The roles of mesenchymal stem cells in tumor inflammatory microenvironment

scientific article

The roles of mesenchymal stem cells in tumor inflammatory microenvironment is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P6179Dimensions Publication ID1004051038
P356DOI10.1186/1756-8722-7-14
P3181OpenCitations bibliographic resource ID1553596
P932PMC publication ID3943443
P698PubMed publication ID24502410
P5875ResearchGate publication ID260118913

P50authorRobert Chunhua ZhaoQ89349255
P2093author name stringShihua Wang
Zhao Sun
P2860cites workThe Hallmarks of CancerQ221226
Mesenchymal stem cells isolated from human uterine cervix cancer tissuesQ85100699
Clinical applications of mesenchymal stem cellsQ21198864
Origins of the tumor microenvironment: quantitative assessment of adipose-derived and bone marrow-derived stromaQ27309626
Mesenchymal stem cells within tumour stroma promote breast cancer metastasisQ29614303
The pro-inflammatory peptide LL-37 promotes ovarian tumor progression through recruitment of multipotent mesenchymal stromal cells.Q30486489
Mesenchymal stem cells transmigrate between and directly through tumor necrosis factor-α-activated endothelial cells via both leukocyte-like and novel mechanismsQ30525829
Mesenchymal stem cells in early entry of breast cancer into bone marrowQ33346309
Human bone marrow mesenchymal stem cells display anti-cancer activity in SCID mice bearing disseminated non-Hodgkin's lymphoma xenograftsQ33618949
Tumour stromal cells derived from paediatric malignancies display MSC-like properties and impair NK cell cytotoxicityQ33698636
Effects of transplantation of adipose tissue-derived stem cells on prostate tumorQ33879286
Influence of bone marrow stromal microenvironment on forodesine-induced responses in CLL primary cellsQ34122323
TNFα-exposed bone marrow-derived mesenchymal stem cells promote locomotion of MDA-MB-231 breast cancer cells through transcriptional activation of CXCR3 ligand chemokinesQ34155350
Mesenchymal stem cells in inflammation microenvironment accelerates hepatocellular carcinoma metastasis by inducing epithelial-mesenchymal transitionQ34405052
Mesenchymal stem cell 1 (MSC1)-based therapy attenuates tumor growth whereas MSC2-treatment promotes tumor growth and metastasisQ34429538
The different immunoregulatory functions of mesenchymal stem cells in patients with low-risk or high-risk myelodysplastic syndromesQ34429788
Human bone marrow-derived MSCs can home to orthotopic breast cancer tumors and promote bone metastasisQ34473242
Breast cancer stem cells are regulated by mesenchymal stem cells through cytokine networksQ35001086
Effects of inflammatory factors on mesenchymal stem cells and their role in the promotion of tumor angiogenesis in colon cancerQ35107504
Mesenchymal stromal cells promote tumor growth through the enhancement of neovascularizationQ35136732
Human ovarian carcinoma–associated mesenchymal stem cells regulate cancer stem cells and tumorigenesis via altered BMP productionQ35142842
p53 activation of mesenchymal stromal cells partially abrogates microenvironment-mediated resistance to FLT3 inhibition in AML through HIF-1α-mediated down-regulation of CXCL12.Q35485832
Chimeric antigen receptor T cells shape myeloid cell function within the tumor microenvironment through IFN-γ and GM-CSF.Q36016640
Bone marrow-derived myofibroblasts are the providers of pro-invasive matrix metalloproteinase 13 in primary tumorQ36343778
Comparison of the characteristics of mesenchymal stem cells obtained from prostate tumors and from bone marrow cultured in conditioned mediumQ36409234
CCR2-dependent recruitment of macrophages by tumor-educated mesenchymal stromal cells promotes tumor development and is mimicked by TNFαQ36456715
Hypoxia-inducible factor-dependent breast cancer-mesenchymal stem cell bidirectional signaling promotes metastasisQ36497267
Creating a tumor-resistant microenvironment: cell-mediated delivery of TNFα completely prevents breast cancer tumor formation in vivo.Q36654392
Tumor-promoting immune-suppressive myeloid-derived suppressor cells in the multiple myeloma microenvironment in humansQ36761567
Study of the quantitative, functional, cytogenetic, and immunoregulatory properties of bone marrow mesenchymal stem cells in patients with B-cell chronic lymphocytic leukemiaQ36776849
