Serious Non-AIDS Events: Therapeutic Targets of Immune Activation and Chronic Inflammation in HIV Infection

scientific article published on 25 February 2016

Serious Non-AIDS Events: Therapeutic Targets of Immune Activation and Chronic Inflammation in HIV Infection is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1038655800
P356DOI10.1007/S40265-016-0546-7
P8608Fatcat IDrelease_xxgb3dklgzecxj63hecfpppt2a
P932PMC publication ID5578711
P698PubMed publication ID26915027
P5875ResearchGate publication ID295868156

P50authorIrini SeretiQ37383379
P2093author name stringDenise C Hsu
P2860cites workCD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tractQ22242965
Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infectionQ22251080
Apoptosis, pyroptosis, and necrosis: mechanistic description of dead and dying eukaryotic cellsQ24523640
Life expectancy of individuals on combination antiretroviral therapy in high-income countries: a collaborative analysis of 14 cohort studiesQ24597052
Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trialsQ24645391
Innate immune recognition of HIV-1Q27025598
Maintenance of intestinal Th17 cells and reduced microbial translocation in SIV-infected rhesus macaques treated with interleukin (IL)-21Q27334401
CD8(+) T cell activation in women coinfected with human immunodeficiency virus type 1 and hepatitis C virusQ27486398
The impact of hepatitis C virus coinfection on HIV-related kidney disease: a systematic review and meta-analysisQ27489415
High levels of chronic immune activation in the T-cell compartments of patients coinfected with hepatitis C virus and human immunodeficiency virus type 1 and on highly active antiretroviral therapy are reverted by alpha interferon and ribavirin treaQ27490328
IL-17 and Th17 CellsQ27860566
Immunity, Inflammation, and CancerQ27861048
General issues on microbial translocation in HIV-infected patientsQ28081220
Cholesterol, inflammation and innate immunityQ28086912
Increased production of IL-7 accompanies HIV-1-mediated T-cell depletion: implications for T-cell homeostasisQ28141430
Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cellsQ28215003
Type I interferons in infectious diseaseQ28255842
Rifaximin treatment in hepatic encephalopathyQ28277660
Inflammatory and coagulation biomarkers and mortality in patients with HIV infectionQ28473903
The effect of raltegravir intensification on low-level residual viremia in HIV-infected patients on antiretroviral therapy: a randomized controlled trialQ28475076
Inflammation, coagulation and cardiovascular disease in HIV-infected individualsQ28483645
Angiotensin converting enzyme inhibitor and HMG-CoA reductase inhibitor as adjunct treatment for persons with HIV infection: a feasibility randomized trialQ28484460
Systematic review of antiretroviral-associated lipodystrophy: lipoatrophy, but not central fat gain, is an antiretroviral adverse drug reactionQ28533379
Intensification of antiretroviral therapy with a CCR5 antagonist in patients with chronic HIV-1 infection: effect on T cells latently infectedQ28741704
Long-term interleukin-6 levels and subsequent risk of coronary heart disease: two new prospective studies and a systematic reviewQ28755180
Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statinsQ29547856
The growing burden of tuberculosis: global trends and interactions with the HIV epidemicQ29616520
CD4+ count-guided interruption of antiretroviral treatmentQ29619489
2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice GuidelinesQ29620108
HIV and Tuberculosis: a Deadly Human SyndemicQ30052157
Efficacy and safety of LDL-lowering therapy among men and women: meta-analysis of individual data from 174,000 participants in 27 randomised trialsQ30884055
Safety of low dose glucocorticoid treatment in rheumatoid arthritis: published evidence and prospective trial data.Q31000488
Incidence and risk factors for new-onset diabetes in HIV-infected patients: the Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) studyQ31146395
The anti-HIV-1 activity of chloroquineQ31884593
HIV induces TRAIL sensitivity in hepatocytesQ33413051
HIV-1 residual viremia correlates with persistent T-cell activation in poor immunological responders to combination antiretroviral therapy.Q33513977
Exposure to HIV-1 directly impairs mucosal epithelial barrier integrity allowing microbial translocationQ33553358
