DPP4 in Diabetes

scientific article (publication date: 2015)

DPP4 in Diabetes is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3389/FIMMU.2015.00386
P3181OpenCitations bibliographic resource ID1467326
P932PMC publication ID4515598
P698PubMed publication ID26284071
P5875ResearchGate publication ID281141658

P2093author name stringDiana Röhrborn
Juergen Eckel
Nina Wronkowitz
P2860cites workObesity, Metabolic Syndrome, and Cardiovascular DiseaseQ22241664
Internalization of CD26 by mannose 6-phosphate/insulin-like growth factor II receptor contributes to T cell activationQ22254628
One site mutation disrupts dimer formation in human DPP-IV proteinsQ24305361
Molecular cloning of fibroblast activation protein alpha, a member of the serine protease family selectively expressed in stromal fibroblasts of epithelial cancersQ24319154
The protease complex consisting of dipeptidyl peptidase IV and seprase plays a role in the migration and invasion of human endothelial cells in collagenous matricesQ24323082
Endothelial catabolism of extracellular adenosine during hypoxia: the role of surface adenosine deaminase and CD26Q24323818
Inosine binds to A3 adenosine receptors and stimulates mast cell degranulationQ24561372
The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanismQ27640960
A comparative study of the binding modes of recently launched dipeptidyl peptidase IV inhibitors in the active siteQ27684194
Omarigliptin (MK-3102): a novel long-acting DPP-4 inhibitor for once-weekly treatment of type 2 diabetesQ27689597
Dipeptidyl peptidase IV and related enzymes in cell biology and liver disordersQ28116286
Kinetic investigation of chemokine truncation by CD26/dipeptidyl peptidase IV reveals a striking selectivity within the chemokine familyQ28199376
Dipeptidyl peptidase-4 inhibitor attenuates hepatic fibrosis via suppression of activated hepatic stellate cell in ratsQ28286911
Glucose regulation of dipeptidyl peptidase IV gene expression is mediated by hepatocyte nuclear factor-1alpha in epithelial intestinal cellsQ28289423
Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitusQ28297680
Alogliptin after acute coronary syndrome in patients with type 2 diabetesQ28297690
Improvement of high fat-diet-induced insulin resistance in dipeptidyl peptidase IV-deficient Fischer ratsQ28574165
The cysteine-rich region of dipeptidyl peptidase IV (CD 26) is the collagen-binding siteQ28578376
Domain‐Specific N‐Glycosylation of the Membrane Glycoprotein Dipeptidylpeptidase IV (CD26) Influences its Subcellular Trafficking, Biological Stability, Enzyme Activity and Protein FoldingQ28582112
Linagliptin improves insulin sensitivity and hepatic steatosis in diet-induced obesityQ28728101
Liver fibrosisQ29547449
Mechanisms of hepatic fibrogenesisQ29619336
Adipose tissue as an endocrine organQ29620407
Circulating CD26 is negatively associated with inflammation in human and experimental arthritisQ31144845
Physical exercise reduces the expression of RANTES and its CCR5 receptor in the adipose tissue of obese humansQ33594449
Serum Dipeptidyl Peptidase-4 Activity in Insulin Resistant Patients with Non-Alcoholic Fatty Liver Disease: A Novel Liver Disease BiomarkerQ33678705
Dipeptidyl-peptidase IV (CD26)--role in the inactivation of regulatory peptidesQ33788748
Protease-resistant stromal cell-derived factor-1 for the treatment of experimental peripheral artery disease.Q33845786
CD26, adenosine deaminase, and adenosine receptors mediate costimulatory signals in the immunological synapse.Q33892260
Pancreatic beta cells synthesize neuropeptide Y and can rapidly release peptide co-transmittersQ33894840
Anagliptin in the treatment of type 2 diabetes: safety, efficacy, and patient acceptability.Q38401198
Incretin-based therapies for obesity treatmentQ38527160
