scholarly article | Q13442814 |
P50 | author | Dennis C. Liotta | Q5258252 |
Sommer S Zimmerman | Q125307341 | ||
Timothy M Acker | Q125308053 | ||
P2093 | author name string | Stephen F Traynelis | |
Brooke M Katzman | |||
Katie L Strong | |||
Rose M Santangelo | |||
P2860 | cites work | Genetic enhancement of learning and memory in mice | Q22010371 |
Glutamatergic drugs for schizophrenia: a systematic review and meta-analysis | Q22251177 | ||
Mechanism of memantine block of NMDA-activated channels in rat retinal ganglion cells: uncompetitive antagonism | Q24530210 | ||
Failures and successes of NMDA receptor antagonists: molecular basis for the use of open-channel blockers like memantine in the treatment of acute and chronic neurologic insults | Q24558984 | ||
Augmentation treatment of psychotherapy for anxiety disorders with D-cycloserine | Q24684778 | ||
X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor | Q27658372 | ||
Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors | Q27670455 | ||
Structure of a glutamate-receptor ligand-binding core in complex with kainate | Q27765825 | ||
Salicylate induces tinnitus through activation of cochlear NMDA receptors | Q28195872 | ||
The chemical biology of clinically tolerated NMDA receptor antagonists | Q28248958 | ||
Interaction between the C terminus of NMDA receptor subunits and multiple members of the PSD-95 family of membrane-associated guanylate kinases | Q28276144 | ||
Effects of the novel NMDA-receptor antagonist SDZ EAA 494 on memory and attention in humans | Q28286171 | ||
Glutamate-based therapeutic approaches: clinical trials with NMDA antagonists | Q28287381 | ||
Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95 | Q28290055 | ||
Glutamate receptor ion channels: structure, regulation, and function | Q28290774 | ||
Dextromethorphan Plus Ultra Low‐Dose Quinidine Reduces Pseudobulbar Affect | Q28293218 | ||
Impairment of suckling response, trigeminal neuronal pattern formation, and hippocampal LTD in NMDA receptor epsilon 2 subunit mutant mice | Q28507147 | ||
Spinophilin regulates the formation and function of dendritic spines | Q28513720 | ||
Molecular determinants of coordinated proton and zinc inhibition of N-methyl-D-aspartate NR1/NR2A receptors | Q28776368 | ||
Magnesium gates glutamate-activated channels in mouse central neurones | Q29616237 | ||
Antidepressant effects of ketamine in depressed patients | Q29617327 | ||
Targeting glutamate synapses in schizophrenia | Q30460392 | ||
Memantine is a clinically well tolerated N-methyl-D-aspartate (NMDA) receptor antagonist--a review of preclinical data | Q30580986 | ||
Sensitivity of the N-methyl-D-aspartate receptor to polyamines is controlled by NR2 subunits. | Q49105286 | ||
Different sensitivities of NMDA receptor channel subtypes to non-competitive antagonists | Q49143194 | ||
Characterization of the binding site for a novel class of noncompetitive alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonists | Q50508039 | ||
Effects of the cognition impairer MK-801 on learning and memory in mice and rats | Q51020354 | ||
Common and uncommon behavioural effects of antagonists for different modulatory sites in the NMDA receptor/channel complex. | Q52061505 | ||
Study of a new schizophrenomimetic drug; sernyl. | Q52771570 | ||
Syntheses of fluorinated phencyclidine analogs | Q56565617 | ||
Deuterium isotope effects in studies of drug metabolism | Q57406406 | ||
Glycine potentiates the NMDA response in cultured mouse brain neurons | Q59050531 | ||
Amantadine in the Treatment of Parkinson's Disease | Q67214050 | ||
Isotope effects: definitions and consequences for pharmacologic studies | Q69571647 | ||
Changes in intracellular pH associated with glutamate excitotoxicity | Q72656556 | ||
Subunit specificity and mechanism of action of NMDA partial agonist D-cycloserine | Q43698580 | ||
Effects of NMDA receptor antagonists: implications for the pathophysiology of schizophrenia | Q44045578 | ||