Meta-analysis: increased mortality associated with hepatitis C in HIV-infected persons is unrelated to HIV disease progressionQ33585762
Increased tissue factor expression on circulating monocytes in chronic HIV infection: relationship to in vivo coagulation and immune activationQ33597485
Predicting risk of cancer during HIV infection: the role of inflammatory and coagulation biomarkersQ33713347
Mitochondrial toxicity induced by nucleoside-analogue reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophyQ33745859
Interleukin-2 therapy in patients with HIV infectionQ33847543
Molecular and cellular mechanisms of angiotensin II-mediated cardiovascular and renal diseasesQ33852885
Markers of inflammation, coagulation, and renal function are elevated in adults with HIV infectionQ33857515
Early microbial translocation blockade reduces SIV-mediated inflammation and viral replicationQ33872468
Dysbiosis of the gut microbiota is associated with HIV disease progression and tryptophan catabolismQ33889154
Traditional risk factors and D-dimer predict incident cardiovascular disease events in chronic HIV infectionQ33907642
Metabolic syndrome, C-reactive protein, and mortality in U.S. Blacks and Whites: the Reasons for Geographic and Racial Differences in Stroke (REGARDS) studyQ33960247
Association between use of HMG CoA reductase inhibitors and mortality in HIV-infected patientsQ33963850
IL-2-induced CD4+ T-cell expansion in HIV-infected patients is associated with long-term decreases in T-cell proliferationQ33977594
A randomized open-label study of 3- versus 5-drug combination antiretroviral therapy in newly HIV-1-infected individualsQ34009093
Lymphoid tissue damage in HIV-1 infection depletes naïve T cells and limits T cell reconstitution after antiretroviral therapy.Q34126302
Mucosal immunity in human and simian immunodeficiency lentivirus infectionsQ34131265
T Cell Activation Is Associated with Lower CD4+T Cell Gains in Human Immunodeficiency Virus–Infected Patients with Sustained Viral Suppression during Antiretroviral TherapyQ34193786
Inflammation and mortality in HIV-infected adults: analysis of the FRAM study cohortQ34204026
Factors associated with CD8+ T-cell activation in HIV-1-infected patients on long-term antiretroviral therapyQ34206123
X4 Human immunodeficiency virus type 1 gp120 promotes human hepatic stellate cell activation and collagen I expression through interactions with CXCR4Q34221539
Physiology. COX-2 inhibitors and cardiovascular riskQ34281737
Gut epithelial barrier dysfunction and innate immune activation predict mortality in treated HIV infectionQ34315572
Randomized pilot trial of a synbiotic dietary supplement in chronic HIV-1 infectionQ34322219
Effect of raltegravir-containing intensification on HIV burden and T-cell activation in multiple gut sites of HIV-positive adults on suppressive antiretroviral therapyQ34384143
Sevelamer does not decrease lipopolysaccharide or soluble CD14 levels but decreases soluble tissue factor, low-density lipoprotein (LDL) cholesterol, and oxidized LDL cholesterol levels in individuals with untreated HIV infectionQ34430215
Effect of probiotics (Saccharomyces boulardii) on microbial translocation and inflammation in HIV-treated patients: a double-blind, randomized, placebo-controlled trialQ34451794
Increased platelet and microparticle activation in HIV infection: upregulation of P-selectin and tissue factor expressionQ35823171
A systematic review of sevelamer in ESRD and an analysis of its potential economic impact in Canada and the United StatesQ35870443
Meta-analysis: glycosylated hemoglobin and cardiovascular disease in diabetes mellitusQ35894298
The Interplay Between Host Genetic Variation, Viral Replication, and Microbial Translocation in Untreated HIV-Infected IndividualsQ35965167
Effect of phosphate binders on serum inflammatory profile, soluble CD14, and endotoxin levels in hemodialysis patientsQ35983529
Effects of recombinant human interleukin 7 on T-cell recovery and thymic output in HIV-infected patients receiving antiretroviral therapy: results of a phase I/IIa randomized, placebo-controlled, multicenter studyQ36053935
Rifaximin: in vitro and in vivo antibacterial activity--a reviewQ36108484
Current perspectives on HIV-associated lipodystrophy syndromeQ36132967
Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individualsQ36230977
Anti-inflammatory effects of statins: clinical evidence and basic mechanismsQ36337932