DPP-IV inhibitor anagliptin exerts anti-inflammatory effects on macrophages, adipocytes, and mouse livers by suppressing NF-κB activationQ38870486
Substance P promotes diabetic corneal epithelial wound healing through molecular mechanisms mediated via the neurokinin-1 receptorQ38976880
Anagliptin, a DPP-4 inhibitor, suppresses proliferation of vascular smooth muscles and monocyte inflammatory reaction and attenuates atherosclerosis in male apo E-deficient miceQ39207307
Quantification of intact and truncated stromal cell-derived factor-1α in circulation by immunoaffinity enrichment and tandem mass spectrometryQ39255466
Dipeptidyl-peptidase-IV by cleaving neuropeptide Y induces lipid accumulation and PPAR-γ expression.Q39310752
Role of dipeptidyl peptidase IV (DPP4) in the development of dyslipidemia: DPP4 contributes to the steroid metabolism pathwayQ39636280
Sitagliptin as a novel treatment agent for non-alcoholic Fatty liver disease patients with type 2 diabetes mellitusQ39694021
Inhibition of monocyte adhesion to endothelial cells and attenuation of atherosclerotic lesion by a glucagon-like peptide-1 receptor agonist, exendin-4.Q39778606
Synergy between CD26/DPP-IV inhibition and G-CSF improves cardiac function after acute myocardial infarction.Q39990285
Distribution of GLP-1 and PACAP receptors in human tissuesQ41130734
Clinical audit of patients using DPP4 inhibitors in longstanding type 2 diabetesQ41731913
Cardioprotective and vasodilatory actions of glucagon-like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor-dependent and -independent pathwaysQ42165735
Dipeptidyl Peptidase IV Inhibitor Improves Insulin Resistance and Steatosis in a Refractory Nonalcoholic Fatty Liver Disease Patient: A Case ReportQ42322703
The role of adenosine in insulin action coupling in rat adipocytesQ42502703
The exenatide analogue AC3174 attenuates hypertension, insulin resistance, and renal dysfunction in Dahl salt-sensitive ratsQ42533774
Advanced glycation end products evoke endothelial cell damage by stimulating soluble dipeptidyl peptidase-4 production and its interaction with mannose 6-phosphate/insulin-like growth factor II receptor.Q42589786
Human dipeptidyl peptidase IV gene promoter: tissue-specific regulation from a TATA-less GC-rich sequence characteristic of a housekeeping gene promoterQ42822338
Insulinotropin PACAP potentiates insulin action. Stimulation of glucose uptake in 3T3-LI adipocytesQ42831876
Long-term dipeptidyl-peptidase 4 inhibition reduces atherosclerosis and inflammation via effects on monocyte recruitment and chemotaxisQ42987834
The myocardial infarct size-limiting effect of sitagliptin is PKA-dependent, whereas the protective effect of pioglitazone is partially dependent on PKA.Q43140566
Treatment with the dipeptidyl peptidase-4 inhibitor vildagliptin improves fasting islet-cell function in subjects with type 2 diabetesQ43194107
The DPP-4 inhibitor linagliptin restores β-cell function and survival in human isolated islets through GLP-1 stabilizationQ43804777
Soluble CD26/dipeptidyl peptidase IV enhances transendothelial migration via its interaction with mannose 6-phosphate/insulin-like growth factor II receptorQ44079524
Pharmacokinetics and metabolism of [14C]anagliptin, a novel dipeptidyl peptidase-4 inhibitor, in humansQ44230026
Cardioprotective effect of dipeptidyl peptidase-4 inhibitor during ischemia-reperfusion injuryQ44369782
Dual effects of pituitary adenylate cyclase-activating polypeptide and isoproterenol on lipid metabolism and signaling in primary rat adipocytesQ44576271
Dipeptidyl peptidase-IV expression and activity in human glomerular endothelial cells.Q44597640
Extreme reduction of dipeptidyl peptidase IV activity in F344 rat substrains is associated with various behavioral differencesQ44624787
