| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Domenico Tafuri | Q54251043 |
| Fabio Cattaneo | Q59683512 | ||
| Rosario Ammendola | Q60997845 | ||
| Melania Parisi | Q64224730 | ||
| P2093 | author name string | Germano Guerra | |
| Mariapia Cinelli | |||
| Marta De Marinis | |||
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| A reactive oxygen species-mediated, self-perpetuating loop persistently activates platelet-derived growth factor receptor α | Q24339412 | ||
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| G protein pathways | Q27919625 | ||
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| Oxidative and osmotic stress signaling in tumor cells is mediated by ADAM proteases and heparin-binding epidermal growth factor | Q40550725 | ||
| Reactive oxygen species mediate Met receptor transactivation by G protein-coupled receptors and the epidermal growth factor receptor in human carcinoma cells | Q40559771 | ||
| Multiple G-protein-coupled receptor signals converge on the epidermal growth factor receptor to promote migration and invasion | Q40612668 | ||
| Matrix metalloproteinases 2 and 9 mediate epidermal growth factor receptor transactivation by gonadotropin-releasing hormone | Q40636318 | ||
| Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors | Q41229236 | ||
| Regulation of receptor tyrosine kinase ligand processing | Q41994915 | ||
| Adenoviral-directed expression of the type 1A angiotensin receptor promotes cardiomyocyte hypertrophy via transactivation of the epidermal growth factor receptor | Q42162091 | ||
| Insulin-like growth factors mediate heterotrimeric G protein-dependent ERK1/2 activation by transactivating sphingosine 1-phosphate receptors. | Q50718278 | ||
| Insulin-like growth factor-I induces alpha(1B)-adrenergic receptor phosphorylation through G beta gamma and epidermal growth factor receptor transactivation. | Q51806428 | ||
| The paradigm of G protein receptor transactivation: a mechanistic definition and novel example. | Q54600760 | ||
| Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils | Q62658841 | ||
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| Epidermal growth factor (EGF) receptor-dependent ERK activation by G protein-coupled receptors: a co-culture system for identifying intermediates upstream and downstream of heparin-binding EGF shedding | Q73720739 | ||
| Calcium-dependent epidermal growth factor receptor transactivation mediates the angiotensin II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells | Q74424561 | ||
| The functional PDGFbeta receptor-S1P1 receptor signaling complex is involved in regulating migration of mouse embryonic fibroblasts in response to platelet derived growth factor | Q79921225 | ||
| Bombesin, bradykinin, vasopressin, and phorbol esters rapidly and transiently activate Src family tyrosine kinases in Swiss 3T3 cells. Dissociation from tyrosine phosphorylation of p125 focal adhesion kinase | Q42807633 | ||
| Detection of Neu1 Sialidase Activity in Regulating TOLL-like Receptor Activation | Q42870542 | ||
| Crosstalks between the receptors tyrosine kinase EGFR and TrkA and the GPCR, FPR, in human monocytes are essential for receptors-mediated cell activation | Q43010621 | ||
| Lysophosphatidic acid induces alphavbeta6 integrin-mediated TGF-beta activation via the LPA2 receptor and the small G protein G alpha(q). | Q43143386 | ||
| Nerve growth factor stimulation of p42/p44 mitogen-activated protein kinase in PC12 cells: role of G(i/o), G protein-coupled receptor kinase 2, beta-arrestin I, and endocytic processing | Q43641956 | ||
| Rapid transactivation of the vascular endothelial growth factor receptor KDR/Flk-1 by the bradykinin B2 receptor contributes to endothelial nitric-oxide synthase activation in cardiac capillary endothelial cells | Q43801362 | ||
