review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Tomas Ganz | Q15059118 |
Kathryn Michels | Q56488049 | ||
Borna Mehrad | Q41554549 | ||
P2093 | author name string | Elizabeta Nemeth | |
P2860 | cites work | Hepcidin protects against lipopolysaccharide-induced liver injury in a mouse model of obstructive jaundice. | Q54338584 |
Molecular mechanism of hepcidin-mediated ferroportin internalization requires ferroportin lysines, not tyrosines or JAK-STAT. | Q54505590 | ||
Hepcidin regulation by innate immune and infectious stimuli | Q59401841 | ||
C282Y mutation and hepatic iron status in hepatitis C and cryptogenic cirrhosis | Q73191778 | ||
Intraphagosomal Mycobacterium tuberculosis acquires iron from both extracellular transferrin and intracellular iron pools. Impact of interferon-gamma and hemochromatosis | Q78425267 | ||
Hepatitis C, iron status, and disease severity: relationship with HFE mutations | Q78854372 | ||
Hereditary hemochromatosis results in decreased iron acquisition and growth by Mycobacterium tuberculosis within human macrophages | Q79234100 | ||
Increased hepcidin expression and hypoferraemia associated with an acute phase response are not affected by inactivation of HFE | Q80348512 | ||
The origin and spread of the HFE-C282Y haemochromatosis mutation | Q80409591 | ||
Time-course analysis of hepcidin, serum iron, and plasma cytokine levels in humans injected with LPS | Q81734651 | ||
Hepcidin expression and iron transport in alveolar macrophages | Q83221889 | ||
LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity | Q24290410 | ||
Hepcidin, a urinary antimicrobial peptide synthesized in the liver | Q24290609 | ||
Interleukin-6 induces hepcidin expression through STAT3 | Q24296906 | ||
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization | Q24310115 | ||
Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression | Q24316099 | ||
The hemochromatosis proteins HFE, TfR2, and HJV form a membrane-associated protein complex for hepcidin regulation | Q24338877 | ||
Severe iron deficiency anemia in transgenic mice expressing liver hepcidin | Q24536163 | ||
IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin | Q24568204 | ||
Hepcidin mediates transcriptional changes that modulate acute cytokine-induced inflammatory responses in mice | Q24617847 | ||
Iron, anemia and hepcidin in malaria | Q26828803 | ||
Fungal iron availability during deep seated candidiasis is defined by a complex interplay involving systemic and local events | Q27332296 | ||
Hepcidin expression in the liver: relatively low level in patients with chronic hepatitis C | Q27478403 | ||
The solution structure of human hepcidin, a peptide hormone with antimicrobial activity that is involved in iron uptake and hereditary hemochromatosis | Q27639413 | ||
Multicentric origin of hemochromatosis gene (HFE) mutations | Q28139525 | ||
Associations of iron overload in Africa with hepatocellular carcinoma and tuberculosis: Strachan's 1929 thesis revisited. | Q51036431 | ||
Blunted hepcidin response to inflammation in the absence of Hfe and transferrin receptor 2. | Q52607006 | ||
A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload | Q28139987 | ||
Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein | Q28214986 | ||
Identification of erythroferrone as an erythroid regulator of iron metabolism | Q28240988 | ||
HLA haplotype map of river valley populations with hemochromatosis traced through five centuries in Central Sweden | Q28273833 | ||
The serine protease TMPRSS6 is required to sense iron deficiency | Q28278593 | ||
Suppression of hepcidin expression and iron overload mediate Salmonella susceptibility in ankyrin 1 ENU-induced mutant | Q28505375 | ||
Targeted disruption of hepcidin in the liver recapitulates the hemochromatotic phenotype | Q28510894 | ||
Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice | Q28586797 | ||
A mouse model of anemia of inflammation: complex pathogenesis with partial dependence on hepcidin | Q28590264 | ||
