| scholarly article | Q13442814 |
| P50 | author | Heinrich C. Hoppe | Q41811744 |
| P2093 | author name string | Donelly A van Schalkwyk | |
| Brandon W Weber | |||
| Joanne Egan | |||
| Sandra A Meredith | |||
| Ursula I M Wiehart | |||
| P2860 | cites work | Artemisinin, an Endoperoxide Antimalarial, Disrupts the Hemoglobin Catabolism and Heme Detoxification Systems in Malarial Parasite | Q22061847 |
| Artemisinins target the SERCA of Plasmodium falciparum | Q22061877 | ||
| On the molecular mechanism of chloroquine's antimalarial action | Q24603529 | ||
| The effect of artesunate combined with standard antimalarials against chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum in vitro | Q28370483 | ||
| Synchronization of Plasmodium falciparum Erythrocytic Stages in Culture | Q29547549 | ||
| SERCA pump level is a critical determinant of Ca(2+)homeostasis and cardiac contractility | Q34083460 | ||
| Synaptic vesicle endocytosis: calcium works overtime in the nerve terminal | Q34286893 | ||
| Aspartic proteases of Plasmodium falciparum and other parasitic protozoa as drug targets. | Q34548661 | ||
| The pH of the Plasmodium falciparum digestive vacuole: holy grail or dead-end trail? | Q34960497 | ||
| Effects of amodiaquine, chloroquine, and mefloquine on human polymorphonuclear neutrophil function in vitro | Q35316198 | ||
| Recycling of the asialoglycoprotein receptor and the effect of lysosomotropic amines in hepatoma cells | Q36209945 | ||
| Antimalarials increase vesicle pH in Plasmodium falciparum | Q36213878 | ||
| Ultrastructural basis for chloroquine-induced increase in intracellular insulin in adipocytes: alteration of lysosomal function | Q36323386 | ||
| Artemisinin and the antimalarial endoperoxides: from herbal remedy to targeted chemotherapy. | Q36671618 | ||
| An iron-carboxylate bond links the heme units of malaria pigment | Q37366154 | ||
| Distribution of acridine orange fluorescence in Plasmodium falciparum-infected erythrocytes and its implications for the evaluation of digestive vacuole pH. | Q38920321 | ||
| Central role of hemoglobin degradation in mechanisms of action of 4-aminoquinolines, quinoline methanols, and phenanthrene methanols | Q39559476 | ||
| Hemoglobin degradation in Plasmodium-infected red blood cells | Q40788938 | ||
| Primaquine interferes with membrane recycling from endosomes to the plasma membrane through a direct interaction with endosomes which does not involve neutralisation of endosomal pH nor osmotic swelling of endosomes | Q40864032 | ||
| The mode of action of the antimalarial artemisinin and its derivatives | Q41148700 | ||
| Identification of the acidic compartment of Plasmodium falciparum-infected human erythrocytes as the target of the antimalarial drug chloroquine | Q41584415 | ||
| Cellular uptake of chloroquine is dependent on binding to ferriprotoporphyrin IX and is independent of NHE activity in Plasmodium falciparum | Q41819350 | ||
| Ultrastructural study of the effects of chloroquine and verapamil on Plasmodium falciparum | Q41911834 | ||
| Inhibition of hemoglobin degradation in Plasmodium falciparum by chloroquine and ammonium chloride | Q41913007 | ||
| An ultrastructural study of the effects of mefloquine on malaria parasites | Q41914360 | ||
| Stage-dependent inhibition of chloroquine on Plasmodium falciparum in vitro. | Q41914764 | ||
| Uptake of [3H]chloroquine by drug-sensitive and -resistant strains of the human malaria parasite Plasmodium falciparum | Q41914857 | ||
| Characterization of a hemoglobin-degrading, low molecular weight protease from Plasmodium falciparum | Q41915792 | ||
| A perspective on antimalarial action: effects of weak bases on Plasmodium falciparum | Q41915834 | ||
| Relationship of chloroquine-induced redistribution of a neutral aminopeptidase to hemoglobin accumulation in malaria parasites | Q41916355 | ||