The tumor microenvironment and its role in promoting tumor growthQ36946019
The proinflammatory myeloid cell receptor TREM-1 controls Kupffer cell activation and development of hepatocellular carcinomaQ36959905
Regulation of CXCR4 expression in human mesenchymal stem cells by cytokine treatment: role in homing efficiency in NOD/SCID mice.Q50963245
Impairment in immuno-modulatory function of Flk1(+)CD31(-)CD34(-) MSCs from MDS-RA patients.Q51047920
Isolation and comparison of mesenchymal stem-like cells from human gastric cancer and adjacent non-cancerous tissues.Q53323838
Cancers as wounds that do not heal: differences and similarities between renal regeneration/repair and renal cell carcinoma.Q53343847
Human mesenchymal stem cells inhibit cancer cell proliferation by secreting DKK-1.Q54498583
Critical features of FAK-expressing AML bone marrow microenvironment through leukemia stem cell hijacking of mesenchymal stromal cells.Q54584460
Mesenchymal stromal cells from primary osteosarcoma are non-malignant and strikingly similar to their bone marrow counterparts.Q54647133
Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animalsQ62083511
Mesenchymal stem cell-like cells derived from human gastric cancer tissuesQ82266737
Mesenchymal stem cells enhance growth and metastasis of colon cancerQ84233035
Impaired osteogenic differentiation of mesenchymal stem cells derived from multiple myeloma patients is associated with a blockade in the deactivation of the Notch signaling pathwayQ84264128
MSC and Tumors: Homing, Differentiation, and Secretion Influence Therapeutic PotentialQ84992912
Mesenchymal stem cells promote tumor engraftment and metastatic colonization in rat osteosarcoma modelQ85041679
CD133: a stem cell biomarker and beyondQ36982860
In vitro evidence of the presence of mesenchymal stromal cells in cervical cancer and their role in protecting cancer cells from cytotoxic T cell activity.Q37143714
Concentration-dependent inhibition of angiogenesis by mesenchymal stem cellsQ37176533
Immunosuppressive effect of bone marrow-derived mesenchymal stem cells in inflammatory microenvironment favours the growth of B16 melanoma cellsQ37294845
Matrix metalloproteinase 1 is necessary for the migration of human bone marrow-derived mesenchymal stem cells toward human glioma.Q37407113
Tumour-associated fibroblasts and mesenchymal stem cells: more similarities than differencesQ37580254
Understanding tumor-stroma interplays for targeted therapies by armed mesenchymal stromal progenitors: the MesenkillersQ37948053
Infiltrating bone marrow mesenchymal stem cells increase prostate cancer stem cell population and metastatic ability via secreting cytokines to suppress androgen receptor signalingQ39136417
Tumor promotion through the mesenchymal stem cell compartment in human hepatocellular carcinoma.Q39143427
BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma.Q39212469
Syndecan-1 modulates β-integrin-dependent and interleukin-6-dependent functions in breast cancer cell adhesion, migration, and resistance to irradiationQ39216398
Interstitial flow in a 3D microenvironment increases glioma invasion by a CXCR4-dependent mechanismQ39219986
Mesenchymal stem cells regulate epithelial-mesenchymal transition and tumor progression of pancreatic cancer cellsQ39250469
Mesenchymal stem cells promote growth and angiogenesis of tumors in miceQ39255668
NF-κB activity regulates mesenchymal stem cell accumulation at tumor sitesQ39259185
Human bone marrow-derived mesenchymal stem cells suppress human glioma growth through inhibition of angiogenesis.Q39266457
Human mesenchymal stem cell and epithelial hepatic carcinoma cell lines in admixture: concurrent stimulation of cancer-associated fibroblasts and epithelial-to-mesenchymal transition markersQ39287485
Interleukin-1α induces immunosuppression by mesenchymal stem cells promoting the growth of prostate cancer cellsQ39296936
Mesenchymal stem cells provide an advantageous tumor microenvironment for the restoration of cancer stem cellsQ39333106
Glioma cells promote the expression of vascular cell adhesion molecule-1 on bone marrow-derived mesenchymal stem cells: a possible mechanism for their tropism toward gliomasQ39352864
Prospective dual role of mesenchymal stem cells in breast tumor microenvironmentQ39446303
