Activation of the alternative NFκB pathway improves disease symptoms in a model of Sjogren's syndrome

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Activation of the alternative NFκB pathway improves disease symptoms in a model of Sjogren's syndrome is …
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scholarly articleQ13442814

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P819ADS bibcode2011PLoSO...628727G
P356DOI10.1371/JOURNAL.PONE.0028727
P932PMC publication ID3235165
P698PubMed publication ID22174879
P5875ResearchGate publication ID51884837

P50authorAdi Gilboa-GeffenQ56754536
Geula HaninQ38590342
P2093author name stringHermona Soreq
Naomi Melamed-Book
Maureen Rischmueller
Susan Lester
David S Greenberg
Yochai Wolf
Estelle R Bennett
Marjorie Pick
P2860cites workAcetylcholinesterase--new roles for an old actorQ24291075
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Acetylcholine-evoked calcium mobilization and ion channel activation in human labial gland acinar cells from patients with primary Sjögren's syndromeQ28344891
IkappaB kinase-alpha is critical for interferon-alpha production induced by Toll-like receptors 7 and 9Q28507728
The two NF-kappaB activation pathways and their role in innate and adaptive immunityQ29614355
Regulation and function of NF-kappaB transcription factors in the immune systemQ29616427
Serum cholinesterase activities distinguish between stroke patients and controls and predict 12-month mortalityQ33959166
TLR signalling augments macrophage bactericidal activity through mitochondrial ROS.Q34180844
IDO and regulatory T cells: a role for reverse signalling and non-canonical NF-kappaB activationQ34674495
Hydroxychloroquine treatment for primary Sjögren's syndrome: its effect on salivary and serum inflammatory markersQ35548532
The lymphocytic cholinergic system and its contribution to the regulation of immune activityQ35599803
Functions of NF-kappaB1 and NF-kappaB2 in immune cell biologyQ35815962
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Changes in readthrough acetylcholinesterase expression modulate amyloid-beta pathology.Q53290834
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IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammationQ59054264
Tryptophan catabolism generates autoimmune-preventive regulatory T cellsQ60494045
Inhibitory effects of muscarinic receptor autoantibodies on parasympathetic neurotransmission in Sjögren's syndromeQ74024000
Essential role of IkappaB kinase alpha in thymic organogenesis required for the establishment of self-toleranceQ82878815
Antimuscarinic antibodies in primary Sjogren's syndrome reversibly inhibit the mechanism of fluid secretion by human submandibular salivary acinar cellsQ83008486
Plasmacytoid DCs and T(reg) cells: casual acquaintance or monogamous relationship?Q83820549
Regulatory T-cell physiology and application to treat autoimmunityQ36563537
Mechanisms of Disease: primary Sjögren's syndrome and the type I interferon systemQ36577483
The alternative NF-kappaB pathway from biochemistry to biology: pitfalls and promises for future drug developmentQ36592804
Opposing effects of Toll-like receptor stimulation induce autoimmunity or toleranceQ36695984
Usefulness of mouse models to study the pathogenesis of Sjögren's syndromeQ36852657
TLR7/9 antagonists as therapeutics for immune-mediated inflammatory disordersQ37066753
Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and autoimmune diseases.Q37222231
Acetylcholinesterase/paraoxonase genotype and expression predict anxiety scores in Health, Risk Factors, Exercise Training, and Genetics studyQ37681855
Autoimmune response and target autoantigens in Sjogren's syndrome.Q37772540
Hydroxychloroquine: from malaria to autoimmunityQ37827403
Ligand-induced conformational changes allosterically activate Toll-like receptor 9.Q38300769
Advanced microarray analysis highlights modified neuro-immune signaling in nucleated blood cells from Parkinson's disease patientsQ38512916
NF kappa B-inducing kinase deficiency results in the development of a subset of regulatory T cells, which shows a hyperproliferative activity upon glucocorticoid-induced TNF receptor family-related gene stimulationQ40395246
The innervation of salivary glands as revealed by morphological methodsQ40770892
Immune Interferon in the Circulation of Patients with Autoimmune DiseaseQ41643954
Hydroxychloroquine therapy in patients with primary Sjögren's syndrome may improve salivary gland hypofunction by inhibition of glandular cholinesterase.Q41913046
Role of cytokines in the destruction of acinar structure in Sjögren's syndrome salivary glands.Q42444928
IDO mediates TLR9-driven protection from experimental autoimmune diabetes.Q43258639
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)e28727
P577publication date2011-12-09
P1433published inPLOS OneQ564954
P1476titleActivation of the alternative NFκB pathway improves disease symptoms in a model of Sjogren's syndrome
P478volume6

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