Kinetic investigation of chemokine truncation by CD26/dipeptidyl peptidase IV reveals a striking selectivity within the chemokine family

scientific article (publication date: 10 August 2001)

Kinetic investigation of chemokine truncation by CD26/dipeptidyl peptidase IV reveals a striking selectivity within the chemokine family is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M103106200
P8608Fatcat IDrelease_mx4dzloykjdghejpt7dmhshhe4
P3181OpenCitations bibliographic resource ID232303
P698PubMed publication ID11390394

P50authorIngrid De MeesterQ62670225
Anne-Marie LambeirQ41790695
Paul ProostQ54449101
Christine DurinxQ59491456
P2093author name stringVan Damme J
Scharpé S
Bal G
Augustyns K
Senten K
P2860cites workIsolation of the CXC chemokines ENA-78, GRO alpha and GRO gamma from tumor cells and leukocytes reveals NH2-terminal heterogeneity. Functional comparison of different natural isoformsQ22009107
Human IP-9: A keratinocyte-derived high affinity CXC-chemokine ligand for the IP-10/Mig receptor (CXCR3)Q22009509
Inhibition of HIV-1 infection by the beta-chemokine MDCQ24309584
Identification of amino acid residues critical for aggregation of human CC chemokines macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, and RANTES. Characterization of active disaggregated chemokine variantsQ27618367
Structures of prolyl oligopeptidase substrate/inhibitor complexes. Use of inhibitor binding for titration of the catalytic histidine residueQ27627477
Proton NMR assignments and solution conformation of RANTES, a chemokine of the C-C typeQ27729420
Solution structure of eotaxin, a chemokine that selectively recruits eosinophils in allergic inflammationQ27765156
On the size of the active site in proteases. I. PapainQ27860826
LD78beta, a non-allelic variant of human MIP-1alpha (LD78alpha), has enhanced receptor interactions and potent HIV suppressive activityQ28199341
Dendritic cells as a major source of macrophage-derived chemokine/CCL22 in vitro and in vivoQ28203975
Delayed production of biologically active O-glycosylated forms of human eotaxin by tumor-necrosis-factor-alpha-stimulated dermal fibroblastsQ28270212
Truncation of macrophage-derived chemokine by CD26/ dipeptidyl-peptidase IV beyond its predicted cleavage site affects chemotactic activity and CC chemokine receptor 4 interactionQ28296438
Chemokines: a new classification system and their role in immunityQ29615663
Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and diseaseQ29616432
Chemokines and leukocyte trafficQ29618886
Metabolism of glucagon by dipeptidyl peptidase IV (CD26).Q30976346
Functional comparison of two human monocyte chemotactic protein-2 isoforms, role of the amino-terminal pyroglutamic acid and processing by CD26/dipeptidyl peptidase IV.Q32025761
Rapid inactivation of stromal cell-derived factor-1 by cathepsin G associated with lymphocytesQ32159654
CD26, let it cut or cut it down.Q33702158
Dipeptidyl-peptidase IV (CD26)--role in the inactivation of regulatory peptidesQ33788748
Co-receptor use by HIV and inhibition of HIV infection by chemokine receptor ligandsQ34118741
The role of chemokines in human immunodeficiency virus infectionQ34118829
Chemokines, cytokines and HIV: a complex network of interactions that influence HIV pathogenesisQ34118839
Lymphocyte traffic control by chemokinesQ34139610
Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1.Q34447967
Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophagesQ36340560
Regulation of the receptor specificity and function of the chemokine RANTES (regulated on activation, normal T cell expressed and secreted) by dipeptidyl peptidase IV (CD26)-mediated cleavageQ36380925
The LD78beta isoform of MIP-1alpha is the most potent CCR5 agonist and HIV-1-inhibiting chemokineQ36736256
Anti-HIV-1 and chemotactic activities of human stromal cell-derived factor 1alpha (SDF-1alpha) and SDF-1beta are abolished by CD26/dipeptidyl peptidase IV-mediated cleavage.Q37400834
Molecular analysis of CD26-mediated signal transduction in T cellsQ39091438
Negative regulation of the anti-human immunodeficiency virus and chemotactic activity of human stromal cell-derived factor 1alpha by CD26/dipeptidyl peptidase IV.Q39318764
Amino-terminal truncation of chemokines by CD26/dipeptidyl-peptidase IV. Conversion of RANTES into a potent inhibitor of monocyte chemotaxis and HIV-1-infection.Q39369861
Processing by CD26/dipeptidyl-peptidase IV reduces the chemotactic and anti-HIV-1 activity of stromal-cell-derived factor-1alphaQ39369867
CD26-processed RANTES(3-68), but not intact RANTES, has potent anti-HIV-1 activity.Q39438516
Natural truncation of RANTES abolishes signaling through the CC chemokine receptors CCR1 and CCR3, impairs its chemotactic potency and generates a CC chemokine inhibitor.Q39494558
Proline-dependent structural and biological properties of peptides and proteinsQ40881554
The N-terminal structure of HIV-1 Tat is required for suppression of CD26-dependent T cell growthQ44112317
A prediction of DPP IV/CD26 domain structure from a physico-chemical investigation of dipeptidyl peptidase IV (CD26) from human seminal plasmaQ57975973
P433issue32
P407language of work or nameEnglishQ1860
P1104number of pages7
P304page(s)29839-29845
P577publication date2001-06-04
P1433published inJournal of Biological ChemistryQ867727
P1476titleKinetic investigation of chemokine truncation by CD26/dipeptidyl peptidase IV reveals a striking selectivity within the chemokine family
P478volume276

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