Candidate drugs against SARS-CoV-2 and COVID-19

scientific article published on 29 April 2020

Candidate drugs against SARS-CoV-2 and COVID-19 is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1127167840
P356DOI10.1016/J.PHRS.2020.104859
P932PMC publication ID7189851
P698PubMed publication ID32360480

P2093author name stringStefan Laufer
Cord Naujokat
Ariane Sternberg
Dwight L McKee
Ulrike Stange
P2860cites workThe ambiguous base-pairing and high substrate efficiency of T-705 (Favipiravir) Ribofuranosyl 5'-triphosphate towards influenza A virus polymeraseQ21089768
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Inhibition of angiotensin-converting enzyme 2 exacerbates cardiac hypertrophy and fibrosis in Ren-2 hypertensive ratsQ37084921
Baicalin suppresses NLRP3 inflammasome and nuclear factor-kappa B (NF-κB) signaling during Haemophilus parasuis infectionQ37160312
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Arbidol inhibits viral entry by interfering with clathrin-dependent traffickingQ39104403
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In vitro and in vivo activities of anti-influenza virus compound T-705.Q39651429
TACE antagonists blocking ACE2 shedding caused by the spike protein of SARS-CoV are candidate antiviral compoundsQ39765671
Favipiravir (T-705), a broad spectrum inhibitor of viral RNA polymeraseQ40044875
GS-5734 and its parent nucleoside analog inhibit Filo-, Pneumo-, and ParamyxovirusesQ40066603
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The serine protease inhibitor camostat inhibits influenza virus replication and cytokine production in primary cultures of human tracheal epithelial cells.Q41112381
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Anti-malaria drug chloroquine is highly effective in treating avian influenza A H5N1 virus infection in an animal modelQ43194438
Efficacy of camostat mesilate against dyspepsia associated with non-alcoholic mild pancreatic diseaseQ43252092
Safety and antiviral activity at 48 weeks of lopinavir/ritonavir plus nevirapine and 2 nucleoside reverse-transcriptase inhibitors in human immunodeficiency virus type 1-infected protease inhibitor-experienced patientsQ43896562
Role of nicotianamine in the intracellular delivery of metals and plant reproductive developmentQ44463085
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Quercetin and Ascorbic Acid Suppress Fructose-Induced NLRP3 Inflammasome Activation by Blocking Intracellular Shuttling of TXNIP in Human Macrophage Cell LinesQ46399998
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Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease.Q53704198
Camostat Mesilate, Pancrelipase, and Rabeprazole Combination Therapy Improves Epigastric Pain in Early Chronic Pancreatitis and Functional Dyspepsia with Pancreatic Enzyme AbnormalitiesQ58616077
Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2Q58785257
Severe Acute Respiratory Syndrome Coronavirus Viroporin 3a Activates the NLRP3 InflammasomeQ61807081
Mechanism of Inhibition of Ebola Virus RNA-Dependent RNA Polymerase by RemdesivirQ64359892
Arbidol and Other Low-Molecular-Weight Drugs That Inhibit Lassa and Ebola VirusesQ64360387
Antiviral Efficacy of Flavonoids against Enterovirus 71 Infection in Vitro and in Newborn MiceQ66679210
Plasma Collection Using Nafamostat Mesilate and Dipyridamole as an AnticoagulantQ68467529
Pharmacological studies of FUT-175, nafamostat mesilate. V. Effects on the pancreatic enzymes and experimental acute pancreatitis in ratsQ68971878
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Effect of the synthetic protease inhibitor [N,N-dimethylcarbamoyl-methyl 4-(4-guanidinobenzoyloxy)-phenylacetate] methanesulfate on carcinogenesis by 3-methylcholanthrene in mouse skinQ70921966
Clinical experience with a protease inhibitor [N,N-dimethylcarbamoylmethyl 4-(4-guanidinobenzoyloxy)-phenylacetate] methanesulfate for prevention of recurrence of carcinoma of the mouth and in treatment of terminal carcinomaQ70953211
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Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitroQ84360011
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Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studiesQ86824600
The outbreak of COVID-19Q87226482
An updated estimation of the risk of transmission of the novel coronavirus (2019-nCov)Q87461382
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infectionQ87461568
Hydroxychloroquine and azithromycin as a treatment of COVID‐19: results of an open‐label non‐randomized clinical trialQ87908797
Structure, Function, and Antigenicity of the SARS-CoV-2 Spike GlycoproteinQ87973551
Genetic evolution analysis of 2019 novel coronavirus and coronavirus from other speciesQ88197712
Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitorsQ88219766
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease InhibitorQ88292103
A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19Q88370045
Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoVQ88486711
Repurposing of clinically approved drugs for treatment of coronavirus disease 2019 in a 2019-novel coronavirus (2019-nCoV) related coronavirus modelQ88486730
Flavonoids interfere with NLRP3 inflammasome activationQ89361879
Virological assessment of hospitalized patients with COVID-2019Q89379643
Learning from the Past: Possible Urgent Prevention and Treatment Options for Severe Acute Respiratory Infections Caused by 2019-nCoVQ89542749
P921main subjectCOVID-19Q84263196
SARS-CoV-2Q82069695
P304page(s)104859
P577publication date2020-04-29
2020-07-01
P1433published inPharmacological ResearchQ15724622
P1476titleCandidate drugs against SARS-CoV-2 and COVID-19
P478volume157

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