review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1016/J.MOLCEL.2015.06.010 |
P8608 | Fatcat ID | release_kbovlr4urvhrthj7oxwf5lsy6a |
P698 | PubMed publication ID | 26253026 |
P50 | author | Kazuhiro Nagata | Q11550232 |
Daisuke Morito | Q59683777 | ||
P2860 | cites work | BAP31 and BiP are essential for dislocation of SV40 from the endoplasmic reticulum to the cytosol | Q84985437 |
Multilayered mechanism of CD4 downregulation by HIV-1 Vpu involving distinct ER retention and ERAD targeting steps | Q21131559 | ||
Retrograde transport pathways utilised by viruses and protein toxins | Q21245139 | ||
A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation | Q24297209 | ||
A membrane protein required for dislocation of misfolded proteins from the ER | Q24297703 | ||
A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol | Q24297732 | ||
Defining human ERAD networks through an integrative mapping strategy | Q24298439 | ||
Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum | Q24298901 | ||
EDEM2 initiates mammalian glycoprotein ERAD by catalyzing the first mannose trimming step | Q24301651 | ||
Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation | Q24302539 | ||
The TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ER | Q24311488 | ||
Deubiquitinases sharpen substrate discrimination during membrane protein degradation from the ER | Q24311975 | ||
OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD | Q24312778 | ||
Protein disulphide isomerase is required for signal peptide peptidase-mediated protein degradation | Q24322026 | ||
Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction | Q24324602 | ||
Recruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membrane | Q24336904 | ||
HRD1 and UBE2J1 target misfolded MHC class I heavy chains for endoplasmic reticulum-associated degradation | Q24337606 | ||
Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane | Q24530318 | ||
A glycosylated type I membrane protein becomes cytosolic when peptide: N-glycanase is compromised | Q24535941 | ||
The human protein disulphide isomerase family: substrate interactions and functional properties | Q24537186 | ||
EDEM is involved in retrotranslocation of ricin from the endoplasmic reticulum to the cytosol | Q24541550 | ||
Folding-competent and folding-defective forms of ricin A chain have different fates after retrotranslocation from the endoplasmic reticulum | Q24600792 | ||
Two translocating hydrophilic segments of a nascent chain span the ER membrane during multispanning protein topogenesis | Q24645170 | ||
One step at a time: endoplasmic reticulum-associated degradation | Q24658302 | ||
Murine polyomavirus requires the endoplasmic reticulum protein Derlin-2 to initiate infection | Q24674111 | ||
Ubiquitination of serine, threonine, or lysine residues on the cytoplasmic tail can induce ERAD of MHC-I by viral E3 ligase mK3 | Q24683139 | ||
Ubiquitylation of an ERAD substrate occurs on multiple types of amino acids | Q26781978 | ||
Protein folding and quality control in the ER | Q26823157 | ||
Structural basis of an ERAD pathway mediated by the ER-resident protein disulfide reductase ERdj5 | Q27666741 | ||
The ubiquitin system | Q27860803 | ||
Key steps in ERAD of luminal ER proteins reconstituted with purified components | Q27929992 | ||
A luminal surveillance complex that selects misfolded glycoproteins for ER-associated degradation | Q27930372 | ||
Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins | Q27931299 | ||
The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol | Q27936514 | ||
Der1 promotes movement of misfolded proteins through the endoplasmic reticulum membrane | Q27938831 | ||
Retrotranslocation of a misfolded luminal ER protein by the ubiquitin-ligase Hrd1p | Q27938951 | ||
AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation | Q27939982 | ||
Molecular chaperones in the cytosol: from nascent chain to folded protein | Q28205903 | ||
EDEM as an acceptor of terminally misfolded glycoproteins released from calnexin | Q28212764 | ||
Cleaning up in the endoplasmic reticulum: ubiquitin in charge | Q28237362 | ||
Signal peptide peptidase is required for dislocation from the endoplasmic reticulum | Q28243253 | ||
A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif | Q28276184 | ||
How viruses and toxins disassemble to enter host cells | Q37891079 | ||
Cholera toxin: an intracellular journey into the cytosol by way of the endoplasmic reticulum | Q37954281 | ||
Quality control: ER-associated degradation: protein quality control and beyond | Q38196654 | ||
A cytosolic chaperone complexes with dynamic membrane J-proteins and mobilizes a nonenveloped virus out of the endoplasmic reticulum. | Q38542913 | ||
Role of the RING-CH domain of viral ligase mK3 in ubiquitination of non-lysine and lysine MHC I residues | Q39837294 | ||
The role of BiP in endoplasmic reticulum-associated degradation of major histocompatibility complex class I heavy chain induced by cytomegalovirus proteins. | Q40274580 | ||
The viral E3 ubiquitin ligase mK3 uses the Derlin/p97 endoplasmic reticulum-associated degradation pathway to mediate down-regulation of major histocompatibility complex class I proteins | Q40323216 | ||
Role of p97 AAA-ATPase in the retrotranslocation of the cholera toxin A1 chain, a non-ubiquitinated substrate | Q40414043 | ||
Virus subversion of the MHC class I peptide-loading complex | Q40677035 | ||
MHC class I ubiquitination by a viral PHD/LAP finger protein. | Q40773241 | ||
Simian Virus 40 depends on ER protein folding and quality control factors for entry into host cells | Q41623826 | ||
Real-time fluorescence detection of ERAD substrate retrotranslocation in a mammalian in vitro system. | Q41785201 | ||
Cholera toxin is exported from microsomes by the Sec61p complex | Q41861735 | ||