Epidemiology of viral hepatitis and HIV co-infectionQ36341016
A pilot trial of adding maraviroc to suppressive antiretroviral therapy for suboptimal CD4⁺ T-cell recovery despite sustained virologic suppression: ACTG A5256.Q36379230
HIV status, burden of comorbid disease, and biomarkers of inflammation, altered coagulation, and monocyte activationQ36383621
Early impairment of gut function and gut flora supporting a role for alteration of gastrointestinal mucosa in human immunodeficiency virus pathogenesisQ36452414
Microbial translocation in the pathogenesis of HIV infection and AIDS.Q36558287
Reduced inflammation and lymphoid tissue immunopathology in rhesus macaques receiving anti-tumor necrosis factor treatment during primary simian immunodeficiency virus infectionQ36607248
Accelerated immune senescence and HIV-1 infectionQ36738887
Prebiotics: the concept revisitedQ36740886
CD4+ count and risk of non-AIDS diseases following initial treatment for HIV infectionQ36745251
Effects of statin therapy on coronary artery plaque volume and high-risk plaque morphology in HIV-infected patients with subclinical atherosclerosis: a randomised, double-blind, placebo-controlled trialQ36765204
Lubiprostone: a chloride channel activator for treatment of chronic constipationQ36829143
Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infectionsQ36915902
The immunologic effects of maraviroc intensification in treated HIV-infected individuals with incomplete CD4+ T-cell recovery: a randomized trialQ36938539
Ledipasvir and Sofosbuvir for HCV in Patients Coinfected with HIV-1.Q36967076
HIV infection-associated immune activation occurs by two distinct pathways that differentially affect CD4 and CD8 T cellsQ37000907
A meta-analysis of six placebo-controlled trials of thiazolidinedione therapy for HIV lipoatrophyQ37070314
Aspirin attenuates platelet activation and immune activation in HIV-1-infected subjects on antiretroviral therapy: a pilot studyQ37130166
Immune effector mechanisms implicated in atherosclerosis: from mice to humansQ37150605
The effects of recombinant human leptin on visceral fat, dyslipidemia, and insulin resistance in patients with human immunodeficiency virus-associated lipoatrophy and hypoleptinemiaQ37193194
Sofosbuvir and ribavirin for hepatitis C in patients with HIV coinfectionQ37202576
Increase in 2-long terminal repeat circles and decrease in D-dimer after raltegravir intensification in patients with treated HIV infection: a randomized, placebo-controlled trialQ37213057
IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infectionQ37262403
Serum oxidized low-density lipoprotein decreases in response to statin therapy and relates independently to reductions in coronary plaque in patients with HIV.Q37294964
Initiation of Antiretroviral Therapy in Early Asymptomatic HIV InfectionQ34485916
Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysisQ34507164
Prostaglandins as modulators of immunityQ34543566
Lymphatic tissue fibrosis is associated with reduced numbers of naive CD4+ T cells in human immunodeficiency virus type 1 infection.Q34601557
The multifaceted role of pirfenidone and its novel targets.Q34623073
Cumulative mechanisms of lymphoid tissue fibrosis and T cell depletion in HIV-1 and SIV infectionsQ34627187
The risk of tuberculosis related to tumour necrosis factor antagonist therapies: a TBNET consensus statementQ34660076
Leptin replacement improves postprandial glycemia and insulin sensitivity in human immunodeficiency virus–infected lipoatrophic men treated with pioglitazone: a pilot studyQ34672147
Immune biomarker differences and changes comparing HCV mono-infected, HIV/HCV co-infected, and HCV spontaneously cleared patientsQ34673075
A randomized, controlled trial of raltegravir intensification in antiretroviral-treated, HIV-infected patients with a suboptimal CD4+ T cell responseQ34743336
Plasma levels of soluble CD14 independently predict mortality in HIV infectionQ34764002
T cell activation and senescence predict subclinical carotid artery disease in HIV-infected womenQ34764361
The immunologic effects of mesalamine in treated HIV-infected individuals with incomplete CD4+ T cell recovery: a randomized crossover trialQ34818798
Severity of cardiovascular disease outcomes among patients with HIV is related to markers of inflammation and coagulationQ35021902
Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganismsQ35024882
