FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation

scientific article (publication date: 11 July 1997)

FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0092-8674(00)80318-9
P3181OpenCitations bibliographic resource ID4392442
P698PubMed publication ID9230307

P50authorMerlin CrossleyQ16732507
Mitchell J WeissQ57032299
P2093author name stringC Yu
S H Orkin
Y Fujiwara
C A Turner
J E Visvader
A P Tsang
P2860cites workDependence of globin gene expression in mouse erythroleukemia cells on the NF-E2 heterodimerQ40016988
Rescue of GATA-1-deficient embryonic stem cells by heterologous GATA-binding proteinsQ40021346
Hematopoiesis: how does it happen?Q40974492
Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosomeQ41743756
X-MyT1, a Xenopus C2HC-type zinc finger protein with a regulatory function in neuronal differentiationQ48056539
The Caenorhabditis elegans gene sem-4 controls neuronal and mesodermal cell development and encodes a zinc finger proteinQ48061840
Heterochromatin effects on the frequency and duration of LCR-mediated gene transcriptionQ52521712
Expression of an erythroid transcription factor in megakaryocytic and mast cell lineagesQ59098875
Vectors used for expression in mammalian cellsQ68877182
The T cell leukemia oncoprotein SCL/tal-1 is essential for development of all hematopoietic lineagesQ71214319
A "DIRECT-COLORING" THIOCHOLINE METHOD FOR CHOLINESTERASESQ76898743
A DNA-binding protein containing two widely separated zinc finger motifs that recognize the same DNA sequenceQ24306598
A palindromic regulatory site within vertebrate GATA-1 promoters requires both zinc fingers of the GATA-1 DNA-binding domain for high-affinity interactionQ24310787
Association of erythroid transcription factors: complexes involving the LIM protein RBTN2 and the zinc-finger protein GATA1Q24312053
OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteinsQ24313516
Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response elementQ24337763
Combinatorial control of muscle development by basic helix-loop-helix and MADS-box transcription factorsQ24594377
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform ExtractionQ25938986
spalt encodes an evolutionarily conserved zinc finger protein of novel structure which provides homeotic gene function in the head and tail region of the Drosophila embryoQ26782010
Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferaseQ27860571
ALY, a context-dependent coactivator of LEF-1 and AML-1, is required for TCRalpha enhancer functionQ28236099
Megakaryocytic and erythrocytic lineages share specific transcription factorsQ28280405
Transcription factor GATA-1 permits survival and maturation of erythroid precursors by preventing apoptosisQ28505824
Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1Q28508495
GATA4 transcription factor is required for ventral morphogenesis and heart tube formationQ28586495
Transcription factor GATA-3 is required for development of the T-cell lineageQ28587190
A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet developmentQ28591602
Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesisQ28592331
An early haematopoietic defect in mice lacking the transcription factor GATA-2Q28593072
Production of high-titer helper-free retroviruses by transient transfectionQ29547802
Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cellsQ29620250
Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper proteinQ29620253
The C-terminal zinc finger of GATA-1 or GATA-2 is sufficient to induce megakaryocytic differentiation of an early myeloid cell line.Q34059190
GATA-1 reprograms avian myelomonocytic cell lines into eosinophils, thromboblasts, and erythroblastsQ34311278
The oncogenic cysteine-rich LIM domain protein rbtn2 is essential for erythroid developmentQ34330300
Ectopic expression of a conditional GATA-2/estrogen receptor chimera arrests erythroid differentiation in a hormone-dependent manner.Q34365985
The erythroid-specific transcription factor Eryf1: a new finger proteinQ34543086
Differentiation in erythroleukemic cells and their somatic hybridsQ35066170
Self-association of the erythroid transcription factor GATA-1 mediated by its zinc finger domainsQ36550780
Erythroid-cell-specific properties of transcription factor GATA-1 revealed by phenotypic rescue of a gene-targeted cell lineQ36566131
cDNA cloning of murine Nrf 2 gene, coding for a p45 NF-E2 related transcription factor.Q36701423
Transcriptional activation and DNA binding by the erythroid factor GF-1/NF-E1/Eryf 1.Q38338431
Functional synergy and physical interactions of the erythroid transcription factor GATA-1 with the Krüppel family proteins Sp1 and EKLF.Q40016157
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectGATA binding protein 1Q14916153
Zinc finger protein, multitype 1Q21498462
P304page(s)109-119
P577publication date1997-07-01
P1433published inCellQ655814
P1476titleFOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation
P478volume90

Reverse relations

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Q24671782Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1
Q34318281Neurokinin-B transcription in erythroid cells: direct activation by the hematopoietic transcription factor GATA-1.
