Hydroxychloroquine: from malaria to autoimmunity

scientific article published on April 2012

Hydroxychloroquine: from malaria to autoimmunity is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1007/S12016-010-8243-X
P932PMC publication ID7091063
P698PubMed publication ID21221847

P50authorYehuda ShoenfeldQ1515807
Shaye KivityQ73295123
Pnina LangevitzQ73421809
Ilan Ben-ZviQ37829259
P2860cites workAntimalarial Drug ToxicityQ22061779
Drugs for discoid lupus erythematosusQ24240456
Chloroquine is a potent inhibitor of SARS coronavirus infection and spreadQ24815979
Cholesterol-lowering effect of hydroxychloroquine in patients with rheumatic disease: reversal of deleterious effects of steroids on lipidsQ41943371
Hydroxychloroquine-induced toxic myopathy causing respiratory failureQ41943600
Hydroxychloroquine in decompensated, treatment-refractory noninsulin-dependent diabetes mellitus. A new job for an old drug?Q41943988
Mode of action of hydroxychloroquine in RA-evidence of an inhibitory effect on toll-like receptor signalingQ41944676
Granulomatous infiltration of the talus and abnormal vitamin D and calcium metabolism in a patient with sarcoidosis: successful treatment with hydroxychloroquineQ41945060
Effect of a malaria suppression program on the incidence of African Burkitt's lymphomaQ41945980
Hydroxychloroquine-induced cardiotoxicity in a 39-year-old woman with systemic lupus erythematosus and systolic dysfunctionQ41946807
Sensory neuronopathy with Ro antibodies: response to combination immunosuppressionQ43136539
Ocular toxicity and antenatal exposure to chloroquine or hydroxychloroquine for rheumatic diseasesQ43743058
Treatment of generalized granuloma annulare with hydroxychloroquineQ46641262
Quinines--past and presentQ47842867
Hydroxychloroquine reverses platelet activation induced by human IgG antiphospholipid antibodies.Q50196335
Oral mucosal hyperpigmentation secondary to antimalarial drug therapy.Q50510120
Respiratory function in systemic lupus erythematosus: relation with activity and severity.Q51031044
The history of antimalarials.Q53622368
Thrombosis and systemic lupus erythematosus: the Hopkins Lupus Cohort perspectiveQ71500994
Treatment of lupus erythematosus with mepacrineQ75834093
Ocular toxicity of hydroxychloroquineQ81141186
A cross-sectional study of clinical thrombotic risk factors and preventive treatments in antiphospholipid syndromeQ28193536
Eosinophilic fasciitis: clinical spectrum and therapeutic response in 52 casesQ28293575
Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesisQ30480882
The anti-HIV-1 activity of chloroquineQ31884593
Early induction of apoptosis in B-chronic lymphocytic leukaemia cells by hydroxychloroquine: activation of caspase-3 and no protection by survival factorsQ31893630
Hydroxychloroquine in lupus pregnancyQ33373145
Effect of medication on microvascular vasodilatation in patients with systemic lupus erythematosusQ33609077
Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cellsQ33632727
Hydroxychloroquine protects the annexin A5 anticoagulant shield from disruption by antiphospholipid antibodies: evidence for a novel effect for an old antimalarial drugQ33747286
Effects of chloroquine on viral infections: an old drug against today's diseases?Q33973620
Adding chloroquine to conventional treatment for glioblastoma multiforme: a randomized, double-blind, placebo-controlled trialQ33993957
New concepts in antimalarial use and mode of action in dermatologyQ34007922
Effect of chloroquine on insulin and glucose homoeostasis in normal subjects and patients with non-insulin-dependent diabetes mellitusQ34068803
Changes in glycosylated hemoglobin after initiation of hydroxychloroquine or methotrexate treatment in diabetes patients with rheumatic diseasesQ34354276
Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agentsQ34556950
Hydroxychloroquine and risk of diabetes in patients with rheumatoid arthritisQ34648366
The history of lupus erythematosus. From Hippocrates to OslerQ34684696
Effect of disease modifying agents on the lipid profiles of patients with rheumatoid arthritisQ35547305
Safety of hydroxychloroquine in pregnant patients with connective tissue diseases. Review of the literatureQ36049718