Balancing acts: molecular control of mammalian iron metabolism | Q29620380 | ||
The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation | Q29620394 | ||
The battle for iron between bacterial pathogens and their vertebrate hosts | Q33658687 | ||
Iron metabolism in pathogenic bacteria. | Q33920195 | ||
Epidemic pathogenic selection: an explanation for hereditary hemochromatosis? | Q33961191 | ||
Effects of iron overload on the immune system | Q34068469 | ||
Distinct patterns of hepcidin and iron regulation during HIV-1, HBV, and HCV infections | Q34082628 | ||
Low hepcidin accounts for the proinflammatory status associated with iron deficiency. | Q34188665 | ||
BMP type II receptors have redundant roles in the regulation of hepatic hepcidin gene expression and iron metabolism | Q34293026 | ||
HFE gene and hereditary hemochromatosis: a HuGE review. Human Genome Epidemiology | Q34322947 | ||
Host-mediated regulation of superinfection in malaria | Q34356504 | ||
Hepcidin regulation by BMP signaling in macrophages is lipopolysaccharide dependent. | Q34427185 | ||
Silencing airway epithelial cell-derived hepcidin exacerbates sepsis induced acute lung injury | Q34570105 | ||
Iron availability and infection | Q34803576 | ||
Targeting iron acquisition blocks infection with the fungal pathogens Aspergillus fumigatus and Fusarium oxysporum | Q34819468 | ||
Iron levels in hepatocytes and portal tract cells predict progression and outcomes of patients with advanced chronic hepatitis C. | Q34851479 | ||
A strong anti-inflammatory signature revealed by liver transcription profiling of Tmprss6-/- mice. | Q34903557 | ||
Interleukin-10 regulates hepcidin in Plasmodium falciparum malaria | Q35092820 | ||
The IL-6- and lipopolysaccharide-induced transcription of hepcidin in HFE-, transferrin receptor 2-, and beta 2-microglobulin-deficient hepatocytes | Q35316703 | ||
Inflammation-induced hepcidin-25 is associated with the development of anemia in septic patients: an observational study | Q35567161 | ||
Iron deficiency protects against severe Plasmodium falciparum malaria and death in young children | Q35845332 | ||
Hepcidin demonstrates a biphasic association with anemia in acute Plasmodium falciparum malaria | Q36366599 | ||
Iron depletion limits intracellular bacterial growth in macrophages | Q36787471 | ||
The effect of the host's iron status on tuberculosis | Q36816940 | ||
The iron export protein ferroportin 1 is differentially expressed in mouse macrophage populations and is present in the mycobacterial-containing phagosome. | Q36838527 | ||
Association of hemochromatosis with infectious diseases: expanding spectrum | Q36864775 | ||
Survival advantage of the hemochromatosis C282Y mutation | Q37056091 | ||
Reduced serum hepcidin levels in patients with chronic hepatitis C. | Q37387659 | ||
Absence of functional Hfe protects mice from invasive Salmonella enterica serovar Typhimurium infection via induction of lipocalin-2. | Q37398323 | ||
Leishmania-mediated inhibition of iron export promotes parasite replication in macrophages. | Q37534221 | ||
Hepcidin induction by pathogens and pathogen-derived molecules is strongly dependent on interleukin-6 | Q37546397 | ||
Beyond anemia: hepcidin, monocytes and inflammation | Q38073620 | ||
Dual stimulation with bacterial and viral components increases the expression of hepcidin in human monocytes | Q38304822 | ||
Randomised placebo-controlled trial of iron supplementation and malaria chemoprophylaxis for prevention of severe anaemia and malaria in Tanzanian infants | Q39244633 | ||
Bacterial cell wall constituents induce hepcidin expression in macrophages through MyD88 signaling | Q39356682 | ||
Role of Ferroportin in Macrophage-Mediated Immunity | Q39656348 | ||
Bone morphogenetic protein (BMP)-responsive elements located in the proximal and distal hepcidin promoter are critical for its response to HJV/BMP/SMAD. | Q39881846 | ||