The effect of HAART-induced HIV suppression on circulating markers of inflammation and immune activationQ35030011
Comparison of risk and age at diagnosis of myocardial infarction, end-stage renal disease, and non-AIDS-defining cancer in HIV-infected versus uninfected adults.Q35055172
The effect of hepatitis C virologic clearance on cardiovascular disease biomarkers in human immunodeficiency virus/hepatitis C virus coinfectionQ35072020
An exploratory trial of cyclooxygenase type 2 inhibitor in HIV-1 infection: downregulated immune activation and improved T cell-dependent vaccine responsesQ35077490
Rosuvastatin reduces vascular inflammation and T-cell and monocyte activation in HIV-infected subjects on antiretroviral therapyQ35102167
Rifaximin has a marginal impact on microbial translocation, T-cell activation and inflammation in HIV-positive immune non-responders to antiretroviral therapy - ACTG A5286.Q35102590
Antifibrotic therapy in simian immunodeficiency virus infection preserves CD4+ T-cell populations and improves immune reconstitution with antiretroviral therapyQ35102598
The associations of regional adipose tissue with lipid and lipoprotein levels in HIV-infected men.Q35166131
Causes of death in HIV-1-infected patients treated with antiretroviral therapy, 1996-2006: collaborative analysis of 13 HIV cohort studiesQ35169664
Specific prebiotics modulate gut microbiota and immune activation in HAART-naive HIV-infected adults: results of the "COPA" pilot randomized trialQ35171253
The risk of incident coronary heart disease among veterans with and without HIV and hepatitis CQ35174850
C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysisQ35182277
Trends in CD4 count at presentation to care and treatment initiation in sub-Saharan Africa, 2002-2013: a meta-analysisQ35197266
Raltegravir treatment intensification does not alter cerebrospinal fluid HIV-1 infection or immunoactivation in subjects on suppressive therapyQ35532868
Oxidized LDL Levels Are Increased in HIV Infection and May Drive Monocyte Activation.Q35655728
Soluble CD14 is a nonspecific marker of monocyte activationQ35676127
Is Impact of Statin Therapy on All-Cause Mortality Different in HIV-Infected Individuals Compared to General Population? Results from the FHDH-ANRS CO4 CohortQ35705439
Maraviroc Intensification of cART in Patients with Suboptimal Immunological Recovery: A 48-Week, Placebo-Controlled Randomized TrialQ35712284
Role of CD8 T Cell Replicative Senescence in Human Aging and in HIV-mediated ImmunosenescenceQ35720116
Latent and Active Tuberculosis Infection Increase Immune Activation in Individuals Co-Infected with HIVQ35766808
Plasma levels of bacterial DNA correlate with immune activation and the magnitude of immune restoration in persons with antiretroviral-treated HIV infectionQ37309633
HIV replication alters the composition of extrinsic pathway coagulation factors and increases thrombin generationQ37310421
Dyslipidemia and cardiovascular risk in human immunodeficiency virus infectionQ37319195
Metabolic outcomes in a randomized trial of nucleoside, nonnucleoside and protease inhibitor-sparing regimens for initial HIV treatment.Q37338133
Increased acute myocardial infarction rates and cardiovascular risk factors among patients with human immunodeficiency virus diseaseQ37390635
PPARγ signaling and metabolism: the good, the bad and the futureQ37407887
Factors associated with renal dysfunction within an urban HIV-infected cohort in the era of highly active antiretroviral therapyQ37505250
Rosuvastatin treatment reduces markers of monocyte activation in HIV-infected subjects on antiretroviral therapyQ37528422
Th17 cytokines and host-pathogen interactions at the mucosa: dichotomies of help and harmQ37576442
A compositional look at the human gastrointestinal microbiome and immune activation parameters in HIV infected subjectsQ37595511
Hepatic inflammation and progressive liver fibrosis in chronic liver diseaseQ37629675
Hepatic fibrosis and the renin-angiotensin systemQ37763825
Pathogenesis of liver fibrosisQ37809079
Hydroxychloroquine: from malaria to autoimmunityQ37827403
Conventional medical management of inflammatory bowel diseaseQ37870434
Atherosclerosis: current pathogenesis and therapeutic optionsQ37953777
Immunosenescence and HIV.Q38015598
Thiazolidinediones in the treatment of HIV/HAART-associated lipodystrophy syndrome.Q38133959
Metabolic disease in HIV infectionQ38155277
