Current and Future Use of Chloroquine and Hydroxychloroquine in Infectious, Immune, Neoplastic, and Neurological Diseases: A Mini-Review.

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Current and Future Use of Chloroquine and Hydroxychloroquine in Infectious, Immune, Neoplastic, and Neurological Diseases: A Mini-Review. is …
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scholarly articleQ13442814

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P356DOI10.1007/S40261-018-0656-Y
P698PubMed publication ID29737455

P50authorDomenico PlantoneQ56944467
Tatiana KoudriavtsevaQ59661369
P2093author name stringTatiana Koudriavtseva
P2860cites workMicrobial translocation is a cause of systemic immune activation in chronic HIV infectionQ22251054
Drugs for discoid lupus erythematosusQ24240456
Chikungunya virus infectionQ24497757
Q feverQ24550722
Antimalarial Drug Resistance: Literature Review and Activities and Findings of the ICEMR NetworkQ26799713
Chloroquine and hydroxychloroquine for cancer therapyQ26827797
Cardiac toxicity secondary to long term treatment with chloroquineQ28360029
Chloroquine inhibits T cell proliferation by interfering with IL-2 production and responsivenessQ28367732
Chloroquine induces human mononuclear phagocytes to inhibit and kill Cryptococcus neoformans by a mechanism independent of iron deprivationQ28379104
Drug repurposing: a systematic approach to evaluate candidate oral neuroprotective interventions for secondary progressive multiple sclerosisQ28545984
Chikungunya virus: an update on the biology and pathogenesis of this emerging pathogenQ28599242
Baseline Prevalence of Birth Defects Associated with Congenital Zika Virus Infection — Massachusetts, North Carolina, and Atlanta, Georgia, 2013–2014Q28956693
Drug repositioning: identifying and developing new uses for existing drugsQ29614779
Assessing real-time Zika risk in the United StatesQ30145655
Drugs for discoid lupus erythematosus.Q30234556
Effect of chloroquine on reducing HIV-1 replication in vitro and the DC-SIGN mediated transfer of virus to CD4+ T-lymphocytes.Q30359528
The efficacy of hydroxychloroquine for obstetrical outcome in anti-phospholipid syndrome: Data from a European multicenter retrospective studyQ30885847
The anti-HIV-1 activity of chloroquineQ31884593
Factors associated with low bone mineral density in female patients with systemic lupus erythematosusQ31984501
Toll-like receptor ligands induce human T cell activation and death, a model for HIV pathogenesisQ33326642
Hydroxychloroquine in lupus pregnancyQ33373145
Is hydroxychloroquine effective in treating primary Sjogren's syndrome: a systematic review and meta-analysisQ33667694
Hydroxychloroquine protects the annexin A5 anticoagulant shield from disruption by antiphospholipid antibodies: evidence for a novel effect for an old antimalarial drugQ33747286
Effects of chloroquine on viral infections: an old drug against today's diseases?Q33973620
Antimalarial agents: closing the gate on Toll-like receptors?Q79158393
NeurosarcoidosisQ80184825
Ocular toxicity of hydroxychloroquineQ81141186
Porphyria cutanea tarda: treatment options revisitedQ84976648
The efficacy of hydroxychloroquine in altering pregnancy outcome in women with antiphospholipid antibodies. Evidence and clinical judgmentQ86328050
Whipple's diseaseQ88008833
Sjögren's syndromeQ88701707
New concepts in antimalarial use and mode of action in dermatologyQ34007922
Chloroquine and the fungal phagosomeQ34022942
Chloroquine-resistant malariaQ34087800
Clinical relapse in Whipple's disease despite maintenance therapyQ34098579
Hydroxychloroquine neuromyotoxicityQ34112561
Antimalarials.Q34129797
Retinal toxicity associated with hydroxychloroquine and chloroquine: risk factors, screening, and progression despite cessation of therapyQ34158360