Exosomes from breast cancer cells can convert adipose tissue-derived mesenchymal stem cells into myofibroblast-like cellsQ39476832
Exosomes from ovarian cancer cells induce adipose tissue-derived mesenchymal stem cells to acquire the physical and functional characteristics of tumor-supporting myofibroblastsQ39477145
Adipose derived stem cells (ASCs) isolated from breast cancer tissue express IL-4, IL-10 and TGF-β1 and upregulate expression of regulatory molecules on T cells: do they protect breast cancer cells from the immune response?Q39640772
Interleukin 6 mediated recruitment of mesenchymal stem cells to the hypoxic tumor milieuQ39679811
Potential role of mesenchymal stem cells (MSCs) in the breast tumour microenvironment: stimulation of epithelial to mesenchymal transition (EMT).Q39750162
Activation of signal transducers and activators of transcription 3 and focal adhesion kinase by stromal cell-derived factor 1 is required for migration of human mesenchymal stem cells in response to tumor cell-conditioned mediumQ39863427
Human mesenchymal stem cells (hMSCs) target osteosarcoma and promote its growth and pulmonary metastasis.Q39864787
Therapeutic potential of mesenchymal stromal cells in a mouse breast cancer metastasis modelQ39869090
Tissue-resident stem cells promote breast cancer growth and metastasisQ39889281
Suppression of tumorigenesis by human mesenchymal stem cells in a hepatoma modelQ39998770
The growth inhibitory effect of mesenchymal stem cells on tumor cells in vitro and in vivoQ40039805
Monocyte chemotactic protein-1 secreted by primary breast tumors stimulates migration of mesenchymal stem cells.Q40085462
Mesenchymal stem cells inhibit proliferation and apoptosis of tumor cells: impact on in vivo tumor growth.Q40195961
Dependency of colorectal cancer on a TGF-β-driven program in stromal cells for metastasis initiationQ41892760
Mesenchymal stem cells in non-small cell lung cancer--different from others? Insights from comparative molecular and functional analysesQ46522652
Colon cancer mesenchymal stem cells modulate the tumorigenicity of colon cancer through interleukin 6.Q46645861
Dkk-1 secreted by mesenchymal stem cells inhibits growth of breast cancer cells via depression of Wnt signallingQ47620825
P275copyright licenseCreative Commons Attribution 2.0 GenericQ19125117
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjecttumor microenvironmentQ1786433
mesenchymal stem cellQ1922379
inflammationQ101991
neoplasmQ1216998
neoplastic stem cellsQ1638475
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)14
P577publication date2014-02-06
P1433published inJournal of Hematology & OncologyQ15724593
P1476titleThe roles of mesenchymal stem cells in tumor inflammatory microenvironment
P478volume7

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cites work (P2860)
Q99584359A Novel Aurora Kinase Inhibitor Attenuates Leukemic Cell Proliferation Induced by Mesenchymal Stem Cells
Q35579236A novel inflammation-based prognostic score in esophageal squamous cell carcinoma: the C-reactive protein/albumin ratio.
Q36961794Adipose-Derived Stromal Vascular Fraction Differentially Expands Breast Progenitors in Tissue Adjacent to Tumors Compared to Healthy Breast Tissue.
Q35781395Adipose-derived stem cells promote tumor initiation and accelerate tumor growth by interleukin-6 production
Q64941271Adult Stem Cell Functioning in the Tumor Micro-Environment.
Q36134845All-trans retinoic acid arrests cell cycle in leukemic bone marrow stromal cells by increasing intercellular communication through connexin 43-mediated gap junction
Q50228598An Lysophosphatidic Acid Receptors 1 and 3 Axis Governs Cellular Senescence of Mesenchymal Stromal Cells and Promotes Growth and Vascularization of Multiple Myeloma
Q42540751BET protein inhibitor JQ1 inhibits growth and modulates WNT signaling in mesenchymal stem cells
Q92134661Bidirectional and Opposite Effects of Naïve Mesenchymal Stem Cells on Tumor Growth and Progression
Q38834400Bispecific antibody releasing-mesenchymal stromal cell machinery for retargeting T cells towards acute myeloid leukemia blasts.
Q49592081Bone marrow stromal cells enhance the survival of chronic lymphocytic leukemia cells by regulating HES-1 gene expression and H3K27me3 demethylation
Q26779818CCN: core regulatory proteins in the microenvironment that affect the metastasis of hepatocellular carcinoma?