Relationship between CD4 cell count and serious long-term complications among HIV-positive individualsQ38166161
HIV-associated nephropathies: epidemiology, pathology, mechanisms and treatmentQ38357279
Treatment intensification with raltegravir in subjects with sustained HIV-1 viraemia suppression: a randomized 48-week study.Q38476717
Intensification of antiretroviral therapy with raltegravir or addition of hyperimmune bovine colostrum in HIV-infected patients with suboptimal CD4+ T-cell response: a randomized controlled trialQ38484316
Innate immunity against HIV-1 infectionQ38491184
Effect of pioglitazone on HIV-1-related lipodystrophy: a randomized double-blind placebo-controlled trial (ANRS 113).Q39470173
Identifying the target cell in primary simian immunodeficiency virus (SIV) infection: highly activated memory CD4(+) T cells are rapidly eliminated in early SIV infection in vivoQ39588498
Unusual CD4+CD28null T lymphocytes and recurrence of acute coronary eventsQ40166868
Recombinant methionyl human leptin therapy in replacement doses improves insulin resistance and metabolic profile in patients with lipoatrophy and metabolic syndrome induced by the highly active antiretroviral therapyQ40331192
Tissue factor: molecular recognition and cofactor function.Q40447432
CD14 is an acute-phase proteinQ40575802
Sofosbuvir plus ribavirin for treatment of hepatitis C virus in patients co-infected with HIV (PHOTON-2): a multicentre, open-label, non-randomised, phase 3 studyQ41497390
Assessment of chloroquine as a modulator of immune activation to improve CD4 recovery in immune nonresponding HIV-infected patients receiving antiretroviral therapyQ41921243
Comparison of hydroxychloroquine with zidovudine in asymptomatic patients infected with human immunodeficiency virus type 1.Q41927429
Raltegravir intensification shows differing effects on CD8 and CD4 T cells in HIV-infected HAART-suppressed individuals with poor CD4 T-cell recoveryQ41928271
Hydroxychloroquine drastically reduces immune activation in HIV-infected, antiretroviral therapy-treated immunologic nonrespondersQ41932770
Associations between immune depression and cardiovascular events in HIV infectionQ42255667
Improved metabolic profile after switch to darunavir/ritonavir in HIV positive patients previously on protease inhibitor therapyQ42270440
Long-term suppressive combined antiretroviral treatment does not normalize the serum level of soluble CD14.Q42278643
Mortality attributable to smoking among HIV-1-infected individuals: a nationwide, population-based cohort studyQ42282082
Human immunodeficiency virus type 1-related lipoatrophy and lipohypertrophy are associated with serum concentrations of leptinQ45728845
Circulating HIV-specific CD8+ cytotoxic T cells express CD38 and HLA-DR antigens.Q46200764
Effect of cytomegalovirus-induced immune response, self antigen-induced immune response, and microbial translocation on chronic immune activation in successfully treated HIV type 1-infected patients: the ANRS CO3 Aquitaine CohortQ46753948
ColoPlus, a new product based on bovine colostrum, alleviates HIV-associated diarrhoeaQ46948549
European Guidelines on cardiovascular disease prevention in clinical practice (version 2012). The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constitutedQ48527068
The effect of intensification with raltegravir on the HIV-1 reservoir of latently infected memory CD4 T cells in suppressed patients.Q50937169
Premature age-related comorbidities among HIV-infected persons compared with the general population.Q51000618
Ten-year diabetes incidence in 1046 HIV-infected patients started on a combination antiretroviral treatment.Q51388029
Circulating levels of inflammatory markers and cancer risk in the health aging and body composition cohort.Q51509450
Primary care guidelines for the management of persons infected with HIV: 2013 update by the HIV medicine association of the Infectious Diseases Society of America.Q51859231
CD4 cell count and viral load-specific rates of AIDS, non-AIDS and deaths according to current antiretroviral use.Q51873827
Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells.Q51993308
Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis.Q52993523
Mortality in the highly active antiretroviral therapy era: changing causes of death and disease in the HIV outpatient study.Q53608173
