Intracellular replication is essential for the virulence of Salmonella typhimurium

scientific article published on December 15, 1991

Intracellular replication is essential for the virulence of Salmonella typhimurium is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode1991PNAS...8811470L
P356DOI10.1073/PNAS.88.24.11470
P953full work available at URLhttps://europepmc.org/articles/PMC53157
https://europepmc.org/articles/PMC53157?pdf=render
https://pnas.org/doi/pdf/10.1073/pnas.88.24.11470
P932PMC publication ID53157
P698PubMed publication ID1763061
P5875ResearchGate publication ID21392852

P2093author name stringK. Y. Leung
B. B. Finlay
P2860cites workBactericidal and bacteriolytic activity of serum against gram-negative bacteriaQ33627395
Intracellular methicillin selection of Listeria monocytogenes mutants unable to replicate in a macrophage cell lineQ34291689
Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulentQ35617117
Penetration of Salmonella through a polarized Madin-Darby canine kidney epithelial cell monolayerQ36219136
Phosphate starvation regulon of Salmonella typhimuriumQ36285227
Invasion and replication of Salmonella typhimurium in animal cells.Q36976906
Pathogenesis and immunity in murine salmonellosisQ37055869
Comparative biology of intracellular parasitismQ37061907
Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccinesQ39513114
Auxotrophic Salmonella typhi as live vaccineQ39649722
The effects of biochemical mutation on the virulence of Bacterium typhosum: the virulence of mutantsQ39970330
The effects of biochemical mutation on the virulence of Bacterium typhosum; the loss of virulence of certain mutantsQ39970590
Dissociation between results of in vitro and in vivo antibiotic susceptibility tests for some strains of Pseudomonas aeruginosaQ40943063
Division and Death Rates of Salmonella typhimurium Inside Macrophages: Use of Penicillin as a ProbeQ41036610
Comparison of the invasion strategies used by Salmonella cholerae-suis, Shigella flexneri and Yersinia enterocolitica to enter cultured animal cells: endosome acidification is not required for bacterial invasion or intracellular replicationQ41516620
Characterization of a Salmonella choleraesuis mutant that cannot multiply within epithelial cellsQ41676439
Salmonella interactions with polarized human intestinal Caco-2 epithelial cellsQ41715988
Toxoplasma gondii: fusion competence of parasitophorous vacuoles in Fc receptor-transfected fibroblastsQ41725157
Identification of two strains of MDCK cells which resemble separate nephron tubule segmentsQ42445987
Identification of a T cell hybridoma that produces large quantities of macrophage-activating factorQ42936274
Transitory cis complementation: a method for providing transposition functions to defective transposons.Q42960575
Fine structure of the malaria parasite Plasmodium lophurae developing extracellularly in vitroQ43792343
Salmonella typhimurium aroA mutants as carriers of the Escherichia coli heat-labile enterotoxin B subunit to the murine secretory and systemic immune systemsQ44701798
Identification and characterization of TnphoA mutants of Salmonella that are unable to pass through a polarized MDCK epithelial cell monolayerQ46076466
A Salmonella locus that controls resistance to microbicidal proteins from phagocytic cellsQ50195971
Iron-Binding Catechols and Virulence in Escherichia coli.Q55041735
Feeding mechanisms in extracellular Babesia microti and Plasmodium lophuraeQ64973713
P433issue24
P407language of work or nameEnglishQ1860
P921main subjectSalmonella TyphimuriumQ166491
P304page(s)11470-11474
P577publication date1991-12-01
1991-12-15
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleIntracellular replication is essential for the virulence of Salmonella typhimurium
P478volume88

Reverse relations

cites work (P2860)
Q588278427.2 Genetic Approaches to the Study of Pathogenic Salmonellae
Q33346284A Francisella tularensis Schu S4 purine auxotroph is highly attenuated in mice but offers limited protection against homologous intranasal challenge
Q35606490Acid shock induction of RpoS is mediated by the mouse virulence gene mviA of Salmonella typhimurium
Q39663606Acquisition of Mn(II) in addition to Fe(II) is required for full virulence of Salmonella enterica serovar Typhimurium
Q40398663Activation of murine dendritic cells and macrophages induced by Salmonella enterica serovar Typhimurium
Q40853586Aggregation of host endosomes by Salmonella requires SPI2 translocation of SseFG and involves SpvR and the fms-aroE intragenic region
Q34002323Analysis of virulence of clinical isolates of Salmonella enteritidis in vivo and in vitro
Q33986792Antagonistic activity of Lactobacillus acidophilus LB against intracellular Salmonella enterica serovar Typhimurium infecting human enterocyte-like Caco-2/TC-7 cells
Q37196907Application of an indirect immunofluorescent staining method for detection of Salmonella enteritidis in paraffin slices and antigen location in infected duck tissues
Q28487409Attenuation of and protection induced by a leucine auxotroph of Mycobacterium tuberculosis
Q36888904Attenuation, persistence, and vaccine potential of an Edwardsiella ictaluri purA mutant.
