Unveiling the intracellular survival gene kit of trypanosomatid parasites

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Unveiling the intracellular survival gene kit of trypanosomatid parasites is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PPAT.1004399
P932PMC publication ID4256449
P698PubMed publication ID25474314
P5875ResearchGate publication ID269169449

P50authorWanderson D DaRochaQ56840015
Santuza M R TeixeiraQ89636591
Daniella Castanheira BartholomeuQ41905720
P2093author name stringRita Marcia Cardoso de Paiva
Tiago A. O. Mendes
P2860cites workExpression of trypomastigote trans-sialidase in metacyclic forms of Trypanosoma cruzi increases parasite escape from its parasitophorous vacuole.Q51806092
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Role of the Leishmania surface protease gp63 in complement fixation, cell adhesion, and resistance to complement-mediated lysis.Q54162394
Molecular characterization of ribonucleoproteic antigens containing repeated amino acid sequences from Trypanosoma cruziQ56784471
Uptake, distribution, and oxidation of fatty acids by Leishmania mexicana amastigotesQ70183519
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A common pyrimidine-rich motif governs trans-splicing and polyadenylation of tubulin polycistronic pre-mRNA in trypanosomesQ72670719
Analysis of antisense and double stranded RNA downregulation of A2 protein expression in Leishmania donovaniQ73708772
Genetic complementation of Leishmania deficient in PSA (GP46) restores their resistance to lysis by complementQ80388336
T rypanosoma cruzi trans-sialidase as a multifunctional enzyme in Chagas' diseaseQ38022759
Cell signaling during Trypanosoma cruzi invasionQ38066485
The therapeutic potential of immune cross-talk in leishmaniasisQ38080581
Determinants of disease phenotype in trypanosomatid parasitesQ38221658
Trans-sialidase-like sequences from Trypanosoma congolense conserve most of the critical active site residues found in other trans-sialidasesQ38350428
The genome sequence of Leishmania (Leishmania) amazonensis: functional annotation and extended analysis of gene modelsQ39383991
LYT1 protein is required for efficient in vitro infection by Trypanosoma cruzi.Q39520750
Exclusion of synaptotagmin V at the phagocytic cup by Leishmania donovani lipophosphoglycan results in decreased promastigote internalization.Q39523134
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A conserved domain of the gp85/trans-sialidase family activates host cell extracellular signal-regulated kinase and facilitates Trypanosoma cruzi infectionQ40209151
Involvement of the stage-specific 82-kilodalton adhesion molecule of Trypanosoma cruzi metacyclic trypomastigotes in host cell invasion.Q40268502
Metacyclic neutralizing effect of monoclonal antibody 10D8 directed to the 35- and 50-kilodalton surface glycoconjugates of Trypanosoma cruziQ40427167
A leucine-rich repeat motif of Leishmania parasite surface antigen 2 binds to macrophages through the complement receptor 3.Q40569694
Leishmania inhibitor of serine peptidase 2 prevents TLR4 activation by neutrophil elastase promoting parasite survival in murine macrophagesQ42094091
Comparison of the A2 gene locus in Leishmania donovani and Leishmania major and its control over cutaneous infection.Q42602392
Overexpression of mitochondrial Leishmania major ascorbate peroxidase enhances tolerance to oxidative stress-induced programmed cell death and protein damage.Q42612561
RNA editing in kinetoplastidsQ43134637
Inhibitors of the major cysteinyl proteinase (GP57/51) impair host cell invasion and arrest the intracellular development of Trypanosoma cruzi in vitroQ43499829
Identification and characterization of a protein-tyrosine phosphatase in Leishmania: Involvement in virulenceQ43636703
The trans-sialidase from the african trypanosome Trypanosoma bruceiQ44033104
Repeat-enriched proteins are related to host cell invasion and immune evasion in parasitic protozoa.Q44045030
The Trypanosoma rangeli trypomastigote surfaceome reveals novel proteins and targets for specific diagnosisQ44048375
Evidence that intracellular beta1-2 mannan is a virulence factor in Leishmania parasitesQ44539316
The genome and its implicationsQ45224323
The Trypanosoma cruzi proteome.Q46601686
The evolution of amino acid repeat arrays in Plasmodium and other organismsQ48001317
Effect of A2 gene on infectivity of the nonpathogenic parasite Leishmania tarentolaeQ48059220
Comparative genomics of trypanosomatid parasitic protozoaQ29617953
Trypanosoma cruzi prolyl oligopeptidase Tc80 is involved in nonphagocytic mammalian cell invasion by trypomastigotes.Q30734130
Inhibitors of Leishmania mexicana CRK3 cyclin-dependent kinase: chemical library screen and antileishmanial activityQ31098941
Genomic organization and expression profile of the mucin-associated surface protein (masp) family of the human pathogen Trypanosoma cruziQ33425111
Chromosome level assembly of the hybrid Trypanosoma cruzi genomeQ33457699
Alpha-amanitin resistant transcription of protein coding genes in insect and bloodstream form Trypanosoma bruceiQ33591516
Upregulated expression of B-cell antigen family tandem repeat proteins by Leishmania amastigotesQ33826124
Oligopeptidase B-dependent signaling mediates host cell invasion by Trypanosoma cruziQ33889376
Glycosylation defects and virulence phenotypes of Leishmania mexicana phosphomannomutase and dolicholphosphate-mannose synthase gene deletion mutantsQ34012884
The mucin-like glycoprotein super-family of Trypanosoma cruzi: structure and biological roles.Q34264871
Tests of cytoplasmic RNA interference (RNAi) and construction of a tetracycline-inducible T7 promoter system in Trypanosoma cruzi.Q34286709
The MASP family of Trypanosoma cruzi: changes in gene expression and antigenic profile during the acute phase of experimental infectionQ34385087
Comparative genomic analysis of human infective Trypanosoma cruzi lineages with the bat-restricted subspecies T. cruzi marinkellei.Q34433425
Leishmania infection and virulenceQ34479946
Double-stranded RNA induces mRNA degradation in Trypanosoma bruceiQ34482588
Trypanosoma cruzi: role of δ-amastin on extracellular amastigote cell invasion and differentiationQ34525693
Intraphagosomal peroxynitrite as a macrophage-derived cytotoxin against internalized Trypanosoma cruzi: consequences for oxidative killing and role of microbial peroxiredoxins in infectivityQ34675951
The cell biology of Trypanosoma brucei differentiationQ34712659
Kinetoplastid phylogenetics, with special reference to the evolution of parasitic trypanosomesQ34835977
Lipophosphoglycan is a virulence factor distinct from related glycoconjugates in the protozoan parasite Leishmania major.Q35202576
RNA interference in protozoan parasites: achievements and challengesQ35271326
Chromosome and gene copy number variation allow major structural change between species and strains of LeishmaniaQ35581571
Genome sequencing of the lizard parasite Leishmania tarentolae reveals loss of genes associated to the intracellular stage of human pathogenic speciesQ35740567
Trypanosomatid comparative genomics: Contributions to the study of parasite biology and different parasitic diseasesQ35855383
A Leishmania amazonensis ZIP family iron transporter is essential for parasite replication within macrophage phagolysosomes.Q36227966
Surface sialic acids taken from the host allow trypanosome survival in tsetse fly vectorsQ36399214
Molecular basis of mammalian cell invasion by Trypanosoma cruziQ36419260
A differentially expressed gene family encoding "amastin," a surface protein of Trypanosoma cruzi amastigotes.Q36736149
Comparative genomics: from genotype to disease phenotype in the leishmaniasesQ36889371
Trypanosoma cruzi GP63 proteins undergo stage-specific differential posttranslational modification and are important for host cell infectionQ37191380
Heme uptake mediated by LHR1 is essential for Leishmania amazonensis virulenceQ37264659
A cytoplasmic new catalytic subunit of calcineurin in Trypanosoma cruzi and its molecular and functional characterizationQ37534167
Molecular mechanisms underlying the control of antigenic variation in African trypanosomesQ37795350
Host cell invasion by Trypanosoma cruzi: a unique strategy that promotes persistenceQ37984645
Genome of the avirulent human-infective trypanosome--Trypanosoma rangeliQ21092269
Predicting the proteins of Angomonas deanei, Strigomonas culicis and their respective endosymbionts reveals new aspects of the trypanosomatidae familyQ21133598
Comparative genomic analysis of three Leishmania species that cause diverse human diseaseQ21972828
The genome of the kinetoplastid parasite, Leishmania majorQ22065797
The Genome of the African Trypanosome Trypanosoma bruceiQ22065798
The Genome Sequence of Trypanosoma cruzi, Etiologic Agent of Chagas DiseaseQ22065799
The evolution of amastin surface glycoproteins in trypanosomatid parasitesQ24657394
Receptor-mediated phagocytosis of Leishmania: implications for intracellular survivalQ27025603
A novel cell surface trans-sialidase of trypanosoma cruzi generates a stage-specific epitope required for invasion of mammalian cellsQ28323919
Retention and loss of RNA interference pathways in trypanosomatid protozoansQ28475957
Shotgun sequencing analysis of Trypanosoma cruzi I Sylvio X10/1 and comparison with T. cruzi VI CL BrenerQ28477359
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectleishmaniasisQ331283
Trypanosoma cruziQ150162
African trypanosomiasisQ203133
Trypanosoma bruceiQ33244
LeishmaniaQ524818
protozoan genesQ70695532
Chagas diseaseQ649558
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)e1004399
P577publication date2014-12-01
P1433published inPLOS PathogensQ283209
P1476titleUnveiling the intracellular survival gene kit of trypanosomatid parasites
P478volume10