Q37673550Notch signaling specifies megakaryocyte development from hematopoietic stem cells.
Q40488277Notch signals inhibit the development of erythroid/megakaryocytic cells by suppressing GATA-1 activity through the induction of HES1.
Q50435707Novel dominant-negative mutant of GATA3 in HDR syndrome
Q42222360Novel insights into the pathogenesis of the Graffi murine leukemia retrovirus
Q40090214Novel role for EKLF in megakaryocyte lineage commitment
Q35207765Novel roles for GATA transcription factors in the regulation of steroidogenesis
Q42912284NuRD mediates activating and repressive functions of GATA-1 and FOG-1 during blood development
Q27642186Nuclear magnetic resonance structures of the zinc finger domain of human DNA polymerase-α
Q38319503Nuclear protein binding at the beta-myosin heavy chain A/T-rich element is enriched following increased skeletal muscle activity
Q36054011Nucleated red blood cells impact DNA methylation and expression analyses of cord blood hematopoietic cells
Q35998756Origins of leukaemia in children with Down syndrome
Q31060298PIAS1 Is a GATA4 SUMO Ligase That Regulates GATA4-Dependent Intestinal Promoters Independent of SUMO Ligase Activity and GATA4 Sumoylation
Q28202849PLZF induces megakaryocytic development, activates Tpo receptor expression and interacts with GATA1 protein
Q30958350PPB1, a putative spliced leader RNA gene transcription factor in Trypanosoma cruzi
Q57810287PR/SET Domain Family and Cancer: Novel Insights from the Cancer Genome Atlas
Q38700890PU.1 activation relieves GATA-1-mediated repression of Cebpa and Cbfb during leukemia differentiation.
Q36138617PU.1 and pRB Interact and Cooperate To Repress GATA-1 and Block Erythroid Differentiation
Q33383468Pathobiology of secondary immune thrombocytopenia
Q38349547Pentaprobe: a comprehensive sequence for the one-step detection of DNA-binding activities
Q35221646Phosphorylation of Krüppel-like factor 3 (KLF3/BKLF) and C-terminal binding protein 2 (CtBP2) by homeodomain-interacting protein kinase 2 (HIPK2) modulates KLF3 DNA binding and activity
Q37130781Phylogenetic and Structural Analysis of the Pluripotency Factor Sex-Determining Region Y box2 Gene of Camelus dromedarius (cSox2).