Attenuated inflammatory responses in hemochromatosis reveal a role for iron in the regulation of macrophage cytokine translation | Q39953240 | ||
Hepatitis C virus-induced oxidative stress suppresses hepcidin expression through increased histone deacetylase activity | Q39955308 | ||
Expression and localization of hepcidin in macrophages: a role in host defense against tuberculosis. | Q40112013 | ||
The iron efflux protein ferroportin regulates the intracellular growth of Salmonella enterica | Q40290550 | ||
Assessment of urinary concentrations of hepcidin provides novel insight into disturbances in iron homeostasis during malarial infection | Q40404046 | ||
The effects on malaria of treatment of iron-deficiency anaemia with oral iron in Gambian children | Q40777786 | ||
Distinct requirements for Hfe in basal and induced hepcidin levels in iron overload and inflammation. | Q41370453 | ||
Hepcidin-induced hypoferremia is a critical host defense mechanism against the siderophilic bacterium Vibrio vulnificus | Q41543544 | ||
Hepatic hepcidin protects against polymicrobial sepsis in mice by regulating host iron status | Q41723603 | ||
BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism | Q41871982 | ||
Effects of routine prophylactic supplementation with iron and folic acid on admission to hospital and mortality in preschool children in a high malaria transmission setting: community-based, randomised, placebo-controlled trial | Q42170063 | ||
Inverse agonist of estrogen-related receptor γ controls Salmonella typhimurium infection by modulating host iron homeostasis | Q42222690 | ||
TLR4-dependent hepcidin expression by myeloid cells in response to bacterial pathogens | Q42741793 | ||
Increased susceptibility to Mycobacterium avium in hemochromatosis protein HFE-deficient mice. | Q42754682 | ||
Antimicrobial activity of human hepcidin 20 and 25 against clinically relevant bacterial strains: effect of copper and acidic pH. | Q42936287 | ||
Hepatitis C virus core protein compromises iron-induced activation of antioxidants in mice and HepG2 cells | Q42995764 | ||
Hepatitis C virus-induced reactive oxygen species raise hepatic iron level in mice by reducing hepcidin transcription | Q43047877 | ||
Decreased susceptibility to Plasmodium falciparum infection in pregnant women with iron deficiency | Q43944520 | ||
Low-dose daily iron supplementation for 12 months does not increase the prevalence of malarial infection or density of parasites in young Zanzibari children | Q43948407 | ||
Iron supplementation increases prevalence and effects of malaria: report on clinical studies in Papua New Guinea | Q44700727 | ||
Liver hepcidin mRNA correlates with iron stores, but not inflammation, in patients with chronic hepatitis C. | Q45187496 | ||
The effect of hepatitis B virus infection on hepcidin expression in hepatitis B patients | Q45351134 | ||
Iron deficiency and malaria among children living on the coast of Kenya | Q46411719 | ||
Iron deficiency influences the course of malaria in Plasmodium berghei infected mice. | Q47830788 | ||
Plasmodium falciparum infected erythrocytes induce hepcidin (HAMP) mRNA synthesis by peripheral blood mononuclear cells | Q47913673 | ||
A critical role for phagocytosis in resistance to malaria in iron-deficient mice | Q47977032 | ||
Hepcidin is regulated during blood-stage malaria and plays a protective role in malaria infection | Q47994913 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 8 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | infection | Q166231 |
iron-responsive element-binding protein | Q3408230 | ||
membrane protein | Q423042 | ||
infectious disease | Q18123741 | ||
antimicrobial cationic peptides | Q78188513 | ||
P5008 | on focus list of Wikimedia project | ScienceSource | Q55439927 |
P304 | page(s) | e1004998 | |
P577 | publication date | 2015-08-01 | |
2015-08-20 | |||
P1433 | published in | PLOS Pathogens | Q283209 |
P1476 | title | Hepcidin and Host Defense against Infectious Diseases | |
P478 | volume | 11 |