Adult T-cell leukemia cells are characterized by abnormalities of Helios expression that promote T cell growth

scientific article published on 19 May 2013

Adult T-cell leukemia cells are characterized by abnormalities of Helios expression that promote T cell growth is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/CAS.12181
P698PubMed publication ID23600753
P5875ResearchGate publication ID236249506

P50authorAtae UtsunomiyaQ98841128
P2093author name stringTadanori Yamochi
Kazumi Nakano
Masako Iwanaga
Seishi Ogawa
Toshiki Watanabe
Kazunari Yamaguchi
Masashi Sanada
Satsuki Muto
Aiko Sato-Otsubo
Makoto Yamagishi
Kaoru Uchimaru
Seiichiro Kobayashi
Satomi Asanuma
Katsuaki Kawanami
P2860cites workAiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiationQ24532162
Zinc finger-mediated protein interactions modulate Ikaros activity, a molecular control of lymphocyte developmentQ24561965
Helios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaros at centromeric heterochromatinQ24605629
The lymphoid transcription factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros geneQ24609038
PID: the Pathway Interaction DatabaseQ24656193
Potential molecular targeting of splice variants for cancer treatmentQ27008529
IKZF1 deletions predict relapse in uniformly treated pediatric precursor B-ALL.Q27851563
Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitmentQ28202932
Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitorsQ28268827
Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhingedQ28297381
Aiolos regulates B cell activation and maturation to effector stateQ28505020
Hes1 directly controls cell proliferation through the transcriptional repression of p27Kip1Q28508013
The Ikaros gene encodes a family of functionally diverse zinc finger DNA-binding proteinsQ28513108
Overexpression of novel short isoforms of Helios in a patient with T-cell acute lymphoblastic leukemiaQ34122448
Notch signaling contributes to proliferation and tumor formation of human T-cell leukemia virus type 1-associated adult T-cell leukemia.Q34151863
Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutationQ34412659
Human T lymphotropic virus type-I and adult T-cell leukemia in JapanQ34996357
Sphingosine-1-phosphate signaling and its role in diseaseQ35661485
The outs and the ins of sphingosine-1-phosphate in immunityQ36011196
Ikaros represses the transcriptional response to Notch signaling in T-cell developmentQ36994950
Deletion of IKZF1 and prognosis in acute lymphoblastic leukemiaQ37172988
Alternative splicing and tumor progressionQ37222930
Molecular hallmarks of adult T cell leukemiaQ38051633
Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: implications for a new mechanism of resistanceQ38289019
High-resolution analysis of chromosome copy number alterations in angioimmunoblastic T-cell lymphoma and peripheral T-cell lymphoma, unspecified, with single nucleotide polymorphism-typing microarraysQ38289220
HELIOS-BCL11B fusion gene involvement in a t(2;14)(q34;q32) in an adult T-cell leukemia patient.Q38322932
Ikaros directly represses the notch target gene Hes1 in a leukemia T cell line: implications for CD4 regulationQ39782908
Ikaros dominant negative isoform (Ik6) induces IL-3-independent survival of murine pro-B lymphocytes by activating JAK-STAT and up-regulating Bcl-xl levelsQ39984463
Characterization of the short isoform of Helios overexpressed in patients with T-cell malignanciesQ40171506
BCR-ABL1 induces aberrant splicing of IKAROS and lineage infidelity in pre-B lymphoblastic leukemia cellsQ40365403
LyF-1, a transcriptional regulator that interacts with a novel class of promoters for lymphocyte-specific genesQ40641439
Non-DNA-binding Ikaros isoform gene expressed in adult B-precursor acute lymphoblastic leukemiaQ40721250
Expression of a non-DNA-binding isoform of Helios induces T-cell lymphoma in mice.Q41819249
Sphingosine 1-phosphate receptor type 1 regulates egress of mature T cells from mouse bone marrowQ43055423
Expression of the Ikaros gene family in childhood acute lymphoblastic leukaemiaQ44004531
Overexpression of dominant-negative Ikaros 6 protein is restricted to a subset of B common adult acute lymphoblastic leukemias that express high levels of the CD34 antigenQ44443472
Human T-cell leukemia virus type I (HTLV-1) proviral load and disease progression in asymptomatic HTLV-1 carriers: a nationwide prospective study in JapanQ45376179
Diagnostic criteria and classification of clinical subtypes of adult T-cell leukaemia-lymphoma. A report from the Lymphoma Study Group (1984-87).Q46659532
Polycomb-mediated loss of miR-31 activates NIK-dependent NF-κB pathway in adult T cell leukemia and other cancers.Q55239231
Over-expression of short isoforms of Helios in patients with adult T-cell leukaemia/lymphoma.Q55239618
BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of IkarosQ57734316
A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphomaQ71806450
Dominant negative isoform of the Ikaros gene in patients with adult B-cell acute lymphoblastic leukemiaQ74181090
Expression of dominant-negative Ikaros isoforms in T-cell acute lymphoblastic leukemiaQ78206885
Expression of Ikaros isoform 6 in chinese children with acute lymphoblastic leukemiaQ84596956
P433issue8
P921main subjectleukemiaQ29496
cell growthQ189159
T-cell leukemiaQ7667895
P304page(s)1097-1106
P577publication date2013-05-19
P1433published inCancer ScienceQ326125
P1476titleAdult T-cell leukemia cells are characterized by abnormalities of Helios expression that promote T cell growth
P478volume104