| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Valentina Manzo | Q58424077 |
| Filippelli A | Q61153398 | ||
| Valeria Conti | Q63962298 | ||
| Graziamaria Corbi | Q46857851 | ||
| Alessandro Vatrella | Q48541083 | ||
| P2093 | author name string | G Pelaia | |
| P2860 | cites work | Release and Activity of Matrix Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-1 by Alveolar Macrophages from Patients with Chronic Obstructive Pulmonary Disease | Q61496390 |
| Pulmonary function, oxidative stress and inflammatory markers in severe COPD exacerbation | Q82120465 | ||
| Different patterns of lung sirtuin expression in smokers with and without chronic obstructive pulmonary disease | Q85905320 | ||
| Aging-related changes in oxidative stress response of human endothelial cells | Q87041767 | ||
| Monitoring oxidative stress during chronic obstructive pulmonary disease exacerbations using malondialdehyde | Q87058474 | ||
| Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease | Q22299313 | ||
| Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase | Q24293656 | ||
| mTOR signaling in growth control and disease | Q24634174 | ||
| Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway | Q24643816 | ||
| Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes | Q24645537 | ||
| Rapamycin fed late in life extends lifespan in genetically heterogeneous mice | Q24647805 | ||
| Regulation of Akt signaling by sirtuins: its implication in cardiac hypertrophy and aging | Q26998765 | ||
| Is physical activity able to modify oxidative damage in cardiovascular aging? | Q27025850 | ||
| MARK-AGE biomarkers of ageing | Q28082933 | ||
| Inflamm-aging. An evolutionary perspective on immunosenescence | Q28141817 | ||
| Duration of nuclear NF-kappaB action regulated by reversible acetylation | Q28215080 | ||
| Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants | Q28218883 | ||
| Histone acetylation and deacetylation: importance in inflammatory lung diseases | Q28237379 | ||
| Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases | Q28239642 | ||
| Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients | Q28282424 | ||
| Protein composition of catalytically active human telomerase from immortal cells | Q28295708 | ||
| Glucocorticoid insensitivity as a future target of therapy for chronic obstructive pulmonary disease | Q28761895 | ||
| Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary | Q29614970 | ||
| International variation in the prevalence of COPD (the BOLD Study): a population-based prevalence study | Q29614971 | ||
| Genetics: influence of TOR kinase on lifespan in C. elegans | Q29616619 | ||
| Understanding the odd science of aging | Q29617341 | ||
| Progressive loss of SIRT1 with cell cycle withdrawal | Q30441451 | ||
| MMP9 modulates tight junction integrity and cell viability in human airway epithelia | Q30487603 | ||
| Serum metalloproteinase-9 is related to COPD severity and symptoms - cross-sectional data from a population based cohort-study | Q30925905 | ||
| Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease | Q33373335 | ||
| Heightened endoplasmic reticulum stress in the lungs of patients with chronic obstructive pulmonary disease: the role of Nrf2-regulated proteasomal activity | Q33551463 | ||
| Cytokine inhibition in the treatment of COPD. | Q33568552 | ||
| SIRT1 protects against cigarette smoke-induced lung oxidative stress via a FOXO3-dependent mechanism | Q33568637 | ||
| Application of proteomics and peptidomics to COPD. | Q33634488 | ||
| Age-related changes in tissue macrophages precede cardiac functional impairment | Q33801206 | ||
| Age related changes in NAD+ metabolism oxidative stress and Sirt1 activity in wistar rats | Q33889428 | ||
| Feasibility of 8-OHdG formation and hOGG1 induction in PBMCs for assessing oxidative DNA damage in the lung of COPD patients. | Q51050620 | ||
| Benefits of high-dose N-acetylcysteine to exacerbation-prone patients with COPD. | Q51734911 | ||