Q92005618CD90low MSCs modulate intratumoral immunity to confer antitumor activity in a mouse model of ovarian cancer
Q36553208Cancer-associated fibroblasts promote the progression of endometrial cancer via the SDF-1/CXCR4 axis
Q38728887Cancer-associated mesenchymal stroma fosters the stemness of osteosarcoma cells in response to intratumoral acidosis via NF-κB activation
Q33808890Cell Connections by Tunneling Nanotubes: Effects of Mitochondrial Trafficking on Target Cell Metabolism, Homeostasis, and Response to Therapy
Q93200349Cell Culture Based in vitro Test Systems for Anticancer Drug Screening
Q41129906Chemotherapy-induced Dkk-1 expression by primary human mesenchymal stem cells is p53 dependent
Q47176438Curcumin inhibits gastric cancer-derived mesenchymal stem cells mediated angiogenesis by regulating NF-κB/VEGF signaling
Q28080901Cytokines, IBD, and colitis-associated cancer
Q98178384Development of Natural-Based Bone Cement for a Controlled Doxorubicin-Drug Release
Q99608849Dual Role of MSC-Derived Exosomes in Tumor Development
Q42320215Dux4 controls migration of mesenchymal stem cells through the Cxcr4-Sdf1 axis
Q48229004Effects of Human Mesenchymal Stem Cells Coculture on Calcium-Induced Differentiation of Normal Human Keratinocytes
Q36232448Exosomes derived from miR-122-modified adipose tissue-derived MSCs increase chemosensitivity of hepatocellular carcinoma
Q35237503Extracellular molecules involved in cancer cell invasion
Q37544362Functional and therapeutic relevance of hepatocyte growth factor/c-MET signaling in synovial sarcoma
Q35096615Galectin-3 mediates bone marrow microenvironment-induced drug resistance in acute leukemia cells via Wnt/β-catenin signaling pathway
Q35645718Gastric cancer-derived mesenchymal stem cells prompt gastric cancer progression through secretion of interleukin-8.
Q38259249Gene expression profiling for targeted cancer treatment
Q35984126Genetically modified "obligate" anaerobic Salmonella typhimurium as a therapeutic strategy for neuroblastoma.
Q37064043Genome-wide screen identified let-7c/miR-99a/miR-125b regulating tumor progression and stem-like properties in cholangiocarcinoma
Q57809350Human mesenchymal stem cells in the tumour microenvironment promote ovarian cancer progression: the role of platelet-activating factor
Q35586175Human mesenchymal stroma/stem cells exchange membrane proteins and alter functionality during interaction with different tumor cell lines
Q86957846Hypoxia-induced secretion of IL-10 from adipose-derived mesenchymal stem cell promotes growth and cancer stem cell properties of Burkitt lymphoma
Q64256786IL22 furthers malignant transformation of rat mesenchymal stem cells, possibly in association with IL22RA1/STAT3 signaling
Q38799898Inflammatory cytokines prime adipose tissue mesenchymal stem cells to enhance malignancy of MCF-7 breast cancer cells via transforming growth factor-β1.
Q51095214Influence of Mesenchymal Stem Cells Conditioned Media on Proliferation of Urinary Tract Cancer Cell Lines and Their Sensitivity to Ciprofloxacin.
Q36811167Lung tumor exosomes induce a pro-inflammatory phenotype in mesenchymal stem cells via NFκB-TLR signaling pathway
Q38638108Mesenchymal Stem Cells Relevance in Multicellular Bioengineered 3D In vitro Tumor Models
Q41695046Mesenchymal Stem Cells in Myeloid Malignancies: A Focus on Immune Escaping and Therapeutic Implications.
Q26746104Mesenchymal Stem and Progenitor Cells in Normal and Dysplastic Hematopoiesis-Masters of Survival and Clonality?
Q47701410Mesenchymal stem cells in the osteosarcoma microenvironment: their biological properties, influence on tumor growth, and therapeutic implications
Q39540701Mesenchymal stem cells promote pancreatic adenocarcinoma cells invasion by transforming growth factor-β1 induced epithelial-mesenchymal transition
Q58694827Mesenchymal stem cells recruited by castration-induced inflammation activation accelerate prostate cancer hormone resistance via chemokine ligand 5 secretion
Q37367538Mesenchymal stromal cells derived from cervical cancer produce high amounts of adenosine to suppress cytotoxic T lymphocyte functions
Q90683248Mesenchymal stromal cells in cancer: a review of their immunomodulatory functions and dual effects on tumor progression
Q91893596Mesenchymal stromal cells induce inhibitory effects on hepatocellular carcinoma through various signaling pathways
Q55155227Mutual Destruction of Deep Lung Tumor Tissues by Nanodrug-Conjugated Stealth Mesenchymal Stem Cells.
Q90292756New Insights Into Implementation of Mesenchymal Stem Cells in Cancer Therapy: Prospects for Anti-angiogenesis Treatment
Q92604691Notch-1 inhibition reduces proliferation and promotes osteogenic differentiation of bone marrow mesenchymal stem cells
Q64078436Novel insights into MSC-EVs therapy for immune diseases
Q27010088Obesity and weight loss could alter the properties of adipose stem cells?