| Mechanism of cationic amphiphilic drug inhibition of purified lysosomal phospholipase A1. | Q41916467 | ||
| Qinghaosu-induced changes in the morphology of Plasmodium inui. | Q41917102 | ||
| Structure-activity relationships in 4-aminoquinoline antiplasmodials. The role of the group at the 7-position | Q41917156 | ||
| Differential effects of 4-aminoquinoline-containing antimalarial drugs on hemoglobin digestion in Plasmodium falciparum-infected erythrocytes | Q41917894 | ||
| Interactions of hemin, antimalarial drugs and hemin-antimalarial complexes with phospholipid monolayers | Q41918525 | ||
| Effects of chloroquine on the feeding mechanism of the intraerythrocytic human malarial parasite Plasmodium falciparum | Q41918836 | ||
| The effects of chloroquine and verapamil on digestive vacuolar pH of P. falciparum either sensitive or resistant to chloroquine | Q41921086 | ||
| Chloroquine diverts ACTH from a regulated to a constitutive secretory pathway in AtT-20 cells | Q41921642 | ||
| Inhibition of Semliki forest virus penetration by lysosomotropic weak bases | Q41923695 | ||
| A common mechanism for blockade of heme polymerization by antimalarial quinolines | Q41925197 | ||
| Quinoline antimalarials: mechanisms of action and resistance and prospects for new agents | Q41925737 | ||
| An assessment of drug-haematin binding as a mechanism for inhibition of haematin polymerisation by quinoline antimalarials | Q41926615 | ||
| Chloroquine and ammonium ion inhibit receptor-mediated endocytosis of mannose-glycoconjugates by macrophages: apparent inhibition of receptor recycling | Q41927015 | ||
| Quinoline anti-malarial drugs inhibit spontaneous formation of beta-haematin (malaria pigment). | Q41934645 | ||
| Inhibition by chloroquine of a novel haem polymerase enzyme activity in malaria trophozoites | Q41940707 | ||
| Three-dimensional reconstruction of the feeding process of the malaria parasite | Q41944860 | ||
| Alkalinization of the food vacuole of malaria parasites by quinoline drugs and alkylamines is not correlated with their antimalarial activity | Q41945440 | ||
| Intraerythrocytic Plasmodium falciparum utilizes only a fraction of the amino acids derived from the digestion of host cell cytosol for the biosynthesis of its proteins | Q43868723 | ||
| Acidic calcium pools in intraerythrocytic malaria parasites. | Q47718912 | ||
| Excess hemoglobin digestion and the osmotic stability of Plasmodium falciparum-infected red blood cells. | Q52024420 | ||
| Heme transfer between phospholipid membranes and uptake by apohemoglobin. | Q52667798 | ||
| The effect of artemisinin on granulocyte function assessed by flow cytometry. | Q54574185 | ||
| Plasmodium falciparum: sacrificing membrane to grow crystals? | Q63386634 | ||
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Plasmodium falciparum | Q311383 |
| artemisinin | Q426921 | ||
| antimalarial | Q521616 | ||
| P304 | page(s) | 2370-2378 | |
| P577 | publication date | 2004-07-01 | |
| P1433 | published in | Antimicrobial Agents and Chemotherapy | Q578004 |
| P1476 | title | Antimalarial quinolines and artemisinin inhibit endocytosis in Plasmodium falciparum | |
| P478 | volume | 48 |
| Q37409282 | A new model for hemoglobin ingestion and transport by the human malaria parasite Plasmodium falciparum |
| Q28482292 | Activity of clinically relevant antimalarial drugs on Plasmodium falciparum mature gametocytes in an ATP bioluminescence "transmission blocking" assay |
| Q36055139 | Amino acid efflux by asexual blood-stage Plasmodium falciparum and its utility in interrogating the kinetics of hemoglobin endocytosis and catabolism in vivo |
| Q36652599 | Antimalarial drug therapy: the role of parasite biology and drug resistance |
| Q28276294 | Artemisinin Action and Resistance in Plasmodium falciparum |