| Calcium-independent activation of extracellularly regulated kinases 1 and 2 by angiotensin II in hepatic C9 cells: roles of protein kinase Cdelta, Src/proline-rich tyrosine kinase 2, and epidermal growth receptor trans-activation | Q43865604 | ||
| Maintenance of adrenergic vascular tone by MMP transactivation of the EGFR requires PI3K and mitochondrial ATP synthesis | Q44057590 | ||
| Involvement of HB-EGF and EGF receptor transactivation in TGF-beta-mediated fibronectin expression in mesangial cells | Q44091645 | ||
| Angiotensin II stimulation of NAD(P)H oxidase activity: upstream mediators | Q44128026 | ||
| Lysophosphatidic acid-induced squamous cell carcinoma cell proliferation and motility involves epidermal growth factor receptor signal transactivation | Q44203840 | ||
| Sphingosine 1-phosphate and platelet-derived growth factor (PDGF) act via PDGF beta receptor-sphingosine 1-phosphate receptor complexes in airway smooth muscle cells | Q44248239 | ||
| Transactivation joins multiple tracks to the ERK/MAPK cascade | Q44552387 | ||
| Nerve growth factor signaling involves interaction between the Trk A receptor and lysophosphatidate receptor 1 systems: nuclear translocation of the lysophosphatidate receptor 1 and Trk A receptors in pheochromocytoma 12 cells | Q44648530 | ||
| Agonist-induced activation of matrix metalloproteinase-7 promotes vasoconstriction through the epidermal growth factor-receptor pathway | Q44680897 | ||
| The 15-amino acid motif of the C terminus of the beta2-adrenergic receptor is sufficient to confer insulin-stimulated counterregulation to the beta1-adrenergic receptor | Q45075503 | ||
| Not so strange bedfellows: G-protein-coupled receptors and Src family kinases | Q45111099 | ||
| EGFR trans-activation by urotensin II receptor is mediated by β-arrestin recruitment and confers cardioprotection in pressure overload-induced cardiac hypertrophy. | Q45197667 | ||
| 5-HT(1A) receptors transactivate the platelet-derived growth factor receptor type beta in neuronal cells | Q45234394 | ||
| Role of EGF Receptor and Pyk2 in endothelin-1-induced ERK activation in rat cardiomyocytes | Q45711141 | ||
| Serotonin induces Rho/ROCK-dependent activation of Smads 1/5/8 in pulmonary artery smooth muscle cells | Q46108453 | ||
| Arachidonic acid release by H2O2 mediated proliferation of mouse embryonic stem cells: involvement of Ca2+/PKC and MAPKs-induced EGFR transactivation | Q46130498 | ||
| 4-Hydroxynonenal enhances MMP-2 production in vascular smooth muscle cells via mitochondrial ROS-mediated activation of the Akt/NF-kappaB signaling pathways | Q46355817 | ||
| c-Src-dependent transactivation of PDGFR contributes to TNF-α-induced MMP-9 expression and functional impairment in osteoblasts | Q46399877 | ||
| Gastric mucin secretion in response to beta-adrenergic G protein-coupled receptor activation is mediated by SRC kinase-dependent epidermal growth factor receptor transactivation | Q46573043 | ||
| Toll-like receptor signaling alters the expression of regulator of G protein signaling proteins in dendritic cells: implications for G protein-coupled receptor signaling | Q47726142 | ||
| Nox/Duox family of nicotinamide adenine dinucleotide (phosphate) oxidases | Q28213110 | ||
| IL-8 promotes cell proliferation and migration through metalloproteinase-cleavage proHB-EGF in human colon carcinoma cells | Q28238135 | ||
| The G protein G alpha(13) is required for growth factor-induced cell migration | Q28243364 | ||
| A role for chemokine receptor transactivation in growth factor signaling. | Q28360845 | ||
| Inhibition of xanthine oxidase by allopurinol prevents skeletal muscle atrophy: role of p38 MAPKinase and E3 ubiquitin ligases | Q28389456 | ||
| Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade | Q28505239 | ||