Q44075820Bacillus cereus var. Toyoi modulates the immune reaction and reduces the occurrence of diarrhea in piglets challenged with Salmonella Typhimurium DT104.
Q34280924Bacteria-mediated transfer of eukaryotic expression plasmids into mammalian host cells
Q47557117Bacterial pathogen emergence required more than direct contact with a novel passerine host
Q39846670Beta-lactones decrease the intracellular virulence of Listeria monocytogenes in macrophages
Q33594641Biological cost of AmpC production for Salmonella enterica serotype Typhimurium
Q28473899Carbon metabolism of enterobacterial human pathogens growing in epithelial colorectal adenocarcinoma (Caco-2) cells
Q37746934Carbon metabolism of intracellular bacterial pathogens and possible links to virulence
Q34006100Characterization of auxotrophic mutants of Mycobacterium tuberculosis and their potential as vaccine candidates
Q39509638Characterization of candidate live oral Salmonella typhi vaccine strains harboring defined mutations in aroA, aroC, and htrA.
Q28548489Characterization of the Invasive, Multidrug Resistant Non-typhoidal Salmonella Strain D23580 in a Murine Model of Infection
Q39912972Citrobacter koseriBrain Abscess in the Neonatal Rat: Survival and Replication within Human and Rat Macrophages
Q42625047Classical labeling of bacterial pathogens according to their lifestyle in the host: inconsistencies and alternatives
Q24643808Common themes in microbial pathogenicity revisited
Q34975711Construction and characterization of an attenuated purine auxotroph in a Francisella tularensis live vaccine strain
Q41337931Contrasting regulation of macrophage iron homeostasis in response to infection with Listeria monocytogenes depending on localization of bacteria.
Q35528349Contribution of TonB- and Feo-mediated iron uptake to growth of Salmonella typhimurium in the mouse
Q35012637Contribution of proton-translocating proteins to the virulence of Salmonella enterica serovars Typhimurium, Gallinarum, and Dublin in chickens and mice.
Q35657182DNA adenine methylase mutants of Salmonella typhimurium show defects in protein secretion, cell invasion, and M cell cytotoxicity
Q40188676DNA-based diagnostic tests for Salmonella species targeting agfA, the structural gene for thin, aggregative fimbriae.
Q35567777Decreased intracellular survival of an fkpA mutant of Salmonella typhimurium Copenhagen
Q35272629Delineation of upstream signaling events in the salmonella pathogenicity island 2 transcriptional activation pathway.
Q40699610Differential accumulation of Salmonella[Cu, Zn] superoxide dismutases SodCI and SodCII in intracellular bacteria: correlation with their relative contribution to pathogenicity
Q44354916Differential effects of invasion by and phagocytosis of Salmonella typhimurium on apoptosis in human macrophages: potential role of Rho-GTPases and Akt.