N-methyl-D-aspartate antagonist D-APV selectively disrupts taste-potentiated odor aversion learning | Q44201970 | ||
Comparative studies of anthraquinone- and anthracene-tetraamines as blockers of N-methyl-D-aspartate receptors | Q44310262 | ||
Molecular determinants of proton-sensitive N-methyl-D-aspartate receptor gating. | Q44449900 | ||
Selective blockade of N-methyl-D-aspartate (NMDA)-induced convulsions by NMDA antagonists and putative glycine antagonists: relationship with phencyclidine-like behavioral effects | Q44596549 | ||
Long-term effects of ketamine: evidence for a persisting impairment of source memory in recreational users | Q45000247 | ||
Selective cognitive impairments associated with NMDA receptor blockade in humans | Q45222011 | ||
A study of the dose dependency of a glycine receptor antagonist in focal ischemia | Q45244171 | ||
Identification of subunit- and antagonist-specific amino acid residues in the N-Methyl-D-aspartate receptor glutamate-binding pocket | Q45295826 | ||
Zinc potentiates agonist-lnduced currents at certain splice variants of the NMDA receptor | Q45975434 | ||
Effect of fluorine substitution on the adrenergic properties of 3-(tert-butylamino)-1-(3,4-dihydroxyphenoxy)-2-propanol | Q46142192 | ||
Contribution of hippocampal and extra-hippocampal NR2B-containing NMDA receptors to performance on spatial learning tasks | Q46199208 | ||
Neurochemical, electrophysiological and pharmacological profiles of the selective inhibitor of the glycine transporter-1 SSR504734, a potential new type of antipsychotic | Q46547623 | ||
Subtype-dependence of N-methyl-D-aspartate receptor modulation by pregnenolone sulfate | Q46781045 | ||
Nickel differentially affects NMDA receptor channels in developing cultured rat neurons | Q46957767 | ||
Drugs acting at the strychnine-insensitive glycine receptor do not induce HSP-70 protein in the cingulate cortex | Q48171940 | ||
Aminoglycoside neurotoxicity involves NMDA receptor activation | Q48312701 | ||
A dopamine/D1 receptor/protein kinase A/dopamine- and cAMP-regulated phosphoprotein (Mr 32 kDa)/protein phosphatase-1 pathway regulates dephosphorylation of the NMDA receptor. | Q48329693 | ||
Interaction of memantine and amantadine with agonist-unbound NMDA-receptor channels in acutely isolated rat hippocampal neurons | Q48399177 | ||
Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain | Q48629603 | ||
Characterization of a novel putative cognition enhancer mediating facilitation of glycine effect on strychnine-resistant sites coupled to NMDA receptor complex | Q48643808 | ||
Synthesis and beta-adrenergic activities of R-fluoronaphthyloxypropanolamine | Q48738334 | ||
Four residues of the extracellular N-terminal domain of the NR2A subunit control high-affinity Zn2+ binding to NMDA receptors | Q48892598 | ||
Identification and mechanism of action of two histidine residues underlying high-affinity Zn2+ inhibition of the NMDA receptor | Q48913312 | ||
Magnesium for acute stroke (Intravenous Magnesium Efficacy in Stroke trial): randomised controlled trial | Q48913482 | ||
Benzyl-polyamines: novel, potent N-methyl-D-aspartate receptor antagonists | Q48950584 | ||
Channel blockers acting at N-methyl-D-aspartate receptors: differential effects of mutations in the vestibule and ion channel pore. | Q42670368 | ||
A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors. | Q42755069 | ||
Immunohistochemical localization of N-methyl-D-aspartate and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor subunits in the substantia nigra pars compacta of the rat. | Q30650460 | ||
A comparative assessment of the efficacy and side-effect liability of neuroprotective compounds in experimental stroke | Q31924104 | ||
The discriminative stimulus effects of N-methyl-D-aspartate glycine-site ligands in NMDA antagonist-trained rats | Q33720690 | ||