| Ligand-independent trans-activation of the platelet-derived growth factor receptor by reactive oxygen species requires protein kinase C-delta and c-Src | Q28565879 | ||
| Insulin induces heterologous desensitization of G-protein-coupled receptor and insulin-like growth factor I signaling by downregulating beta-arrestin-1. | Q28575441 | ||
| Differential transactivation of sphingosine-1-phosphate receptors modulates NGF-induced neurite extension | Q28577360 | ||
| Store-operated calcium channels | Q29617459 | ||
| Matrix metalloproteinases and the regulation of tissue remodelling | Q29618747 | ||
| EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF | Q29619098 | ||
| How matrix metalloproteinases regulate cell behavior | Q29620360 | ||
| Neurotensin stimulates mitogenesis of prostate cancer cells through a novel c-Src/Stat5b pathway | Q30441092 | ||
| Akt mediates sequestration of the beta(2)-adrenergic receptor in response to insulin | Q31036341 | ||
| N-acetylcysteine inhibits angiotensin ii-mediated activation of extracellular signal-regulated kinase and epidermal growth factor receptor | Q31856647 | ||
| Role of the sphingosine-1-phosphate receptor EDG-1 in PDGF-induced cell motility | Q32075112 | ||
| PACAP type I receptor transactivation is essential for IGF-1 receptor signalling and antiapoptotic activity in neurons | Q33276406 | ||
| Histamine stimulation of MMP-1(collagenase-1) secretion and gene expression in gastric epithelial cells: role of EGFR transactivation and the MAP kinase pathway | Q33291912 | ||
| A differential role for endocytosis in receptor-mediated activation of Nox1. | Q33818158 | ||
| NADPH-oxidase-dependent reactive oxygen species mediate EGFR transactivation by FPRL1 in WKYMVm-stimulated human lung cancer cells. | Q33944011 | ||
| GPR54 (KISS1R) transactivates EGFR to promote breast cancer cell invasiveness. | Q33955127 | ||
| Redox-dependent signal transduction | Q33957112 | ||
| Epidermal growth factor receptor signal transactivation | Q33973427 | ||
| Thrombin stimulation of proteoglycan synthesis in vascular smooth muscle is mediated by protease-activated receptor-1 transactivation of the transforming growth factor beta type I receptor | Q34094307 | ||
| The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals | Q34115674 | ||
| Cell communication networks: epidermal growth factor receptor transactivation as the paradigm for interreceptor signal transmission | Q34226003 | ||
| G-protein coupled receptor agonists mediate Neu1 sialidase and matrix metalloproteinase-9 cross-talk to induce transactivation of TOLL-like receptors and cellular signaling | Q34325053 | ||
| Hydrogen peroxide: a key messenger that modulates protein phosphorylation through cysteine oxidation | Q34467727 | ||
| Ligation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury. | Q34619626 | ||
| Distinct signaling cascades elicited by different formyl peptide receptor 2 (FPR2) agonists | Q34645842 | ||
| TNF-α and LPA promote synergistic expression of COX-2 in human colonic myofibroblasts: role of LPA-mediated transactivation of upregulated EGFR. | Q34729143 | ||
| Distinct mechanisms of receptor and nonreceptor tyrosine kinase activation by reactive oxygen species in vascular smooth muscle cells: role of metalloprotease and protein kinase C-delta | Q34819526 | ||
| GPCR/EGFR cross talk is conserved in gonadal and adrenal steroidogenesis but is uniquely regulated by matrix metalloproteinases 2 and 9 in the ovary. | Q35001269 | ||
| Reactive oxygen species are required for 5-HT-induced transactivation of neuronal platelet-derived growth factor and TrkB receptors, but not for ERK1/2 activation | Q35006469 | ||
| c-Jun N-terminal kinase activation by hydrogen peroxide in endothelial cells involves SRC-dependent epidermal growth factor receptor transactivation | Q38302532 | ||