Q40860037Pim-1 kinase protects hematopoietic FDC cells from genotoxin-induced death
Q42599702Plac8 and Plac9, novel placental-enriched genes identified through microarray analysis
Q24291352Platelet characteristics in patients with X-linked macrothrombocytopenia because of a novel GATA1 mutation
Q22254766Potentiation of GATA-2 activity through interactions with the promyelocytic leukemia protein (PML) and the t(15;17)-generated PML-retinoic acid receptor alpha oncoprotein
Q24602111Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactors
Q24328803Protein Arginine Methyltransferase 1 Interacts with and Activates p38α to Facilitate Erythroid Differentiation
Q34533281Protein-protein interaction between Fli-1 and GATA-1 mediates synergistic expression of megakaryocyte-specific genes through cooperative DNA binding
Q43808287Purification of Human Recombinant GATA-1 from Bacteria: Implication for Protein-Protein Interaction Studies
Q36759660RETRACTED: The BCL11A transcription factor directly activates RAG gene expression and V(D)J recombination
Q28509186ROG, repressor of GATA, regulates the expression of cytokine genes
Q28137623Reciprocal interactions of Pit1 and GATA2 mediate signaling gradient-induced determination of pituitary cell types
Q37417073Regions outside the DNA-binding domain are critical for proper in vivo specificity of an archetypal zinc finger transcription factor
Q47069980Regulation of Drosophila friend of GATA gene, u-shaped, during hematopoiesis: a direct role for serpent and lozenge
Q42823439Regulation of activity of the transcription factor GATA-1 by acetylation
Q33785155Regulation of erythroid 5-aminolevulinate synthase expression during erythropoiesis
Q47873129Regulation of mouse p45 NF-E2 transcription by an erythroid-specific GATA-dependent intronic alternative promoter
Q35037420Regulatory effects of TLR2 on megakaryocytic cell function
Q34998176Relocalizing Genetic Loci into Specific Subnuclear Neighborhoods
Q33600935Requirements for utilization of CREB binding protein by hypersensitive site two of the beta-globin locus control region
Q35204669Resveratrol ameliorates TNFα‐mediated suppression of erythropoiesis in human CD34+ cells via modulation of NF‐κB signalling
Q36164515Role of GATA-1 in normal and neoplastic hemopoiesis
Q33789575Role of LDB1 in the transition from chromatin looping to transcription activation.
Q37353689Role of STAT3 and GATA-1 interactions in gamma-globin gene expression
Q35821075Role of the GATA family of transcription factors in andrology.
Q36512426Role of the GATA family of transcription factors in endocrine development, function, and disease
Q33963880Role of the GATA-1/FOG-1/NuRD pathway in the expression of human beta-like globin genes.
Q36255973Role of transcription factors C/EBPalpha and PU.1 in normal hematopoiesis and leukemia.
Q28591576SCL and associated proteins distinguish active from repressive GATA transcription factor complexes
Q40583533SCL assembles a multifactorial complex that determines glycophorin A expression.
Q35591443SCL/TAL1-mediated transcriptional network enhances megakaryocytic specification of human embryonic stem cells
Q30938289Selection of peptides with affinity for the N-terminal domain of GATA-1: Identification of a potential interacting protein
Q37056319Self-association of Gata1 enhances transcriptional activity in vivo in zebra fish embryos
Q38334500Sequence determinants of DNA binding by the hematopoietic helix-loop-helix transcription factor TAL1: importance of sequences flanking the E-box core
Q33981947Sequences downstream of the erythroid promoter are required for high level expression of the human alpha-spectrin gene
Q33387092Severe gastrointestinal bleeding and thrombocytopenia in a child with an anti-GATA1 autoantibody
Q36335640Signal transduction pathways, intrinsic regulators, and the control of cell fate choice
Q35951832Signaling pathways in Th2 development
Q37622757Ski negatively regulates erythroid differentiation through its interaction with GATA1.
Q27628365Solution structures of two CCHC zinc fingers from the FOG family protein U-shaped that mediate protein-protein interactions
Q28513162Specific erythroid-lineage defect in mice conditionally deficient for Mediator subunit Med1
Q60046107Ssams2, a Gene Encoding GATA Transcription Factor, Is Required for Appressoria Formation and Chromosome Segregation in Sclerotinia sclerotiorum
Q34167985Stability and commitment in T helper cell development
Q101051148Stress erythropoiesis in atherogenic mice
Q27671779Structural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1
Q38302372Structure and specificity of GATA proteins in Th2 development
Q47987413Structure and transcriptional regulation of the mouse ferrochelatase gene
Q33323118Substitution of DNA-contacting amino acids with functional variants in the Gata-1 zinc finger: a structurally and phylogenetically guided mutagenesis
Q34107383Sumoylation regulates interaction of FOG1 with C-terminal-binding protein (CTBP)
Q28584770Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo
Q92135859Testicular Cancer: Genes, Environment, Hormones
Q28211777The CtBP family: enigmatic and enzymatic transcriptional co-repressors
Q47072467The Drosophila LIM-homeo domain protein Islet antagonizes pro-neural cell specification in the peripheral nervous system
Q34382445The Fission Yeast GATA Factor, Gaf1, Modulates Sexual Development via Direct Down-Regulation of ste11+ Expression in Response to Nitrogen Starvation
Q36305458The Friend of GATA proteins U-shaped, FOG-1, and FOG-2 function as negative regulators of blood, heart, and eye development in Drosophila
Q36254440The GATA factor Serpent cross-regulates lozenge and u-shaped expression during Drosophila blood cell development
Q38558334The GATA factor revolution in hematology
Q47763297The GATA family of transcription factors in Arabidopsis and rice.