Decrease in macrophage antigen catabolism caused by ammonia and chloroquine is associated with inhibition of antigen presentation to T cellsQ36275163
Hydroxychloroquine and glycemia in women with rheumatoid arthritis and systemic lupus erythematosusQ36277899
Cardiomyopathy related to antimalarial therapy with illustrative case reportQ36521126
Evaluation of the risk of anti-SSA/Ro-SSB/La antibody-associated cardiac manifestations of neonatal lupus in fetuses of mothers with systemic lupus erythematosus exposed to hydroxychloroquineQ36672583
Hydroxychloroquine directly reduces the binding of antiphospholipid antibody-beta2-glycoprotein I complexes to phospholipid bilayersQ36843689
Chloroquine ototoxicityQ36861541
Recycling of chloroquine and its hydroxyl analogue to face bacterial, fungal and viral infections in the 21st centuryQ36880738
Insights into atherosclerosis therapy in antiphospholipid syndromeQ36984674
Antiviral activity of chloroquine against human coronavirus OC43 infection in newborn miceQ37274730
Chloroquine and its analogs: a new promise of an old drug for effective and safe cancer therapiesQ37616407
The protective effect of antimalarial drugs on thrombovascular events in systemic lupus erythematosusQ38446538
Chloroquine, quinine, procaine, quinidine, tricyclic antidepressants, and methylxanthines as prostaglandin agonists and antagonistsQ39409324
Hydroxychloroquine sulfate (Plaquenil) improves oral lichen planus: An open trialQ39494741
Hydroxychloroquine, chloroquine, and all-trans retinoic acid regulate growth, survival, and histone acetylation in breast cancer cellsQ39827707
Chloroquine inhibits colon cancer cell growth in vitro and tumor growth in vivo via induction of apoptosisQ39887289
Cell growth inhibition, G2/M cell cycle arrest, and apoptosis induced by chloroquine in human breast cancer cell line Bcap-37.Q39904465
The efficacy and selectivity of tumor cell killing by Akt inhibitors are substantially increased by chloroquineQ39952133
Glucose-6-phosphate dehydrogenase deficiency: mechanisms of drug-induced hemolysisQ40002985
Chloroquine inhibits cell growth and induces cell death in A549 lung cancer cellsQ40329437
Kikuchi-Fujimoto disease: an amazing response to hydroxychloroquineQ40353377
Anti-HIV effects of chloroquine: inhibition of viral particle glycosylation and synergism with protease inhibitors.Q40568140
Hydroxychloroquine inhibits calcium signals in T cells: a new mechanism to explain its immunomodulatory properties.Q40877489
The effects of chloroquine on serum 1,25-dihydroxyvitamin D and calcium metabolism in sarcoidosisQ41473819
The lysosomotropic amines, chloroquine and hydroxychloroquine: a potentially novel therapy for graft-versus-host diseaseQ41475460
Inhibition of human immunodeficiency virus type 1 replication by hydroxychloroquine in T cells and monocytesQ41581307
Palindromic rheumatism: a response to chloroquineQ41887232
Hydroxychloroquine, hydroxyurea and didanosine as initial therapy for HIV-infected patients with low viral load: safety, efficacy and resistance profile after 144 weeksQ41912825
Kikuchi-Fujimoto disease: hydroxychloroquine as a treatmentQ41913103
Follow-up of infants exposed to hydroxychloroquine given to mothers during pregnancy and lactationQ41913288
In vitro inhibition of severe acute respiratory syndrome coronavirus by chloroquineQ41913526
Chloroquine neuromyotoxicity. Clinical and pathologic perspectiveQ41913997
Hydroxychloroquine in polymorphic light eruption: a controlled trial with drug and visual sensitivity monitoringQ41914026
Hydroxychloroquine for the prevention of acute graft-versus-host disease after unrelated donor transplantationQ41914903
Effects of antimalarial drugs on phospholipase A and lysophospholipase activities in plasma membrane, mitochondrial, microsomal and cytosolic subcellular fractions of rat liverQ41916861
Control of mammary tumor cell growth in vitro by novel cell differentiation and apoptosis agentsQ41916902
Hydroxychloroquine-induced apoptosis of chronic lymphocytic leukemia involves activation of caspase-3 and modulation of Bcl-2/bax/ratioQ41917134
Protective effect of hydroxychloroquine in systemic lupus erythematosus. Prospective long-term study of an Israeli cohortQ41917167
Evidence of transplacental passage of hydroxychloroquine in humansQ41917690