| c-Src tyrosine kinase binds the beta 2-adrenergic receptor via phospho-Tyr-350, phosphorylates G-protein-linked receptor kinase 2, and mediates agonist-induced receptor desensitization | Q38302552 | ||
| Transactivation of vascular endothelial growth factor (VEGF) receptor Flk-1/KDR is involved in sphingosine 1-phosphate-stimulated phosphorylation of Akt and endothelial nitric-oxide synthase (eNOS). | Q38363037 | ||
| Sphingosine-1-phosphate-induced Flk-1 transactivation stimulates mouse embryonic stem cell proliferation through S1P1/S1P3-dependent β-arrestin/c-Src pathways | Q39075184 | ||
| A novel epidermal growth factor receptor-signaling platform and its targeted translation in pancreatic cancer | Q39102261 | ||
| Neu1 sialidase and matrix metalloproteinase-9 cross-talk regulates nucleic acid-induced endosomal TOLL-like receptor-7 and -9 activation, cellular signaling and pro-inflammatory responses | Q39130219 | ||
| WKYMVm-induced cross-talk between FPR2 and HGF receptor in human prostate epithelial cell line PNT1A. | Q39167016 | ||
| Intracellular signaling cascades triggered by the NK1 fragment of hepatocyte growth factor in human prostate epithelial cell line PNT1A. | Q39503087 | ||
| beta-Arrestin 2-mediated heterologous desensitization of IGF-IR by prolonged exposure of SH-SY5Y neuroblastoma cells to a mu opioid agonist | Q39678425 | ||
| S1P1 and VEGFR-2 form a signaling complex with extracellularly regulated kinase 1/2 and protein kinase C-alpha regulating ML-1 thyroid carcinoma cell migration | Q39700512 | ||
| FPRL1-mediated induction of superoxide in LL-37-stimulated IMR90 human fibroblast | Q39919686 | ||
| Protein kinase C-alpha and -delta are required for NADPH oxidase activation in WKYMVm-stimulated IMR90 human fibroblasts. | Q40197111 | ||
| A role for Fyn in Trk receptor transactivation by G-protein-coupled receptor signaling | Q40252573 | ||
| Transactivation of CXCR4 by the insulin-like growth factor-1 receptor (IGF-1R) in human MDA-MB-231 breast cancer epithelial cells | Q40371413 | ||
| Reactive oxygen species-dependent TNF-alpha converting enzyme activation through stimulation of 5-HT2B and alpha1D autoreceptors in neuronal cells | Q40403884 | ||
| P2Y2 nucleotide receptors enhance alpha-secretase-dependent amyloid precursor protein processing. | Q40444970 | ||
| Physiology and pathophysiology of matrix metalloproteases. | Q35007715 | ||
| Alpha1a-adrenoceptor genetic variant induces cardiomyoblast-to-fibroblast-like cell transition via distinct signaling pathways | Q35009145 | ||
| Oxidant signals and oxidative stress | Q35089394 | ||
| Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases | Q35201617 | ||
| Neu1 sialidase and matrix metalloproteinase-9 cross-talk is essential for Toll-like receptor activation and cellular signaling. | Q35378782 | ||
| Activation of tyrosine kinases by reactive oxygen species in vascular smooth muscle cells: significance and involvement of EGF receptor transactivation by angiotensin II. | Q35572619 | ||
| Phospholipase C and protein kinase C-β 2 mediate insulin-like growth factor II-dependent sphingosine kinase 1 activation | Q35595656 | ||
| Nox1 transactivation of epidermal growth factor receptor promotes N-cadherin shedding and smooth muscle cell migration | Q35766044 | ||
| Angiotensin II induces epithelial-to-mesenchymal transition in renal epithelial cells through reactive oxygen species/Src/caveolin-mediated activation of an epidermal growth factor receptor-extracellular signal-regulated kinase signaling pathway | Q35807271 | ||
| Engagement of β-arrestin by transactivated insulin-like growth factor receptor is needed for V2 vasopressin receptor-stimulated ERK1/2 activation | Q35921791 | ||
| Selective recruitment of G protein-coupled receptor kinases (GRKs) controls signaling of the insulin-like growth factor 1 receptor | Q35935789 | ||
