Research on the Pathological Mechanism and Drug Treatment Mechanism of Depression

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Research on the Pathological Mechanism and Drug Treatment Mechanism of Depression is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.2174/1570159X1304150831120428
P8608Fatcat IDrelease_eg3qge3w3bd3rhvpnsh63gumbm
P932PMC publication ID4790409
P698PubMed publication ID26412071

P2093author name stringGuo-jiang Peng
Jun-sheng Tian
Xiao-xia Gao
Xue-mei Qin
Yu-zhi Zhou
P2860cites workEfficacy and tolerability of Hypericum perforatum in major depressive disorder in comparison with selective serotonin reuptake inhibitors: a meta-analysisQ46231784
Antidepressant-like effect of liquiritin from Glycyrrhiza uralensis in chronic variable stress induced depression model ratsQ46462367
Pharmacopoeia of traditional medicine in VendaQ46809903
Dynamic analysis of the endogenous metabolites in depressed patients treated with TCM formula Xiaoyaosan using urinary (1)H NMR-based metabolomicsQ47583527
Effects of the Chinese traditional prescription Xiaoyaosan decoction on chronic immobilization stress-induced changes in behavior and brain BDNF, TrkB, and NT-3 in ratsQ48097387
A ¹H-NMR plasma metabonomic study of acute and chronic stress models of depression in ratsQ48263021
Amino acid metabolic dysfunction revealed in the prefrontal cortex of a rat model of depressionQ48287388
Selection and dynamic metabolic response of rat biomarkers by metabonomics and multivariate statistical analysis combined with GC-MS.Q48383474
Hereditary Mental Depression and Parkinsonism With Taurine DeficiencyQ48477599
Brain-derived neurotrophic factor conditional knockouts show gender differences in depression-related behaviors.Q48541992
Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression.Q48635095
Decreased serum brain-derived neurotrophic factor levels in major depressed patients.Q48642995
Anti-depressant effects of Xiaoyaosan on rat model of chronic unpredictable mild stress: a plasma metabonomics study based on NMR spectroscopy.Q48713578
Plasma metabonomics as a novel diagnostic approach for major depressive disorder.Q48760949
Antidepressant-like effect of brain-derived neurotrophic factor (BDNF).Q48824073
Metabonomic study on chronic unpredictable mild stress and intervention effects of Xiaoyaosan in rats using gas chromatography coupled with mass spectrometry.Q48835087
Urinary metabonomics study of anti-depressive effect of Chaihu-Shu-Gan-San on an experimental model of depression induced by chronic variable stress in rats.Q48892802
Effect of treatment on serum brain-derived neurotrophic factor levels in depressed patients.Q48943191
INHIBITION OF UPTAKE OF TRITIATED-NORADRENALINE IN THE INTACT RAT BRAIN BY IMIPRAMINE AND STRUCTURALLY RELATED COMPOUNDS.Q51264563
Increased serum IL-6 and IL-1 receptor antagonist concentrations in major depression and treatment resistant depression.Q51996803
The forced swimming test as a model for core and component behavioral effects of antidepressant drugs.Q53801502
Inflammation and coagulation factors in persons >65 years of age with symptoms of depression but without evidence of myocardial ischemia∗∗The opinions and assertions expressed herein are those of the authors and are not to be construed as reflectQ57392445
Reevaluation of the indoleamine hypothesis of depression. Evidence for a reduction of functional activity of central 5-HT systems by antidepressant drugsQ60050321
5-HT and mechanisms of defenceQ60054589
St John's wort for major depressionQ24241294
Tricyclic antidepressant poisoning : cardiovascular toxicityQ28289594
Are antidepressant drugs that combine serotonergic and noradrenergic mechanisms of action more effective than the selective serotonin reuptake inhibitors in treating major depressive disorder? A meta-analysis of studies of newer agentsQ28307397
1H-NMR-based metabonomic studies on the anti-depressant effect of genipin in the chronic unpredictable mild stress rat modelQ28533575
Inflammatory markers in major depression and melancholiaQ30983304