Dipeptidyl(amino)peptidase IV and aminopeptidase M metabolize circulating substance P in vivoQ44727485
Effects of glucagon-like peptide-1 in patients with acute myocardial infarction and left ventricular dysfunction after successful reperfusionQ44774818
Insulin secretion and incretin hormones after oral glucose in non-obese subjects with impaired glucose toleranceQ44887107
Dipeptidyl aminopeptidase IV in hospitalized patients and in galactosamine hepatitis of the rat: Activity and lectin affinity chromatography in serum and hepatic plasma membranesQ44974021
Proline in transmembrane domain of type II protein DPP-IV governs its translocation behavior through endoplasmic reticulumQ45092446
Dipeptidyl peptidase 4-deficient rats have improved bile secretory function in high fat diet-induced steatosisQ45254506
Linagliptin alleviates hepatic steatosis and inflammation in a mouse model of non-alcoholic steatohepatitisQ45805661
Progressive attenuation of myocardial vascular endothelial growth factor expression is a seminal event in diabetic cardiomyopathy: restoration of microvascular homeostasis and recovery of cardiac function in diabetic cardiomyopathy after replenishmeQ45883055
Phenotyping of congenic dipeptidyl peptidase 4 (DP4) deficient Dark Agouti (DA) rats suggests involvement of DP4 in neuro-, endocrine, and immune functionsQ46071696
DPP-IV inhibition enhances the antilipolytic action of NPY in human adipose tissueQ46143099
Interrelationship of dipeptidyl peptidase IV (DPP4) with the development of diabetes, dyslipidaemia and nephropathy: a streptozotocin-induced model using wild-type and DPP4-deficient ratsQ46309791
The significance of hypersialylation of dipeptidyl peptidase IV (CD26) in the inhibition of its activity by Tat and other cationic peptides. CD26: a subverted adhesion molecule for HIV peptide bindingQ46314551
Comprehensive genetic analysis of the dipeptidyl peptidase-4 gene and cardiovascular disease risk factors in obese individualsQ46443903
Inhibition of CD26/dipeptidyl peptidase IV enhances CCL11/eotaxin-mediated recruitment of eosinophils in vivo.Q46497442
Characterization of the adenosine deaminase-adenosine deaminase complexing protein binding reactionQ46733796
Dipeptidyl-peptidase IV converts intact B-type natriuretic peptide into its des-SerPro formQ46778176
Association of systemic chemokine concentrations with impaired glucose tolerance and type 2 diabetes: results from the Cooperative Health Research in the Region of Augsburg Survey S4 (KORA S4).Q46818578
Effects of sitagliptin in diabetic patients with nonalcoholic steatohepatitisQ84746720
DPP-4 inhibitor des-F-sitagliptin treatment increased insulin exocytosis from db/db mice β cellsQ84795883
Sitagliptin prevents the development of metabolic and hormonal disturbances, increased β-cell apoptosis and liver steatosis induced by a fructose-rich diet in normal ratsQ84959531
Nonalcoholic fatty liver diseaseQ85213566
GLP-1 receptor activation indirectly reduces hepatic lipid accumulation but does not attenuate development of atherosclerosis in diabetic male ApoE(-/-) miceQ85538281
Role of glucose-dependent insulinotropic polypeptide in adipose tissue inflammation of dipeptidylpeptidase 4-deficient ratsQ86115184
Dipeptidyl peptidase-4 modulates left ventricular dysfunction in chronic heart failure via angiogenesis-dependent and -independent actionsQ87408607
Do dipeptidyl peptidase-4 inhibitors increase the risk of heart failure?Q88223737
Exendin-4 stimulates proliferation of human coronary artery endothelial cells through eNOS-, PKA- and PI3K/Akt-dependent pathways and requires GLP-1 receptorQ84187312
Combination therapies of DPP4 inhibitors and GLP1 analogues with insulin in type 2 diabetic patients: a systematic reviewQ84438092