Highly active antiretroviral therapy during early HIV infection reverses T-cell activation and maturation abnormalities. Swiss HIV Cohort Study.Q53941835
Association of severe insulin resistance with both loss of limb fat and elevated serum tumor necrosis factor receptor levels in HIV lipodystrophy.Q54026923
Clinical relevance of cytomegalovirus viraemia(*,†).Q54391854
Residual viraemia in HIV-1-infected patients with plasma viral load Q54504612
High-sensitivity C-reactive protein levels fall during statin therapy in HIV-infected patients receiving ritonavir-boosted protease inhibitorsQ56837773
Effect of immunodeficiency, HIV viral load, and antiretroviral therapy on the risk of individual malignancies (FHDH-ANRS CO4): a prospective cohort studyQ56837790
Associations of circulating C-reactive protein and interleukin-6 with cancer risk: findings from two prospective cohorts and a meta-analysisQ57125261
A randomized comparative trial of tenofovir DF or abacavir as replacement for a thymidine analogue in persons with lipoatrophyQ57181107
Projected life expectancy of people with HIV according to timing of diagnosisQ57476832
Immune modulatory effects of cyclooxygenase type 2 inhibitors in HIV patients on combination antiretroviral treatmentQ58123225
Maraviroc Can Improve Lipid Profiles in Dyslipidemic Patients with HIV: Results from the MERIT TrialQ58290838
Maraviroc Intensification of Stable Antiviral Therapy in HIV-1–Infected Patients With Poor Immune RestorationQ59732151
Different biological significance of sCD14 and LPS in HIV-infection: Importance of the immunovirology stage and association with HIV-disease progression markersQ61415686
Mortality in Patients With Successful Initial Response to Highly Active Antiretroviral Therapy Is Still Higher Than in Non-HIV-Infected IndividualsQ63364000
A preparation from bovine colostrum in the treatment of HIV-positive patients with chronic diarrheaQ70610258
Analysis of apoptosis in lymph nodes of HIV-infected persons. Intensity of apoptosis correlates with the general state of activation of the lymphoid tissue and not with stage of disease or viral burdenQ72191747
Coagulation and activation of inflammatory pathways in the development of functional decline and mortality in the elderlyQ73127365
Fibrin D-dimer and coronary heart disease: prospective study and meta-analysisQ73881440
Perturbation of CD4+ and CD8+ T-cell repertoires during progression to AIDS and regulation of the CD4+ repertoire during antiviral therapyQ74165679
T-cell-mediated lysis of endothelial cells in acute coronary syndromesQ77595337
Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderlyQ77769291
C-reactive protein levels, variation in the C-reactive protein gene, and cancer risk: the Rotterdam StudyQ79370345
Probiotics: definition, sources, selection, and usesQ80463721
Impact of highly active antiretroviral therapy on blood pressure in HIV-infected patients. A prospective study in a cohort of naive patientsQ81543046
Antiretroviral medications associated with elevated blood pressure among patients receiving highly active antiretroviral therapyQ83128900
Downregulation of CD38 activation markers by atorvastatin in HIV patients with undetectable viral loadQ83917425
Medicine. Hepatitis C can be cured globally, but at what cost?Q87383411
Once-daily darunavir/ritonavir vs. lopinavir/ritonavir in treatment-naive, HIV-1-infected patients: 96-week analysisQ42623275
Reversibility of lipoatrophy in HIV-infected patients 2 years after switching from a thymidine analogue to abacavir: the MITOX Extension StudyQ42625324
The safety and efficacy of switching stavudine to tenofovir df in combination with lamivudine and efavirenz in hiv-1-infected patients: three-year follow-up after switching therapyQ42638025
Valganciclovir reduces T cell activation in HIV-infected individuals with incomplete CD4+ T cell recovery on antiretroviral therapyQ42720721
Enhanced T cell recovery in HIV-1-infected adults through IL-7 treatmentQ42924252
Persistent microbial translocation and immune activation in HIV-1-infected South Africans receiving combination antiretroviral therapy.Q42970792
Sevelamer decreases systemic inflammation in parallel to a reduction in endotoxemiaQ43112837
HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects.Q43130032
Switch to a raltegravir-based regimen versus continuation of a lopinavir-ritonavir-based regimen in stable HIV-infected patients with suppressed viraemia (SWITCHMRK 1 and 2): two multicentre, double-blind, randomised controlled trialsQ43194317