Kava and St. John's Wort: current evidence for use in mood and anxiety disordersQ33483570
Neurotrophins and depressionQ33547892
Major depression and activation of the inflammatory response systemQ33708105
St John's wort for depression: a systematic reviewQ33824593
Genetic epidemiology of major depression: review and meta-analysisQ33919509
The link between childhood trauma and depression: insights from HPA axis studies in humans.Q34012622
Recent advances in the neurobiology of depression.Q34165846
Mechanism of action of St John's wort in depression : what is known?Q34201296
Antidepressant properties of bioactive fractions from the extract of Crocus sativus L.Q34612267
Effect of antidepressant drugs on the depletion of intraneuronal brain 5-hydroxytryptamine stores caused by 4-methyl-alpha-ethyl-meta-tyramineQ34705720
Hyperforin as a possible antidepressant component of hypericum extractsQ34751517
The HPA axis in major depression: classical theories and new developmentsQ34803590
The inflammatory & neurodegenerative (I&ND) hypothesis of depression: leads for future research and new drug developments in depressionQ34904703
The increasing burden of depressionQ35090232
Synaptic and extrasynaptic secretion of serotonin.Q36209130
The HPA axis and perinatal depression: a hypothesis.Q36481597
Identification and validation of urinary metabolite biomarkers for major depressive disorderQ36508139
HPA axis reactivity: a mechanism underlying the associations among 5-HTTLPR, stress, and depressionQ36639224
St. John's wort: role of active compounds for its mechanism of action and efficacyQ36912872
New insights into BDNF function in depression and anxietyQ36921962
Insomnia as a predictor of depression: a meta-analytic evaluation of longitudinal epidemiological studiesQ37837216
Clinical depression and inflammatory risk markers for coronary heart diseaseQ37870585
Depressive disorders and suicide: Epidemiology, risk factors, and burdenQ38073521
Evidence for an immune response in major depression: a review and hypothesisQ40501767
Traditional medicine in Latin America, with particular reference to MexicoQ40933084
The potential role of excessive cortisol induced by HPA hyperfunction in the pathogenesis of depressionQ41086135
Study of plasma metabolic profiling and biomarkers of chronic unpredictable mild stress rats based on gas chromatography/mass spectrometryQ42810492
Metabonomics study of urine and plasma in depression and excess fatigue rats by ultra fast liquid chromatography coupled with ion trap-time of flight mass spectrometryQ43010213
Metabolomics study on the anti-depression effect of xiaoyaosan on rat model of chronic unpredictable mild stressQ43192606
The relation of severity of depressive symptoms to monocyte-associated proinflammatory cytokines and chemokines in apparently healthy men.Q43492519
Pathways linking depression, adiposity, and inflammatory markers in healthy young adultsQ44314276
Antidepressant effect of Chaihu-Shugan-San extract and its constituents in rat models of depressionQ45218680
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectantidepressantQ76560
hypophyseal portal systemQ1531242
mental depressionQ4340209
depressive disorderQ11076418
pituitary-adrenal systemQ67086239
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)514-23
P577publication date2015-01-01
P1433published inCurrent NeuropharmacologyQ20181354
P1476titleResearch on the Pathological Mechanism and Drug Treatment Mechanism of Depression
P478volume13

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cites work (P2860)
Q98224550A Novel Network Pharmacology Strategy to Decode Metabolic Biomarkers and Targets Interactions for Depression
Q91813332Antidepressant Potential of Cinnamic Acids: Mechanisms of Action and Perspectives in Drug Development
Q58554187Blood and urinary metabolomic evidence validating traditional Chinese medicine diagnostic classification of major depressive disorder
Q58775608Cocaine- and Amphetamine-Regulated Transcript (CART) Peptide Plays Critical Role in Psychostimulant-Induced Depression

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