review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | B. G. Bruneau | |
E. P. Nora | |||
I. S. Kathiriya | |||
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Mutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt-Oram syndrome | Q24311600 | ||
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Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactors | Q24602111 | ||
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Ultraconservation identifies a small subset of extremely constrained developmental enhancers | Q24648269 | ||
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Transcription factor pathways and congenital heart disease. | Q37997218 | ||
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An Nkx2-5/Bmp2/Smad1 negative feedback loop controls heart progenitor specification and proliferation | Q27863351 | ||
gridlock, an HLH gene required for assembly of the aorta in zebrafish | Q28138188 | ||
A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactyly | Q28184095 | ||
HES and HERP families: multiple effectors of the Notch signaling pathway | Q28205103 | ||
The gene tinman is required for specification of the heart and visceral muscles in Drosophila | Q28237885 | ||
Development and applications of CRISPR-Cas9 for genome engineering | Q28241526 | ||
FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation | Q28244293 | ||
A transcription factor collective defines cardiac cell fate and reflects lineage history | Q28258920 | ||
ChIP-Seq identification of weakly conserved heart enhancers | Q28291198 | ||
Tbx5-hedgehog molecular networks are essential in the second heart field for atrial septation | Q28509085 | ||
The cardiac transcription network modulated by Gata4, Mef2a, Nkx2.5, Srf, histone modifications, and microRNAs | Q28512635 | ||
The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation | Q28513177 | ||
Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor | Q28587239 | ||
Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis | Q28587459 | ||
Reptilian heart development and the molecular basis of cardiac chamber evolution | Q28587652 | ||
Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors | Q28589872 | ||
Baf60c is essential for function of BAF chromatin remodelling complexes in heart development | Q28593688 | ||
A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease | Q28594121 | ||
Characterization of the TBX5 binding site and analysis of mutations that cause Holt-Oram syndrome | Q28594224 | ||
DNA-binding specificities of human transcription factors | Q28854562 | ||
Genome-wide association study identifies loci on 12q24 and 13q32 associated with tetralogy of Fallot | Q28943387 | ||
A common variant on chromosome 9p21 affects the risk of myocardial infarction | Q29614954 | ||
Spatial partitioning of the regulatory landscape of the X-inactivation centre | Q29614999 | ||
Network motifs: theory and experimental approaches | Q29615325 | ||
A map of the cis-regulatory sequences in the mouse genome | Q29615404 | ||
In vivo enhancer analysis of human conserved non-coding sequences | Q29616554 | ||
Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines | Q29616799 | ||
Virus induction of human IFN beta gene expression requires the assembly of an enhanceosome | Q29616850 | ||
Master transcription factors and mediator establish super-enhancers at key cell identity genes | Q29618062 | ||
In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes | Q29620599 | ||
Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors | Q30489586 | ||
Chromatin remodelling complex dosage modulates transcription factor function in heart development | Q30500285 | ||
Proteomic profiling of cardiac tissue by isolation of nuclei tagged in specific cell types (INTACT) | Q30570718 | ||
Fine tuning of craniofacial morphology by distant-acting enhancers | Q30576356 | ||
Genome-wide discovery of human heart enhancers | Q33523952 | ||
Function-based identification of mammalian enhancers using site-specific integration | Q33559746 | ||
A subclass of bHLH proteins required for cardiac morphogenesis | Q38287764 | ||
Involvement of multiple cis elements in basal- and alpha-adrenergic agonist-inducible atrial natriuretic factor transcription. Roles for serum response elements and an SP-1-like element | Q38288684 | ||
Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer | Q38324392 | ||
Developmental fate and cellular maturity encoded in human regulatory DNA landscapes | Q38394827 | ||
A temporal chromatin signature in human embryonic stem cells identifies regulators of cardiac development | Q38458441 | ||
A large permissive regulatory domain exclusively controls Tbx3 expression in the cardiac conduction system. | Q39552302 | ||
Noncooperative interactions between transcription factors and clustered DNA binding sites enable graded transcriptional responses to environmental inputs | Q39738882 | ||
Divergent roles for NK-2 class homeobox genes in cardiogenesis in flies and mice | Q41023759 | ||
Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants. | Q41067008 | ||