DPP4 deficiency preserves cardiac function via GLP-1 signaling in rats subjected to myocardial ischemia/reperfusionQ84543059
Natriuretic peptides (BNP and NT-proBNP): measurement and relevance in heart failureQ33902623
The oral dipeptidyl peptidase-4 inhibitor sitagliptin increases circulating endothelial progenitor cells in patients with type 2 diabetes: possible role of stromal-derived factor-1alpha.Q33932817
Comparison of GLP-1 analogues versus sitagliptin in the management of type 2 diabetes: systematic review and meta-analysis of head-to-head studiesQ33999894
The association of hemoglobin a1c with incident heart failure among people without diabetes: the atherosclerosis risk in communities studyQ34024341
Pleiotropic effects of the dipeptidylpeptidase-4 inhibitors on the cardiovascular systemQ34062829
Tissue factor-protease-activated receptor 2 signaling promotes diet-induced obesity and adipose inflammation.Q34226558
DPP-4 inhibitors improve liver dysfunction in type 2 diabetes mellitusQ34237983
Diet-induced obesity, adipose inflammation, and metabolic dysfunction correlating with PAR2 expression are attenuated by PAR2 antagonismQ34365510
Risk of cardiovascular disease events in patients with type 2 diabetes prescribed the glucagon-like peptide 1 (GLP-1) receptor agonist exenatide twice daily or other glucose-lowering therapies: a retrospective analysis of the LifeLink databaseQ34422144
Trelagliptin: First Global ApprovalQ34482528
A Novel Consensus Motif in Fibronectin Mediates Dipeptidyl Peptidase IV Adhesion and MetastasisQ34533162
GLP-1 receptor agonists vs. DPP-4 inhibitors for type 2 diabetes: is one approach more successful or preferable than the other?Q34547492
Biological actions of the incretins GIP and GLP-1 and therapeutic perspectives in patients with type 2 diabetes.Q34560590
The possible protective role of glucagon-like peptide 1 on endothelium during the meal and evidence for an "endothelial resistance" to glucagon-like peptide 1 in diabetesQ34583386
Dipeptidyl peptidase IV inhibitor sitagliptin reduces local inflammation in adipose tissue and in pancreatic islets of obese miceQ34597496
Rigidity and flexibility of dipeptidyl peptidase IV: crystal structures of and docking experiments with DPIV.Q34651364
A new dipeptide naphthylamidase hydrolyzing glycyl-prolyl-beta-naphthylamideQ34661843
Evidence for a role of dipeptidyl peptidase IV in fibronectin-mediated interactions of hepatocytes with extracellular matrix.Q34668282
Effect of Sitagliptin on Cardiovascular Outcomes in Type 2 DiabetesQ34670462
Diet-induced adipose tissue inflammation and liver steatosis are prevented by DPP-4 inhibition in diabetic miceQ34718822
The dipeptidyl peptidase-4 inhibitor des-fluoro-sitagliptin regulates brown adipose tissue uncoupling protein levels in mice with diet-induced obesityQ34733928
Dipeptidyl peptidase 4 is a novel adipokine potentially linking obesity to the metabolic syndromeQ35063234
Changes in Adenosine Deaminase Activity in Patients with Type 2 Diabetes Mellitus and Effect of DPP-4 Inhibitor Treatment on ADA ActivityQ35067242
Beta cell function following 1 year vildagliptin or placebo treatment and after 12 week washout in drug-naive patients with type 2 diabetes and mild hyperglycaemia: a randomised controlled trialQ35091620
Seprase-dPPIV association and prolyl peptidase and gelatinase activities of the protease complexQ35098605
Mice lacking dipeptidyl peptidase IV are protected against obesity and insulin resistanceQ35144434
RANTES (CCL5) reduces glucose-dependent secretion of glucagon-like peptides 1 and 2 and impairs glucose-induced insulin secretion in miceQ35175990