NMDA receptor hypofunction model of schizophrenia | Q33813143 | ||
Structural determinants of D-cycloserine efficacy at the NR1/NR2C NMDA receptors | Q33821292 | ||
Tinnitus Retraining Therapy (TRT) as a method for treatment of tinnitus and hyperacusis patients. | Q33845030 | ||
Selfotel in acute ischemic stroke : possible neurotoxic effects of an NMDA antagonist | Q33888681 | ||
Quinazolin-4-one derivatives: A novel class of noncompetitive NR2C/D subunit-selective N-methyl-D-aspartate receptor antagonists | Q34059951 | ||
International Union of Pharmacology. XXXIII. Mammalian gamma-aminobutyric acid(B) receptors: structure and function | Q34130831 | ||
Neuroprotective potential of ionotropic glutamate receptor antagonists. | Q34209297 | ||
Why did NMDA receptor antagonists fail clinical trials for stroke and traumatic brain injury? | Q34212543 | ||
Excitotoxic cell death | Q34245367 | ||
Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones | Q34255679 | ||
The NMDA receptor as a target for cognitive enhancement | Q34288139 | ||
The rise and fall of NMDA antagonists for ischemic stroke. | Q34307201 | ||
Control of assembly and function of glutamate receptors by the amino-terminal domain. | Q34310112 | ||
The NMDA receptor glycine modulatory site: a therapeutic target for improving cognition and reducing negative symptoms in schizophrenia | Q34327773 | ||
A steroid modulatory domain on NR2B controls N-methyl-D-aspartate receptor proton sensitivity | Q34332564 | ||
A novel family of negative and positive allosteric modulators of NMDA receptors. | Q34360000 | ||
Cognitive enhancers as adjuncts to psychotherapy: use of D-cycloserine in phobic individuals to facilitate extinction of fear | Q34364137 | ||
Synaptic plasticity and learning: selective impairment of learning rats and blockade of long-term potentiation in vivo by the N-methyl-D-aspartate receptor antagonist AP5. | Q34454517 | ||
Subunit arrangement and function in NMDA receptors | Q34466595 | ||
Pregnenolone sulfate: a positive allosteric modulator at the N-methyl-D-aspartate receptor | Q34503039 | ||
Glutamatergic mechanisms in schizophrenia | Q34504043 | ||
Differential effects of enrichment on learning and memory function in NR2B transgenic mice | Q34518861 | ||
NMDA receptor subunits: function and pharmacology. | Q34579640 | ||
Glycine and N-methyl-D-aspartate receptors: physiological significance and possible therapeutic applications. | Q34756031 | ||
An innovative design to establish proof of concept of the antidepressant effects of the NR2B subunit selective N-methyl-D-aspartate antagonist, CP-101,606, in patients with treatment-refractory major depressive disorder. | Q34881233 | ||
Associative learning performance is impaired in zebrafish (Danio rerio) by the NMDA-R antagonist MK-801. | Q35141531 | ||
Mechanism for noncompetitive inhibition by novel GluN2C/D N-methyl-D-aspartate receptor subunit-selective modulators | Q35415834 | ||
Specific sites within the ligand-binding domain and ion channel linkers modulate NMDA receptor gating | Q35514668 | ||
New advances in NMDA receptor pharmacology | Q35570829 | ||
Clinical trials in traumatic brain injury: lessons for the future | Q35608050 | ||
Structure-activity relationships for allosteric NMDA receptor inhibitors based on 2-naphthoic acid. | Q35718367 | ||
Rationale for and use of NMDA receptor antagonists in Parkinson's disease. | Q35784328 | ||
Spermine potentiation of recombinant N-methyl-D-aspartate receptors is affected by subunit composition | Q35883550 | ||
Facilitation of fear extinction by D-cycloserine: theoretical and clinical implications. | Q35909916 | ||
Subunit-selective allosteric inhibition of glycine binding to NMDA receptors | Q35971484 | ||
TCN 201 selectively blocks GluN2A-containing NMDARs in a GluN1 co-agonist dependent but non-competitive manner | Q36060938 | ||
Coumarin-3-carboxylic acid derivatives as potentiators and inhibitors of recombinant and native N-methyl-D-aspartate receptors | Q36089680 | ||