| Disturbed flow promotes endothelial senescence via a p53-dependent pathway. | Q53061350 | ||
| Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta-induced histone H4 acetylation on lysines 8 and 12. | Q33915125 | ||
| Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid | Q34301299 | ||
| Suppressed expression of T-box transcription factors is involved in senescence in chronic obstructive pulmonary disease | Q34350843 | ||
| Accelerated senescence of cord blood endothelial progenitor cells in premature neonates is driven by SIRT1 decreased expression | Q34403678 | ||
| COPD: maximization of bronchodilation | Q34436393 | ||
| SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner | Q34458982 | ||
| Implementing clinical guidelines for chronic obstructive pulmonary disease: barriers and solutions | Q34628637 | ||
| Inhaled corticosteroids in patients with stable chronic obstructive pulmonary disease: a systematic review and meta-analysis | Q34888769 | ||
| Inflammatory response in the elderly | Q35032400 | ||
| Free-radical chemistry of cigarette smoke and its toxicological implications | Q35035584 | ||
| Telomerase mutations in smokers with severe emphysema. | Q35056698 | ||
| FOXO3 deficiency leads to increased susceptibility to cigarette smoke-induced inflammation, airspace enlargement, and chronic obstructive pulmonary disease | Q35091274 | ||
| SnapShot: Mammalian Sirtuins. | Q35111981 | ||
| Denitrosylation of HDAC2 by targeting Nrf2 restores glucocorticosteroid sensitivity in macrophages from COPD patients | Q35484702 | ||
| Telomere length is a determinant of emphysema susceptibility. | Q35528495 | ||
| Oxidative stress and airway inflammation in severe exacerbations of COPD. | Q35537579 | ||
| AMPK is required for PM2.5-induced autophagy in human lung epithelial A549 cells | Q35580211 | ||
| Targeted deletion of Jun/AP-1 in alveolar epithelial cells causes progressive emphysema and worsens cigarette smoke-induced lung inflammation | Q35951960 | ||
| SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice | Q36005375 | ||
| Oxidative stress-induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease | Q36024291 | ||
| Geroprotectors as a novel therapeutic strategy for COPD, an accelerating aging disease | Q36283905 | ||
| Anti-inflammatory properties of sirtuin 6 in human umbilical vein endothelial cells | Q36364263 | ||
| Oxidative stress and redox regulation of lung inflammation in COPD. | Q36525624 | ||
| SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease. | Q36539471 | ||
| Recent results: biomarkers of aging | Q36637237 | ||
| Decline in NRF2-regulated antioxidants in chronic obstructive pulmonary disease lungs due to loss of its positive regulator, DJ-1 | Q36889964 | ||
| Potential mechanisms linking atherosclerosis and increased cardiovascular risk in COPD: focus on Sirtuins. | Q37007407 | ||
| Biological targets for therapeutic interventions in COPD: clinical potential | Q37018843 | ||
| Aging and induced senescence as factors in the pathogenesis of lung emphysema | Q37212594 | ||
| Adrenergic signaling and oxidative stress: a role for sirtuins? | Q37289500 | ||
| COPD as a disease of accelerated lung aging | Q37366212 | ||
| Nrf2 protects against airway disorders | Q37568208 | ||
| The aging immune system and its relationship to the development of chronic obstructive pulmonary disease | Q37637719 | ||
| Current concepts on oxidative/carbonyl stress, inflammation and epigenetics in pathogenesis of chronic obstructive pulmonary disease | Q37836078 | ||
| Franklin H. Epstein Lecture: Sirtuins, aging, and medicine | Q37886170 | ||
| mTOR signaling in disease | Q37941273 | ||
| Antioxidant pharmacological therapies for COPD. | Q37986343 | ||
| Current overview of functions of FoxO proteins, with special regards to cellular homeostasis, cell response to stress, as well as inflammation and aging. | Q38062814 | ||
| Can we delay the accelerated lung aging in COPD? Anti-aging molecules and interventions | Q38068942 | ||
