and cutaneous lupusQ36676995
ATG5 regulates plasma cell differentiationQ36769690
Innate and adaptive immunity through autophagyQ36896712
Unveiling the roles of autophagy in innate and adaptive immunityQ36927499
Pivotal role for the mTOR pathway in the formation of neutrophil extracellular traps via regulation of autophagyQ37093598
Mapping similarities in mTOR pathway perturbations in mouse lupus nephritis models and human lupus nephritisQ37129534
The expression of renal Epstein-Barr virus markers in patients with lupus nephritisQ37710075
End-stage renal disease in African Americans with lupus nephritis is associated with APOL1Q37728822
Monocyte and Macrophage Abnormalities in Systemic Lupus ErythematosusQ37777065
Hydroxychloroquine: from malaria to autoimmunityQ37827403
Autophagy and cytokinesQ37926024
Autophagy and the immune systemQ37997062
Lupus nephritis and end-stage kidney diseaseQ38078211
Emerging view of autophagy in systemic lupus erythematosus.Q38189443
Autophagy in antimicrobial immunityQ38207186
Treatment of severe lupus nephritis: the new horizon.Q38271125
Resetting the autoreactive immune system with a therapeutic peptide in lupusQ38388415
Apolipoprotein L1 risk variants associate with systemic lupus erythematosus-associated collapsing glomerulopathyQ38397636
Blockade of macrophage autophagy ameliorates activated lymphocytes-derived DNA induced murine lupus possibly via inhibition of proinflammatory cytokine productionQ38963312
Glucocorticoids downregulate Fyn and inhibit IP3-mediated calcium signaling to promote autophagy in T lymphocytesQ39660061
Modulation of local PtdIns3P levels by the PI phosphatase MTMR3 regulates constitutive autophagyQ39754404
Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging miceQ39812158
The latent membrane protein 1 oncogene modifies B-cell physiology by regulating autophagyQ40044863
Apolipoprotein L1-associated nephropathy and the future of renal diagnosticsQ42943112
Raised antibody titres to E.B. virus in systemic lupus erythematosusQ45059909
Nephrotoxicity of rapamycin: an emerging problem in clinical medicineQ45211831
Systemic lupus erythematosus in adults is associated with previous Epstein-Barr virus exposureQ45737398
Epstein-Barr virus infection may be an environmental risk factor for systemic lupus erythematosus in children and teenagersQ45747821
Rapamycin attenuates the severity of established nephritis in lupus-prone NZB/W F1 mice.Q46619969
Genetic association of PRDM1-ATG5 intergenic region and autophagy with systemic lupus erythematosus in a Chinese populationQ46869773
Sun-induced life-threatening lupus nephritisQ46982885
Proliferation signal inhibitors in the treatment of lupus nephritis: preliminary experience.Q47361768
T cell recognition and therapeutic effect of a phosphorylated synthetic peptide of the 70K snRNP protein administered in MR/lpr mice.Q47565748
P275copyright licenseCreative Commons AttributionQ6905323
P6216copyright statuscopyrightedQ50423863
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectautophagyQ288322
lupus nephritisQ1621830
autoantigenQ4072475
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)25154-67
P577publication date2015-10-22
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleThe Role of Autophagy in Lupus Nephritis
P478volume16

Reverse relations

cites work (P2860)
Q93047803Accelerated and Severe Lupus Nephritis Benefits From M1, an Active Metabolite of Ginsenoside, by Regulating NLRP3 Inflammasome and T Cell Functions in Mice
Q61814941Autophagy in Chronic Kidney Diseases
Q93272821Autophagy-mediated regulation of neutrophils and clinical applications
Q38926368Cell death in the pathogenesis of systemic lupus erythematosus and lupus nephritis
Q39226501Emerging Roles of IL-33/ST2 Axis in Renal Diseases.
Q90482011Exacerbating lupus nephritis following BPA exposure is associated with abnormal autophagy in MRL/lpr mice
Q91887909High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus
Q39031764Hydroxychloroquine in systemic lupus erythematosus (SLE).
Q89241556Increased Macroautophagy in Interferon-Gamma-Producing T Cells from Patients with Newly Diagnosed Systemic Lupus Erythematosus
Q95320598Inhibition of soluble epoxide hydrolase attenuates renal tubular mitochondrial dysfunction and ER stress by restoring autophagic flux in diabetic nephropathy
Q38634529Lysosomal targeting strategies for design and delivery of bioactive for therapeutic interventions
Q55455268More Than Skin Deep: Autophagy Is Vital for Skin Barrier Function.
Q92222878Programmed Cell Death Pathways in the Pathogenesis of Systemic Lupus Erythematosus
Q39198894Regulatory effects of autophagy on spermatogenesis
Q42282538Role of autophagy in cell-penetrating peptide transfection model.
Q92956352The Role of NETosis in Systemic Lupus Erythematosus
Q39100146UCH-L1 Expressed by Podocytes: a Potentially Therapeutic Target for Lupus Nephritis?
Q60910374Vitamin D protects podocytes from autoantibodies induced injury in lupus nephritis by reducing aberrant autophagy

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