Role of Ferroportin in Macrophage-Mediated Immunity

scientific article published on September 13, 2010

Role of Ferroportin in Macrophage-Mediated Immunity is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/IAI.00498-10
P953full work available at URLhttps://europepmc.org/articles/pmc2981308?pdf=render
http://iai.asm.org/cgi/content/abstract/78/12/5099
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20837712/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20837712/pdf/?tool=EBI
https://europepmc.org/articles/PMC2981308
https://europepmc.org/articles/PMC2981308?pdf=render
https://doi.org/10.1128/iai.00498-10
https://journals.asm.org/doi/pdf/10.1128/IAI.00498-10
P932PMC publication ID2981308
P698PubMed publication ID20837712

P50authorAndreas SandgrenQ43075616
P2093author name stringErin E. Johnson
Marianne Wessling-Resnick
Megan Murray
Bobby J. Cherayil
P2860cites workHaematologicaQ5638209
A novel mammalian iron-regulated protein involved in intracellular iron metabolismQ22253435
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalizationQ24310115
The flatiron mutation in mouse ferroportin acts as a dominant negative to cause ferroportin diseaseQ24678328
Analyzing real-time PCR data by the comparative C(T) methodQ28131831
A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overloadQ28139987
The SLC40 basolateral iron transporter family (IREG1/ferroportin/MTP1)Q28183692
The ferroportin diseaseQ28241948
The iron exporter ferroportin/Slc40a1 is essential for iron homeostasisQ28264540
Strains of Mycobacterium tuberculosis differ in susceptibility to reactive nitrogen intermediates in vitroQ28369007
Nitric oxide and macrophage functionQ29615327
Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophagesQ29617356
Balancing acts: molecular control of mammalian iron metabolismQ29620380
The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammationQ29620394
The hereditary hemochromatosis gene (HFE): a MHC class I-like gene that functions in the regulation of iron homeostasisQ33784079
Human mutation D157G in ferroportin leads to hepcidin-independent binding of Jak2 and ferroportin down-regulationQ33788725
Iron release from macrophages after erythrophagocytosis is up-regulated by ferroportin 1 overexpression and down-regulated by hepcidinQ33818360
The molecular basis of ferroportin-linked hemochromatosisQ33863312
Iron and Mycobacterium tuberculosis infectionQ34134803
Iron and microbial infectionQ34650077
Iron imports. IV. Hepcidin and regulation of body iron metabolismQ34651570
Role of the NF-kappaB signaling pathway and kappaB cis-regulatory elements on the IRF-1 and iNOS promoter regions in mycobacterial lipoarabinomannan induction of nitric oxideQ34714207
Iron metabolism in the reticuloendothelial systemQ35086735
Mycobacterium tuberculosis gene expression in macrophagesQ35145725
iNOS-mediated nitric oxide production and its regulationQ35789162
Slc11a1 limits intracellular growth of Salmonella enterica sv. Typhimurium by promoting macrophage immune effector functions and impairing bacterial iron acquisition.Q36305784
Iron overload due to mutations in ferroportin.Q36376662
Hepcidin--a peptide hormone at the interface of innate immunity and iron metabolism.Q36566212
Iron homeostasisQ36609733
Iron depletion limits intracellular bacterial growth in macrophagesQ36787471
Mechanisms involved in mycobacterial growth inhibition by gamma interferon-activated bone marrow macrophages: role of reactive nitrogen intermediatesQ36968357
Hepcidin-induced internalization of ferroportin requires binding and cooperative interaction with Jak2.Q37129387
Specific iron chelators determine the route of ferritin degradationQ37420521
Ferroportin-mediated mobilization of ferritin iron precedes ferritin degradation by the proteasomeQ39121778
Attenuated inflammatory responses in hemochromatosis reveal a role for iron in the regulation of macrophage cytokine translationQ39953240
Interferon-gamma limits the availability of iron for intramacrophage Salmonella typhimurium.Q39968051
Kupffer cells modulate iron homeostasis in mice via regulation of hepcidin expressionQ39975948
Expression and localization of hepcidin in macrophages: a role in host defense against tuberculosis.Q40112013
The iron efflux protein ferroportin regulates the intracellular growth of Salmonella entericaQ40290550
Intracellular labile iron pools as direct targets of iron chelators: a fluorescence study of chelator action in living cellsQ40397528
Iron regulates nitric oxide synthase activity by controlling nuclear transcriptionQ41447238
Aminoguanidine, a novel inhibitor of nitric oxide formation, prevents diabetic vascular dysfunctionQ41629495
Iron loading and erythrophagocytosis increase ferroportin 1 (FPN1) expression in J774 macrophages.Q42445804
TLR4-dependent hepcidin expression by myeloid cells in response to bacterial pathogensQ42741793
Molecular and clinical correlates in iron overload associated with mutations in ferroportin.Q43082361
TNF-alpha controls intracellular mycobacterial growth by both inducible nitric oxide synthase-dependent and inducible nitric oxide synthase-independent pathwaysQ43612840
Serum ferritin is derived primarily from macrophages through a nonclassical secretory pathway.Q46645329
The co-ordinated regulation of iron homeostasis in murine macrophages limits the availability of iron for intracellular Salmonella typhimuriumQ50072262
Mycobacterium tuberculosis infects dendritic cells with high frequency and impairs their function in vivo.Q50671032
Associations of iron overload in Africa with hepatocellular carcinoma and tuberculosis: Strachan's 1929 thesis revisited.Q51036431
Effect of iron on the growth and siderophore production of mycobacteriaQ72691121
Association of pulmonary tuberculosis with increased dietary ironQ74442113
Differential potentiation of anti-mycobacterial activity and reactive nitrogen intermediate-producing ability of murine peritoneal macrophages activated by interferon-gamma (IFN-gamma) and tumour necrosis factor-alpha (TNF-alpha)Q74497740
The transferrin receptor binding site on HFE, the class I MHC-related protein mutated in hereditary hemochromatosisQ77884769
Hereditary hemochromatosis results in decreased iron acquisition and growth by Mycobacterium tuberculosis within human macrophagesQ79234100
Hereditary hemochromatosisQ80064354
The effect of iron on the expression of cytokines in macrophages infected with Mycobacterium tuberculosisQ80590388
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectmacrophageQ184204
P304page(s)5099-5106
P577publication date2010-09-13
P1433published inInfection and ImmunityQ6029193
P1476titleRole of ferroportin in macrophage-mediated immunity
Role of Ferroportin in Macrophage-Mediated Immunity
P478volume78

Reverse relations

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