| Crosstalk between Oxidative Stress and SIRT1: Impact on the Aging Process | Q38084036 | ||
| Histone deacetylases and their inhibitors: new implications for asthma and chronic respiratory conditions | Q38169885 | ||
| Cellular and molecular mechanisms of chronic obstructive pulmonary disease | Q38186290 | ||
| Signaling pathway cross talk in Alzheimer's disease | Q38200151 | ||
| Inhibitory effects of theophylline on the peroxynitrite-augmented release of matrix metalloproteinases by lung fibroblasts. | Q39404591 | ||
| A protein deacetylase SIRT1 is a negative regulator of metalloproteinase-9. | Q39859312 | ||
| Urban PM2.5 induces ROS generation and RBC damage in COPD patients. | Q39984991 | ||
| UV-mediated regulation of the anti-senescence factor Tbx2. | Q40048508 | ||
| Effect of spirulina intervention on oxidative stress, antioxidant status, and lipid profile in chronic obstructive pulmonary disease patients. | Q42174455 | ||
| Basal and glucocorticoid induced changes of hepatic glucocorticoid receptor during aging: relation to activities of tyrosine aminotransferase and tryptophan oxygenase. | Q42481521 | ||
| Oxidant/antioxidant imbalance in smokers and chronic obstructive pulmonary disease | Q42731155 | ||
| Oxidative stress induces endothelial cell senescence via downregulation of Sirt6. | Q42819649 | ||
| Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway | Q42878089 | ||
| Oxidative stress and antioxidant enzyme activity in South Indian male smokers with chronic obstructive pulmonary disease | Q43631213 | ||
| 4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease | Q44108450 | ||
| Autophagy induction by SIRT6 through attenuation of insulin-like growth factor signaling is involved in the regulation of human bronchial epithelial cell senescence. | Q44589393 | ||
| Peroxynitrite elevation in exhaled breath condensate of COPD and its inhibition by fudosteine | Q46135863 | ||
| Exercise training promotes SIRT1 activity in aged rats. | Q46857793 | ||
| The ARGA study with general practitioners: impact of medical education on asthma/rhinitis management | Q47996168 | ||
| P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | chronic obstructive pulmonary disease | Q199804 |
| enzyme | Q8047 | ||
| physiological phenomenon | Q66615932 | ||
| biomedical investigative technique | Q66648976 | ||
| P304 | page(s) | 897327 | |
| P577 | publication date | 2015-01-01 | |
| 2015-07-05 | |||
| P1433 | published in | Cellular Oncology | Q2160503 |
| P1476 | title | Sirtuin 1 and aging theory for chronic obstructive pulmonary disease | |
| P478 | volume | 2015 |
| Q89433943 | A highly significant association between Cathepsin S gene polymorphisms rs12068264 and chronic obstructive pulmonary disease susceptibility in Han Chinese population |
| Q54964741 | Analysis of Short-Term Smoking Effects in PBMC of Healthy Subjects-Preliminary Study. |
| Q93053027 | Cardioprotective Effects of Dietary Phytochemicals on Oxidative Stress in Heart Failure by a Sex-Gender-Oriented Point of View |
| Q64245878 | Chronic Obstructive Pulmonary Disease as a Main Factor of Premature Aging |
| Q41989026 | FOXO3a Gene Polymorphism Associated with Asthma in Indian Population |
| Q90062620 | Inflammaging and Oxidative Stress in Human Diseases: From Molecular Mechanisms to Novel Treatments |
| Q93113555 | Mitochondrial biology in airway pathogenesis and the role of NRF2 |
| Q38435673 | Molecular pathology endpoints useful for aging studies. |
| Q55268558 | Reactive Oxygen Species in Chronic Obstructive Pulmonary Disease. |
| Q54970037 | SIRT1 Activity in Peripheral Blood Mononuclear Cells Correlates with Altered Lung Function in Patients with Chronic Obstructive Pulmonary Disease. |
| Q55227397 | The Function of Ophiocordyceps sinensis in Airway Epithelial Cell Senescence in a Rat COPD Model. |
| Q37571664 | The Role of Mitochondria and Oxidative/Antioxidative Imbalance in Pathobiology of Chronic Obstructive Pulmonary Disease |
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