Differential binding properties of [3H]dextrorphan and [3H]MK-801 in heterologously expressed NMDA receptors | Q36303035 | ||
Allosteric agonists of 7TM receptors: expanding the pharmacological toolbox | Q36556801 | ||
NMDA receptors in clinical neurology: excitatory times ahead | Q36660216 | ||
A brief review of the pharmacologic and therapeutic aspects of memantine in Alzheimer's disease | Q36725234 | ||
Ketamine as a novel antidepressant: from synapse to behavior | Q36905864 | ||
Learning and memory in conditioned fear extinction: effects of D-cycloserine. | Q36913843 | ||
Potentiation of the NMDA receptor in the treatment of schizophrenia: focused on the glycine site | Q36954416 | ||
Structural rearrangements of NR1/NR2A NMDA receptors during allosteric inhibition. | Q37184815 | ||
Control of NMDA receptor function by the NR2 subunit amino-terminal domain | Q37418445 | ||
Allosteric modulators of NR2B-containing NMDA receptors: molecular mechanisms and therapeutic potential | Q37548763 | ||
Glutamate-based antidepressants: 20 years on. | Q37616806 | ||
Multiple signaling pathways involved in stimulation of osteoblast differentiation by N-methyl-D-aspartate receptors activation in vitro | Q37729509 | ||
NovelN-methyl-d-aspartate receptor antagonists: a review of compounds patented since 2006 | Q37807432 | ||
Molecular basis of NMDA receptor functional diversity. | Q37852112 | ||
Do NMDA antagonists protect against cerebral ischemia: are clinical trials warranted? | Q37859421 | ||
Noncompetitive excitatory amino acid receptor antagonists | Q37874604 | ||
Glutamate binding-site ligands of NMDA receptors | Q37968686 | ||
Pharmacological modulation of NMDA receptor activity and the advent of negative and positive allosteric modulators | Q37978091 | ||
Molecular basis of positive allosteric modulation of GluN2B NMDA receptors by polyamines | Q38254691 | ||
N1-dansyl-spermine and N1-(n-octanesulfonyl)-spermine, novel glutamate receptor antagonists: block and permeation of N-methyl-D-aspartate receptors | Q39456199 | ||
Control of proton sensitivity of the NMDA receptor by RNA splicing and polyamines | Q39474796 | ||
Identification and characterization of novel NMDA receptor antagonists selective for NR2A- over NR2B-containing receptors | Q39660859 | ||
Design, Synthesis, and Biological Evaluation of 3-Benzazepin-1-ols as NR2B-Selective NMDA Receptor Antagonists. | Q39722433 | ||
Mechanism of differential control of NMDA receptor activity by NR2 subunits | Q39858588 | ||
Synaptic plasticity in the hippocampus: LTP and LTD. | Q40694257 | ||
The NMDA receptor antagonist D-2-amino-5-phosphonopentanoate (D-AP5) impairs spatial learning and LTP in vivo at intracerebral concentrations comparable to those that block LTP in vitro | Q41089018 | ||
Control by asparagine residues of calcium permeability and magnesium blockade in the NMDA receptor | Q41603790 | ||
Structural and mechanistic determinants of a novel site for noncompetitive inhibition of GluN2D-containing NMDA receptors | Q41845872 | ||
Effect of NMDA- and strychnine-insensitive glycine site antagonists on NMDA-mediated convulsions and learning | Q42023254 | ||
The atypical neuroleptic profile of the glycine/N-methyl-D-aspartate receptor antagonist, L-701,324, in rodents | Q42556542 | ||
Determinants of trapping block of N-methyl-d-aspartate receptor channels. | Q42608277 | ||
Expression of NMDAR2D glutamate receptor subunit mRNA in neurochemically identified interneurons in the rat neostriatum, neocortex and hippocampus | Q42643759 | ||
P433 | issue | 11 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 1337-52 | |
P577 | publication date | 2012-11-01 | |
P1433 | published in | Expert Opinion on Therapeutic Patents | Q5421213 |
P1476 | title | Novel NMDA receptor modulators: an update | |
P478 | volume | 22 |
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