Polycomb repressive complex 2 regulates normal development of the mouse heart | Q41259507 | ||
Heterokaryons of cardiac myocytes and fibroblasts reveal the lack of dominance of the cardiac muscle phenotype | Q41462553 | ||
Direct measurement of DNA affinity landscapes on a high-throughput sequencing instrument | Q41766380 | ||
Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis. | Q41811528 | ||
Heart repair by reprogramming non-myocytes with cardiac transcription factors | Q41859789 | ||
Circuitry and dynamics of human transcription factor regulatory networks | Q42150273 | ||
Dynamic and coordinated epigenetic regulation of developmental transitions in the cardiac lineage | Q42215098 | ||
Cofactor-mediated restriction of GATA-1 chromatin occupancy coordinates lineage-specific gene expression | Q42322690 | ||
Shadow enhancers: frequently asked questions about distributed cis-regulatory information and enhancer redundancy | Q42397517 | ||
Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling | Q43152071 | ||
ENU induced mutations causing congenital cardiovascular anomalies | Q45153465 | ||
A transgenic mouse model for the simultaneous monitoring of ANF and BNP gene activity during heart development and disease | Q45309014 | ||
Going the distance: a current view of enhancer action | Q46076458 | ||
Co-regulation of the atrial natriuretic factor and cardiac myosin light chain-2 genes during alpha-adrenergic stimulation of neonatal rat ventricular cells. Identification of cis sequences within an embryonic and a constitutive contractile protein g | Q46155378 | ||
Transcriptional control: rheostat converted to on/off switch | Q46965292 | ||
Targeted deletion of a branchial arch-specific enhancer reveals a role of dHAND in craniofacial development | Q47614302 | ||
Control of early cardiac-specific transcription of Nkx2-5 by a GATA-dependent enhancer. | Q47624561 | ||
Chamber-specific cardiac expression of Tbx5 and heart defects in Holt-Oram syndrome | Q47955346 | ||
A new homeobox-containing gene, msh-2, is transiently expressed early during mesoderm formation of Drosophila | Q48250147 | ||
Distinct regulation of developmental and heart disease-induced atrial natriuretic factor expression by two separate distal sequences. | Q50646119 | ||
The “occlusis” model of cell fate restriction | Q51897712 | ||
SnapShot: Transcription regulation: pausing. | Q53254319 | ||
Cardiac septal and valvular dysmorphogenesis in mice heterozygous for mutations in the homeobox gene Nkx2-5 | Q73178362 | ||
PRC2 directly methylates GATA4 and represses its transcriptional activity | Q35674575 | ||
Tbx5-dependent pathway regulating diastolic function in congenital heart disease. | Q36535492 | ||
Mammalian RNA polymerase II core promoters: insights from genome-wide studies | Q36814333 | ||
Transcriptional elongation checkpoint control in development and disease | Q36902905 | ||
Atrial identity is determined by a COUP-TFII regulatory network. | Q36942935 | ||
The developmental genetics of congenital heart disease. | Q37089736 | ||
ETS factors regulate Vegf-dependent arterial specification | Q37125672 | ||
Genome-wide association study of multiple congenital heart disease phenotypes identifies a susceptibility locus for atrial septal defect at chromosome 4p16. | Q37222748 | ||
Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation | Q37404493 | ||
Segmental folding of chromosomes: a basis for structural and regulatory chromosomal neighborhoods? | Q37418601 | ||
A common genetic variant within SCN10A modulates cardiac SCN5A expression | Q37679987 | ||
Rapid and pervasive changes in genome-wide enhancer usage during mammalian development | Q37706673 | ||
Cis-acting sequences that modulate atrial natriuretic factor gene expression | Q33579604 | ||
A map of open chromatin in human pancreatic islets | Q33687905 | ||
Coregulation of transcription factor binding and nucleosome occupancy through DNA features of mammalian enhancers. | Q33723246 | ||
Building the heart piece by piece: modularity of cis-elements regulating Nkx2-5 transcription | Q33728762 | ||
Chromatin regulation by Brg1 underlies heart muscle development and disease | Q33969388 | ||
Nuclear reprogramming to a pluripotent state by three approaches | Q33980410 | ||
Genome-wide quantitative enhancer activity maps identified by STARR-seq | Q34035127 | ||
Genetic basis of congenital cardiovascular malformations | Q34125381 | ||
Large-scale analysis of the regulatory architecture of the mouse genome with a transposon-associated sensor | Q34172336 | ||
Heterogeneity of genetic modifiers ensures normal cardiac development | Q34193363 | ||
Comprehensive genome-wide protein-DNA interactions detected at single-nucleotide resolution | Q34239260 | ||
Enhancers as information integration hubs in development: lessons from genomics. | Q34266848 | ||
Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase | Q34299819 | ||
BAF60 A, B, and Cs of muscle determination and renewal | Q34316322 | ||
An endocardial pathway involving Tbx5, Gata4, and Nos3 required for atrial septum formation | Q34320580 | ||