Revised recommendations on screening for chloroquine and hydroxychloroquine retinopathyQ34162386
Chloroquine inhibits the intracellular multiplication of Legionella pneumophila by limiting the availability of iron. A potential new mechanism for the therapeutic effect of chloroquine against intracellular pathogensQ34226242
Global extent of chloroquine-resistant Plasmodium vivax: a systematic review and meta-analysisQ34259032
From methylene blue to chloroquine: a brief review of the development of an antimalarial therapyQ34260800
Antimalarials--the 'real' advance in lupusQ34297582
Chloroquine cardiomyopathy - a review of the literatureQ34342236
A favorable effect of hydroxychloroquine on glucose and lipid metabolism beyond its anti-inflammatory roleQ34389286
Chloroquine excretion following malaria prophylaxisQ34420993
Lysosomal sequestration of amine-containing drugs: analysis and therapeutic implicationsQ34583259
Efficacy and safety of hydroxychloroquine in the treatment of type 2 diabetes mellitus: a double blind, randomized comparison with pioglitazone.Q34660681
The history of lupus erythematosus. From Hippocrates to OslerQ34684696
Chronic ulcerative stomatitisQ34790917
Hydroxychloroquine-inhibited dengue virus is associated with host defense machineryQ35148912
Polymorphic light eruptionQ35200008
Bactericidal effect of doxycycline associated with lysosomotropic agents on Coxiella burnetii in P388D1 cellsQ35268754
Antiviral activity of chloroquine against dengue virus type 2 replication in Aotus monkeysQ35324935
Antimicrobial therapies for Q feverQ36169968
Hydroxychloroquine Blood Levels in Systemic Lupus Erythematosus: Clarifying Dosing Controversies and Improving AdherenceQ36240425
Decrease in macrophage antigen catabolism caused by ammonia and chloroquine is associated with inhibition of antigen presentation to T cellsQ36275163
Interventions for treating patients with chikungunya virus infection-related rheumatic and musculoskeletal disorders: A systematic reviewQ36400444
Cardiomyopathy related to antimalarial therapy with illustrative case reportQ36521126
Comparison of different antibiotic regimens for therapy of 32 cases of Q fever endocarditisQ36753137
Hydroxychloroquine directly reduces the binding of antiphospholipid antibody-beta2-glycoprotein I complexes to phospholipid bilayersQ36843689
Recycling of chloroquine and its hydroxyl analogue to face bacterial, fungal and viral infections in the 21st centuryQ36880738
Hydroxychloroquine use is associated with lower odds of persistently positive antiphospholipid antibodies and/or lupus anticoagulant in systemic lupus erythematosusQ37158591
Antiviral activity of chloroquine against human coronavirus OC43 infection in newborn miceQ37274730
The role of anti-malarials in rheumatoid arthritis--the American experience.Q41109179
Inhibition of HIV-1 replication by hydroxychloroquine: mechanism of action and comparison with zidovudineQ41152773
Inhibition of HIV-1 Tat-mediated transactivation by quinacrine and chloroquineQ41168935
Systemic lupus erythematosus; a report on twelve cases treated with quinacrine (atabrine) and chloroquine (aralen).Q41349197
Killing of Staphylococcus aureus in murine macrophages by chloroquine used alone and in combination with ciprofloxacin or azithromycinQ41476422
Targeting autophagy in cancerQ41912265
Chloroquine-induced cardiomyopathy-echocardiographic featuresQ41912397
Chloroquine neuromyotoxicity. Clinical and pathologic perspectiveQ41913997
Cytochrome P450 2C8 and CYP3A4/5 are involved in chloroquine metabolism in human liver microsomesQ41915280
Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine.Q41915692
Hydroxychloroquine reduces microglial activity and attenuates experimental autoimmune encephalomyelitis.Q41916874
Hydroxychloroquine concentration-response relationships in patients with rheumatoid arthritisQ41917273