Q39519935Disruption of the genes for ClpXP protease in Salmonella enterica serovar Typhimurium results in persistent infection in mice, and development of persistence requires endogenous gamma interferon and tumor necrosis factor alpha
Q40046693During infection of epithelial cells Salmonella enterica serovar Typhimurium undergoes a time-dependent transcriptional adaptation that results in simultaneous expression of three type 3 secretion systems
Q30524361Dynamics of Salmonella infection of macrophages at the single cell level.
Q41140854Dynamics of growth and death within a Salmonella typhimurium population during infection of macrophages
Q37224019Early immune response following Salmonella enterica subspecies enterica serovar Typhimurium infection in porcine jejunal gut loops
Q40269722Effects of multiplicity of infection, bacterial protein synthesis, and growth phase on adhesion to and invasion of human cell lines by Salmonella typhimurium.
Q39501607Eha, a regulator of Edwardsiella tarda, required for resistance to oxidative stress in macrophages
Q36730524Five Listeria monocytogenes genes preferentially expressed in infected mammalian cells: plcA, purH, purD, pyrE and an arginine ABC transporter gene, arpJ.
Q28487031Functional demonstration of reverse transsulfuration in the Mycobacterium tuberculosis complex reveals that methionine is the preferred sulfur source for pathogenic Mycobacteria
Q35473782Gamma interferon and interleukin-10 gene expression in innately susceptible and resistant mice during the early phase of Salmonella typhimurium infection
Q40259195Generating tetracycline-inducible auxotrophy in Escherichia coli and Salmonella enterica serovar Typhimurium by using an insertion element and a hyperactive transposase
Q37747139Genetic and Dietary Iron Overload Differentially Affect the Course of Salmonella Typhimurium Infection
Q29547599Genetic requirements for mycobacterial survival during infection
Q41130212Gp96 rich lysate as a vaccine candidate against infection with Salmonella typhimurium
Q40004886Heme oxygenase 1 controls early innate immune response of macrophages to Salmonella Typhimurium infection.
Q34014256Host factors that influence the behaviour of bacterial pathogens in vivo
Q37729244Humanized mice are susceptible to Salmonella typhi infection
Q40596753Identification of Salmonella typhi genes expressed within macrophages by selective capture of transcribed sequences (SCOTS).
Q90710505Identification of Vibrio cholerae methionine acquisition systems elucidates methionine availability in the arthropod intestine
Q41207631Identification of a Salmonella virulence gene required for formation of filamentous structures containing lysosomal membrane glycoproteins within epithelial cells
Q54580636Identification of a bacterial inhibitor of protein kinases. Mechanism and role in host cell invasion.
Q33756680Identification of three highly attenuated Salmonella typhimurium mutants that are more immunogenic and protective in mice than a prototypical aroA mutant
Q38955988Improved cytotoxic effects of Salmonella-producing cytosine deaminase in tumour cells.
Q35852932In Vivo-Expressed Proteins of Virulent Leptospira interrogans Serovar Autumnalis N2 Elicit Strong IgM Responses of Value in Conclusive Diagnosis
Q35394135In vivo growth characteristics of leucine and methionine auxotrophic mutants of Mycobacterium bovis BCG generated by transposon mutagenesis.
Q33999966Influence of the Salmonella typhimurium pathogenicity island 2 type III secretion system on bacterial growth in the mouse.
Q36446838Intact purine biosynthesis pathways are required for wild-type virulence of Brucella abortus 2308 in the BALB/c mouse model
Q40478945Interactions Between Salmonella Typhimurium, Enteropathogenic Escherichia Coli (EPEC), and Host Epithelial Cells
Q41859338Intercellular spreading of Porphyromonas gingivalis infection in primary gingival epithelial cells
Q39968051Interferon-gamma limits the availability of iron for intramacrophage Salmonella typhimurium.