tinman and bagpipe: two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila | Q34335151 | ||
De novo mutations in histone-modifying genes in congenital heart disease. | Q34344183 | ||
Cooperativity and rapid evolution of cobound transcription factors in closely related mammals | Q34361479 | ||
Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position | Q34375601 | ||
Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants | Q34377776 | ||
Direct reprogramming of human fibroblasts toward a cardiomyocyte-like state | Q34390637 | ||
Transcriptional enhancers: Intelligent enhanceosomes or flexible billboards? | Q34391887 | ||
The roles of mediator complex in cardiovascular diseases | Q34416269 | ||
Reprogramming of human fibroblasts toward a cardiac fate | Q34619852 | ||
TRACER: a resource to study the regulatory architecture of the mouse genome | Q34645234 | ||
An atlas of active enhancers across human cell types and tissues | Q34660689 | ||
Co-occupancy by multiple cardiac transcription factors identifies transcriptional enhancers active in heart. | Q34805195 | ||
Experimental strategies for studying transcription factor-DNA binding specificities | Q34832146 | ||
Chromatin sampling--an emerging perspective on targeting polycomb repressor proteins | Q34976950 | ||
Combinatorial binding predicts spatio-temporal cis-regulatory activity | Q35011328 | ||
Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet | Q35621184 | ||
Large-scale discovery of enhancers from human heart tissue | Q35635739 | ||
A decade of 3C technologies: insights into nuclear organization | Q35674570 | ||
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | circulatory system | Q11068 |
P304 | page(s) | 700-14 | |
P577 | publication date | 2015-02-13 | |
P1433 | published in | Circulation Research | Q2599020 |
P1476 | title | Investigating the transcriptional control of cardiovascular development | |
P478 | volume | 116 |
Q33747402 | A Path to Implement Precision Child Health Cardiovascular Medicine |
Q90974961 | A reference map of murine cardiac transcription factor chromatin occupancy identifies dynamic and conserved enhancers |
Q47113021 | A transcribed enhancer dictates mesendoderm specification in pluripotency |
Q38920317 | An update on the molecular diagnosis of congenital heart disease: focus on loss-of-function mutations |
Q64114202 | Analysis of NKX2-5 in 439 Chinese Patients with Sporadic Atrial Septal Defect |
Q90402112 | Cardiac Stem Cells in the Postnatal Heart: Lessons from Development |
Q52718032 | Cardiomyocyte Maturation Requires TLR3 Activated Nuclear Factor Kappa B. |
Q33685482 | Cnot3 enhances human embryonic cardiomyocyte proliferation by promoting cell cycle inhibitor mRNA degradation |
Q89606489 | Expression of Hey2 transcription factor in the early embryonic ventricles is controlled through a distal enhancer by Tbx20 and Gata transcription factors |
Q38758999 | GFRA2 Identifies Cardiac Progenitors and Mediates Cardiomyocyte Differentiation in a RET-Independent Signaling Pathway. |
Q38733125 | Genetic and Developmental Basis of Cardiovascular Malformations |
Q55478673 | Genome and epigenome analysis of monozygotic twins discordant for congenital heart disease. |
Q30235239 | Heart Failure in Pediatric Patients With Congenital Heart Disease |
Q88905957 | Heterogeneity of adult masseter muscle satellite cells with cardiomyocyte differentiation potential |
Q51467057 | Liganded retinoic acid X receptor α represses connexin 43 through a potential retinoic acid response element in the promoter region. |
Q48273909 | Myocardial transcription factors in diastolic dysfunction: clues for model systems and disease |
Q52325867 | NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network. |
Q100418595 | Patient-specific genomics and cross-species functional analysis implicate LRP2 in hypoplastic left heart syndrome |
Q33616987 | Prenatal Exposure to a Maternal High-Fat Diet Affects Histone Modification of Cardiometabolic Genes in Newborn Rats. |
Q28078894 | SWI/SNF-directed stem cell lineage specification: dynamic composition regulates specific stages of skeletal myogenesis |
Q36133874 | Sequential Binding of MEIS1 and NKX2-5 on the Popdc2 Gene: A Mechanism for Spatiotemporal Regulation of Enhancers during Cardiogenesis |
Q38920721 | Spatiotemporal regulation of enhancers during cardiogenesis |
Q47882562 | Structure and function of the Nppa-Nppb cluster locus during heart development and disease |
Q33682735 | Systematic identification and characterization of cardiac long intergenic noncoding RNAs in zebrafish |
Q51524594 | Telomere Length Defines the Cardiomyocyte Differentiation Potency of Mouse Induced Pluripotent Stem Cells. |
Q26738380 | The Current Landscape of Genetic Testing in Cardiovascular Malformations: Opportunities and Challenges |
Q41620441 | The role of histone modification and a regulatory single-nucleotide polymorphism (rs2071166) in the Cx43 promoter in patients with TOF. |
Q36327743 | Transcriptional Landscape of Cardiomyocyte Maturation |
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