Impact of hydroxychloroquine on preterm delivery and intrauterine growth restriction in pregnant women with systemic lupus erythematosus: a descriptive cohort studyQ41917416
Effect of hydroxychloroquine on progression of dementia in early Alzheimer's disease: an 18-month randomised, double-blind, placebo-controlled studyQ41919048
Hydroxychloroquine and pregnancy on lupus flares in Korean patients with systemic lupus erythematosus.Q41919912
The risk of toxic retinopathy in patients on long-term hydroxychloroquine therapyQ41920001
Dose refinements in long-term therapy of rheumatoid arthritis with antimalarialsQ41921005
Animal toxicity and pharmacokinetics of hydroxychloroquine sulfateQ41921033
Assessment of chloroquine as a modulator of immune activation to improve CD4 recovery in immune nonresponding HIV-infected patients receiving antiretroviral therapyQ41921243
Treatment of classic Whipple's disease: from in vitro results to clinical outcomeQ41924598
Treatment of Q fever endocarditis: comparison of 2 regimens containing doxycycline and ofloxacin or hydroxychloroquineQ41924708
Hypoglycemia induced by hydroxychloroquine in a type II diabetic treated for polyarthritis.Q41924789
Therapies for active rheumatoid arthritis after methotrexate failureQ41925478
Effectiveness of chloroquine and hydroxychloroquine in treating selected patients with sarcoidosis with neurological involvementQ41925667
Chloroquine modulates the fungal immune response in phagocytic cells from patients with chronic granulomatous diseaseQ41926522
Comparison of hydroxychloroquine with zidovudine in asymptomatic patients infected with human immunodeficiency virus type 1.Q41927429
Hydroxychloroquine reduces low-density lipoprotein cholesterol levels in systemic lupus erythematosus: a longitudinal evaluation of the lipid-lowering effect.Q41929433
Chloroquine and hydroxychloroquine equally affect tumor necrosis factor-alpha, interleukin 6, and interferon-gamma production by peripheral blood mononuclear cells.Q41929601
Efficacy of triple DMARD therapy in patients with RA with suboptimal response to methotrexateQ41931253
Hydroxychloroquine treatment of patients with human immunodeficiency virus type 1.Q41932765
Hydroxychloroquine drastically reduces immune activation in HIV-infected, antiretroviral therapy-treated immunologic nonrespondersQ41932770
Alterations in the internucleosomal DNA helical twist in chromatin of human erythroleukemia cells in vivo influences the chromatin higher‐order foldingQ41933313
Hypoglycemia induced by hydroxychloroquine in a patient treated for rheumatoid arthritisQ41934142
Hydroxychloroquine: a new therapeutic approach to the thrombotic manifestations of antiphospholipid syndromeQ41934841
On the inhibitory effect of chloroquine on blood platelet aggregationQ41935192
Use of antimalarials in dermatologyQ41935321
Induction of lysosomal dilatation, arrested autophagy, and cell death by chloroquine in cultured ARPE-19 cellsQ41935560
Hydroxychloroquine-induced myopathyQ41936886
Selective regulation of cytokine secretion by hydroxychloroquine: inhibition of interleukin 1 alpha (IL-1-alpha) and IL-6 in human monocytes and T cells.Q41937744
Effect of chloroquine on malignant lymphoreticular and pigmented cells in vitroQ41938039
Nuclear magnetic resonance studies of the interaction of chloroquine diphosphate with adenosine 5'-phosphate and other nucleotidesQ41939051
Comparative study of efficacy and safety of hydroxychloroquine and chloroquine in polymorphic light eruption: a randomized, double-blind, multicentric studyQ41941663
New clinical and ultrastructural findings in hydroxychloroquine-induced cardiomyopathy--a report of 2 casesQ41941843
Cholesterol-lowering effect of hydroxychloroquine in patients with rheumatic disease: reversal of deleterious effects of steroids on lipidsQ41943371
