Potential molecular targeting of splice variants for cancer treatment

scientific article

Potential molecular targeting of splice variants for cancer treatment is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID3253385
P698PubMed publication ID22126014

P2093author name stringChristopher A Blair
Xiaolin Zi
P2860cites workDistinct expression profiles for PTEN transcript and its splice variants in Cowden syndrome and Bannayan-Riley-Ruvalcaba syndrome.Q34658356
Silencing survivin splice variant 2B leads to antitumor activity in taxane--resistant ovarian cancerQ35024933
Drug insight: role of the androgen receptor in the development and progression of prostate cancerQ36773464
The generation and utilization of a cancer-oriented representation of the human transcriptome by using expressed sequence tagsQ37089379
Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistanceQ37145531
Anti-androgens and androgen-depleting therapies in prostate cancer: new agents for an established targetQ37606741
Development of antisense-mediated exon skipping as a treatment for duchenne muscular dystrophyQ38349983
Novel splice variant CAR 4/6 of the coxsackie adenovirus receptor is differentially expressed in cervical carcinogenesisQ39571698
Osteopontin-c splicing isoform contributes to ovarian cancer progression.Q39603458
Intragenic rearrangement and altered RNA splicing of the androgen receptor in a cell-based model of prostate cancer progressionQ39605639
Antisense inhibition of survivin expression as a cancer therapeuticQ39610362
Identification of novel truncated androgen receptor (AR) mutants including unreported pre-mRNA splicing variants in the 22Rv1 hormone-refractory prostate cancer (PCa) cell line.Q39787201
Local restoration of dystrophin expression with the morpholino oligomer AVI-4658 in Duchenne muscular dystrophy: a single-blind, placebo-controlled, dose-escalation, proof-of-concept studyQ24643018
A census of human cancer genesQ24647081
Discovery of novel splice forms and functional analysis of cancer-specific alternative splicing in human expressed sequencesQ24682430
Antisense-mediated exon skipping: a versatile tool with therapeutic and research applicationsQ24682555
Strengths and weaknesses of EST-based prediction of tissue-specific alternative splicingQ24798935
A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growthQ28116222
Genetic therapies for RNA mis-splicing diseasesQ28235690
Alternative splicing: increasing diversity in the proteomic worldQ29618730
Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancerQ30485336
Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variantQ30495758
Regulation of the inhibitor-of-apoptosis family member survivin in normal cord blood and bone marrow CD34(+) cells by hematopoietic growth factors: implication of survivin expression in normal hematopoiesisQ33182439
Pharmacological targeting of constitutively active truncated androgen receptor by nigericin and suppression of hormone-refractory prostate cancer cell growth.Q33658256
Protein diversity from alternative splicing: a challenge for bioinformatics and post-genome biologyQ34084341
Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptorQ34165500
Systemic administration of PRO051 in Duchenne's muscular dystrophyQ34172661
Anti-tumor activity of splice-switching oligonucleotidesQ34401490
The status of exon skipping as a therapeutic approach to duchenne muscular dystrophyQ34473336
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)836-839
P577publication date2011-11-01
P1433published inIndian Journal of Experimental BiologyQ2622243
P1476titlePotential molecular targeting of splice variants for cancer treatment
P478volume49

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cites work (P2860)
Q39163794Adult T-cell leukemia cells are characterized by abnormalities of Helios expression that promote T cell growth
Q26852848Alternative splicing for diseases, cancers, drugs, and databases
Q37240124Analysis of protein isoforms: can we do it better?
Q39393155Human kallikrein-related peptidase 12 (KLK12) splice variants expression in breast cancer and their clinical impact
Q36877029Review: Alternative Splicing (AS) of Genes As An Approach for Generating Protein Complexity.
Q49473342Splice variants of the endonucleases XPF and XPG contain residual DNA repair capabilities and could be a valuable tool for personalized medicine
Q35076912TIPMaP: a web server to establish transcript isoform profiles from reliable microarray probes

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