Q38761193Opposite Effects of Coinjection and Distant Injection of Mesenchymal Stem Cells on Breast Tumor Cell Growth
Q36034029Physical Intimacy of Breast Cancer Cells with Mesenchymal Stem Cells Elicits Trastuzumab Resistance through Src Activation
Q47137932Preconditioning of murine mesenchymal stem cells synergistically enhanced immunomodulation and osteogenesis.
Q37564113Pro-inflammatory-Related Loss of CXCL12 Niche Promotes Acute Lymphoblastic Leukemic Progression at the Expense of Normal Lymphopoiesis
Q36658938Probiotics modulated gut microbiota suppresses hepatocellular carcinoma growth in mice
Q33795055Proteases Revisited: Roles and Therapeutic Implications in Fibrosis
Q89976335Recent Progress of Stem Cell Therapy in Cancer Treatment: Molecular Mechanisms and Potential Applications
Q55028526Reciprocal modulation of mesenchymal stem cells and tumor cells promotes lung cancer metastasis.
Q58092065Reciprocal reprogramming of cancer cells and associated Mesenchymal Stem Cells in gastric cancer
Q100696513Regional hyperthermia enhances mesenchymal stem cell recruitment to tumor stroma: Implications for mesenchymal stem cell-based tumor therapy
Q41488328Secretion of interleukin-6 by bone marrow mesenchymal stem cells promotes metastasis in hepatocellular carcinoma
Q42335714Self-assembling nanoparticles encapsulating zoledronic acid inhibit mesenchymal stromal cells differentiation, migration and secretion of proangiogenic factors and their interactions with prostate cancer cells.
Q47133839Skin-derived mesenchymal stem cells as quantum dot vehicles to tumors
Q37370810TNF-α augments CXCR2 and CXCR3 to promote progression of renal cell carcinoma
Q39390630Targeting interlukin-6 to relieve immunosuppression in tumor microenvironment
Q50116329The Angiogenic Chemokines Expression Profile of Myeloid Cell Lines Co-Cultured with Bone Marrow-Derived Mesenchymal Stem Cells
Q28074203The Complexity of Targeting PI3K-Akt-mTOR Signalling in Human Acute Myeloid Leukaemia: The Importance of Leukemic Cell Heterogeneity, Neighbouring Mesenchymal Stem Cells and Immunocompetent Cells
Q28263832The DACH/EYA/SIX gene network and its role in tumor initiation and progression
Q59797883The Dynamic Roles of Mesenchymal Stem Cells in Colon Cancer
Q38654867The Role of Tumor Microenvironment in Chemoresistance: To Survive, Keep Your Enemies Closer.
Q28073691The Roles of Mesenchymal Stromal/Stem Cells in Tumor Microenvironment Associated with Inflammation
Q39346175The Therapeutic Potential of Targeting Tumor Microenvironment in Breast Cancer: Rational Strategies and Recent Progress
Q26748595The clinical application of mesenchymal stromal cells in hematopoietic stem cell transplantation
Q54263670The distinct roles of mesenchymal stem cells in the initial and progressive stage of hepatocarcinoma.
Q92379262The hypoxia conditioned mesenchymal stem cells promote hepatocellular carcinoma progression through YAP mediated lipogenesis reprogramming
Q35592378The role of adipose-derived stem cells in breast cancer progression and metastasis.
Q92942865The role of mesenchymal stem cells in hematopoietic stem cell transplantation: prevention and treatment of graft-versus-host disease
Q28069049The role of tumor microenvironment in therapeutic resistance
Q94452292The voltage-gated proton channel hHv1 is functionally expressed in human chorion-derived mesenchymal stem cells
Q38811204Tumor Specific Recruitment and Reprogramming of Mesenchymal Stem Cells in Tumorigenesis
Q38758544Tumor-associated mesenchymal stem cells inhibit naïve T cell expansion by blocking cysteine export from dendritic cells
Q54982591Tumor-derived mesenchymal-stem-cell-secreted IL-6 enhances resistance to cisplatin via the STAT3 pathway in breast cancer.
Q42654111Tumor-educated mesenchymal stem cells promote pro-metastatic phenotype.
Q38356774Understanding the colon cancer stem cells and perspectives on treatment.
Q38808703Wnt5a-Ror2 signaling in mesenchymal stem cells promotes proliferation of gastric cancer cells by activating CXCL16-CXCR6 axis
Q33720928c-Kit-Positive Adipose Tissue-Derived Mesenchymal Stem Cells Promote the Growth and Angiogenesis of Breast Cancer.

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