The effectiveness of hydroxychloroquine in patients with type 2 diabetes mellitus who are refractory to sulfonylureas--a randomized trialQ41917902
In Vivo Chloroquine-induced Inhibition of Insulin Degradation in a Diabetic Patient with Severe Insulin ResistanceQ41918190
Low-dose oral chloroquine in the treatment of porphyria cutanea tardaQ41918263
Cutaneous lesions of dermatomyositis are improved by hydroxychloroquineQ41919421
Hydroxychloroquine has no significant effect on lipids and apolipoproteins in Chinese systemic lupus erythematosus patients with mild or inactive disease.Q41921127
Skeletal sarcoidosis: successful treatment with hydroxychloroquine.Q41921137
Inhibition of insulin metabolism by hydroxychloroquine and its enantiomers in cytosolic fraction of liver homogenates from healthy and diabetic ratsQ41924532
The cholesterol lowering effect of antimalarial drugs is enhanced in patients with lupus taking corticosteroid drugs.Q41924668
Hypoglycemia induced by hydroxychloroquine in a type II diabetic treated for polyarthritis.Q41924789
A long-term study of hydroxychloroquine withdrawal on exacerbations in systemic lupus erythematosus. The Canadian Hydroxychloroquine Study GroupQ41926859
Hydroxychloroquine reverses thrombogenic properties of antiphospholipid antibodies in miceQ41927420
Lupus panniculitis treated by a combination therapy of hydroxychloroquine and quinacrineQ41927634
Hydroxychloroquine in prophylaxis of pulmonary embolism following hip arthroplastyQ41927753
Treatment of primary Sjögren's syndrome with hydroxychloroquine: a retrospective, open-label study.Q41930645
Chloroquine inhibits stimulated platelets at the arachidonic acid pathwayQ41933340
Low-dose oral chloroquine in patients with porphyria cutanea tarda and low-moderate iron overloadQ41935315
Rates and predictors of hydroxychloroquine retinal toxicity in patients with rheumatoid arthritis and systemic lupus erythematosusQ41935707
The lysosomotropic agent, hydroxychloroquine, delivered in a biodegradable nanoparticle system, overcomes drug resistance of B-chronic lymphocytic leukemia cells in vitroQ41936477
Hydroxychloroquine for subglottic stenosis: a novel therapy in the battle for air.Q41936567
Hydroxychloroquine compared with placebo in rheumatoid arthritis. A randomized controlled trialQ41936586
Effect of chloroquine phosphate treatment on serum MMP-9 and TIMP-1 levels in patients with systemic lupus erythematosusQ41936831
Hydroxychloroquine-induced myopathyQ41936886
Selective regulation of cytokine secretion by hydroxychloroquine: inhibition of interleukin 1 alpha (IL-1-alpha) and IL-6 in human monocytes and T cells.Q41937744
The lipid, lipoprotein, and apolipoprotein effects of hydroxychloroquine in patients with systemic lupus erythematosus.Q41937905
Risk factors for thrombosis and primary thrombosis prevention in patients with systemic lupus erythematosus with or without antiphospholipid antibodies.Q41939439
Growth inhibitory and differentiation effects of chloroquine and its analogue on human leukemic cells potentiate fetal hemoglobin production by targeting the polyamine pathwayQ41939577
Immunologic concepts of light reactions in lupus erythematosus and polymorphous light eruptions. I. The mechanism of action of hydroxychloroquineQ41941168
Mode of action of chloroquine in patients with non-insulin-dependent diabetes mellitusQ41941938
Pregnancy outcome following first trimester exposure to chloroquineQ41942091
Vascular elasticity of systemic lupus erythematosus patients is associated with steroids and hydroxychloroquine treatmentQ41942164
A randomized double-blind trial of hydroxychloroquine for the prevention of chronic graft-versus-host disease after allogeneic peripheral blood stem cell transplantation.Q41942186
SPECTROPHOTOMETRIC STUDIES OF THE INTERACTION OF CHLOROQUINE WITH DEOXYRIBONUCLEIC ACIDQ41942706
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectmalariaQ12156
hydroxychloroquineQ421094
antimalarialQ521616
anti-inflammatory agentQ581996
P304page(s)145-153
P577publication date2012-04-01
P1433published inClinical Reviews in Allergy & ImmunologyQ1932354
P1476titleHydroxychloroquine: from malaria to autoimmunity
P478volume42

Reverse relations

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