Q27640551The Identification and Structure of an N-Terminal PR Domain Show that FOG1 Is a Member of the PRDM Family of Proteins
Q24311675The LIM-domain binding protein Ldb1 and its partner LMO2 act as negative regulators of erythroid differentiation
Q42824184The N termini of Friend of GATA (FOG) proteins define a novel transcriptional repression motif and a superfamily of transcriptional repressors
Q33953522The N-terminal zinc finger of the erythroid transcription factor GATA-1 binds GATC motifs in DNA.
Q34168378The NFY transcription factor inhibits von Willebrand factor promoter activation in non-endothelial cells through recruitment of histone deacetylases
Q40516013The Pal elements in the upstream glucokinase promoter exhibit dyad symmetry and display cell-specific enhancer activity when multimerised
Q64252935The Pleiotropic Effects of GATA1 and KLF1 in Physiological Erythropoiesis and in Dyserythropoietic Disorders
Q37625714The Promotion of Erythropoiesis via the Regulation of Reactive Oxygen Species by Lactic Acid
Q28245809The exosome complex establishes a barricade to erythroid maturation
Q35208763The function role of GATA-3 in Th1 and Th2 differentiation.
Q42802759The gene encoding the mitogen-responsive phosphoprotein Dab2 is differentially regulated by GATA-6 and GATA-4 in the visceral endoderm
Q90698672The histone H3K4 demethylase JARID1A directly interacts with haematopoietic transcription factor GATA1 in erythroid cells through its second PHD domain
Q35969109The homeobox gene DLX4 regulates erythro-megakaryocytic differentiation by stimulating IL-1β and NF-κB signaling
Q37520090The maize ID1 flowering time regulator is a zinc finger protein with novel DNA binding properties
Q33368674The molecular basis of congenital thrombocytopenias: insights into megakaryopoiesis
Q35158283The multitype zinc-finger protein U-shaped functions in heart cell specification in the Drosophila embryo
Q34578547The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages.
Q24297504The role of Ikaros in human erythroid differentiation
Q34892726The role of zinc finger protein 521/early hematopoietic zinc finger protein in erythroid cell differentiation
Q27618013The solution structure of the N-terminal zinc finger of GATA-1 reveals a specific binding face for the transcriptional co-factor FOG
Q24301783The transcription factor GATA-4 regulates cytochrome P4502C19 gene expression
Q28578134The zinc finger and C-terminal domains of MTA proteins are required for FOG-2-mediated transcriptional repression via the NuRD complex
Q35577420Thicker than blood: conserved mechanisms in Drosophila and vertebrate hematopoiesis
Q34294625Tissue-specific mitotic bookmarking by hematopoietic transcription factor GATA1.
