Therapeutic Strategies and New Intervention Points in Chronic Hepatitis Delta Virus Infection

scientific article (publication date: 2015)

Therapeutic Strategies and New Intervention Points in Chronic Hepatitis Delta Virus Infection is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.3390/IJMS160819537
P932PMC publication ID4581312
P698PubMed publication ID26295228
P5875ResearchGate publication ID281812011

P2093author name stringThomas King
Zhimin Guo
P2860cites workHigh affinity of copper(II) towards amoxicillin, apramycin and ristomycin. Effect of these complexes on the catalytic activity of HDV ribozyme.Q46126816
Treatment of chronic delta hepatitis with lamivudine vs lamivudine + interferon vs interferonQ46727946
Safety and efficacy of RNAi therapy for transthyretin amyloidosisQ46836193
Pegylated interferon alpha-2b as monotherapy or in combination with ribavirin in chronic hepatitis delta.Q50575493
Hepatitis delta virusQ54152890
Phase I study of lonafarnib (SCH66336) in combination with trastuzumab plus paclitaxel in Her2/neu overexpressing breast cancer: EORTC study 16023.Q54478541
Efficacy of peginterferon alpha-2b in chronic hepatitis delta: Relevance of quantitative RT-PCR for follow-upQ57782781
Overexpression of clusterin in human hepatocellular carcinomaQ81314820
The large form of ADAR 1 is responsible for enhanced hepatitis delta virus RNA editing in interferon-alpha-stimulated host cellsQ24304329
Dengue virus inhibits alpha interferon signaling by reducing STAT2 expressionQ24522443
RNA-templated replication of hepatitis delta virus: genomic and antigenomic RNAs associate with different nuclear bodiesQ24548934
A single antigenomic open reading frame of the hepatitis delta virus encodes the epitope(s) of both hepatitis delta antigen polypeptides p24 delta and p27 deltaQ24646279
Influence of hepatitis delta virus infection on morbidity and mortality in compensated cirrhosis type B. The European Concerted Action on Viral Hepatitis (Eurohep)Q24670052
Hepatitis delta: epidemiology, diagnosis and management 36 years after discoveryQ26849602
Structural basis of the oligomerization of hepatitis delta antigenQ27764886
Liver Disintegration in the Mouse Embryo Caused by Deficiency in the RNA-editing Enzyme ADAR1Q28184194
Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasuresQ29615028
Pegylated interferon-based treatment in patients with advanced liver disease due to chronic delta hepatitisQ33404425
Modification of small hepatitis delta virus antigen by SUMO proteinQ33558331
Phosphorylation of serine 177 of the small hepatitis delta antigen regulates viral antigenomic RNA replication by interacting with the processive RNA polymerase II.Q33614472
Prevalence, correlates, and viral dynamics of hepatitis delta among injection drug usersQ33654601
Increasing incidence of recent hepatitis D virus infection in HIV-infected patients in an area hyperendemic for hepatitis B virus infection.Q33813200
Long-term therapy of chronic delta hepatitis with peginterferon alfa.Q33904679
Assembly of hepatitis delta virus particlesQ33932270
A whole recombinant yeast-based therapeutic vaccine elicits HBV X, S and Core specific T cells in mice and activates human T cells recognizing epitopes linked to viral clearanceQ33933196
Hepatitis D virus: an updateQ34024141
Varied immunity generated in mice by DNA vaccines with large and small hepatitis delta antigens.Q34227136
Replicative and transcriptional activities of hepatitis B virus in patients coinfected with hepatitis B and hepatitis delta viruses.Q34457758
Catalytic strategies of the hepatitis delta virus ribozymesQ34667466
Combination of DNA prime--adenovirus boost immunization with entecavir elicits sustained control of chronic hepatitis B in the woodchuck modelQ34778476
The hepatitis delta virus RNA genome interacts with the human RNA polymerases I and III.Q34952799
Hepatitis delta virus epigenetically enhances clusterin expression via histone acetylation in human hepatocellular carcinoma cellsQ34957522
Viral hepatitis: past and future of HBV and HDV.Q35045045
Pegylated Interferon α Therapy in Chronic Delta Hepatitis: A One-Center ExperienceQ35267105
Hepatitis D Virus Infection of Mice Expressing Human Sodium Taurocholate Co-transporting PolypeptideQ35526264