Dipeptidyl-peptidase IV from bench to bedside: an update on structural properties, functions, and clinical aspects of the enzyme DPP IV.Q35189265
Comparison of treatment with sitagliptin or sulfonylurea in patients with type 2 diabetes mellitus and mild renal impairment: a post hoc analysis of clinical trialsQ35217932
Characterization of dedifferentiating human mature adipocytes from the visceral and subcutaneous fat compartments: fibroblast-activation protein alpha and dipeptidyl peptidase 4 as major components of matrix remodelingQ35224828
Enhancing Incretin Action for the Treatment of Type 2 DiabetesQ35545683
Role of substance P in the regulation of glucose metabolism via insulin signaling-associated pathwaysQ35590819
The role of metformin in the management of NAFLDQ35614956
Enhanced insulin secretion and improved glucose tolerance in mice lacking CD26.Q35809679
CCR5 plays a critical role in obesity-induced adipose tissue inflammation and insulin resistance by regulating both macrophage recruitment and M1/M2 statusQ36047622
Endothelial actions of atrial and B-type natriuretic peptidesQ36159149
Sitagliptin exerts an antinflammatory actionQ36201556
A marker for neoplastic progression of human melanocytes is a cell surface ectopeptidaseQ36361511
A potential role for dendritic cell/macrophage-expressing DPP4 in obesity-induced visceral inflammationQ36477217
Structure and function in dipeptidyl peptidase IV and related proteinsQ36478604
Inhibition of DPP-4: a new therapeutic approach for the treatment of type 2 diabetesQ36779756
Dipeptidyl peptidase-4: a key player in chronic liver diseaseQ36783164
Comparison of the dipeptidyl peptidase-4 gene methylation levels between severely obese subjects with and without the metabolic syndromeQ36799402
Stromal cell derived factor-1alpha protects stem cell derived insulin-producing cells from glucotoxicity under high glucose conditions in-vitro and ameliorates drug induced diabetes in ratsQ36863430
Inflamed adipose tissue: a culprit underlying the metabolic syndrome and atherosclerosisQ36933062
A critical analysis of the clinical use of incretin-based therapies: Are the GLP-1 therapies safe?Q36942123
Conditioning response to granulocyte colony-stimulating factor via the dipeptidyl peptidase IV-adenosine deaminase complex.Q37176935
Dipeptidyl peptidase-4 inhibitors in type 2 diabetes therapy--focus on alogliptin.Q37195882
Adipose dipeptidyl peptidase-4 and obesity: correlation with insulin resistance and depot-specific release from adipose tissue in vivo and in vitroQ37331331
On the origin of serum CD26 and its altered concentration in cancer patients.Q37532070
CD26 up-regulates expression of CD86 on antigen-presenting cells by means of caveolin-1.Q37557487
Therapeutic vaccine against DPP4 improves glucose metabolism in miceQ37687552
Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connectionQ37739949
Cardiovascular effects of DPP-4 inhibition: beyond GLP-1.Q37888004
Incretin-based therapiesQ37894864
Pharmacology of dipeptidyl peptidase-4 inhibitors: similarities and differences.Q37910902
A review of gliptins in 2011.Q37965612
A critical analysis of the clinical use of incretin-based therapies: The benefits by far outweigh the potential risksQ38104338
Effects of glucagon-like peptide 1 on appetite and body weight: focus on the CNS.Q38170080
Peptide YY: more than just an appetite regulatorQ38219346
Significance of CXCL12 in type 2 diabetes mellitus and its associated complicationsQ38236202
Pharmacology, physiology, and mechanisms of action of dipeptidyl peptidase-4 inhibitorsQ38248682
The effects of dipeptidyl peptidase-4 inhibition on microvascular diabetes complications.Q38253620
Incretin-based therapiesQ38279785
MK-0626, a selective DPP-4 inhibitor, attenuates hepatic steatosis in ob/ob miceQ38302500