Q41097181Transcription Factors in Eosinophil Development and As Therapeutic Targets
Q28251869Transcription factor GATA-1 and Down syndrome leukemogenesis
Q35847636Transcription factor GATA-1 potently represses the expression of the HIV-1 coreceptor CCR5 in human T cells and dendritic cells
Q35112203Transcription factor networks in erythroid cell and megakaryocyte development
Q34562988Transcription factors in cardiogenesis: the combinations that unlock the mysteries of the heart
Q37955972Transcription factors in parathyroid development: lessons from hypoparathyroid disorders
Q37122360Transcriptional Mechanisms Underlying Hemoglobin Synthesis
Q48037232Transcriptional Regulation of Interleukin-1β Gene by Interleukin-1β Itself Is Mediated in Part by Oct-1 in Thymic Stromal Cells
Q35196484Transcriptional activity of pannier is regulated negatively by heterodimerization of the GATA DNA-binding domain with a cofactor encoded by the u-shaped gene of Drosophila
Q24534136Transcriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingers
Q34700755Transcriptional control of erythropoiesis: emerging mechanisms and principles.
Q83327920Transcriptional regulation by GATA1 and GATA2 during erythropoiesis
Q34769966Transcriptional regulation of erythropoiesis. Fine tuning of combinatorial multi-domain elements.
Q28200921Transcriptional regulation of erythropoiesis: an affair involving multiple partners
Q39714792Transcriptional repression and developmental functions of the atypical vertebrate GATA protein TRPS1.
Q40575090Transforming acidic coiled-coil protein 3 (TACC3) controls friend of GATA-1 (FOG-1) subcellular localization and regulates the association between GATA-1 and FOG-1 during hematopoiesis
Q28510263Translational isoforms of FOG1 regulate GATA1-interacting complexes
Q86657049Two differential flows in a bioreactor promoted platelet generation from human pluripotent stem cell–derived megakaryocytes
Q34150163Two isoforms of Serpent containing either one or two GATA zinc fingers have different roles in Drosophila haematopoiesis
Q48237479Two zinc finger proteins from Mycobacterium smegmatis: DNA binding and activation of transcription
Q36445356Understanding mechanisms of gamma-globin gene regulation to develop strategies for pharmacological fetal hemoglobin induction
Q38781035Unlinking an lncRNA from Its Associated cis Element
Q28360504Uroporphyrinogen III synthase erythroid promoter mutations in adjacent GATA1 and CP2 elements cause congenital erythropoietic porphyria
Q74607084Use of altered specificity mutants to probe a specific protein-protein interaction in differentiation: the GATA-1:FOG complex
Q50471085Verification of the in vivo activity of three distinct cis-acting elements within the Gata1 gene promoter-proximal enhancer in mice
Q44519043Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor
Q52935421Wogonoside induces growth inhibition and cell cycle arrest via promoting the expression and binding activity of GATA-1 in chronic myelogenous leukemia cells
Q24291832X-linked thrombocytopenia caused by a novel mutation of GATA-1
Q24305399X-linked thrombocytopenia with thalassemia from a mutation in the amino finger of GATA-1 affecting DNA binding rather than FOG-1 interaction
Q50291341ZFPM proteins bind GATA proteins
Q38311500ZNF16 (HZF1) promotes erythropoiesis and megakaryocytopoiesis via regulation of the c-KIT gene
Q36275170Zebrafish atoh8 mutants do not recapitulate morpholino phenotypes
Q24306060Zinc Finger Protein, Multitype 1, Suppresses Human Th2 Development via Downregulation of IL-4
Q28200120Zinc finger proteins: new insights into structural and functional diversity
Q41710093Zinc fingers are sticking together
Q24557467Zinc fingers as protein recognition motifs: structural basis for the GATA-1/friend of GATA interaction
Q22010481hFOG-2, a novel zinc finger protein, binds the co-repressor mCtBP2 and modulates GATA-mediated activation
Q55000357miR-9 upregulation leads to inhibition of erythropoiesis by repressing FoxO3.
Q39213887p53-/- synergizes with enhanced NrasG12D signaling to transform megakaryocyte-erythroid progenitors in acute myeloid leukemia
Q35196208u-shaped encodes a zinc finger protein that regulates the proneural genesachaete and scute during the formation of bristles in Drosophila

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