Investigating the transcriptional control of cardiovascular development

scientific article

Investigating the transcriptional control of cardiovascular development is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1161/CIRCRESAHA.116.302832
P3181OpenCitations bibliographic resource ID4307238
P932PMC publication ID4332409
P698PubMed publication ID25677518

P2093author name stringB. G. Bruneau
E. P. Nora
I. S. Kathiriya
P2860cites workThe rise of regulatory RNAQ22121998
An integrated encyclopedia of DNA elements in the human genomeQ22122150
Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiationQ24291385
Hairy-related transcription factors inhibit GATA-dependent cardiac gene expression through a signal-responsive mechanismQ24306881
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5Q24307366
Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene familyQ24311501
Mutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt-Oram syndromeQ24311600
The accessible chromatin landscape of the human genomeQ24595581
Hopx and Hdac2 Interact to Modulate Gata4 Acetylation and Embryonic Cardiac Myocyte ProliferationQ24597593
Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactorsQ24602111
Pioneer factors in embryonic stem cells and differentiationQ24604741
Differentiation of human embryonic stem cells and induced pluripotent stem cells to cardiomyocytes: a methods overviewQ24618089
Exome sequencing identifies MLL2 mutations as a cause of Kabuki syndromeQ24622470
A common allele on chromosome 9 associated with coronary heart diseaseQ24647989
Ultraconservation identifies a small subset of extremely constrained developmental enhancersQ24648269
The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulationQ37799722
Factor mediated gene priming in pluripotent stem cells sets the stage for lineage specificationQ37975996
Transcription factor pathways and congenital heart disease.Q37997218
Transcription factors: from enhancer binding to developmental controlQ38032407
Epigenetic obstacles encountered by transcription factors: reprogramming against all oddsQ38037969
Chromatin modulators as facilitating factors in cellular reprogramming.Q38133028
Chromatin looping and organization at developmentally regulated gene lociQ38135369
The architecture of gene expression: integrating dispersed cis-regulatory modules into coherent regulatory domainsQ38218406
In pursuit of design principles of regulatory sequencesQ38218965
The emergence of proteome-wide technologies: systematic analysis of proteins comes of age.Q38221025
Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylasesQ24682791
An Nkx2-5/Bmp2/Smad1 negative feedback loop controls heart progenitor specification and proliferationQ27863351
gridlock, an HLH gene required for assembly of the aorta in zebrafishQ28138188
A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactylyQ28184095
HES and HERP families: multiple effectors of the Notch signaling pathwayQ28205103
The gene tinman is required for specification of the heart and visceral muscles in DrosophilaQ28237885
Development and applications of CRISPR-Cas9 for genome engineeringQ28241526
FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiationQ28244293
A transcription factor collective defines cardiac cell fate and reflects lineage historyQ28258920
ChIP-Seq identification of weakly conserved heart enhancersQ28291198
Tbx5-hedgehog molecular networks are essential in the second heart field for atrial septationQ28509085
The cardiac transcription network modulated by Gata4, Mef2a, Nkx2.5, Srf, histone modifications, and microRNAsQ28512635
The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulationQ28513177
Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factorQ28587239
Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesisQ28587459
Reptilian heart development and the molecular basis of cardiac chamber evolutionQ28587652
Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factorsQ28589872
Baf60c is essential for function of BAF chromatin remodelling complexes in heart developmentQ28593688
A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and diseaseQ28594121
Characterization of the TBX5 binding site and analysis of mutations that cause Holt-Oram syndromeQ28594224
DNA-binding specificities of human transcription factorsQ28854562
Genome-wide association study identifies loci on 12q24 and 13q32 associated with tetralogy of FallotQ28943387
A common variant on chromosome 9p21 affects the risk of myocardial infarctionQ29614954
Spatial partitioning of the regulatory landscape of the X-inactivation centreQ29614999
Network motifs: theory and experimental approachesQ29615325
A map of the cis-regulatory sequences in the mouse genomeQ29615404
In vivo enhancer analysis of human conserved non-coding sequencesQ29616554
Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell linesQ29616799
Virus induction of human IFN beta gene expression requires the assembly of an enhanceosomeQ29616850
Master transcription factors and mediator establish super-enhancers at key cell identity genesQ29618062
In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytesQ29620599
Directed transdifferentiation of mouse mesoderm to heart tissue by defined factorsQ30489586
Chromatin remodelling complex dosage modulates transcription factor function in heart developmentQ30500285
Proteomic profiling of cardiac tissue by isolation of nuclei tagged in specific cell types (INTACT)Q30570718
Fine tuning of craniofacial morphology by distant-acting enhancersQ30576356
Genome-wide discovery of human heart enhancersQ33523952
Function-based identification of mammalian enhancers using site-specific integrationQ33559746
A subclass of bHLH proteins required for cardiac morphogenesisQ38287764
Involvement of multiple cis elements in basal- and alpha-adrenergic agonist-inducible atrial natriuretic factor transcription. Roles for serum response elements and an SP-1-like elementQ38288684
Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancerQ38324392
Developmental fate and cellular maturity encoded in human regulatory DNA landscapesQ38394827
A temporal chromatin signature in human embryonic stem cells identifies regulators of cardiac developmentQ38458441
A large permissive regulatory domain exclusively controls Tbx3 expression in the cardiac conduction system.Q39552302
Noncooperative interactions between transcription factors and clustered DNA binding sites enable graded transcriptional responses to environmental inputsQ39738882
Divergent roles for NK-2 class homeobox genes in cardiogenesis in flies and miceQ41023759
Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants.Q41067008
Polycomb repressive complex 2 regulates normal development of the mouse heartQ41259507
Heterokaryons of cardiac myocytes and fibroblasts reveal the lack of dominance of the cardiac muscle phenotypeQ41462553
Direct measurement of DNA affinity landscapes on a high-throughput sequencing instrumentQ41766380
Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis.Q41811528
Heart repair by reprogramming non-myocytes with cardiac transcription factorsQ41859789
Circuitry and dynamics of human transcription factor regulatory networksQ42150273
Dynamic and coordinated epigenetic regulation of developmental transitions in the cardiac lineageQ42215098
Cofactor-mediated restriction of GATA-1 chromatin occupancy coordinates lineage-specific gene expressionQ42322690
Shadow enhancers: frequently asked questions about distributed cis-regulatory information and enhancer redundancyQ42397517
Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signalingQ43152071
ENU induced mutations causing congenital cardiovascular anomaliesQ45153465
A transgenic mouse model for the simultaneous monitoring of ANF and BNP gene activity during heart development and diseaseQ45309014
Going the distance: a current view of enhancer actionQ46076458
Co-regulation of the atrial natriuretic factor and cardiac myosin light chain-2 genes during alpha-adrenergic stimulation of neonatal rat ventricular cells. Identification of cis sequences within an embryonic and a constitutive contractile protein gQ46155378
Transcriptional control: rheostat converted to on/off switchQ46965292
Targeted deletion of a branchial arch-specific enhancer reveals a role of dHAND in craniofacial developmentQ47614302
Control of early cardiac-specific transcription of Nkx2-5 by a GATA-dependent enhancer.Q47624561
Chamber-specific cardiac expression of Tbx5 and heart defects in Holt-Oram syndromeQ47955346
A new homeobox-containing gene, msh-2, is transiently expressed early during mesoderm formation of DrosophilaQ48250147
Distinct regulation of developmental and heart disease-induced atrial natriuretic factor expression by two separate distal sequences.Q50646119
The “occlusis” model of cell fate restrictionQ51897712
SnapShot: Transcription regulation: pausing.Q53254319
Cardiac septal and valvular dysmorphogenesis in mice heterozygous for mutations in the homeobox gene Nkx2-5Q73178362
PRC2 directly methylates GATA4 and represses its transcriptional activityQ35674575
Tbx5-dependent pathway regulating diastolic function in congenital heart disease.Q36535492
Mammalian RNA polymerase II core promoters: insights from genome-wide studiesQ36814333
Transcriptional elongation checkpoint control in development and diseaseQ36902905
Atrial identity is determined by a COUP-TFII regulatory network.Q36942935
The developmental genetics of congenital heart disease.Q37089736
ETS factors regulate Vegf-dependent arterial specificationQ37125672
Genome-wide association study of multiple congenital heart disease phenotypes identifies a susceptibility locus for atrial septal defect at chromosome 4p16.Q37222748
Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradationQ37404493
Segmental folding of chromosomes: a basis for structural and regulatory chromosomal neighborhoods?Q37418601
A common genetic variant within SCN10A modulates cardiac SCN5A expressionQ37679987
Rapid and pervasive changes in genome-wide enhancer usage during mammalian developmentQ37706673
Cis-acting sequences that modulate atrial natriuretic factor gene expressionQ33579604
A map of open chromatin in human pancreatic isletsQ33687905
Coregulation of transcription factor binding and nucleosome occupancy through DNA features of mammalian enhancers.Q33723246
Building the heart piece by piece: modularity of cis-elements regulating Nkx2-5 transcriptionQ33728762
Chromatin regulation by Brg1 underlies heart muscle development and diseaseQ33969388
Nuclear reprogramming to a pluripotent state by three approachesQ33980410
Genome-wide quantitative enhancer activity maps identified by STARR-seqQ34035127
Genetic basis of congenital cardiovascular malformationsQ34125381
Large-scale analysis of the regulatory architecture of the mouse genome with a transposon-associated sensorQ34172336
Heterogeneity of genetic modifiers ensures normal cardiac developmentQ34193363
Comprehensive genome-wide protein-DNA interactions detected at single-nucleotide resolutionQ34239260
Enhancers as information integration hubs in development: lessons from genomics.Q34266848
Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phaseQ34299819
BAF60 A, B, and Cs of muscle determination and renewalQ34316322
An endocardial pathway involving Tbx5, Gata4, and Nos3 required for atrial septum formationQ34320580
tinman and bagpipe: two homeo box genes that determine cell fates in the dorsal mesoderm of DrosophilaQ34335151
De novo mutations in histone-modifying genes in congenital heart disease.Q34344183
Cooperativity and rapid evolution of cobound transcription factors in closely related mammalsQ34361479
Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome positionQ34375601
Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variantsQ34377776
Direct reprogramming of human fibroblasts toward a cardiomyocyte-like stateQ34390637
Transcriptional enhancers: Intelligent enhanceosomes or flexible billboards?Q34391887
The roles of mediator complex in cardiovascular diseasesQ34416269
Reprogramming of human fibroblasts toward a cardiac fateQ34619852
TRACER: a resource to study the regulatory architecture of the mouse genomeQ34645234
An atlas of active enhancers across human cell types and tissuesQ34660689
Co-occupancy by multiple cardiac transcription factors identifies transcriptional enhancers active in heart.Q34805195
Experimental strategies for studying transcription factor-DNA binding specificitiesQ34832146
Chromatin sampling--an emerging perspective on targeting polycomb repressor proteinsQ34976950
Combinatorial binding predicts spatio-temporal cis-regulatory activityQ35011328
Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic dietQ35621184
Large-scale discovery of enhancers from human heart tissueQ35635739
A decade of 3C technologies: insights into nuclear organizationQ35674570
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectcirculatory systemQ11068
P304page(s)700-14
P577publication date2015-02-13
P1433published inCirculation ResearchQ2599020
P1476titleInvestigating the transcriptional control of cardiovascular development
P478volume116