Pituitary adenylate cyclase-activating peptide (PACAP): assessment of dipeptidyl peptidase IV degradation, insulin-releasing activity and antidiabetic potential.Q38316922
Teneligliptin : expectations for its pleiotropic actionQ38322300
Dipeptidyl peptidase IV (DPP4)-deficiency attenuates diet-induced obesity in rats: Possible implications for the hypothalamic neuropeptidergic systemQ38340409
Dipeptidyl peptidase-4 (DPP-4): Localization and activity in human and rodent isletsQ46832007
Dipeptidyl peptidase 4 (DPP-4) is expressed in mouse and human islets and its activity is decreased in human islets from individuals with type 2 diabetesQ46878138
Characterization of the influence of vildagliptin on model-assessed -cell function in patients with type 2 diabetes and mild hyperglycemiaQ46959131
DPP4-deficient congenic rats display blunted stress, improved fear extinction and increased central NPY.Q47752660
Increased circulating RANTES in type 2 diabetesQ47834737
Circulating dipeptidyl peptidase IV activity correlates with cardiac dysfunction in human and experimental heart failure.Q47914982
Des-serine-proline brain natriuretic peptide 3-32 in cardiorenal regulationQ48386405
Vildagliptin selectively ameliorates GLP-1, GLUT4, SREBP-1c mRNA levels and stimulates β-cell proliferation resulting in improved glucose homeostasis in rats with streptozotocin-induced diabetesQ49143530
Effects of sitagliptin on nonalcoholic fatty liver disease in diet-induced obese rats.Q51254742
Impact of treatment with saxagliptin on glycaemic stability and β-cell function in the SAVOR-TIMI 53 study.Q51308310
A dipeptidyl peptidase-4 inhibitor, des-fluoro-sitagliptin, improves endothelial function and reduces atherosclerotic lesion formation in apolipoprotein E-deficient mice.Q51362571
Effect of sitagliptin plus metformin on β-cell function, islet integrity and islet gene expression in Zucker diabetic fatty rats.Q51378610
Substance P is associated with the development of obesity, chronic inflammation and type 2 diabetes mellitus.Q51394418
Chronic inhibition of dipeptidyl peptidase-4 with a sitagliptin analog preserves pancreatic beta-cell mass and function in a rodent model of type 2 diabetes.Q51497444
Polymorphisms in dipeptidyl peptidase IV gene are associated with the risk of myocardial infarction in patients with atherosclerosis.Q51535856
Reduced postprandial concentrations of intact biologically active glucagon-like peptide 1 in type 2 diabetic patients.Q51550359
Shedding of dipeptidyl peptidase 4 is mediated by metalloproteases and up-regulated by hypoxia in human adipocytes and smooth muscle cells.Q51697808
Dipeptidyl peptidase IV (DDP IV) in NASH patients.Q51727865
Deficiency of CD26 results in a change of cytokine and immunoglobulin secretion after stimulation by pokeweed mitogen.Q52951285
Reduction of both beta cell death and alpha cell proliferation by dipeptidyl peptidase-4 inhibition in a streptozotocin-induced model of diabetes in mice.Q53207032
Soluble DPP4 induces inflammation and proliferation of human smooth muscle cells via protease-activated receptor 2.Q54203121
Protective effects of sitagliptin on myocardial injury and cardiac function in an ischemia/reperfusion rat model.Q54408588
The novel dipeptidyl peptidase-4 inhibitor teneligliptin prevents high-fat diet-induced obesity accompanied with increased energy expenditure in mice.Q54485185
DPP4 Gene DNA Methylation in the Omentum is Associated With Its Gene Expression and Plasma Lipid Profile in Severe ObesityQ57316296
Regulation of CD26/DPPIV gene expression by interferons and retinoic acid in tumor B cellsQ57662605
Variation at the DPP4 locus influences apolipoprotein B levels in South Asians and exhibits heterogeneity in Europeans related to BMIQ58039484