Hydroxychloroquine in decompensated, treatment-refractory noninsulin-dependent diabetes mellitus. A new job for an old drug?Q41943988
The in-vitro and ex-vivo effects of chloroquine sulphate on platelet function: implications for malaria prophylaxis in patients with impaired haemostasis.Q41944066
Chloroquine inhibits Paracoccidioides brasiliensis survival within human monocytes by limiting the availability of intracellular iron.Q41945512
Hydroxychloroquine-induced restrictive cardiomyopathyQ41945578
Effect of a malaria suppression program on the incidence of African Burkitt's lymphomaQ41945980
Chloroquine inhibits production of TNF-alpha, IL-1beta and IL-6 from lipopolysaccharide-stimulated human monocytes/macrophages by different modesQ41946037
Lupus erythematosus treated with a combination of quinacrine, hydroxychloroquine and chloroquineQ41946455
Hydroxychloroquine-induced cardiotoxicity in a 39-year-old woman with systemic lupus erythematosus and systolic dysfunctionQ41946807
Ocular effects and safety of antimalarial agentsQ41947045
Treatment of chronic lupus erythematosus with atabrine and chloroquineQ41947308
Chloroquine diphosphate in treatment of discoid lupus erythematosusQ41947617
Atabrine and chloroquine in the treatment of chronic discoid lupus erythematosus.Q41947620
Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS).Q42966712
CLIPPERS: Induction and maintenance of remission using hydroxychloroquineQ43112108
Serum immune activation markers are persistently increased in patients with HIV infection after 6 years of antiretroviral therapy despite suppression of viral replication and reconstitution of CD4+ T cellsQ43281341
Chloroquine inhibits tumor necrosis factor production by human macrophages in vitroQ44274859
Primary Sjogren's syndrome as a multi-organ disease: impact of the serological profile on the clinical presentation of the disease in a large cohort of Italian patients.Q44301752
Bone mineral density in postmenopausal Chinese patients with systemic lupus erythematosusQ45307599
Repurposing of the anti-malaria drug chloroquine for Zika Virus treatment and prophylaxisQ45324656
Hypoglycaemia induced by hydroxychloroquine in a non-diabetic patient treated for RA.Q46789109
Repurposing Drugs in Oncology (ReDO)-chloroquine and hydroxychloroquine as anti-cancer agents.Q47162451
Rational drug therapy recommendations for the treatment of patients with Sjögren's syndrome.Q52234497
The history of antimalarials.Q53622368
Whipple's DiseaseQ55933942
Drugs for discoid lupus erythematosusQ57692874
Mechanisms Involved in the Low‐Level Regeneration of CD4+Cells in HIV‐1–Infected Patients Receiving Highly Active Antiretroviral Therapy Who Have Prolonged Undetectable Plasma Viral LoadsQ61565774
Anti-annexin antibodies, cholesterol levels and disability in multiple sclerosisQ62580283
Possible efficacy of hydroxychloroquine on accelerated nodulosis during methotrexate therapy for rheumatoid arthritisQ70724673
Effect of low intraphagolysosomal pH on antimicrobial activity of antibiotics against ingested staphylococciQ71800112
Experimental results on chloroquine and AIDS-related opportunistic infectionsQ73594473
Effects of hydroxychloroquine on immune activation and disease progression among HIV-infected patients not receiving antiretroviral therapy: a randomized controlled trialQ37289596
Clinical efficacy and side effects of antimalarials in systemic lupus erythematosus: a systematic reviewQ37356697
Ocular safety of hydroxychloroquine.Q37519428
Thrombosis in systemic lupus erythematosus: risk and protectionQ37642828
Accelerated atherosclerosis in SLE: mechanisms and prevention approachesQ37658524
Chloroquine use improves dengue-related symptomsQ37674854
