TNFα-exposed bone marrow-derived mesenchymal stem cells promote locomotion of MDA-MB-231 breast cancer cells through transcriptional activation of CXCR3 ligand chemokines

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TNFα-exposed bone marrow-derived mesenchymal stem cells promote locomotion of MDA-MB-231 breast cancer cells through transcriptional activation of CXCR3 ligand chemokines is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.M110.128124
P932PMC publication ID2945567
P698PubMed publication ID20650898

P2093author name stringSoon Young Shin
Yoongho Lim
Young Han Lee
Jeong-Seok Nam
P2860cites workChemokines: novel targets for breast cancer metastasisQ36918688
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Anti-RhoA and anti-RhoC siRNAs inhibit the proliferation and invasiveness of MDA-MB-231 breast cancer cells in vitro and in vivo.Q40466398
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The expression of the chemokine receptor CXCR3 and its ligand, CXCL10, in human breast adenocarcinoma cell linesQ44842338
The CXC chemokines IP-10 and Mig are necessary for IL-12-mediated regression of the mouse RENCA tumorQ47816803
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GILZ, a glucocorticoid hormone induced gene, modulates T lymphocytes activation and death through interaction with NF-kBQ77441980
Chemokine receptor CXCR3 promotes colon cancer metastasis to lymph nodesQ79767236
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The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cellsQ24519206
Multilineage potential of adult human mesenchymal stem cellsQ27860737
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Cancer and the chemokine networkQ28269751
Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domainQ28281838
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretionQ29547317
Nuclear factor-kappaB in cancer development and progressionQ29547879
Mesenchymal stem cells within tumour stroma promote breast cancer metastasisQ29614303
NF-kappaB functions as a tumour promoter in inflammation-associated cancerQ29614598
Cell migration: Rho GTPases lead the wayQ29616711
Characterization of rac and cdc42 activation in chemoattractant-stimulated human neutrophils using a novel assay for active GTPasesQ29618793
Stromal fibroblasts in cancer initiation and progressionQ29618873
Molecular characterization of the tumor microenvironment in breast cancerQ31095898
Mesenchymal stem cell transition to tumor-associated fibroblasts contributes to fibrovascular network expansion and tumor progressionQ33427809
Stromal cells can contribute oncogenic signalsQ34231932
Chemokines in tumor angiogenesis and metastasisQ34540743
Smurf1 regulates tumor cell plasticity and motility through degradation of RhoA leading to localized inhibition of contractilityQ36117036
Role of chemokines in tumor growthQ36120825
Chemokines in tumor progression and metastasisQ36164084
Cancer CXC chemokine networks and tumour angiogenesisQ36410717
Matrix metalloproteinases and tumor metastasisQ36471104
The multifaceted roles of chemokines in malignancyQ36611120
Chemokine networks and breast cancer metastasis.Q36808485
P433issue40
P407language of work or nameEnglishQ1860
P921main subjectbreast cancerQ128581
bone marrowQ546523
mesenchymal stem cellQ1922379
P304page(s)30731-30740
P577publication date2010-07-22
P1433published inJournal of Biological ChemistryQ867727
P1476titleTNFα-exposed bone marrow-derived mesenchymal stem cells promote locomotion of MDA-MB-231 breast cancer cells through transcriptional activation of CXCR3 ligand chemokines
P478volume285

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