Hepcidin deficiency and iron deficiency do not alter tuberculosis susceptibility in a murine M.tb infection model.

scientific article published on 11 January 2018

Hepcidin deficiency and iron deficiency do not alter tuberculosis susceptibility in a murine M.tb infection model. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PONE.0191038
P932PMC publication ID5764373
P698PubMed publication ID29324800

P50authorPei Jin LimQ63637213
Hal DrakesmithQ89851489
P2093author name stringHelen McShane
Sophie Vaulont
Lisa Stockdale
Elena Stylianou
Nawamin Pinpathomrat
Rachel Harrington-Kandt
Lucy A Eddowes
Marta Ulaszewska
Janet Pasricha
Naomi Bull
Yulia Beglov
P2860cites workHepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalizationQ24310115
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The iron exporter ferroportin/Slc40a1 is essential for iron homeostasisQ28264540
Lack of the bone morphogenetic protein BMP6 induces massive iron overloadQ28510138
Targeted disruption of the hepcidin 1 gene results in severe hemochromatosisQ28588832
Iron- and Hepcidin-Independent Downregulation of the Iron Exporter Ferroportin in Macrophages during Salmonella InfectionQ33619541
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Iron Deficiency Impairs Intra-Hepatic Lymphocyte Mediated Immune ResponseQ35750087
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Relationship Between Blood Concentrations of Hepcidin and Anemia Severity, Mycobacterial Burden, and Mortality Among Patients With HIV-Associated TuberculosisQ36365296
The effect of the host's iron status on tuberculosisQ36816940
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Mycobacterium tuberculosis components stimulate production of the antimicrobial peptide hepcidin.Q53254864
Mycobacteria-induced anaemia revisited: A molecular approach reveals the involvement of NRAMP1 and lipocalin-2, but not of hepcidinQ57617782
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Endogenous hepcidin and its agonist mediate resistance to selected infections by clearing non-transferrin-bound iron.Q39488378
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The iron efflux protein ferroportin regulates the intracellular growth of Salmonella entericaQ40290550
Entry of Mycobacterium tuberculosis into mononuclear phagocytesQ41100721
Iron, anemia, and infectionQ41510673
Hepcidin-induced hypoferremia is a critical host defense mechanism against the siderophilic bacterium Vibrio vulnificusQ41543544
BMP6 is a key endogenous regulator of hepcidin expression and iron metabolismQ41871982
Correction of the iron overload defect in beta-2-microglobulin knockout mice by lactoferrin abolishes their increased susceptibility to tuberculosisQ42048353
Inverse agonist of estrogen-related receptor γ controls Salmonella typhimurium infection by modulating host iron homeostasisQ42222690
TLR4-dependent hepcidin expression by myeloid cells in response to bacterial pathogensQ42741793
Thiol-derivatized minihepcidins retain biological activity.Q43134488
Mortality in HIV infection is independently predicted by host iron status and SLC11A1 and HP genotypes, with new evidence of a gene-nutrient interactionQ43419711
Role of iron in the pathogenesis of Mycobacterium avium infection in miceQ44887242
Pulmonary Iron Homeostasis in Hepcidin Knockout Mice.Q47096230
The co-ordinated regulation of iron homeostasis in murine macrophages limits the availability of iron for intracellular Salmonella typhimuriumQ50072262
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)e0191038
P577publication date2018-01-11
P1433published inPLOS OneQ564954
P1476titleHepcidin deficiency and iron deficiency do not alter tuberculosis susceptibility in a murine M.tb infection model
P478volume13