Soluble CD26 / Dipeptidyl Peptidase IV Enhances Human Lymphocyte Proliferation In Vitro Independent of Dipeptidyl Peptidase Enzyme Activity and Adenosine Deaminase BindingQ60617843
Two highly conserved glutamic acid residues in the predicted β propeller domain of dipeptidyl peptidase IV are required for its enzyme activityQ60617869
MECHANISMS OF CD26/DIPEPTIDYL PEPTIDASE IV CYTOKINE-DEPENDENT REGULATION ON HUMAN ACTIVATED LYMPHOCYTESQ62399778
Tissue distribution of messenger ribonucleic acid encoding the rat glucagon-like peptide-1 receptor.Q64998688
Altered zonal expression of the CD26 antigen (dipeptidyl peptidase IV) in human cirrhotic liverQ67516828
Changes of dipeptidylpeptidase IV as a membrane marker of lymphocytes in acute and chronic liver diseases--biochemical and cytochemical investigationsQ68321083
Organ distribution of aminopeptidase A and dipeptidyl peptidase IV in normal miceQ71071202
Adenosine effects upon insulin action on lipolysis and glucose transport in human adipocytesQ71926800
Antibody-induced modulation of CD26 surface expressionQ72333319
Dipeptidyl peptidase IV (CD 26) and aminopeptidase N (CD 13) catalyzed hydrolysis of cytokines and peptides with N-terminal cytokine sequencesQ72660582
Interleukin-12 enhances CD26 expression and dipeptidyl peptidase IV function on human activated lymphocytesQ73980584
Decreased cardiac expression of vascular endothelial growth factor and its receptors in insulin-resistant and diabetic States: a possible explanation for impaired collateral formation in cardiac tissueQ77531118
Glucagon-like peptide-1 infusion improves left ventricular ejection fraction and functional status in patients with chronic heart failureQ79437872
Overexpression of brain natriuretic peptide facilitates neutrophil infiltration and cardiac matrix metalloproteinase-9 expression after acute myocardial infarctionQ81011391
Inhibition of dipeptidyl peptidase-4 augments insulin secretion in response to exogenously administered glucagon-like peptide-1, glucose-dependent insulinotropic polypeptide, pituitary adenylate cyclase-activating polypeptide, and gastrin-releasingQ81157658
Stromal cell derived factor-1 (SDF-1)/CXCL12 attenuates diabetes in mice and promotes pancreatic beta-cell survival by activation of the prosurvival kinase AktQ81317103
Hepatic fibrogenesisQ81544375
The DPP-4 inhibitor vildagliptin increases pancreatic beta cell mass in neonatal ratsQ82427245
Increased hepatic expression of dipeptidyl peptidase-4 in non-alcoholic fatty liver disease and its association with insulin resistance and glucose metabolismQ83011265
Exendin-4, a glucagon-like peptide-1 receptor agonist, reduces intimal thickening after vascular injuryQ83151449
Association between HbA1c and dipeptidyl peptidase IV activity in type 2 diabetes mellitusQ83618199
Serum levels of calcitonin gene-related peptide and substance P are decreased in patients with diabetes mellitus and coronary artery diseaseQ83689985
Association of stromal cell-derived factor 1 genotype with diabetic foot syndrome and macrovascular disease in patients with type 2 diabetesQ83840257
Crystal structures of DPP-IV (CD26) from rat kidney exhibit flexible accommodation of peptidase-selective inhibitorsQ83973657
P407language of work or nameEnglishQ1860
P304page(s)386
P577publication date2015-01-01
P1433published inFrontiers in ImmunologyQ27723748
P1476titleDPP4 in Diabetes
P478volume6

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Q64226372Polyalthia Clerodane Diterpene Potentiates Hypoglycemia via Inhibition of Dipeptidyl Peptidase 4
Q51733912Reduction of soluble dipeptidyl peptidase 4 levels in plasma of patients infected with Middle East respiratory syndrome coronavirus.
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