Q35028632Internalization of Escherichia coli o157:h7 by bovine rectal epithelial cells
Q33607802Intracytoplasmic growth and virulence of Listeria monocytogenes auxotrophic mutants.
Q39511730Invasive ability of an Escherichia coli strain isolated from the ileal mucosa of a patient with Crohn's disease
Q34955583Klebsiella pneumoniae translocates across the intestinal epithelium via Rho GTPase- and phosphatidylinositol 3-kinase/Akt-dependent cell invasion
Q39824942Leucine auxotrophy restricts growth of Mycobacterium bovis BCG in macrophages.
Q27976514Macrophage-dependent induction of the Salmonella pathogenicity island 2 type III secretion system and its role in intracellular survival
Q55448576Methionine biosynthesis and transport are functionally redundant for the growth and virulence of Salmonella Typhimurium.
Q41017047MglA and MglB are required for the intramacrophage growth of Francisella novicida
Q39513368Microtubules are associated with intracellular movement and spread of the periodontopathogen Actinobacillus actinomycetemcomitans
Q41489386Models of invasion of enteric and periodontal pathogens into epithelial cells: a comparative analysis
Q39741860Molecular characterization of the prototrophic Salmonella mutants defective for intraepithelial replication
Q40557545Morphologic evaluation of the pathogenesis of bacterial enteric infections
Q33797653Murein lipoprotein is a critical outer membrane component involved in Salmonella enterica serovar typhimurium systemic infection
Q36380558Murine salmonellosis studied by confocal microscopy: Salmonella typhimurium resides intracellularly inside macrophages and exerts a cytotoxic effect on phagocytes in vivo.
Q35164461Nifedipine affects the course of Salmonella enterica serovar Typhimurium infection by modulating macrophage iron homeostasis
Q50040628Nitrosative stress causes amino acid auxotrophy in hmp mutant Salmonella Typhimurium
Q27303201Novel tools to analyze the function of Salmonella effectors show that SvpB ectopic expression induces cell cycle arrest in tumor cells
Q30841127Nucleotide biosynthesis is critical for growth of bacteria in human blood
Q39498843OmpR regulates the two-component system SsrA-ssrB in Salmonella pathogenicity island 2.
Q34009030Opsonized virulent Edwardsiella tarda strains are able to adhere to and survive and replicate within fish phagocytes but fail to stimulate reactive oxygen intermediates
Q34697874Parallel exploitation of diverse host nutrients enhances Salmonella virulence.
Q33590091Pathogen proliferation governs the magnitude but compromises the function of CD8 T cells
Q37264192Pathogenesis of human enterovirulent bacteria: lessons from cultured, fully differentiated human colon cancer cell lines
Q39920918Porcine in vitro and in vivo models to assess the virulence of Salmonella enterica serovar Typhimurium for pigs
Q39824248Porphyromonas gingivalis FDC381 multiplies and persists within human oral epithelial cells in vitro.
Q27663668PoxA, YjeK, and Elongation Factor P Coordinately Modulate Virulence and Drug Resistance in Salmonella enterica
Q24805942Production of diamino propionic acid ammonia lyase by a new strain of Salmonella typhimurium PU011.
Q37547007Purine Biosynthesis Metabolically Constrains Intracellular Survival of Uropathogenic Escherichia coli
Q50047320Quantitative studies of the distribution pattern for Salmonella Enteritidis in the internal organs of chicken after oral challenge by a real-time PCR.
Q37196910Quantitative studies of the regular distribution pattern for Salmonella enteritidis in the internal organs of mice after oral challenge by a specific real-time polymerase chain reaction
Q33955457Questions about the behaviour of bacterial pathogens in vivo
Q39827077Release of lipopolysaccharide from intracellular compartments containing Salmonella typhimurium to vesicles of the host epithelial cell.
Q40269189Role of acid tolerance response genes in Salmonella typhimurium virulence
Q34105911Role of the RecBCD recombination pathway in Salmonella virulence.