Assembly of hepatitis delta virus: particle characterization, including the ability to infect primary human hepatocytesQ35785074
Oral prenylation inhibition with lonafarnib in chronic hepatitis D infection: a proof-of-concept randomised, double-blind, placebo-controlled phase 2A trial.Q36428213
Identification of an intrahepatic transcriptional signature associated with self-limiting infection in the woodchuck model of hepatitis B.Q36476515
Breaking the central dogma by RNA editingQ36559666
Isoprenylation masks a conformational epitope and enhances trans-dominant inhibitory function of the large hepatitis delta antigenQ36633321
Hepatocyte-targeted RNAi therapeutics for the treatment of chronic hepatitis B virus infectionQ36883851
Prime/boost immunization with DNA and adenoviral vectors protects from hepatitis D virus (HDV) infection after simultaneous infection with HDV and woodchuck hepatitis virus.Q36978876
The large form of hepatitis delta antigen is crucial for assembly of hepatitis delta virusQ37597959
Virology of hepatitis D virusQ38039005
Treatment of chronic delta hepatitisQ38039010
Clinical pharmacological properties of mipomersen (Kynamro), a second generation antisense inhibitor of apolipoprotein B.Q38046628
Life cycle and pathogenesis of hepatitis D virus: A reviewQ38177275
Mouse models of hepatitis B and delta virus infectionQ38196163
Strategies to inhibit entry of HBV and HDV into hepatocytes.Q38207387
Current status in the therapy of liver diseasesQ38208508
Pharmacokinetics, biodistribution and cell uptake of antisense oligonucleotidesQ38301148
Hepatitis B and D viruses exploit sodium taurocholate co-transporting polypeptide for species-specific entry into hepatocytes.Q38310253
Proteomic changes in HEK-293 cells induced by hepatitis delta virus replication.Q39139176
Large hepatitis delta antigen activates STAT-3 and NF-κB via oxidative stressQ39281231
Nucleic acid polymers prevent the establishment of duck hepatitis B virus infection in vivoQ39368000
Treatment options for hepatitis delta virus infectionQ39502937
In vivo antiviral efficacy of prenylation inhibitors against hepatitis delta virus.Q39793276
Hepatitis B virus infection initiates with a large surface protein-dependent binding to heparan sulfate proteoglycansQ39823787
Intracellular localization of hepatitis delta virus proteins in the presence and absence of viral RNA accumulation.Q39860676
Hepatitis delta virus inhibits alpha interferon signalingQ39904698
Induction of cytotoxic T lymphocyte responses against hepatitis delta virus antigens which protect against tumor formation in miceQ40778961
Hepatitis Delta co-infection in humanized mice leads to pronounced induction of innate immune responses in comparison to HBV mono-infectionQ41399410
Design of potential siRNA molecules for hepatitis delta virus gene silencingQ41841424
Viral hepatitis. HBV cure--can we pin our hopes on immunotherapy?Q42174019
Safety, tolerability and immunogenicity of GS-4774, a hepatitis B virus-specific therapeutic vaccine, in healthy subjects: a randomized studyQ42204820
Resolution of chronic hepatitis Delta after 1 year of combined therapy with pegylated interferon, tenofovir and emtricitabineQ43242166
Farnesyl transferase inhibitor (lonafarnib) in patients with myelodysplastic syndrome or secondary acute myeloid leukaemia: a phase II studyQ44830085
A novel therapeutic hepatitis B vaccine induces cellular and humoral immune responses and breaks tolerance in hepatitis B virus (HBV) transgenic miceQ45353109
The increasing prevalence of hepatitis delta virus (HDV) infection in South LondonQ45398479
An RNAi therapeutic targeting antithrombin to rebalance the coagulation system and promote hemostasis in hemophilia.Q45874701
P275copyright licenseCreative Commons AttributionQ6905323
P6216copyright statuscopyrightedQ50423863
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectvirusQ808
catalysisQ82264
organic chemistryQ11351
hepatitis delta virusQ1607636
host microbial interactionQ68260314
RNA virus infectious diseaseQ18967413
antiviral agentQ40207875
P304page(s)19537-52
P577publication date2015-08-18
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleTherapeutic Strategies and New Intervention Points in Chronic Hepatitis Delta Virus Infection
P478volume16

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