Chloroquine inhibits Paracoccidioides brasiliensis survival within human monocytes by limiting the availability of intracellular iron.

scientific article published on January 2006

Chloroquine inhibits Paracoccidioides brasiliensis survival within human monocytes by limiting the availability of intracellular iron. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1348-0421.2006.TB03798.X
P698PubMed publication ID16625052
P5875ResearchGate publication ID7155536

P50authorLuciane Alarcão Dias-MelicioQ44774730
Sueli Aparecida CalviQ117278899
Angela Maria Victoriano de Campos SoaresQ117278901
P2093author name stringAna Paula Moreira
P2860cites workChanges in function of iron-loaded alveolar macrophages after in vivo administration of desferrioxamine and/or chloroquineQ41916270
Lysosomal origin of the ferric iron required for cell killing by hydrogen peroxideQ41916319
Effect of chronic chloroquine administration on iron loading in the liver and reticuloendothelial system and on oxidative responses by the alveolar macrophages.Q41924459
Uptake of ferritin and iron bound to ferritin by rat hepatocytes: modulation by apotransferrin, iron chelators and chloroquineQ41946261
Chelation of transferrin iron by desferrioxamine in K562 cells. The partition of iron between ferrioxamine and ferritinQ42817835
Inhibitory effect of deferoxamine on Paracoccidioides brasiliensis survival in human monocytes: reversal by holotransferrin not by apotransferrinQ46815420
Statistics in practice. Comparing the means of several groups.Q52656150
Role of iron in experimental Mycobacterium avium infectionQ57617789
Chloroquine induces human mononuclear phagocytes to inhibit and kill Cryptococcus neoformans by a mechanism independent of iron deprivationQ28379104
Iron absorption and transportQ33752139
Regulation of transferrin receptor expression and ferritin content in human mononuclear phagocytes. Coordinate upregulation by iron transferrin and downregulation by interferon gammaQ33893144
Iron and Mycobacterium tuberculosis infectionQ34134803
Chloroquine induces human macrophage killing of Histoplasma capsulatum by limiting the availability of intracellular iron and is therapeutic in a murine model of histoplasmosisQ34137889
Chloroquine inhibits the intracellular multiplication of Legionella pneumophila by limiting the availability of iron. A potential new mechanism for the therapeutic effect of chloroquine against intracellular pathogensQ34226242
Interferon gamma-activated human monocytes downregulate transferrin receptors and inhibit the intracellular multiplication of Legionella pneumophila by limiting the availability of ironQ34571751
Role of iron in Trypanosoma cruzi infection of miceQ34603205
Nitric oxide-mediated modulation of iron regulatory proteins: implication for cellular iron homeostasisQ35053282
Inhibition of growth of Histoplasma capsulatum yeast cells in human macrophages by the iron chelator VUF 8514 and comparison of VUF 8514 with deferoxamineQ35117471
Role of transferrin, transferrin receptors, and iron in macrophage listericidal activityQ36230297
pH and the recycling of transferrin during receptor-mediated endocytosisQ37609089
Effect of cytokines on the in vitro fungicidal activity of monocytes from paracoccidioidomycosis patientsQ38929645
The Effect of pH upon Human Transferrin: Selective Labelling of the Two Iron-binding SitesQ39080353
Modulatory effect of prostaglandins on human monocyte activation for killing of high- and low-virulence strains of Paracoccidioides brasiliensisQ39474809
Acid-vesicle function, intracellular pathogens, and the action of chloroquine against Plasmodium falciparumQ39663518
Difference between the two iron-binding sites of transferrinQ40318488
Effects of interferon-gamma and lipopolysaccharide on macrophage iron metabolism are mediated by nitric oxide-induced degradation of iron regulatory protein 2.Q40897847
Control of transferrin receptor expression via nitric oxide-mediated modulation of iron-regulatory protein 2.Q40919235
Iron metabolism of established human hematopoietic cell lines in vitroQ41583784
Chloroquine reduces neuronal and glial iron uptakeQ41915862
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectParacoccidioides brasiliensisQ310186
chloroquineQ422438
P304page(s)307-314
P577publication date2006-01-01
P1433published inMicrobiology and ImmunologyQ15767399
P1476titleChloroquine inhibits Paracoccidioides brasiliensis survival within human monocytes by limiting the availability of intracellular iron
P478volume50

Reverse relations

cites work (P2860)
Q37161425An encapsulation of iron homeostasis and virulence in Cryptococcus neoformans.
Q38773638Chloroquine inhibits Rhodococcus equi replication in murine and foal alveolar macrophages by iron-starvation
Q54218397Current and Future Use of Chloroquine and Hydroxychloroquine in Infectious, Immune, Neoplastic, and Neurological Diseases: A Mini-Review.
Q37097977Fungal adaptation to the mammalian host: it is a new world, after all.
Q33618005Hemoglobin uptake by Paracoccidioides spp. is receptor-mediated
Q36880738Recycling of chloroquine and its hydroxyl analogue to face bacterial, fungal and viral infections in the 21st century
Q35384216Regulatory T-cell Trafficking: From Thymic Development to Tumor-Induced Immune Suppression
Q58696251Serological proteomic biomarkers to identify Paracoccidioides species and risk of relapse
Q38889897The role of leukotriene B4 in early stages of experimental paracoccidioidomycosis induced in phenotypically selected mouse strains

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