| Beta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection. | Q35951476 | ||
| ADAMs as mediators of EGF receptor transactivation by G protein-coupled receptors | Q36504484 | ||
| Thrombin-mediated proteoglycan synthesis utilizes both protein-tyrosine kinase and serine/threonine kinase receptor transactivation in vascular smooth muscle cells. | Q36666309 | ||
| Receptor tyrosine kinase-G-protein coupled receptor complex signaling in mammalian cells | Q36751272 | ||
| Microvessel vascular smooth muscle cells contribute to collagen type I deposition through ERK1/2 MAP kinase, alphavbeta3-integrin, and TGF-beta1 in response to ANG II and high glucose | Q36807947 | ||
| Insulin-like growth factor receptor-1 stimulates phosphorylation of the beta2-adrenergic receptor in vivo on sites distinct from those phosphorylated in response to insulin | Q36831525 | ||
| Mitogenic signaling pathways induced by G protein-coupled receptors | Q36929839 | ||
| Regulated ADAM17-dependent EGF family ligand release by substrate-selecting signaling pathways | Q36932188 | ||
| β-arrestin-selective G protein-coupled receptor agonists engender unique biological efficacy in vivo | Q36932538 | ||
| GPCR-jacking: from a new route in RTK signalling to a new concept in GPCR activation | Q37000953 | ||
| Lysophosphatidic acid promoting corneal epithelial wound healing by transactivation of epidermal growth factor receptor | Q37150910 | ||
| Regulation of the proteolytic disintegrin metalloproteinases, the 'Sheddases'. | Q37289019 | ||
| beta-Arrestin mediates beta1-adrenergic receptor-epidermal growth factor receptor interaction and downstream signaling. | Q37339073 | ||
| Protein kinase C-delta transactivates platelet-derived growth factor receptor-alpha in mechanical strain-induced collagenase 3 (matrix metalloproteinase-13) expression by osteoblast-like cells | Q37377737 | ||
| Thrombin promotes matrix metalloproteinase-13 expression through the PKCδ c-Src/EGFR/PI3K/Akt/AP-1 signaling pathway in human chondrocytes. | Q37412533 | ||
| Mitochondrial reactive oxygen species mediate GPCR-induced TACE/ADAM17-dependent transforming growth factor-alpha shedding | Q37475351 | ||
| NADPH oxidases in cardiovascular disease. | Q37742824 | ||
| Dissecting how receptor tyrosine kinases modulate G protein-coupled receptor function. | Q37786673 | ||
| Active metalloproteases of the A Disintegrin and Metalloprotease (ADAM) family: biological function and structure. | Q37789733 | ||
| Expression and signaling of formyl-peptide receptors in the brain | Q37806144 | ||
| Receptor tyrosine kinase-G-protein-coupled receptor signalling platforms: out of the shadow? | Q37879733 | ||
| G protein coupled receptor transactivation: extending the paradigm to include serine/threonine kinase receptors. | Q37983353 | ||
| Therapeutic implications of endothelin and thrombin G-protein-coupled receptor transactivation of tyrosine and serine/threonine kinase cell surface receptors. | Q38089117 | ||
| ROS signalling between endothelial cells and cardiac cells | Q38193013 | ||
| Mutation of tyrosine-141 inhibits insulin-promoted tyrosine phosphorylation and increased responsiveness of the human beta 2-adrenergic receptor. | Q38289177 | ||
| P275 | copyright license | Creative Commons Attribution | Q6905323 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 11 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | G protein-coupled receptor | Q38173 |
| membrane protein | Q423042 | ||
| cell surface receptor | Q2476074 | ||
| P304 | page(s) | 19700-19728 | |
| P577 | publication date | 2014-10-29 | |
| P1433 | published in | International Journal of Molecular Sciences | Q3153277 |
| P1476 | title | Cell-surface receptors transactivation mediated by g protein-coupled receptors | |
| P478 | volume | 15 |
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