Transcriptome profile of murine gammaherpesvirus-68 lytic infection | Q44281971 | ||
Vpu-mediated degradation of CD4 reconstituted in yeast reveals mechanistic differences to cellular ER-associated protein degradation | Q44852706 | ||
p97 Is in a Complex with Cholera Toxin and Influences the Transport of Cholera Toxin and Related Toxins to the Cytoplasm | Q57372274 | ||
The peroxisomal importomer constitutes a large and highly dynamic pore | Q57856741 | ||
Ricin A chain utilises the endoplasmic reticulum-associated protein degradation pathway to enter the cytosol of yeast | Q73047414 | ||
Navigating the ERAD interaction network | Q83114417 | ||
ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER | Q28512215 | ||
The unfolded protein response: from stress pathway to homeostatic regulation | Q29547396 | ||
Roles of N-linked glycans in the endoplasmic reticulum | Q29616458 | ||
Intracellular functions of N-linked glycans | Q29617165 | ||
The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol | Q29618773 | ||
Virus entry: open sesame | Q29619349 | ||
TMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I. | Q29871423 | ||
An interaction between ricin and calreticulin that may have implications for toxin trafficking | Q31672834 | ||
The E3 ubiquitin ligases Hrd1 and gp78 bind to and promote cholera toxin retro-translocation | Q33571592 | ||
Cleavage by signal peptide peptidase is required for the degradation of selected tail-anchored proteins | Q33797023 | ||
A role for N-glycanase in the cytosolic turnover of glycoproteins | Q34179944 | ||
Hsp90 is required for transfer of the cholera toxin A1 subunit from the endoplasmic reticulum to the cytosol | Q34181280 | ||
The p97 ATPase dislocates MHC class I heavy chain in US2-expressing cells via a Ufd1-Npl4-independent mechanism | Q34186527 | ||
Ricin trafficking in cells | Q34457972 | ||
Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes | Q34719604 | ||
Establishment of an in vitro transport assay that reveals mechanistic differences in cytosolic events controlling cholera toxin and T-cell receptor α retro-translocation | Q35022480 | ||
Dislocation of ricin toxin A chains in human cells utilizes selective cellular factors | Q35065140 | ||
Cytolethal distending toxins require components of the ER-associated degradation pathway for host cell entry | Q35215974 | ||
Derlin-1 is a rhomboid pseudoprotease required for the dislocation of mutant α-1 antitrypsin from the endoplasmic reticulum | Q35381401 | ||
Transmembrane domain determinants of CD4 Downregulation by HIV-1 Vpu. | Q35665886 | ||
SEL1L, the homologue of yeast Hrd3p, is involved in protein dislocation from the mammalian ER. | Q36119119 | ||
TorsinA participates in endoplasmic reticulum-associated degradation | Q36487761 | ||
Derlin-1 facilitates the retro-translocation of cholera toxin | Q36488986 | ||
Antigen presentation and the ubiquitin-proteasome system in host-pathogen interactions | Q36673300 | ||
The ERdj5-Sel1L complex facilitates cholera toxin retrotranslocation | Q36680557 | ||
Mechanisms of CD4 downregulation by the Nef and Vpu proteins of primate immunodeficiency viruses | Q36754608 | ||
A stalled retrotranslocation complex reveals physical linkage between substrate recognition and proteasomal degradation during ER-associated degradation | Q36887431 | ||
Immunobiology of human cytomegalovirus: from bench to bedside. | Q37050965 | ||
Early events during BK virus entry and disassembly | Q37051570 | ||
MHC class I molecules are preferentially ubiquitinated on endoplasmic reticulum luminal residues during HRD1 ubiquitin E3 ligase-mediated dislocation. | Q37143424 | ||
Regulation of MHC class I assembly and peptide binding | Q37253085 | ||
HIV accessory proteins versus host restriction factors | Q37375080 | ||
CD4 and BST-2/tetherin proteins retro-translocate from endoplasmic reticulum to cytosol as partially folded and multimeric molecules | Q37428581 | ||
Life and death of a BiP substrate | Q37660656 | ||
ERAD substrates: which way out? | Q37660718 | ||
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 335-344 | |
P577 | publication date | 2015-08-06 | |
P1433 | published in | Molecular Cell | Q3319468 |
P1476 | title | Pathogenic Hijacking of ER-Associated Degradation: Is ERAD Flexible? | |
P478 | volume | 59 |
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Q91894003 | Contribution of the Unfolded Protein Response (UPR) to the Pathogenesis of Proteasome-Associated Autoinflammatory Syndromes (PRAAS) |
Q40080379 | Emerging roles of rhomboid-like pseudoproteases in inflammatory and innate immune responses |
Q30234505 | Endoplasmic Reticulum Stress, Unfolded Protein Response, and Cancer Cell Fate |
Q41922848 | Enterovirus 71 protease 2Apro and 3Cpro differentially inhibit the cellular endoplasmic reticulum-associated degradation (ERAD) pathway via distinct mechanisms, and enterovirus 71 hijacks ERAD component p97 to promote its replication. |
Q92255602 | Herpesviruses and the Unfolded Protein Response |
Q92055431 | Identification of proteins regulated by the proteasome following induction of endoplasmic reticulum stress |
Q90418737 | Mammalian membrane trafficking as seen through the lens of bacterial toxins |
Q31031297 | Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding. |
Q37727169 | Mouse Mammary Tumor Virus Signal Peptide Uses a Novel p97-Dependent and Derlin-Independent Retrotranslocation Mechanism To Escape Proteasomal Degradation |
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Q96306487 | Oncoprotein SND1 hijacks nascent MHC-I heavy chain to ER-associated degradation, leading to impaired CD8+ T cell response in tumor |
Q40603885 | Posttranscriptional Regulation of Glycoprotein Quality Control in the Endoplasmic Reticulum Is Controlled by the E2 Ub-Conjugating Enzyme UBC6e. |
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