Durable efficacy and safety of raltegravir versus efavirenz when combined with tenofovir/emtricitabine in treatment-naive HIV-1-infected patients: final 5-year results from STARTMRK.Q43451461
Decreasing mortality and changing patterns of causes of death in the Swiss HIV Cohort StudyQ43552952
Placebo-controlled trial of prednisone in advanced HIV-1 infectionQ43556071
Importance of cytomegalovirus viraemia in risk of disease progression and death in HIV-infected patients receiving highly active antiretroviral therapyQ43564797
A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitorsQ43613003
Prevalence and predictive value of intermittent viremia with combination hiv therapyQ43670221
Treatment of diarrhoea in human immunodeficiency virus-infected patients with immunoglobulins from bovine colostrumQ43686516
Immunologic responses associated with 12 weeks of combination antiretroviral therapy consisting of zidovudine, lamivudine, and ritonavir: results of AIDS Clinical Trials Group Protocol 315.Q44015315
High prevalence of osteonecrosis of the femoral head in HIV-infected adults.Q44047072
A study of the immunology, virology, and safety of prednisone in HIV-1-infected subjects with CD4 cell counts of 200 to 700 mm(-3).Q44355646
Cardiovascular disease risk factors in HIV patients--association with antiretroviral therapy. Results from the DAD studyQ44486385
Risk factors for coronary heart disease in patients treated for human immunodeficiency virus infection compared with the general populationQ44510170
Recovery of mucosal barrier function in ischemic porcine ileum and colon is stimulated by a novel agonist of the ClC-2 chloride channel, lubiprostoneQ44868329
Cirrhosis and hepatocellular carcinoma in HIV-infected veterans with and without the hepatitis C virus: a cohort study, 1992-2001.Q45333318
Sustained virological response to interferon plus ribavirin reduces non-liver-related mortality in patients coinfected with HIV and Hepatitis C virus.Q45357510
Sustained virological response to interferon plus ribavirin reduces liver-related complications and mortality in patients coinfected with human immunodeficiency virus and hepatitis C virusQ45383108
Premature induction of an immunosuppressive regulatory T cell response during acute simian immunodeficiency virus infectionQ45420228
Epstein-Barr virus DNA loads in adult human immunodeficiency virus type 1-infected patients receiving highly active antiretroviral therapyQ45710801
P433issue5
P304page(s)533-549
P577publication date2016-02-25
P1433published inDrugsQ3040094
P1476titleSerious Non-AIDS Events: Therapeutic Targets of Immune Activation and Chronic Inflammation in HIV Infection
P478volume76

Reverse relations

cites work (P2860)
Q90683081CMV seropositivity is associated with increased microbial translocation in people living with HIV and uninfected controls
Q64100143Effect of metformin on the size of the HIV reservoir in non-diabetic ART-treated individuals: single-arm non-randomised Lilac pilot study protocol
Q92360248Evidence for Persistent Monocyte and Immune Dysregulation After Prolonged Viral Suppression Despite Normalization of Monocyte Subsets, sCD14 and sCD163 in HIV-Infected Individuals
Q59792830High Abundance of genus Prevotella in the gut of perinatally HIV-infected children is associated with IP-10 levels despite therapy
Q98237886Immunometabolism and HIV-1 pathogenesis: food for thought
Q47562735Increased CD127+ and decreased CD57+ T cell expression levels in HIV-infected patients on NRTI-sparing regimens
Q90194896Metformin effect on gut microbiota: insights for HIV-related inflammation
Q92188890Monocyte Based Correlates of Immune Activation and Viremia in HIV-Infected Long-Term Non-Progressors
Q54269208Reduced Chronic Lymphocyte Activation following Interferon Alpha Blockade during the Acute Phase of Simian Immunodeficiency Virus Infection in Rhesus Macaques.
Q99609907Repurposing Metformin in Nondiabetic People With HIV: Influence on Weight and Gut Microbiota
Q93010915Specific Activation In Vivo of HIV-1 by a Bromodomain Inhibitor from Monocytic Cells in Humanized Mice under Antiretroviral Therapy
Q93197905The Bacterium Akkermansia muciniphila: A Sentinel for Gut Permeability and Its Relevance to HIV-Related Inflammation
Q38984137The gut microbiome and HIV-1 pathogenesis: a two-way street

Search more.