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cites work (P2860)
Q28548459A Novel Trypanosoma cruzi Protein Associated to the Flagellar Pocket of Replicative Stages and Involved in Parasite Growth
Q28551397Amastin Knockdown in Leishmania braziliensis Affects Parasite-Macrophage Interaction and Results in Impaired Viability of Intracellular Amastigotes
Q35682612Chromosomal copy number variation reveals differential levels of genomic plasticity in distinct Trypanosoma cruzi strains
Q66829246Current and promising novel drug candidates against visceral leishmaniasis
Q26772721Evasion of the Immune Response by Trypanosoma cruzi during Acute Infection
Q92375533Gene expression profiling of Trypanosoma cruzi in the presence of heme points to glycosomal metabolic adaptation of epimastigotes inside the vector
Q57050458Genomic assemblies of newly sequenced Trypanosoma cruzi strains reveal new genomic expansion and greater complexity
Q57790178Genomic comparison of Trypanosoma conorhini and Trypanosoma rangeli to Trypanosoma cruzi strains of high and low virulence
Q51574850Immune Modulation and Prevention of Autoimmune Disease by Repeated Sequences from Parasites Linked to Self Antigens.
Q35758446Leptomonas seymouri: Adaptations to the Dixenous Life Cycle Analyzed by Genome Sequencing, Transcriptome Profiling and Co-infection with Leishmania donovani
Q35840717Molecular Characterization of a Novel Family of Trypanosoma cruzi Surface Membrane Proteins (TcSMP) Involved in Mammalian Host Cell Invasion.
Q92663543Unveiling the partners of the DRBD2-mRNP complex, an RBP in Trypanosoma cruzi and ortholog to the yeast SR-protein Gbp2

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