Q33765193S. Typhimurium sseJ gene decreases the S. Typhi cytotoxicity toward cultured epithelial cells
Q41785768Salmonella enterica serovar Typhimurium pathogenicity island 2 is necessary for complete virulence in a mouse model of infectious enterocolitis
Q28766733Salmonella enterica serovar Typhimurium periplasmic superoxide dismutase SodCI is a member of the PhoPQ regulon and is induced in macrophages
Q39522566Salmonella enterica serovar Typhimurium response involved in attenuation of pathogen intracellular proliferation
Q33826144Salmonella enterica serovar Typhimurium-induced placental inflammation and not bacterial burden correlates with pathology and fatal maternal disease
Q36660048Salmonella induces the formation of filamentous structures containing lysosomal membrane glycoproteins in epithelial cells
Q34469834Salmonella intracellular proliferation: where, when and how?
Q40375812Salmonella invasion of nonphagocytic cells induces formation of macropinosomes in the host cell
Q40672000Salmonella typhimurium SifA effector protein requires its membrane-anchoring C-terminal hexapeptide for its biological function
Q34002348Salmonella typhimurium virulence genes are induced upon bacterial invasion into phagocytic and nonphagocytic cells
Q33573164Selectively reduced intracellular proliferation of Salmonella enterica serovar typhimurium within APCs limits antigen presentation and development of a rapid CD8 T cell response
Q47805424Survival of Salmonella serovar Typhimurium inside porcine monocytes is associated with complement binding and suppression of the production of reactive oxygen species
Q30499020TLR signaling is required for Salmonella typhimurium virulence
Q36575276The DnaK/DnaJ chaperone machinery of Salmonella enterica serovar Typhimurium is essential for invasion of epithelial cells and survival within macrophages, leading to systemic infection
Q37074020The In Vitro Redundant Enzymes PurN and PurT Are Both Essential for Systemic Infection of Mice in Salmonella enterica Serovar Typhimurium
Q47854702The NRAMP proteins of Salmonella typhimurium and Escherichia coli are selective manganese transporters involved in the response to reactive oxygen
Q41834286The Salmonella enterica serovar Typhi tsx gene, encoding a nucleoside-specific porin, is essential for prototrophic growth in the absence of nucleosides
Q37053194The Salmonellae PhoQ sensor: mechanisms of detection of phagosome signals.
Q34602070The ability of Mycobacterium avium subsp. paratuberculosis to enter bovine epithelial cells is influenced by preexposure to a hyperosmolar environment and intracellular passage in bovine mammary epithelial cells
Q34759935The two murein lipoproteins of Salmonella enterica serovar Typhimurium contribute to the virulence of the organism
Q39282688The type VI secretion system gene cluster of Salmonella typhimurium: required for full virulence in mice
Q35073689Thioredoxin 1 promotes intracellular replication and virulence of Salmonella enterica serovar Typhimurium
Q38659206Toll-like receptor-deficient mice reveal how innate immune signaling influences Salmonella virulence strategies
Q39570899Trafficking of porin-deficient Salmonella typhimurium mutants inside HeLa cells: ompR and envZ mutants are defective for the formation of Salmonella-induced filaments.
Q34403839Transfer of eukaryotic expression plasmids to mammalian host cells by bacterial carriers
Q42214747Transfusion of stored blood impairs host defenses against Gram-negative pathogens in mice
Q37877525Transgene as vaccine for chlamydia
Q34949822Use of a dual reporter plasmid to demonstrate Bactofection with an attenuated AroA(-) derivative of Pasteurella multocida B:2
Q45190803speG Is Required for Intracellular Replication of Salmonella in Various Human Cells and Affects Its Polyamine Metabolism and Global Transcriptomes
Q37112109γδ T cells exhibit multifunctional and protective memory in intestinal tissues.

Search more.