| Q35105092 | Artemisinin activity against Plasmodium falciparum requires hemoglobin uptake and digestion |
| Q22061805 | Artemisinin and a Series of Novel Endoperoxide Antimalarials Exert Early Effects on Digestive Vacuole Morphology |
| Q36849304 | Artemisinin resistance in rodent malaria--mutation in the AP2 adaptor μ-chain suggests involvement of endocytosis and membrane protein trafficking |
| Q34084173 | Artemisone effective against murine cerebral malaria |
| Q96231357 | Artesunate: could be an alternative drug to chloroquine in COVID-19 treatment? |
| Q38201049 | Autophagy in Plasmodium, a multifunctional pathway? |
| Q54218397 | Current and Future Use of Chloroquine and Hydroxychloroquine in Infectious, Immune, Neoplastic, and Neurological Diseases: A Mini-Review. |
| Q36469382 | Current opinion on an emergence of drug resistant strains of Plasmodium falciparum through genetic alterations |
| Q22061943 | Current perspectives on the mechanism of action of artemisinins |
| Q36951722 | Current therapies and future possibilities for drug development against liver-stage malaria |
| Q36788489 | Cysteamine, the natural metabolite of pantetheinase, shows specific activity against Plasmodium |
| Q41910682 | Differential effects of quinoline antimalarials on endocytosis in Plasmodium falciparum |
| Q38093645 | Dual-functioning antimalarials that inhibit the chloroquine-resistance transporter |
| Q35573542 | Global gene expression profiling of Plasmodium falciparum in response to the anti-malarial drug pyronaridine |
| Q28828253 | Hemozoin and antimalarial drug discovery |
| Q41827568 | Investigations into the role of the Plasmodium falciparum SERCA (PfATP6) L263E mutation in artemisinin action and resistance |
| Q46160167 | Kinetics of beta-haematin formation from suspensions of haematin in aqueous benzoic acid |
| Q36832446 | Malaria chemotherapeutics part I: History of antimalarial drug development, currently used therapeutics, and drugs in clinical development |
| Q46525450 | Mefloquine induces ROS mediated programmed cell death in malaria parasite: Plasmodium |
| Q57013585 | Other 4-Methanolquinolines, Amyl Alcohols and Phentathrenes: Mefloquine, Lumefantrine and Halofantrine |
| Q35149404 | PfMDR2 and PfMDR5 are dispensable for Plasmodium falciparum asexual parasite multiplication but change in vitro susceptibility to anti-malarial drugs |
| Q30043721 | PfPI3K, a phosphatidylinositol-3 kinase from Plasmodium falciparum, is exported to the host erythrocyte and is involved in hemoglobin trafficking |
| Q37041253 | Psychological stress exacerbates primary vaginal herpes simplex virus type 1 (HSV-1) infection by impairing both innate and adaptive immune responses |
| Q37041318 | Psychological stress impairs the local CD8+ T cell response to mucosal HSV-1 infection and allows for increased pathogenicity via a glucocorticoid receptor-mediated mechanism |
| Q22061846 | Purified E255L Mutant SERCA1a and Purified PfATP6 Are Sensitive to SERCA-type Inhibitors but Insensitive to Artemisinins |
| Q39947285 | Role of Plasmodium falciparum digestive vacuole plasmepsins in the specificity and antimalarial mode of action of cysteine and aspartic protease inhibitors |
| Q100761990 | Spirofused tetrahydroisoquinoline-oxindole hybrids as a novel class of fast acting antimalarial agents with multiple modes of action |
| Q33697242 | The Plasmodium protein network diverges from those of other eukaryotes |
| Q34721762 | The antimalarial artemisinin synergizes with antibiotics to protect against lethal live Escherichia coli challenge by decreasing proinflammatory cytokine release |
| Q30489505 | The malarial parasite Plasmodium falciparum imports the human protein peroxiredoxin 2 for peroxide detoxification |
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