Use of hydroxychloroquine to prevent thrombosis in systemic lupus erythematosus and in antiphospholipid antibody-positive patientsQ37803363
Hydroxychloroquine: from malaria to autoimmunityQ37827403
Maintenance of CD4+ T-cell memory and HIV persistence: keeping memory, keeping HIV.Q37829627
Disparity between visual fields and optical coherence tomography in hydroxychloroquine retinopathyQ38179651
Hydroxychloroquine: a multifaceted treatment in lupusQ38214068
Tropheryma whipplei and Whipple's diseaseQ38216060
Hydroxychloroquine preferentially induces apoptosis of CD45RO+ effector T cells by inhibiting autophagy: a possible mechanism for therapeutic modulation of T cellsQ38282082
Hydroxychloroquine-induced cardiomyopathy: case report, pathophysiology, diagnosis, and treatment.Q38283188
Hydroxychloroquine as an anti-thrombotic in antiphospholipid syndromeQ38297919
Chloroquine analogues in drug discovery: new directions of uses, mechanisms of actions and toxic manifestations from malaria to multifarious diseasesQ38360827
Antibiotic treatment and relapse in Whipple's disease. Long-term follow-up of 88 patientsQ38394341
Recent advances in the study of Q fever epidemiology, diagnosis and managementQ38445496
Chloroquine and beyond: exploring anti-rheumatic drugs to reduce immune hyperactivation in HIV/AIDS.Q38530430
Therapy and pharmacological properties of hydroxychloroquine and chloroquine in treatment of systemic lupus erythematosus, rheumatoid arthritis and related diseasesQ38561490
Involvement of inflammation in Alzheimer's disease pathogenesis and therapeutic potential of anti-inflammatory agents.Q38569669
The use of quinacrine (Atabrine) in rheumatic diseases: a reexaminationQ38637388
Complications of antimalarial therapyQ38668320
Time to use a dose of Chloroquine as an adjuvant to anti-cancer chemotherapiesQ38674653
Research progress of hydroxychloroquine and autophagy inhibitors on cancer.Q39021076
Hydroxychloroquine in systemic lupus erythematosus (SLE).Q39031764
Chloroquine engages the immune system to eradicate irradiated breast tumors in miceQ39076936
Targeting endosomal acidification by chloroquine analogs as a promising strategy for the treatment of emerging viral diseasesQ39360987
Antitumor and antimetastatic activities of chloroquine diphosphate in a murine model of breast cancerQ39649021
Chloroquine stimulates nitric oxide synthesis in murine, porcine, and human endothelial cellsQ39807701
Chloroquine inhibits colon cancer cell growth in vitro and tumor growth in vivo via induction of apoptosisQ39887289
Cell growth inhibition, G2/M cell cycle arrest, and apoptosis induced by chloroquine in human breast cancer cell line Bcap-37.Q39904465
Efficacy of combination DMARD therapy vs. hydroxychloroquine monotherapy in chronic persistent chikungunya arthritis: a 24-week randomized controlled open label studyQ40086492
Coxiella burnetii infection of aortic aneurysms or vascular grafts: report of 30 new cases and evaluation of outcomeQ40444558
The impact of hydroxychloroquine treatment on pregnancy outcome in women with antiphospholipid antibodies.Q40474976
Fungistatic effect of hydroxychloroquine, lessons from a caseQ40515410
Pregnancy outcome of 126 anti-SSA/Ro-positive patients during the past 24 years--a retrospective cohort studyQ40524514
Anti-HIV effects of chloroquine: inhibition of viral particle glycosylation and synergism with protease inhibitors.Q40568140
Antimalarial quinolines and artemisinin inhibit endocytosis in Plasmodium falciparumQ40968248
P433issue8
P921main subjecthydroxychloroquineQ421094
chloroquineQ422438
P304page(s)653-671
P577publication date2018-08-01
P1433published inClinical Drug InvestigationQ15753215
P1476titleCurrent and Future Use of Chloroquine and Hydroxychloroquine in Infectious, Immune, Neoplastic, and Neurological Diseases: A Mini-Review
P478volume38