Interferon-gamma limits the availability of iron for intramacrophage Salmonella typhimurium.

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Interferon-gamma limits the availability of iron for intramacrophage Salmonella typhimurium. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/EJI.200738056
P698PubMed publication ID18581323
P5875ResearchGate publication ID5273478

P50authorGuenter WeissQ42254473
Manfred NairzQ56816089
P2093author name stringPeter Brunner
Heribert Talasz
Klaus Hantke
Gernot Fritsche
P2860cites workCa2+ channel blockers reverse iron overload by a new mechanism via divalent metal transporter-1Q24296806
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalizationQ24310115
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The putative iron transport system SitABCD encoded on SPI1 is required for full virulence of Salmonella typhimurium.Q40625112
Regulatory interactions between iron and nitric oxide metabolism for immune defense against Plasmodium falciparum infection.Q40813924
Effects of interferon-gamma and lipopolysaccharide on macrophage iron metabolism are mediated by nitric oxide-induced degradation of iron regulatory protein 2.Q40897847
Nitric oxide inhibits the degradation of IRP2.Q41037556
Functional requirement of the hypoxia-responsive element in the activation of the inducible nitric oxide synthase promoter by the iron chelator desferrioxamineQ41110961
Iron regulates nitric oxide synthase activity by controlling nuclear transcriptionQ41447238
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Structure of the Shigella dysenteriae haem transport locus and its phylogenetic distribution in enteric bacteriaQ42681729
Role of IL-10 for induction of anemia during inflammationQ44092330
Pathways for the regulation of interferon-gamma-inducible genes by iron in human monocytic cells.Q44529298
Oxygen and iron regulation of iron regulatory protein 2.Q44530905
Effect of iron treatment on circulating cytokine levels in ESRD patients receiving recombinant human erythropoietinQ44797776
Biosynthesis and IroC-dependent export of the siderophore salmochelin are essential for virulence of Salmonella enterica serovar TyphimuriumQ46808987
Dysregulated monocyte iron homeostasis and erythropoietin formation in patients with anemia of chronic diseaseQ46909992
Duodenal HFE expression and hepcidin levels determine body iron homeostasis: modulation by genetic diversity and dietary iron availabilityQ47404090
The co-ordinated regulation of iron homeostasis in murine macrophages limits the availability of iron for intracellular Salmonella typhimuriumQ50072262
Divergent role for TNF-alpha in IFN-gamma-induced killing of Toxoplasma gondii and Salmonella typhimurium contributes to selective susceptibility of patients with partial IFN-gamma receptor 1 deficiencyQ50107286
Intracellular replication of Salmonella typhimurium strains in specific subsets of splenic macrophages in vivo.Q50113387
Effect of murine recombinant interferon-gamma in the protection of mice against Salmonella.Q50467195
Pathways for the regulation of body iron homeostasis in response to experimental iron overload.Q54650040
Autocrine formation of hepcidin induces iron retention in human monocytesQ58876413
Intraphagosomal Mycobacterium tuberculosis acquires iron from both extracellular transferrin and intracellular iron pools. Impact of interferon-gamma and hemochromatosisQ78425267
Minute numbers of contaminant CD8+ T cells or CD11b+CD11c+ NK cells are the source of IFN-gamma in IL-12/IL-18-stimulated mouse macrophage populationsQ80597094
Siderophore biosynthesis but not reductive iron assimilation is essential for Aspergillus fumigatus virulenceQ24647631
The neutrophil lipocalin NGAL is a bacteriostatic agent that interferes with siderophore-mediated iron acquisitionQ27640027
A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulationQ28140006
An iron delivery pathway mediated by a lipocalinQ28216116
Association of the transferrin receptor in human placenta with HFE, the protein defective in hereditary hemochromatosisQ28254820
A cell-surface receptor for lipocalin 24p3 selectively mediates apoptosis and iron uptakeQ28587213
Mammalian tissue oxygen levels modulate iron-regulatory protein activities in vivoQ28591638
Lipocalin 2-deficient mice exhibit increased sensitivity to Escherichia coli infection but not to ischemia-reperfusion injuryQ28591880
Functional diversity of helper T lymphocytesQ29619415
Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating ironQ29619561
The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammationQ29620394
Cytoplasmic protein binds in vitro to a highly conserved sequence in the 5' untranslated region of ferritin heavy- and light-subunit mRNAsQ33563194
The role of iron in protozoan and fungal infectious diseasesQ33666541
Iron release from macrophages after erythrophagocytosis is up-regulated by ferroportin 1 overexpression and down-regulated by hepcidinQ33818360
Heme oxygenase: colors of defense against cellular stressQ34081677
Iron and metal regulation in bacteriaQ34205005
Iron and immunity: a double-edged sword.Q34557043
Interferon gamma-activated human monocytes downregulate transferrin receptors and inhibit the intracellular multiplication of Legionella pneumophila by limiting the availability of ironQ34571751
Iron and microbial infectionQ34650077
Genetics, cytokines and human infectious disease: lessons from weakly pathogenic mycobacteria and salmonellaeQ34805799
Salmochelins, siderophores of Salmonella enterica and uropathogenic Escherichia coli strains, are recognized by the outer membrane receptor IroNQ34915244
Role of receptor proteins for enterobactin and 2,3-dihydroxybenzoylserine in virulence of Salmonella entericaQ34940802
The housekeeping dipeptide permease is the Escherichia coli heme transporter and functions with two optional peptide binding proteinsQ35036520
The pathogen-associated iroA gene cluster mediates bacterial evasion of lipocalin 2.Q35133896
Modification of iron regulation by the inflammatory response.Q36057894
Antimicrobial actions of the NADPH phagocyte oxidase and inducible nitric oxide synthase in experimental salmonellosis. I. Effects on microbial killing by activated peritoneal macrophages in vitroQ36368785
Murine salmonellosis studied by confocal microscopy: Salmonella typhimurium resides intracellularly inside macrophages and exerts a cytotoxic effect on phagocytes in vivo.Q36380558
Molecular and clinical aspects of iron homeostasis: From anemia to hemochromatosis.Q36587705
Heme oxygenase 1 is required for mammalian iron reutilizationQ36601831
Intracellular replication is essential for the virulence of Salmonella typhimuriumQ37650583
Translational regulation via iron-responsive elements by the nitric oxide/NO-synthase pathwayQ38316713
Cytokine-mediated regulation of iron transport in human monocytic cellsQ38358858
Gamma interferon enhances internalization and early nonoxidative killing of Salmonella enterica serovar Typhimurium by human macrophages and modifies cytokine responses.Q39029194
Acquisition of Mn(II) in addition to Fe(II) is required for full virulence of Salmonella enterica serovar TyphimuriumQ39663606
Induction of antimicrobial pathways during early-phase immune response to Salmonella spp. in murine macrophages: gamma interferon (IFN-gamma) and upregulation of IFN-gamma receptor alpha expression are required for NADPH phagocytic oxidase gp91-stimQ39792425
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectSalmonella TyphimuriumQ166491
P304page(s)1923-1936
P577publication date2008-07-01
P1433published inEuropean Journal of ImmunologyQ5412727
P1476titleInterferon-gamma limits the availability of iron for intramacrophage Salmonella typhimurium
P478volume38

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