Reverse relations

cites work (P2860)
Q33747402A Path to Implement Precision Child Health Cardiovascular Medicine
Q90974961A reference map of murine cardiac transcription factor chromatin occupancy identifies dynamic and conserved enhancers
Q47113021A transcribed enhancer dictates mesendoderm specification in pluripotency
Q38920317An update on the molecular diagnosis of congenital heart disease: focus on loss-of-function mutations
Q64114202Analysis of NKX2-5 in 439 Chinese Patients with Sporadic Atrial Septal Defect
Q90402112Cardiac Stem Cells in the Postnatal Heart: Lessons from Development
Q52718032Cardiomyocyte Maturation Requires TLR3 Activated Nuclear Factor Kappa B.
Q33685482Cnot3 enhances human embryonic cardiomyocyte proliferation by promoting cell cycle inhibitor mRNA degradation
Q89606489Expression of Hey2 transcription factor in the early embryonic ventricles is controlled through a distal enhancer by Tbx20 and Gata transcription factors
Q38758999GFRA2 Identifies Cardiac Progenitors and Mediates Cardiomyocyte Differentiation in a RET-Independent Signaling Pathway.
Q38733125Genetic and Developmental Basis of Cardiovascular Malformations
Q55478673Genome and epigenome analysis of monozygotic twins discordant for congenital heart disease.
Q30235239Heart Failure in Pediatric Patients With Congenital Heart Disease
Q88905957Heterogeneity of adult masseter muscle satellite cells with cardiomyocyte differentiation potential
Q51467057Liganded retinoic acid X receptor α represses connexin 43 through a potential retinoic acid response element in the promoter region.
Q48273909Myocardial transcription factors in diastolic dysfunction: clues for model systems and disease
Q52325867NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network.
Q100418595Patient-specific genomics and cross-species functional analysis implicate LRP2 in hypoplastic left heart syndrome
Q33616987Prenatal Exposure to a Maternal High-Fat Diet Affects Histone Modification of Cardiometabolic Genes in Newborn Rats.
Q28078894SWI/SNF-directed stem cell lineage specification: dynamic composition regulates specific stages of skeletal myogenesis
Q36133874Sequential Binding of MEIS1 and NKX2-5 on the Popdc2 Gene: A Mechanism for Spatiotemporal Regulation of Enhancers during Cardiogenesis
Q38920721Spatiotemporal regulation of enhancers during cardiogenesis
Q47882562Structure and function of the Nppa-Nppb cluster locus during heart development and disease
Q33682735Systematic identification and characterization of cardiac long intergenic noncoding RNAs in zebrafish
Q51524594Telomere Length Defines the Cardiomyocyte Differentiation Potency of Mouse Induced Pluripotent Stem Cells.
Q26738380The Current Landscape of Genetic Testing in Cardiovascular Malformations: Opportunities and Challenges
Q41620441The role of histone modification and a regulatory single-nucleotide polymorphism (rs2071166) in the Cx43 promoter in patients with TOF.
Q36327743Transcriptional Landscape of Cardiomyocyte Maturation

Search more.